Compile Data Set for Download or QSAR

Found 82 hits Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4A'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285634 (3-(4-chloro-3,5-difluoro-phenyl)-N-cyclopropyl-imi...) Show SMILES Fc1cc(cc(F)c1Cl)-c1c(nc2cccnn12)C(=O)NC1CC1 Show InChI InChI=1S/C16H11ClF2N4O/c17-13-10(18)6-8(7-11(13)19)15-14(16(24)21-9-3-4-9)22-12-2-1-5-20-23(12)15/h1-2,5-7,9H,3-4H2,(H,21,24)	GoogleScholar AffyNet	UniChem		n/a	n/a	<0.488	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285598 (3-(3-chloro-4-methylphenyl)-N-[(1R,2S)-2-fluorocyc...) Show SMILES Cc1ccc(cc1Cl)-c1c(nc2cccnn12)C(=O)N[C@@H]1C[C@@H]1F Show InChI InChI=1S/C17H14ClFN4O/c1-9-4-5-10(7-11(9)18)16-15(17(24)21-13-8-12(13)19)22-14-3-2-6-20-23(14)16/h2-7,12-13H,8H2,1H3,(H,21,24)/t12-,13+/m0/s1	GoogleScholar AffyNet	UniChem		n/a	n/a	<0.669	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285537 (3-(4-chloro-3-fluoro-phenyl)-N-cyclopropyl-imidazo...) Show SMILES Fc1cc(ccc1Cl)-c1c(nc2cccnn12)C(=O)NC1CC1 Show InChI InChI=1S/C16H12ClFN4O/c17-11-6-3-9(8-12(11)18)15-14(16(23)20-10-4-5-10)21-13-2-1-7-19-22(13)15/h1-3,6-8,10H,4-5H2,(H,20,23)	GoogleScholar AffyNet	UniChem		n/a	n/a	1.51	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285534 (3-(4-Chloro-3-fluorophenyl)-N-(1-methyl-1H-pyrazol...) Show SMILES Cn1cc(NC(=O)c2nc3cccnn3c2-c2ccc(Cl)c(F)c2)cn1 Show InChI InChI=1S/C17H12ClFN6O/c1-24-9-11(8-21-24)22-17(26)15-16(10-4-5-12(18)13(19)7-10)25-14(23-15)3-2-6-20-25/h2-9H,1H3,(H,22,26)	GoogleScholar AffyNet	UniChem		n/a	n/a	2.77	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285572 (3-(4-chloro-3-fluorophenyl)-N-[(1R,2S)-2-fluorocyc...) Show SMILES F[C@H]1C[C@H]1NC(=O)c1nc2cccnn2c1-c1ccc(Cl)c(F)c1 Show InChI InChI=1S/C16H11ClF2N4O/c17-9-4-3-8(6-10(9)18)15-14(16(24)21-12-7-11(12)19)22-13-2-1-5-20-23(13)15/h1-6,11-12H,7H2,(H,21,24)/t11-,12+/m0/s1	GoogleScholar AffyNet	UniChem		n/a	n/a	2.91	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285568 (N-cyclopropyl-3-(3-fluoro-4-methylphenyl)imidazo[1...) Show SMILES Cc1ccc(cc1F)-c1c(nc2cccnn12)C(=O)NC1CC1 Show InChI InChI=1S/C17H15FN4O/c1-10-4-5-11(9-13(10)18)16-15(17(23)20-12-6-7-12)21-14-3-2-8-19-22(14)16/h2-5,8-9,12H,6-7H2,1H3,(H,20,23)	GoogleScholar AffyNet	UniChem		n/a	n/a	3.13	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285556 (3-(4-chloro-3-fluorophenyl)-N-propylimidazo[1,2-b]...) Show SMILES CCCNC(=O)c1nc2cccnn2c1-c1ccc(Cl)c(F)c1 Show InChI InChI=1S/C16H14ClFN4O/c1-2-7-19-16(23)14-15(10-5-6-11(17)12(18)9-10)22-13(21-14)4-3-8-20-22/h3-6,8-9H,2,7H2,1H3,(H,19,23)	GoogleScholar AffyNet	UniChem		n/a	n/a	3.48	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285536 (3-(4-Chloro-2,5-difluorophenyl)-N-cyclopropylimida...) Show SMILES Fc1cc(-c2c(nc3cccnn23)C(=O)NC2CC2)c(F)cc1Cl Show InChI InChI=1S/C16H11ClF2N4O/c17-10-7-11(18)9(6-12(10)19)15-14(16(24)21-8-3-4-8)22-13-2-1-5-20-23(13)15/h1-2,5-8H,3-4H2,(H,21,24)	GoogleScholar AffyNet	UniChem		n/a	n/a	3.83	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285576 (US10077269, Example 49 | azetidin-1-yl[3-(3-chloro...) Show SMILES Cc1ccc(cc1Cl)-c1c(nc2cccnn12)C(=O)N1CCC1 Show InChI InChI=1S/C17H15ClN4O/c1-11-5-6-12(10-13(11)18)16-15(17(23)21-8-3-9-21)20-14-4-2-7-19-22(14)16/h2,4-7,10H,3,8-9H2,1H3	GoogleScholar AffyNet	UniChem		n/a	n/a	4.16	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285626 (3-(4-chloro-2,5-difluoro-phenyl)-N-ethylimidazo[1,...) Show SMILES CCNC(=O)c1nc2cccnn2c1-c1cc(F)c(Cl)cc1F Show InChI InChI=1S/C15H11ClF2N4O/c1-2-19-15(23)13-14(22-12(21-13)4-3-5-20-22)8-6-11(18)9(16)7-10(8)17/h3-7H,2H2,1H3,(H,19,23)	GoogleScholar AffyNet	UniChem		n/a	n/a	4.58	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285551 (4-[2-(azetidin-1-ylcarbonyl)imidazo[1,2-b]pyridazi...) Show SMILES Fc1cc(-c2c(nc3cccnn23)C(=O)N2CCC2)c(F)cc1C#N Show InChI InChI=1S/C17H11F2N5O/c18-12-8-11(13(19)7-10(12)9-20)16-15(17(25)23-5-2-6-23)22-14-3-1-4-21-24(14)16/h1,3-4,7-8H,2,5-6H2	GoogleScholar AffyNet	UniChem		n/a	n/a	5.04	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285540 (US10077269, Example 13 | azetidin-1-yl[3-(4-chloro...) Show SMILES Fc1cc(ccc1Cl)-c1c(nc2cccnn12)C(=O)N1CCC1 Show InChI InChI=1S/C16H12ClFN4O/c17-11-5-4-10(9-12(11)18)15-14(16(23)21-7-2-8-21)20-13-3-1-6-19-22(13)15/h1,3-6,9H,2,7-8H2	GoogleScholar AffyNet	UniChem		n/a	n/a	5.13	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285627 (3-(4-chloro-5-fluoro-2-methylphenyl)-N-(propan-2-y...) Show SMILES CC(C)NC(=O)c1nc2cccnn2c1-c1cc(F)c(Cl)cc1C Show InChI InChI=1S/C17H16ClFN4O/c1-9(2)21-17(24)15-16(23-14(22-15)5-4-6-20-23)11-8-13(19)12(18)7-10(11)3/h4-9H,1-3H3,(H,21,24)	GoogleScholar AffyNet	UniChem		n/a	n/a	5.48	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285622 (3-(4-cyano-2,5-difluorophenyl)-N-cyclopropylimidaz...) Show SMILES Fc1cc(-c2c(nc3cccnn23)C(=O)NC2CC2)c(F)cc1C#N Show InChI InChI=1S/C17H11F2N5O/c18-12-7-11(13(19)6-9(12)8-20)16-15(17(25)22-10-3-4-10)23-14-2-1-5-21-24(14)16/h1-2,5-7,10H,3-4H2,(H,22,25)	GoogleScholar AffyNet	UniChem		n/a	n/a	5.52	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285616 (US10077269, Example 86 | azetidin-1-yl[3-(2,2-difl...) Show SMILES FC1(F)Oc2ccc(cc2O1)-c1c(nc2cccnn12)C(=O)N1CCC1 Show InChI InChI=1S/C17H12F2N4O3/c18-17(19)25-11-5-4-10(9-12(11)26-17)15-14(16(24)22-7-2-8-22)21-13-3-1-6-20-23(13)15/h1,3-6,9H,2,7-8H2	GoogleScholar AffyNet	UniChem		n/a	n/a	5.83	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285613 (US10077269, Example 83 | azetidin-1-yl[3-(3,4-dich...) Show SMILES Clc1ccc(cc1Cl)-c1c(nc2cccnn12)C(=O)N1CCC1 Show InChI InChI=1S/C16H12Cl2N4O/c17-11-5-4-10(9-12(11)18)15-14(16(23)21-7-2-8-21)20-13-3-1-6-19-22(13)15/h1,3-6,9H,2,7-8H2	GoogleScholar AffyNet	UniChem		n/a	n/a	6.21	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285547 (4-[2-(azetidin-1-ylcarbonyl)imidazo[1,2-b]pyridazi...) Show SMILES Cc1cc(C#N)c(F)cc1-c1c(nc2cccnn12)C(=O)N1CCC1 Show InChI InChI=1S/C18H14FN5O/c1-11-8-12(10-20)14(19)9-13(11)17-16(18(25)23-6-3-7-23)22-15-4-2-5-21-24(15)17/h2,4-5,8-9H,3,6-7H2,1H3	GoogleScholar AffyNet	UniChem		n/a	n/a	6.70	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285603 (US10077269, Example 76 | azetidin-1-yl{3-[2-(diflu...) Show SMILES FC(F)Oc1cc(ccn1)-c1c(nc2cccnn12)C(=O)N1CCC1 Show InChI InChI=1S/C16H13F2N5O2/c17-16(18)25-12-9-10(4-6-19-12)14-13(15(24)22-7-2-8-22)21-11-3-1-5-20-23(11)14/h1,3-6,9,16H,2,7-8H2	GoogleScholar AffyNet	UniChem		n/a	n/a	7.09	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285574 (US10077269, Example 47 | azetidin-1-yl[3-(4-chloro...) Show SMILES Fc1cc(cc(F)c1Cl)-c1c(nc2cccnn12)C(=O)N1CCC1 Show InChI InChI=1S/C16H11ClF2N4O/c17-13-10(18)7-9(8-11(13)19)15-14(16(24)22-5-2-6-22)21-12-3-1-4-20-23(12)15/h1,3-4,7-8H,2,5-6H2	GoogleScholar AffyNet	UniChem		n/a	n/a	7.37	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285611 (3-(4-chloro-3-fluorophenyl)-N-ethylimidazo[1,2-b]p...) Show SMILES CCNC(=O)c1nc2cccnn2c1-c1ccc(Cl)c(F)c1 Show InChI InChI=1S/C15H12ClFN4O/c1-2-18-15(22)13-14(9-5-6-10(16)11(17)8-9)21-12(20-13)4-3-7-19-21/h3-8H,2H2,1H3,(H,18,22)	GoogleScholar AffyNet	UniChem		n/a	n/a	7.86	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285602 (N-cyclopropyl-3-[2-(difluoro-methoxy)pyridin-4-yl]...) Show SMILES FC(F)Oc1cc(ccn1)-c1c(nc2cccnn12)C(=O)NC1CC1 Show InChI InChI=1S/C16H13F2N5O2/c17-16(18)25-12-8-9(5-7-19-12)14-13(15(24)21-10-3-4-10)22-11-2-1-6-20-23(11)14/h1-2,5-8,10,16H,3-4H2,(H,21,24)	GoogleScholar AffyNet	UniChem		n/a	n/a	10.5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285595 (3-(4-chloro-2-fluorophenyl)-N-[(1R,2S)-2-fluorocyc...) Show SMILES F[C@H]1C[C@H]1NC(=O)c1nc2cccnn2c1-c1ccc(Cl)cc1F Show InChI InChI=1S/C16H11ClF2N4O/c17-8-3-4-9(10(18)6-8)15-14(16(24)21-12-7-11(12)19)22-13-2-1-5-20-23(13)15/h1-6,11-12H,7H2,(H,21,24)/t11-,12+/m0/s1	GoogleScholar AffyNet	UniChem		n/a	n/a	10.6	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285529 (3-(4-Chlorophenyl)-N-cyclopropylimidazo[1,2-b]pyri...) Show SMILES Clc1ccc(cc1)-c1c(nc2cccnn12)C(=O)NC1CC1 Show InChI InChI=1S/C16H13ClN4O/c17-11-5-3-10(4-6-11)15-14(16(22)19-12-7-8-12)20-13-2-1-9-18-21(13)15/h1-6,9,12H,7-8H2,(H,19,22)	GoogleScholar AffyNet	UniChem		n/a	n/a	10.7	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285557 (3-(4-chlorophenyl)-N-(2-methylcyclopropyl)imidazo[...) Show SMILES CC1CC1NC(=O)c1nc2cccnn2c1-c1ccc(Cl)cc1 Show InChI InChI=1S/C17H15ClN4O/c1-10-9-13(10)20-17(23)15-16(11-4-6-12(18)7-5-11)22-14(21-15)3-2-8-19-22/h2-8,10,13H,9H2,1H3,(H,20,23)	GoogleScholar AffyNet	UniChem		n/a	n/a	11.6	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285612 (3-(4-chloro-3-fluorophenyl)-N-(1H-pyrazol-4-yl)imi...) Show SMILES Fc1cc(ccc1Cl)-c1c(nc2cccnn12)C(=O)Nc1cn[nH]c1 Show InChI	GoogleScholar AffyNet	UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285621 (US10077269, Example 91 | azetidin-1-yl[3-(4-chloro...) Show SMILES Fc1cc(-c2c(nc3cccnn23)C(=O)N2CCC2)c(F)cc1Cl Show InChI InChI=1S/C16H11ClF2N4O/c17-10-8-11(18)9(7-12(10)19)15-14(16(24)22-5-2-6-22)21-13-3-1-4-20-23(13)15/h1,3-4,7-8H,2,5-6H2	GoogleScholar AffyNet	UniChem		n/a	n/a	12.6	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285530 (Azetidin-1-yl[3-(3,5-difluoro-4-methoxyphenyl)imid...) Show SMILES COc1c(F)cc(cc1F)-c1c(nc2cccnn12)C(=O)N1CCC1 Show InChI InChI=1S/C17H14F2N4O2/c1-25-16-11(18)8-10(9-12(16)19)15-14(17(24)22-6-3-7-22)21-13-4-2-5-20-23(13)15/h2,4-5,8-9H,3,6-7H2,1H3	GoogleScholar AffyNet	UniChem		n/a	n/a	12.7	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285539 (3-(4-chloro-2-methyl-phenyl)-N-cyclopropyl-imidazo...) Show SMILES Cc1cc(Cl)ccc1-c1c(nc2cccnn12)C(=O)NC1CC1 Show InChI InChI=1S/C17H15ClN4O/c1-10-9-11(18)4-7-13(10)16-15(17(23)20-12-5-6-12)21-14-3-2-8-19-22(14)16/h2-4,7-9,12H,5-6H2,1H3,(H,20,23)	GoogleScholar AffyNet	UniChem		n/a	n/a	14.4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285566 (3-(1,3-benzoxazol-5-yl)-N-cyclopropylimidazo[1,2-b...) Show SMILES O=C(NC1CC1)c1nc2cccnn2c1-c1ccc2ocnc2c1 Show InChI InChI=1S/C17H13N5O2/c23-17(20-11-4-5-11)15-16(22-14(21-15)2-1-7-19-22)10-3-6-13-12(8-10)18-9-24-13/h1-3,6-9,11H,4-5H2,(H,20,23)	GoogleScholar AffyNet	UniChem		n/a	n/a	14.8	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285550 (4-[2-(azetidin-1-ylcarbonyl)imidazo[1,2-b]pyridazi...) Show SMILES Fc1cc(ccc1C#N)-c1c(nc2cccnn12)C(=O)N1CCC1 Show InChI InChI=1S/C17H12FN5O/c18-13-9-11(4-5-12(13)10-19)16-15(17(24)22-7-2-8-22)21-14-3-1-6-20-23(14)16/h1,3-6,9H,2,7-8H2	GoogleScholar AffyNet	UniChem		n/a	n/a	15.1	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285573 (3-(4-chlorophenyl)-N-[(1R,2S)-2-fluorocyclopro-pyl...) Show SMILES F[C@H]1C[C@H]1NC(=O)c1nc2cccnn2c1-c1ccc(Cl)cc1 Show InChI InChI=1S/C16H12ClFN4O/c17-10-5-3-9(4-6-10)15-14(16(23)20-12-8-11(12)18)21-13-2-1-7-19-22(13)15/h1-7,11-12H,8H2,(H,20,23)/t11-,12+/m0/s1	GoogleScholar AffyNet	UniChem		n/a	n/a	15.2	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285555 (3-(3,5-dichlorophenyl)-N-propylimidazo[1,2-b]pyrid...) Show SMILES CCCNC(=O)c1nc2cccnn2c1-c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C16H14Cl2N4O/c1-2-5-19-16(23)14-15(10-7-11(17)9-12(18)8-10)22-13(21-14)4-3-6-20-22/h3-4,6-9H,2,5H2,1H3,(H,19,23)	GoogleScholar AffyNet	UniChem		n/a	n/a	15.6	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285614 (US10077269, Example 84 | azetidin-1-yl[3-(3-chloro...) Show SMILES Clc1cccc(c1)-c1c(nc2cccnn12)C(=O)N1CCC1 Show InChI InChI=1S/C16H13ClN4O/c17-12-5-1-4-11(10-12)15-14(16(22)20-8-3-9-20)19-13-6-2-7-18-21(13)15/h1-2,4-7,10H,3,8-9H2	GoogleScholar AffyNet	UniChem		n/a	n/a	16.7	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285546 (3-(4-cyano-5-fluoro-2-methylphenyl)-N-cyclo-propyl...) Show SMILES Cc1cc(C#N)c(F)cc1-c1c(nc2cccnn12)C(=O)NC1CC1 Show InChI InChI=1S/C18H14FN5O/c1-10-7-11(9-20)14(19)8-13(10)17-16(18(25)22-12-4-5-12)23-15-3-2-6-21-24(15)17/h2-3,6-8,12H,4-5H2,1H3,(H,22,25)	GoogleScholar AffyNet	UniChem		n/a	n/a	16.9	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285580 (US10077269, Example 53 | azetidin-1-yl[3-(4-fluoro...) Show SMILES Cc1cc(cc(C)c1F)-c1c(nc2cccnn12)C(=O)N1CCC1 Show InChI InChI=1S/C18H17FN4O/c1-11-9-13(10-12(2)15(11)19)17-16(18(24)22-7-4-8-22)21-14-5-3-6-20-23(14)17/h3,5-6,9-10H,4,7-8H2,1-2H3	GoogleScholar AffyNet	UniChem		n/a	n/a	17.8	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285567 (3-(4-chloro-2-fluorophenyl)-N-cyclopropylimidazo[1...) Show SMILES Fc1cc(Cl)ccc1-c1c(nc2cccnn12)C(=O)NC1CC1 Show InChI InChI=1S/C16H12ClFN4O/c17-9-3-6-11(12(18)8-9)15-14(16(23)20-10-4-5-10)21-13-2-1-7-19-22(13)15/h1-3,6-8,10H,4-5H2,(H,20,23)	GoogleScholar AffyNet	UniChem		n/a	n/a	19.6	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285629 (3-(4-cyano-5-fluoro-2-methylphenyl)-N-(propan-2-yl...) Show SMILES CC(C)NC(=O)c1nc2cccnn2c1-c1cc(F)c(cc1C)C#N Show InChI InChI=1S/C18H16FN5O/c1-10(2)22-18(25)16-17(24-15(23-16)5-4-6-21-24)13-8-14(19)12(9-20)7-11(13)3/h4-8,10H,1-3H3,(H,22,25)	GoogleScholar AffyNet	UniChem		n/a	n/a	19.8	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285535 (Azetidin-1-yl[3-(pyrazolo[1,5-a]pyridin-6-yl)imida...) Show SMILES O=C(N1CCC1)c1nc2cccnn2c1-c1ccc2ccnn2c1 Show InChI InChI=1S/C17H14N6O/c24-17(21-9-2-10-21)15-16(23-14(20-15)3-1-7-19-23)12-4-5-13-6-8-18-22(13)11-12/h1,3-8,11H,2,9-10H2	GoogleScholar AffyNet	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285620 (3-(4-cyano-3-fluorophenyl)-N-cyclopropylimidazo[1,...) Show SMILES Fc1cc(ccc1C#N)-c1c(nc2cccnn12)C(=O)NC1CC1 Show InChI InChI=1S/C17H12FN5O/c18-13-8-10(3-4-11(13)9-19)16-15(17(24)21-12-5-6-12)22-14-2-1-7-20-23(14)16/h1-4,7-8,12H,5-6H2,(H,21,24)	GoogleScholar AffyNet	UniChem		n/a	n/a	21.4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285583 (US10077269, Example 56 | azetidin-1-yl[3-(4-chloro...) Show SMILES Cc1cc(Cl)ccc1-c1c(nc2cccnn12)C(=O)N1CCC1 Show InChI InChI=1S/C17H15ClN4O/c1-11-10-12(18)5-6-13(11)16-15(17(23)21-8-3-9-21)20-14-4-2-7-19-22(14)16/h2,4-7,10H,3,8-9H2,1H3	GoogleScholar AffyNet	UniChem		n/a	n/a	22.7	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285563 (3-(3-chlorophenyl)-N-cyclopropylimidazo[1,2-b]pyri...) Show SMILES Clc1cccc(c1)-c1c(nc2cccnn12)C(=O)NC1CC1 Show InChI InChI=1S/C16H13ClN4O/c17-11-4-1-3-10(9-11)15-14(16(22)19-12-6-7-12)20-13-5-2-8-18-21(13)15/h1-5,8-9,12H,6-7H2,(H,19,22)	GoogleScholar AffyNet	UniChem		n/a	n/a	23.7	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285579 (US10077269, Example 52 | azetidin-1-yl[3-(4-chloro...) Show SMILES Fc1cc(Cl)ccc1-c1c(nc2cccnn12)C(=O)N1CCC1 Show InChI InChI=1S/C16H12ClFN4O/c17-10-4-5-11(12(18)9-10)15-14(16(23)21-7-2-8-21)20-13-3-1-6-19-22(13)15/h1,3-6,9H,2,7-8H2	GoogleScholar AffyNet	UniChem		n/a	n/a	24.3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285624 (3-(4-chloro-3-fluorophenyl)-N-methylimidazo[1,2-b]...) Show SMILES CNC(=O)c1nc2cccnn2c1-c1ccc(Cl)c(F)c1 Show InChI InChI=1S/C14H10ClFN4O/c1-17-14(21)12-13(8-4-5-9(15)10(16)7-8)20-11(19-12)3-2-6-18-20/h2-7H,1H3,(H,17,21)	GoogleScholar AffyNet	UniChem		n/a	n/a	24.9	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285615 (3-(4-chlorophenyl)-N-ethylimidazo[1,2-b]pyridazine...) Show SMILES CCNC(=O)c1nc2cccnn2c1-c1ccc(Cl)cc1 Show InChI InChI=1S/C15H13ClN4O/c1-2-17-15(21)13-14(10-5-7-11(16)8-6-10)20-12(19-13)4-3-9-18-20/h3-9H,2H2,1H3,(H,17,21)	GoogleScholar AffyNet	UniChem		n/a	n/a	25.6	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285628 (3-(4-cyano-5-fluoro-2-methyl-phenyl)-N-ethylimidaz...) Show SMILES CCNC(=O)c1nc2cccnn2c1-c1cc(F)c(cc1C)C#N Show InChI InChI=1S/C17H14FN5O/c1-3-20-17(24)15-16(23-14(22-15)5-4-6-21-23)12-8-13(18)11(9-19)7-10(12)2/h4-8H,3H2,1-2H3,(H,20,24)	GoogleScholar AffyNet	UniChem		n/a	n/a	26.6	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285549 (N-cyclopropyl-3-(pyrazolo[1,5-a]pyridin-6-yl)imida...) Show SMILES O=C(NC1CC1)c1nc2cccnn2c1-c1ccc2ccnn2c1 Show InChI InChI=1S/C17H14N6O/c24-17(20-12-4-5-12)15-16(23-14(21-15)2-1-8-19-23)11-3-6-13-7-9-18-22(13)10-11/h1-3,6-10,12H,4-5H2,(H,20,24)	GoogleScholar AffyNet	UniChem		n/a	n/a	27.6	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285577 (US10077269, Example 50 | azetidin-1-yl[3-(2,3-dihy...) Show SMILES O=C(N1CCC1)c1nc2cccnn2c1-c1ccc2OCCc2c1 Show InChI InChI=1S/C18H16N4O2/c23-18(21-8-2-9-21)16-17(22-15(20-16)3-1-7-19-22)13-4-5-14-12(11-13)6-10-24-14/h1,3-5,7,11H,2,6,8-10H2	GoogleScholar AffyNet	UniChem		n/a	n/a	28.1	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285561 (3-(3-chloro-5-fluorophenyl)-N-propylimidazo[1,2-b]...) Show SMILES CCCNC(=O)c1nc2cccnn2c1-c1cc(F)cc(Cl)c1 Show InChI InChI=1S/C16H14ClFN4O/c1-2-5-19-16(23)14-15(10-7-11(17)9-12(18)8-10)22-13(21-14)4-3-6-20-22/h3-4,6-9H,2,5H2,1H3,(H,19,23)	GoogleScholar AffyNet	UniChem		n/a	n/a	29.5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285562 (3-(3-chloro-5-fluorophenyl)-N-cyclopropylimidazo[1...) Show SMILES Fc1cc(Cl)cc(c1)-c1c(nc2cccnn12)C(=O)NC1CC1 Show InChI InChI=1S/C16H12ClFN4O/c17-10-6-9(7-11(18)8-10)15-14(16(23)20-12-3-4-12)21-13-2-1-5-19-22(13)15/h1-2,5-8,12H,3-4H2,(H,20,23)	GoogleScholar AffyNet	UniChem		n/a	n/a	35.7	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3 (Homo sapiens (human))	BDBM285597 (3-(4-chloro-2-methylphenyl)-N-[(1R,2S)-2-fluorocyc...) Show SMILES Cc1cc(Cl)ccc1-c1c(nc2cccnn12)C(=O)N[C@@H]1C[C@@H]1F Show InChI InChI=1S/C17H14ClFN4O/c1-9-7-10(18)4-5-11(9)16-15(17(24)21-13-8-12(13)19)22-14-3-2-6-20-23(14)16/h2-7,12-13H,8H2,1H3,(H,21,24)/t12-,13+/m0/s1	GoogleScholar AffyNet	UniChem		n/a	n/a	36.4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				US Patent US10077269 (2018)
					More data for this Ligand-Target Pair

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