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Compile Data Set for Download or QSAR

Found 33 hits Enz. Inhib. hit(s) with Target = 'glutamate receptor, metabotropic 4 precursor' AND taxid = 10116   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
glutamate receptor, metabotropic 4 precursor


(Rattus norvegicus)
BDBM50293743
PNG
(CHEMBL556667 | N-(3-chlorophenyl)picolinamide | ci...)
Show SMILES Clc1cccc(NC(=O)c2ccccn2)c1
Show InChI InChI=1S/C12H9ClN2O/c13-9-4-3-5-10(8-9)15-12(16)11-6-1-2-7-14-11/h1-8H,(H,15,16)
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n/an/an/an/a 9.84E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

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Assay Description
Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptom...


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More data for this
Ligand-Target Pair
glutamate receptor, metabotropic 4 precursor


(Rattus norvegicus)
BDBM55089
PNG
(N-[4-[(3aS,4S,7R)-1,3-bis(oxidanylidene)-3a,4,5,6,...)
Show SMILES Oc1c2[C@H]3CC[C@H](O3)c2c(O)n1-c1ccc(NC(=O)c2ccccn2)cc1Cl
Show InChI InChI=1S/C20H16ClN3O4/c21-11-9-10(23-18(25)12-3-1-2-8-22-12)4-5-13(11)24-19(26)16-14-6-7-15(28-14)17(16)20(24)27/h1-5,8-9,14-15,26-27H,6-7H2,(H,23,25)/t14-,15+
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n/an/an/an/a 2.29E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

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Assay Description
Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...


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More data for this
Ligand-Target Pair
glutamate receptor, metabotropic 4 precursor


(Rattus norvegicus)
BDBM50293734
PNG
(CHEMBL560021 | N-(3,4-dichlorophenyl)pyrimidine-4-...)
Show SMILES Clc1ccc(NC(=O)c2ccncn2)cc1Cl
Show InChI InChI=1S/C11H7Cl2N3O/c12-8-2-1-7(5-9(8)13)16-11(17)10-3-4-14-6-15-10/h1-6H,(H,16,17)
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n/an/an/an/a 3.37E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

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Assay Description
Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...


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More data for this
Ligand-Target Pair
glutamate receptor, metabotropic 4 precursor


(Rattus norvegicus)
BDBM50293729
PNG
(CHEMBL557685 | N-(3,4-dichlorophenyl)thiophene-3-c...)
Show SMILES Clc1ccc(NC(=O)c2ccsc2)cc1Cl
Show InChI InChI=1S/C11H7Cl2NOS/c12-9-2-1-8(5-10(9)13)14-11(15)7-3-4-16-6-7/h1-6H,(H,14,15)
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n/an/an/an/a 9.23E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

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Assay Description
Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...


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More data for this
Ligand-Target Pair
glutamate receptor, metabotropic 4 precursor


(Rattus norvegicus)
BDBM50293728
PNG
(CHEMBL538868 | N-(3,4-dichlorophenyl)isoxazole-5-c...)
Show SMILES Clc1ccc(NC(=O)c2ccno2)cc1Cl
Show InChI InChI=1S/C10H6Cl2N2O2/c11-7-2-1-6(5-8(7)12)14-10(15)9-3-4-13-16-9/h1-5H,(H,14,15)
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n/an/an/an/a 1.11E+4n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

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Assay Description
Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...


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More data for this
Ligand-Target Pair
glutamate receptor, metabotropic 4 precursor


(Rattus norvegicus)
BDBM50293732
PNG
(CHEMBL549330 | N-(3,4-dichlorophenyl)picolinamide ...)
Show SMILES Clc1ccc(NC(=O)c2ccccn2)cc1Cl
Show InChI InChI=1S/C12H8Cl2N2O/c13-9-5-4-8(7-10(9)14)16-12(17)11-3-1-2-6-15-11/h1-7H,(H,16,17)
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n/an/an/an/a 1.25E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

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Assay Description
Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...


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More data for this
Ligand-Target Pair
glutamate receptor, metabotropic 4 precursor


(Rattus norvegicus)
BDBM50293721
PNG
(CHEMBL562551 | N-(4-chloro-3-methoxyphenyl)picolin...)
Show SMILES COc1cc(NC(=O)c2ccccn2)ccc1Cl
Show InChI InChI=1S/C13H11ClN2O2/c1-18-12-8-9(5-6-10(12)14)16-13(17)11-4-2-3-7-15-11/h2-8H,1H3,(H,16,17)
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n/an/an/an/a 107n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

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Assay Description
Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...


Citation and Details
More data for this
Ligand-Target Pair
glutamate receptor, metabotropic 4 precursor


(Rattus norvegicus)
BDBM50293714
PNG
(CHEMBL551635 | N-(4-fluoro-3-methoxyphenyl)picolin...)
Show SMILES COc1cc(NC(=O)c2ccccn2)ccc1F
Show InChI InChI=1S/C13H11FN2O2/c1-18-12-8-9(5-6-10(12)14)16-13(17)11-4-2-3-7-15-11/h2-8H,1H3,(H,16,17)
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Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

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Assay Description
Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...


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More data for this
Ligand-Target Pair
glutamate receptor, metabotropic 4 precursor


(Rattus norvegicus)
BDBM50293719
PNG
(CHEMBL571453 | N-(3-(trifluoromethyl)phenyl)picoli...)
Show SMILES FC(F)(F)c1cccc(NC(=O)c2ccccn2)c1
Show InChI InChI=1S/C13H9F3N2O/c14-13(15,16)9-4-3-5-10(8-9)18-12(19)11-6-1-2-7-17-11/h1-8H,(H,18,19)
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Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

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Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...


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More data for this
Ligand-Target Pair
glutamate receptor, metabotropic 4 precursor


(Rattus norvegicus)
BDBM50293722
PNG
(CHEMBL559271 | N-(3-(trifluoromethoxy)phenyl)picol...)
Show SMILES FC(F)(F)Oc1cccc(NC(=O)c2ccccn2)c1
Show InChI InChI=1S/C13H9F3N2O2/c14-13(15,16)20-10-5-3-4-9(8-10)18-12(19)11-6-1-2-7-17-11/h1-8H,(H,18,19)
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n/an/an/an/a 3.07E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

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Assay Description
Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...


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More data for this
Ligand-Target Pair
glutamate receptor, metabotropic 4 precursor


(Rattus norvegicus)
BDBM50293720
PNG
(CHEMBL541754 | N-(3-(difluoromethoxy)phenyl)picoli...)
Show SMILES FC(F)Oc1cccc(NC(=O)c2ccccn2)c1
Show InChI InChI=1S/C13H10F2N2O2/c14-13(15)19-10-5-3-4-9(8-10)17-12(18)11-6-1-2-7-16-11/h1-8,13H,(H,17,18)
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n/an/an/an/a 78.3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

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Assay Description
Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...


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More data for this
Ligand-Target Pair
glutamate receptor, metabotropic 4 precursor


(Rattus norvegicus)
BDBM50293718
PNG
(CHEMBL561835 | N-(3-methoxy-4-methylphenyl)picolin...)
Show SMILES COc1cc(NC(=O)c2ccccn2)ccc1C
Show InChI InChI=1S/C14H14N2O2/c1-10-6-7-11(9-13(10)18-2)16-14(17)12-5-3-4-8-15-12/h3-9H,1-2H3,(H,16,17)
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Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

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Assay Description
Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...


Citation and Details
More data for this
Ligand-Target Pair
glutamate receptor, metabotropic 4 precursor


(Rattus norvegicus)
BDBM50293717
PNG
(CHEMBL572346 | N-(3,4-dimethoxyphenyl)picolinamide...)
Show SMILES COc1ccc(NC(=O)c2ccccn2)cc1OC
Show InChI InChI=1S/C14H14N2O3/c1-18-12-7-6-10(9-13(12)19-2)16-14(17)11-5-3-4-8-15-11/h3-9H,1-2H3,(H,16,17)
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n/an/an/an/a 2.35E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

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Assay Description
Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...


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More data for this
Ligand-Target Pair
glutamate receptor, metabotropic 4 precursor


(Rattus norvegicus)
BDBM50293715
PNG
(CHEMBL562036 | N-(benzo[d][1,3]dioxol-5-yl)picolin...)
Show SMILES O=C(Nc1ccc2OCOc2c1)c1ccccn1
Show InChI InChI=1S/C13H10N2O3/c16-13(10-3-1-2-6-14-10)15-9-4-5-11-12(7-9)18-8-17-11/h1-7H,8H2,(H,15,16)
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n/an/an/an/a 7.17E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

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Assay Description
Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...


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More data for this
Ligand-Target Pair
glutamate receptor, metabotropic 4 precursor


(Rattus norvegicus)
BDBM50293716
PNG
(CHEMBL562232 | N-(3-chloro-4-methoxyphenyl)picolin...)
Show SMILES COc1ccc(NC(=O)c2ccccn2)cc1Cl
Show InChI InChI=1S/C13H11ClN2O2/c1-18-12-6-5-9(8-10(12)14)16-13(17)11-4-2-3-7-15-11/h2-8H,1H3,(H,16,17)
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Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

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Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...


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Ligand-Target Pair
glutamate receptor, metabotropic 4 precursor


(Rattus norvegicus)
BDBM50293741
PNG
(CHEMBL563423 | N-(4-chloro-3-(trifluoromethyl)phen...)
Show SMILES FC(F)(F)c1cc(NC(=O)c2ccccn2)ccc1Cl
Show InChI InChI=1S/C13H8ClF3N2O/c14-10-5-4-8(7-9(10)13(15,16)17)19-12(20)11-3-1-2-6-18-11/h1-7H,(H,19,20)
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n/an/an/an/a 1.71E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

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Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...


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Ligand-Target Pair
glutamate receptor, metabotropic 4 precursor


(Rattus norvegicus)
BDBM50293739
PNG
(CHEMBL555454 | N-(4-fluoro-3-(trifluoromethyl)phen...)
Show SMILES Fc1ccc(NC(=O)c2ccccn2)cc1C(F)(F)F
Show InChI InChI=1S/C13H8F4N2O/c14-10-5-4-8(7-9(10)13(15,16)17)19-12(20)11-3-1-2-6-18-11/h1-7H,(H,19,20)
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Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

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Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...


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More data for this
Ligand-Target Pair
glutamate receptor, metabotropic 4 precursor


(Rattus norvegicus)
BDBM50293743
PNG
(CHEMBL556667 | N-(3-chlorophenyl)picolinamide | ci...)
Show SMILES Clc1cccc(NC(=O)c2ccccn2)c1
Show InChI InChI=1S/C12H9ClN2O/c13-9-4-3-5-10(8-9)15-12(16)11-6-1-2-7-14-11/h1-8H,(H,15,16)
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Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

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Assay Description
Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...


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Ligand-Target Pair
glutamate receptor, metabotropic 4 precursor


(Rattus norvegicus)
BDBM55082
PNG
(N-[4-[(2-chlorobenzoyl)amino]-3-methoxy-phenyl]pic...)
Show SMILES COc1cc(NC(=O)c2ccccn2)ccc1NC(=O)c1ccccc1Cl
Show InChI InChI=1S/C20H16ClN3O3/c1-27-18-12-13(23-20(26)17-8-4-5-11-22-17)9-10-16(18)24-19(25)14-6-2-3-7-15(14)21/h2-12H,1H3,(H,23,26)(H,24,25)
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Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

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Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...


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Ligand-Target Pair
glutamate receptor, metabotropic 4 precursor


(Rattus norvegicus)
BDBM55081
PNG
(ML182 | VU0400195-3 | cid_46869947)
Show SMILES Clc1cc(NC(=O)c2ccccn2)ccc1N1C(=O)C2[C@@H]3C[C@@H](C=C3)[C@H]2C1=O
Show InChI InChI=1S/C21H16ClN3O3/c22-14-10-13(24-19(26)15-3-1-2-8-23-15)6-7-16(14)25-20(27)17-11-4-5-12(9-11)18(17)21(25)28/h1-8,10-12,17-18H,9H2,(H,24,26)/t11-,12+,17-,18?/m1/s1
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Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

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Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...


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Ligand-Target Pair
glutamate receptor, metabotropic 4 precursor


(Rattus norvegicus)
BDBM55090
PNG
(VU0404304-2 | cid_46869948)
Show SMILES Clc1cc(NC(=O)c2ccccn2)ccc1N1C(=O)C2[C@@H]([C@@H]3CC[C@H]2C=C3)C1=O
Show InChI InChI=1S/C22H18ClN3O3/c23-15-11-14(25-20(27)16-3-1-2-10-24-16)8-9-17(15)26-21(28)18-12-4-5-13(7-6-12)19(18)22(26)29/h1-5,8-13,18-19H,6-7H2,(H,25,27)/t12-,13+,18+,19?/m0/s1
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Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

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Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...


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Ligand-Target Pair
glutamate receptor, metabotropic 4 precursor


(Rattus norvegicus)
BDBM55091
PNG
(N-[3-chloranyl-4-[(1S,5R)-6,6-dimethyl-2,4-bis(oxi...)
Show SMILES CC1(C)c2c1c(O)n(c2O)-c1ccc(NC(=O)c2ccccn2)cc1Cl
Show InChI InChI=1S/C19H16ClN3O3/c1-19(2)14-15(19)18(26)23(17(14)25)13-7-6-10(9-11(13)20)22-16(24)12-5-3-4-8-21-12/h3-9,25-26H,1-2H3,(H,22,24)
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n/an/an/an/a 690n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

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Assay Description
Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...


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More data for this
Ligand-Target Pair
glutamate receptor, metabotropic 4 precursor


(Rattus norvegicus)
BDBM55092
PNG
(N-[3-chloranyl-4-[3,3-dimethyl-2,5-bis(oxidanylide...)
Show SMILES CC1(C)CC(=O)N(C1=O)c1ccc(NC(=O)c2ccccn2)cc1Cl
Show InChI InChI=1S/C18H16ClN3O3/c1-18(2)10-15(23)22(17(18)25)14-7-6-11(9-12(14)19)21-16(24)13-5-3-4-8-20-13/h3-9H,10H2,1-2H3,(H,21,24)
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n/an/an/an/a 2.32E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

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Assay Description
Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...


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Ligand-Target Pair
glutamate receptor, metabotropic 4 precursor


(Rattus norvegicus)
BDBM55093
PNG
(N-[3-chloro-4-(1,3-diketo-2-azaspiro[4.5]decan-2-y...)
Show SMILES Clc1cc(NC(=O)c2ccccn2)ccc1N1C(=O)CC2(CCCCC2)C1=O
Show InChI InChI=1S/C21H20ClN3O3/c22-15-12-14(24-19(27)16-6-2-5-11-23-16)7-8-17(15)25-18(26)13-21(20(25)28)9-3-1-4-10-21/h2,5-8,11-12H,1,3-4,9-10,13H2,(H,24,27)
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Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

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Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...


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More data for this
Ligand-Target Pair
glutamate receptor, metabotropic 4 precursor


(Rattus norvegicus)
BDBM55094
PNG
(N-[3-chloro-4-(2,5-diketo-3-phenyl-pyrrolidino)phe...)
Show SMILES Oc1cc(c(O)n1-c1ccc(NC(=O)c2ccccn2)cc1Cl)-c1ccccc1
Show InChI InChI=1S/C22H16ClN3O3/c23-17-12-15(25-21(28)18-8-4-5-11-24-18)9-10-19(17)26-20(27)13-16(22(26)29)14-6-2-1-3-7-14/h1-13,27,29H,(H,25,28)
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Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...


Citation and Details
More data for this
Ligand-Target Pair
glutamate receptor, metabotropic 4 precursor


(Rattus norvegicus)
BDBM55095
PNG
(N-[3-chloranyl-4-[3-methyl-2,5-bis(oxidanylidene)-...)
Show SMILES CC1(CC(=O)N(C1=O)c1ccc(NC(=O)c2ccccn2)cc1Cl)c1ccccc1
Show InChI InChI=1S/C23H18ClN3O3/c1-23(15-7-3-2-4-8-15)14-20(28)27(22(23)30)19-11-10-16(13-17(19)24)26-21(29)18-9-5-6-12-25-18/h2-13H,14H2,1H3,(H,26,29)
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n/an/an/an/a 540n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...


Citation and Details
More data for this
Ligand-Target Pair
glutamate receptor, metabotropic 4 precursor


(Rattus norvegicus)
BDBM55083
PNG
(N-[3-chloranyl-4-[(2-chlorophenyl)carbonylamino]ph...)
Show SMILES Clc1ccccc1C(=O)Nc1ccc(NC(=O)c2ccccn2)cc1Cl
Show InChI InChI=1S/C19H13Cl2N3O2/c20-14-6-2-1-5-13(14)18(25)24-16-9-8-12(11-15(16)21)23-19(26)17-7-3-4-10-22-17/h1-11H,(H,23,26)(H,24,25)
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Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...


Citation and Details
More data for this
Ligand-Target Pair
glutamate receptor, metabotropic 4 precursor


(Rattus norvegicus)
BDBM55084
PNG
(N-[4-[(2-chlorobenzoyl)amino]-3-fluoro-phenyl]pico...)
Show SMILES Fc1cc(NC(=O)c2ccccn2)ccc1NC(=O)c1ccccc1Cl
Show InChI InChI=1S/C19H13ClFN3O2/c20-14-6-2-1-5-13(14)18(25)24-16-9-8-12(11-15(16)21)23-19(26)17-7-3-4-10-22-17/h1-11H,(H,23,26)(H,24,25)
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Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...


Citation and Details
More data for this
Ligand-Target Pair
glutamate receptor, metabotropic 4 precursor


(Rattus norvegicus)
BDBM55085
PNG
(N-(3-chloro-4-succinimido-phenyl)picolinamide | N-...)
Show SMILES Oc1ccc(O)n1-c1ccc(NC(=O)c2ccccn2)cc1Cl
Show InChI InChI=1S/C16H12ClN3O3/c17-11-9-10(19-16(23)12-3-1-2-8-18-12)4-5-13(11)20-14(21)6-7-15(20)22/h1-9,21-22H,(H,19,23)
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Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...


Citation and Details
More data for this
Ligand-Target Pair
glutamate receptor, metabotropic 4 precursor


(Rattus norvegicus)
BDBM55086
PNG
(N-(3-chloro-4-phthalimido-phenyl)picolinamide | N-...)
Show SMILES Clc1cc(NC(=O)c2ccccn2)ccc1N1C(=O)c2ccccc2C1=O
Show InChI InChI=1S/C20H12ClN3O3/c21-15-11-12(23-18(25)16-7-3-4-10-22-16)8-9-17(15)24-19(26)13-5-1-2-6-14(13)20(24)27/h1-11H,(H,23,25)
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Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...


Citation and Details
More data for this
Ligand-Target Pair
glutamate receptor, metabotropic 4 precursor


(Rattus norvegicus)
BDBM55087
PNG
(N-[3-chloranyl-4-[4-chloranyl-1,3-bis(oxidanyliden...)
Show SMILES Clc1cccc2C(=O)N(C(=O)c12)c1ccc(NC(=O)c2ccccn2)cc1Cl
Show InChI InChI=1S/C20H11Cl2N3O3/c21-13-5-3-4-12-17(13)20(28)25(19(12)27)16-8-7-11(10-14(16)22)24-18(26)15-6-1-2-9-23-15/h1-10H,(H,24,26)
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Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...


Citation and Details
More data for this
Ligand-Target Pair
glutamate receptor, metabotropic 4 precursor


(Rattus norvegicus)
BDBM55088
PNG
(N-[4-[(7aS)-1,3-bis(oxidanylidene)-3a,4,5,6,7,7a-h...)
Show SMILES Oc1c2CCCCc2c(O)n1-c1ccc(NC(=O)c2ccccn2)cc1Cl
Show InChI InChI=1S/C20H18ClN3O3/c21-15-11-12(23-18(25)16-7-3-4-10-22-16)8-9-17(15)24-19(26)13-5-1-2-6-14(13)20(24)27/h3-4,7-11,26-27H,1-2,5-6H2,(H,23,25)
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Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...


Citation and Details
More data for this
Ligand-Target Pair
glutamate receptor, metabotropic 4 precursor


(Rattus norvegicus)
BDBM50293723
PNG
(CHEMBL551004 | N-(3,4-dichlorophenyl)furan-2-carbo...)
Show SMILES Clc1ccc(NC(=O)c2ccco2)cc1Cl
Show InChI InChI=1S/C11H7Cl2NO2/c12-8-4-3-7(6-9(8)13)14-11(15)10-2-1-5-16-10/h1-6H,(H,14,15)
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n/an/an/an/a 3.58E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...


Citation and Details
More data for this
Ligand-Target Pair