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Found 22 hits Enz. Inhib. hit(s) with Target = 'Zn finger protein' AND taxid = 4097   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Zn finger protein


(Nicotiana tabacum)
BDBM50332026
PNG
(8-acetyl-7-propoxy-2H-chromen-2-one | CHEMBL128859...)
Show SMILES CCCOc1ccc2ccc(=O)oc2c1C(C)=O
Show InChI InChI=1S/C14H14O4/c1-3-8-17-11-6-4-10-5-7-12(16)18-14(10)13(11)9(2)15/h4-7H,3,8H2,1-2H3
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0.980n/an/an/an/an/an/an/an/a



Università degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CA12 catalytic domain by stopped-flow CO2 hydration method


Citation and Details
More data for this
Ligand-Target Pair
Zn finger protein


(Nicotiana tabacum)
BDBM50332025
PNG
(8-acetyl-7-ethoxy-2H-chromen-2-one | CHEMBL1288595)
Show SMILES CCOc1ccc2ccc(=O)oc2c1C(C)=O
Show InChI InChI=1S/C13H12O4/c1-3-16-10-6-4-9-5-7-11(15)17-13(9)12(10)8(2)14/h4-7H,3H2,1-2H3
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1n/an/an/an/an/an/an/an/a



Università degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CA12 catalytic domain by stopped-flow CO2 hydration method


Citation and Details
More data for this
Ligand-Target Pair
Zn finger protein


(Nicotiana tabacum)
BDBM50332027
PNG
(8-acetyl-7-butoxy-2H-chromen-2-one | CHEMBL1288620)
Show SMILES CCCCOc1ccc2ccc(=O)oc2c1C(C)=O
Show InChI InChI=1S/C15H16O4/c1-3-4-9-18-12-7-5-11-6-8-13(17)19-15(11)14(12)10(2)16/h5-8H,3-4,9H2,1-2H3
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8.80n/an/an/an/an/an/an/an/a



Università degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CA12 catalytic domain by stopped-flow CO2 hydration method


Citation and Details
More data for this
Ligand-Target Pair
Zn finger protein


(Nicotiana tabacum)
BDBM50332028
PNG
(8-acetyl-7-(benzyloxy)-2H-chromen-2-one | CHEMBL12...)
Show SMILES CC(=O)c1c(OCc2ccccc2)ccc2ccc(=O)oc12
Show InChI InChI=1S/C18H14O4/c1-12(19)17-15(21-11-13-5-3-2-4-6-13)9-7-14-8-10-16(20)22-18(14)17/h2-10H,11H2,1H3
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22.4n/an/an/an/an/an/an/an/a



Università degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CA12 catalytic domain by stopped-flow CO2 hydration method


Citation and Details
More data for this
Ligand-Target Pair
Zn finger protein


(Nicotiana tabacum)
BDBM50332030
PNG
(7-methoxy-8-propionyl-2H-chromen-2-one | CHEMBL128...)
Show SMILES CCC(=O)c1c(OC)ccc2ccc(=O)oc12
Show InChI InChI=1S/C13H12O4/c1-3-9(14)12-10(16-2)6-4-8-5-7-11(15)17-13(8)12/h4-7H,3H2,1-2H3
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26.3n/an/an/an/an/an/an/an/a



Università degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CA12 catalytic domain by stopped-flow CO2 hydration method


Citation and Details
More data for this
Ligand-Target Pair
Zn finger protein


(Nicotiana tabacum)
BDBM50332029
PNG
(8-Acetyl-7-(2-adamantan-1-yl-ethoxy)-chromen-2-one...)
Show SMILES CC(=O)c1c(OCCC23CC4CC(CC(C4)C2)C3)ccc2ccc(=O)oc12
Show InChI InChI=1S/C23H26O4/c1-14(24)21-19(4-2-18-3-5-20(25)27-22(18)21)26-7-6-23-11-15-8-16(12-23)10-17(9-15)13-23/h2-5,15-17H,6-13H2,1H3
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31.5n/an/an/an/an/an/an/an/a



Università degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CA12 catalytic domain by stopped-flow CO2 hydration method


Citation and Details
More data for this
Ligand-Target Pair
Zn finger protein


(Nicotiana tabacum)
BDBM50332031
PNG
(7-ethoxy-8-propionyl-2H-chromen-2-one | CHEMBL1288...)
Show SMILES CCOc1ccc2ccc(=O)oc2c1C(=O)CC
Show InChI InChI=1S/C14H14O4/c1-3-10(15)13-11(17-4-2)7-5-9-6-8-12(16)18-14(9)13/h5-8H,3-4H2,1-2H3
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33.2n/an/an/an/an/an/an/an/a



Università degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CA12 catalytic domain by stopped-flow CO2 hydration method


Citation and Details
More data for this
Ligand-Target Pair
Zn finger protein


(Nicotiana tabacum)
BDBM50332032
PNG
(8-Propionyl-7-propoxy-2H-chromen-2-one | CHEMBL128...)
Show SMILES CCCOc1ccc2ccc(=O)oc2c1C(=O)CC
Show InChI InChI=1S/C15H16O4/c1-3-9-18-12-7-5-10-6-8-13(17)19-15(10)14(12)11(16)4-2/h5-8H,3-4,9H2,1-2H3
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38.4n/an/an/an/an/an/an/an/a



Università degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CA12 catalytic domain by stopped-flow CO2 hydration method


Citation and Details
More data for this
Ligand-Target Pair
Zn finger protein


(Nicotiana tabacum)
BDBM50300203
PNG
((S)-6-(1-hydroxy-3-methylbutyl)-7-methoxy-2H-chrom...)
Show SMILES COc1cc2oc(=O)ccc2cc1[C@@H](O)CC(C)C
Show InChI InChI=1S/C15H18O4/c1-9(2)6-12(16)11-7-10-4-5-15(17)19-13(10)8-14(11)18-3/h4-5,7-9,12,16H,6H2,1-3H3/t12-/m0/s1
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48.6n/an/an/an/an/an/an/an/a



Università degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CA12 catalytic domain by stopped-flow CO2 hydration method


Citation and Details
More data for this
Ligand-Target Pair
Zn finger protein


(Nicotiana tabacum)
BDBM50332024
PNG
(8-acetyl-7-methoxy-2H-chromen-2-one | CHEMBL128859...)
Show SMILES COc1ccc2ccc(=O)oc2c1C(C)=O
Show InChI InChI=1S/C12H10O4/c1-7(13)11-9(15-2)5-3-8-4-6-10(14)16-12(8)11/h3-6H,1-2H3
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60.9n/an/an/an/an/an/an/an/a



Università degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CA12 catalytic domain by stopped-flow CO2 hydration method


Citation and Details
More data for this
Ligand-Target Pair
Zn finger protein


(Nicotiana tabacum)
BDBM50332037
PNG
(7-hydroxy-8-propionyl-2H-chromen-2-one | CHEMBL128...)
Show SMILES CCC(=O)c1c(O)ccc2ccc(=O)oc12
Show InChI InChI=1S/C12H10O4/c1-2-8(13)11-9(14)5-3-7-4-6-10(15)16-12(7)11/h3-6,14H,2H2,1H3
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61.7n/an/an/an/an/an/an/an/a



Università degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CA12 catalytic domain by stopped-flow CO2 hydration method


Citation and Details
More data for this
Ligand-Target Pair
Zn finger protein


(Nicotiana tabacum)
BDBM50332038
PNG
(7-hydroxy-8-acetylcoumarin | 8-Acetyl-7-hydroxy-2H...)
Show SMILES CC(=O)c1c(O)ccc2ccc(=O)oc12
Show InChI InChI=1S/C11H8O4/c1-6(12)10-8(13)4-2-7-3-5-9(14)15-11(7)10/h2-5,13H,1H3
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61.9n/an/an/an/an/an/an/an/a



Università degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CA12 catalytic domain by stopped-flow CO2 hydration method


Citation and Details
More data for this
Ligand-Target Pair
Zn finger protein


(Nicotiana tabacum)
BDBM12342
PNG
(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Show SMILES O=c1ccc2ccccc2o1
Show InChI InChI=1S/C9H6O2/c10-9-6-5-7-3-1-2-4-8(7)11-9/h1-6H
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>100n/an/an/an/an/an/an/an/a



Università degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CA12 catalytic domain by stopped-flow CO2 hydration method


Citation and Details
More data for this
Ligand-Target Pair
Zn finger protein


(Nicotiana tabacum)
BDBM50174558
PNG
(7-hydroxy-2H-1-benzopyran-2-one | 7-hydroxy-2H-chr...)
Show SMILES Oc1ccc2ccc(=O)oc2c1
Show InChI InChI=1S/C9H6O3/c10-7-3-1-6-2-4-9(11)12-8(6)5-7/h1-5,10H
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754n/an/an/an/an/an/an/an/a



Università degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CA12 catalytic domain by stopped-flow CO2 hydration method


Citation and Details
More data for this
Ligand-Target Pair
Zn finger protein


(Nicotiana tabacum)
BDBM50332039
PNG
(6-acetyl-7-methoxy-2H-chromen-2-one | CHEMBL128855...)
Show SMILES COc1cc2oc(=O)ccc2cc1C(C)=O
Show InChI InChI=1S/C12H10O4/c1-7(13)9-5-8-3-4-12(14)16-10(8)6-11(9)15-2/h3-6H,1-2H3
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6.54E+3n/an/an/an/an/an/an/an/a



Università degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CA12 catalytic domain by stopped-flow CO2 hydration method


Citation and Details
More data for this
Ligand-Target Pair
Zn finger protein


(Nicotiana tabacum)
BDBM50332023
PNG
(6-Acetyl-7-(2-adamantan-1-yl-ethoxy)-chromen-2-one...)
Show SMILES CC(=O)c1cc2ccc(=O)oc2cc1OCCC12CC3CC(CC(C3)C1)C2
Show InChI InChI=1S/C23H26O4/c1-14(24)19-9-18-2-3-22(25)27-20(18)10-21(19)26-5-4-23-11-15-6-16(12-23)8-17(7-15)13-23/h2-3,9-10,15-17H,4-8,11-13H2,1H3
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7.77E+4n/an/an/an/an/an/an/an/a



Università degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CA12 catalytic domain by stopped-flow CO2 hydration method


Citation and Details
More data for this
Ligand-Target Pair
Zn finger protein


(Nicotiana tabacum)
BDBM50332021
PNG
(6-acetyl-7-butoxy-2H-chromen-2-one | CHEMBL1288593)
Show SMILES CCCCOc1cc2oc(=O)ccc2cc1C(C)=O
Show InChI InChI=1S/C15H16O4/c1-3-4-7-18-14-9-13-11(5-6-15(17)19-13)8-12(14)10(2)16/h5-6,8-9H,3-4,7H2,1-2H3
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>1.00E+5n/an/an/an/an/an/an/an/a



Università degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CA12 catalytic domain by stopped-flow CO2 hydration method


Citation and Details
More data for this
Ligand-Target Pair
Zn finger protein


(Nicotiana tabacum)
BDBM50332036
PNG
(6-acetyl-7-propoxy-2H-chromen-2-one | CHEMBL128856...)
Show SMILES CCCOc1cc2oc(=O)ccc2cc1C(C)=O
Show InChI InChI=1S/C14H14O4/c1-3-6-17-13-8-12-10(4-5-14(16)18-12)7-11(13)9(2)15/h4-5,7-8H,3,6H2,1-2H3
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>1.00E+5n/an/an/an/an/an/an/an/a



Università degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CA12 catalytic domain by stopped-flow CO2 hydration method


Citation and Details
More data for this
Ligand-Target Pair
Zn finger protein


(Nicotiana tabacum)
BDBM50332035
PNG
(6-Acetyl-7-ethoxy-2H-chromen-2-one | CHEMBL1288559)
Show SMILES CCOc1cc2oc(=O)ccc2cc1C(C)=O
Show InChI InChI=1S/C13H12O4/c1-3-16-12-7-11-9(4-5-13(15)17-11)6-10(12)8(2)14/h4-7H,3H2,1-2H3
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>1.00E+5n/an/an/an/an/an/an/an/a



Università degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CA12 catalytic domain by stopped-flow CO2 hydration method


Citation and Details
More data for this
Ligand-Target Pair
Zn finger protein


(Nicotiana tabacum)
BDBM50332034
PNG
(7-hydroxy-6-propionyl-2H-chromen-2-one | CHEMBL128...)
Show SMILES CCC(=O)c1cc2ccc(=O)oc2cc1O
Show InChI InChI=1S/C12H10O4/c1-2-9(13)8-5-7-3-4-12(15)16-11(7)6-10(8)14/h3-6,14H,2H2,1H3
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>1.00E+5n/an/an/an/an/an/an/an/a



Università degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CA12 catalytic domain by stopped-flow CO2 hydration method


Citation and Details
More data for this
Ligand-Target Pair
Zn finger protein


(Nicotiana tabacum)
BDBM50332033
PNG
(6-Acetyl-7-hydroxy-2H-chromen-2-one | CHEMBL128853...)
Show SMILES CC(=O)c1cc2ccc(=O)oc2cc1O
Show InChI InChI=1S/C11H8O4/c1-6(12)8-4-7-2-3-11(14)15-10(7)5-9(8)13/h2-5,13H,1H3
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>1.00E+5n/an/an/an/an/an/an/an/a



Università degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CA12 catalytic domain by stopped-flow CO2 hydration method


Citation and Details
More data for this
Ligand-Target Pair
Zn finger protein


(Nicotiana tabacum)
BDBM50332022
PNG
(6-acetyl-7-(benzyloxy)-2H-chromen-2-one | CHEMBL12...)
Show SMILES CC(=O)c1cc2ccc(=O)oc2cc1OCc1ccccc1
Show InChI InChI=1S/C18H14O4/c1-12(19)15-9-14-7-8-18(20)22-16(14)10-17(15)21-11-13-5-3-2-4-6-13/h2-10H,11H2,1H3
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>1.00E+5n/an/an/an/an/an/an/an/a



Università degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CA12 catalytic domain by stopped-flow CO2 hydration method


Citation and Details
More data for this
Ligand-Target Pair