Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
MAP kinase-interacting serine/threonine-protein kinase 1/2 (Homo sapiens (Human)) | BDBM400829![]() (6'-((1,2,5-thiadiazol-3-yl)amino)-8'-chloro-2'H-sp...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
eFFECTOR Therapeutics Inc US Patent | Assay Description Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re... | US Patent US10000487 (2018) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KP84H6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase-interacting serine/threonine-protein kinase 1/2 (Homo sapiens (Human)) | BDBM400830![]() (8'-chloro-6'-((2-methyl-2H-1,2,3-triazol-4-yl)amin...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
eFFECTOR Therapeutics Inc US Patent | Assay Description Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re... | US Patent US10000487 (2018) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KP84H6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase-interacting serine/threonine-protein kinase 1/2 (Homo sapiens (Human)) | BDBM400834![]() (6'-((1,3,5-triazin-2-yl)amino)-8'-chloro-2'H-spiro...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
eFFECTOR Therapeutics Inc US Patent | Assay Description Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re... | US Patent US10000487 (2018) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KP84H6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase-interacting serine/threonine-protein kinase 1/2 (Homo sapiens (Human)) | BDBM400811![]() (US10000487, Example 2F) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
eFFECTOR Therapeutics Inc US Patent | Assay Description Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re... | US Patent US10000487 (2018) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KP84H6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase-interacting serine/threonine-protein kinase 1/2 (Homo sapiens (Human)) | BDBM400832![]() (6'-((2H-1,2,3-triazol-4-yl)amino)-8'-chloro-2'H-sp...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
eFFECTOR Therapeutics Inc US Patent | Assay Description Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re... | US Patent US10000487 (2018) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KP84H6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human)) | BDBM400832![]() (6'-((2H-1,2,3-triazol-4-yl)amino)-8'-chloro-2'H-sp...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article US Patent | n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
eFFECTOR Therapeutics Inc US Patent | Assay Description Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re... | US Patent US10000487 (2018) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KP84H6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase-interacting serine/threonine-protein kinase 1/2 (Homo sapiens (Human)) | BDBM400836![]() (6'-((2-aminopyridin-4-yl)amino)-8'-chloro-2'H-spir...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article US Patent | n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
eFFECTOR Therapeutics Inc US Patent | Assay Description Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re... | US Patent US10000487 (2018) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KP84H6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human)) | BDBM400811![]() (US10000487, Example 2F) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article US Patent | n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
eFFECTOR Therapeutics Inc US Patent | Assay Description Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re... | US Patent US10000487 (2018) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KP84H6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase-interacting serine/threonine-protein kinase 1/2 (Homo sapiens (Human)) | BDBM400828![]() (8'-chloro-6'-(thiazol-5-ylamino)-2'H-spiro[cyclohe...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article US Patent | n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
eFFECTOR Therapeutics Inc US Patent | Assay Description Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re... | US Patent US10000487 (2018) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KP84H6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase-interacting serine/threonine-protein kinase 1/2 (Homo sapiens (Human)) | BDBM400827![]() (US10000487, Example 4F) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article US Patent | n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
eFFECTOR Therapeutics Inc US Patent | Assay Description Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re... | US Patent US10000487 (2018) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KP84H6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase-interacting serine/threonine-protein kinase 1/2 (Homo sapiens (Human)) | BDBM400805![]() (US10000487, Example 1F) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article US Patent | n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
eFFECTOR Therapeutics Inc US Patent | Assay Description Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re... | US Patent US10000487 (2018) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KP84H6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase-interacting serine/threonine-protein kinase 1/2 (Homo sapiens (Human)) | BDBM400835![]() (6'-((1,2,4-triazin-3-yl)amino)-8'-chloro-2'H-spiro...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article US Patent | n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
eFFECTOR Therapeutics Inc US Patent | Assay Description Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re... | US Patent US10000487 (2018) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KP84H6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase-interacting serine/threonine-protein kinase 1/2 (Homo sapiens (Human)) | BDBM400833![]() (6'-((1,2,4-triazin-3-yl)amino)-8'-chloro-2'H-spiro...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article US Patent | n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
eFFECTOR Therapeutics Inc US Patent | Assay Description Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re... | US Patent US10000487 (2018) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KP84H6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase-interacting serine/threonine-protein kinase 1/2 (Homo sapiens (Human)) | BDBM400826![]() (6'-((1,2,3-thiadiazol-5-yl)amino)-8'-chloro-2'H-sp...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article US Patent | n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
eFFECTOR Therapeutics Inc US Patent | Assay Description Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re... | US Patent US10000487 (2018) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KP84H6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human)) | BDBM400827![]() (US10000487, Example 4F) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article US Patent | n/a | n/a | >5.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
eFFECTOR Therapeutics Inc US Patent | Assay Description Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re... | US Patent US10000487 (2018) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KP84H6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase-interacting serine/threonine-protein kinase 1/2 (Homo sapiens (Human)) | BDBM400831![]() (6'-((1,3,4-oxadiazol-2-yl)amino)-8'-chloro-2'H-spi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article US Patent | n/a | n/a | >5.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
eFFECTOR Therapeutics Inc US Patent | Assay Description Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re... | US Patent US10000487 (2018) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KP84H6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human)) | BDBM400828![]() (8'-chloro-6'-(thiazol-5-ylamino)-2'H-spiro[cyclohe...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article US Patent | n/a | n/a | >5.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
eFFECTOR Therapeutics Inc US Patent | Assay Description Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re... | US Patent US10000487 (2018) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KP84H6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human)) | BDBM400831![]() (6'-((1,3,4-oxadiazol-2-yl)amino)-8'-chloro-2'H-spi...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article US Patent | n/a | n/a | >5.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
eFFECTOR Therapeutics Inc US Patent | Assay Description Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re... | US Patent US10000487 (2018) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KP84H6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human)) | BDBM400805![]() (US10000487, Example 1F) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article US Patent | n/a | n/a | >5.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
eFFECTOR Therapeutics Inc US Patent | Assay Description Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re... | US Patent US10000487 (2018) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KP84H6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human)) | BDBM400835![]() (6'-((1,2,4-triazin-3-yl)amino)-8'-chloro-2'H-spiro...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article US Patent | n/a | n/a | >1.00E+7 | n/a | n/a | n/a | n/a | n/a | n/a |
eFFECTOR Therapeutics Inc US Patent | Assay Description Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re... | US Patent US10000487 (2018) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KP84H6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human)) | BDBM400826![]() (6'-((1,2,3-thiadiazol-5-yl)amino)-8'-chloro-2'H-sp...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article US Patent | n/a | n/a | >1.00E+7 | n/a | n/a | n/a | n/a | n/a | n/a |
eFFECTOR Therapeutics Inc US Patent | Assay Description Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re... | US Patent US10000487 (2018) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KP84H6 | |||||||||||
More data for this Ligand-Target Pair |