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Found 18 Enz. Inhib. hit(s) with all data for entry = 3512
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Youngene Therapeutics

US Patent
LigandPNGBDBM402285(US10011627, 1)
Affinity DataIC50:  0.580nMAssay Description:The following method was used to determine the inhibitory activity of the compounds of the present invention on SGLT1 and SGLT2. The experimental met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Youngene Therapeutics

US Patent
LigandPNGBDBM402292(US10011627, 8)
Affinity DataIC50:  1.21nMAssay Description:The following method was used to determine the inhibitory activity of the compounds of the present invention on SGLT1 and SGLT2. The experimental met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Youngene Therapeutics

US Patent
LigandPNGBDBM402293(US10011627, 9)
Affinity DataIC50:  1.49nMAssay Description:The following method was used to determine the inhibitory activity of the compounds of the present invention on SGLT1 and SGLT2. The experimental met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Youngene Therapeutics

US Patent
LigandPNGBDBM402291(US10011627, 7)
Affinity DataIC50:  1.82nMAssay Description:The following method was used to determine the inhibitory activity of the compounds of the present invention on SGLT1 and SGLT2. The experimental met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Youngene Therapeutics

US Patent
LigandPNGBDBM402290(US10011627, 6)
Affinity DataIC50:  2.59nMAssay Description:The following method was used to determine the inhibitory activity of the compounds of the present invention on SGLT1 and SGLT2. The experimental met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Youngene Therapeutics

US Patent
LigandPNGBDBM402286(US10011627, 2)
Affinity DataIC50:  3.67nMAssay Description:The following method was used to determine the inhibitory activity of the compounds of the present invention on SGLT1 and SGLT2. The experimental met...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Youngene Therapeutics

US Patent
LigandPNGBDBM402289(US10011627, 5)
Affinity DataIC50:  4.30nMAssay Description:The following method was used to determine the inhibitory activity of the compounds of the present invention on SGLT1 and SGLT2. The experimental met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Youngene Therapeutics

US Patent
LigandPNGBDBM402286(US10011627, 2)
Affinity DataIC50:  15.7nMAssay Description:The following method was used to determine the inhibitory activity of the compounds of the present invention on SGLT1 and SGLT2. The experimental met...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Youngene Therapeutics

US Patent
LigandPNGBDBM402293(US10011627, 9)
Affinity DataIC50:  16.6nMAssay Description:The following method was used to determine the inhibitory activity of the compounds of the present invention on SGLT1 and SGLT2. The experimental met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Youngene Therapeutics

US Patent
LigandPNGBDBM402291(US10011627, 7)
Affinity DataIC50:  17.2nMAssay Description:The following method was used to determine the inhibitory activity of the compounds of the present invention on SGLT1 and SGLT2. The experimental met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Youngene Therapeutics

US Patent
LigandPNGBDBM402287(US10011627, 3)
Affinity DataIC50:  19.8nMAssay Description:The following method was used to determine the inhibitory activity of the compounds of the present invention on SGLT1 and SGLT2. The experimental met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Youngene Therapeutics

US Patent
LigandPNGBDBM402288(US10011627, 4)
Affinity DataIC50:  89nMAssay Description:The following method was used to determine the inhibitory activity of the compounds of the present invention on SGLT1 and SGLT2. The experimental met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Youngene Therapeutics

US Patent
LigandPNGBDBM402290(US10011627, 6)
Affinity DataIC50:  99.9nMAssay Description:The following method was used to determine the inhibitory activity of the compounds of the present invention on SGLT1 and SGLT2. The experimental met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Youngene Therapeutics

US Patent
LigandPNGBDBM402288(US10011627, 4)
Affinity DataIC50:  132nMAssay Description:The following method was used to determine the inhibitory activity of the compounds of the present invention on SGLT1 and SGLT2. The experimental met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Youngene Therapeutics

US Patent
LigandPNGBDBM402289(US10011627, 5)
Affinity DataIC50:  301nMAssay Description:The following method was used to determine the inhibitory activity of the compounds of the present invention on SGLT1 and SGLT2. The experimental met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Youngene Therapeutics

US Patent
LigandPNGBDBM402292(US10011627, 8)
Affinity DataIC50:  583nMAssay Description:The following method was used to determine the inhibitory activity of the compounds of the present invention on SGLT1 and SGLT2. The experimental met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Youngene Therapeutics

US Patent
LigandPNGBDBM402285(US10011627, 1)
Affinity DataIC50:  953nMAssay Description:The following method was used to determine the inhibitory activity of the compounds of the present invention on SGLT1 and SGLT2. The experimental met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Youngene Therapeutics

US Patent
LigandPNGBDBM402287(US10011627, 3)
Affinity DataIC50:  2.56E+3nMAssay Description:The following method was used to determine the inhibitory activity of the compounds of the present invention on SGLT1 and SGLT2. The experimental met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent