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Patent code US10022387

Compile Data Set for Download or QSAR
Found 157 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281549
PNG
(N-(5-(2-(1H-Benzo[d]imidazol-2- yl)benzo[d]oxazol-...)
Show SMILES Fc1ncc(cc1NS(=O)(=O)CC(F)(F)F)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
MMDB

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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281553
PNG
(N-(5-(2-(1H-Benzo[d]imidazol-2- yl)benzo[d]oxazol-...)
Show SMILES CCS(=O)(=O)Nc1cc(cnc1OC)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
MMDB

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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281496
PNG
(N'-{5-[2-(1H- Benzimidazol-2- yl)-1,3- benzoxazol-...)
Show SMILES CN(C)S(=O)(=O)Nc1cc(cnc1C)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
MMDB

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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281510
PNG
(US10022387, Example 36)
Show SMILES CS(=O)(=O)c1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
MMDB

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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281527
PNG
(US10022387, Example 53 | US10022387, Example 54)
Show SMILES CCn1cc2ccc(cc2n1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
MMDB

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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281527
PNG
(US10022387, Example 53 | US10022387, Example 54)
Show SMILES CCn1cc2ccc(cc2n1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
MMDB

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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281535
PNG
(US10022387, Example 61)
Show SMILES OC(c1cncc(c1)-c1ccc2nc(oc2c1)-c1ncc[nH]1)C(F)(F)F
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281539
PNG
(US10022387, Example 65)
Show SMILES CCS(=O)(=O)Nc1cc(cnc1OC)-c1ccc2nc(oc2c1)-c1nc(C)c(C)[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281540
PNG
(US10022387, Example 66)
Show SMILES CCS(=O)(=O)Nc1cc(cnc1OC)-c1ccc2nc(oc2c1)-c1nc2CCCCc2[nH]1
PDB
MMDB

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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281543
PNG
(2-(1H-Benzo[d]imidazol-2-yl)-6-(6- fluoro-5-methox...)
Show SMILES CCc1cc(cnc1F)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
MMDB

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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281546
PNG
(2-(1H-Benzo[d]imidazol-2-yl)-6-(5- (dimethylphosph...)
Show SMILES CP(C)(=O)c1cc(cnc1F)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
MMDB

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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281486
PNG
(US10022387, Example 12)
Show SMILES COc1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2c(C)cccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281492
PNG
(N-(5-(2-(1H- Benzo[d]imidazol- 2- yl)benzo[d]oxazo...)
Show SMILES CCS(=O)(=O)Nc1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
MMDB

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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281496
PNG
(N'-{5-[2-(1H- Benzimidazol-2- yl)-1,3- benzoxazol-...)
Show SMILES CN(C)S(=O)(=O)Nc1cc(cnc1C)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
MMDB

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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281508
PNG
(US10022387, Example 34)
Show SMILES CN(C)c1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
MMDB

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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281530
PNG
(US10022387, Example 56)
Show SMILES Nc1ncc(cc1C(F)(F)F)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
MMDB

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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281535
PNG
(US10022387, Example 61)
Show SMILES OC(c1cncc(c1)-c1ccc2nc(oc2c1)-c1ncc[nH]1)C(F)(F)F
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281492
PNG
(N-(5-(2-(1H- Benzo[d]imidazol- 2- yl)benzo[d]oxazo...)
Show SMILES CCS(=O)(=O)Nc1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
MMDB

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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281490
PNG
(US10022387, Example 16)
Show SMILES FC(F)Oc1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281491
PNG
(US10022387, Example 17)
Show SMILES Fc1ccc(cc1)S(=O)(=O)Nc1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281502
PNG
(N-(5-(2-(1H- Benzo[d]imdiazol- 2 - yl)benzo[d]oxaz...)
Show SMILES Cc1ncc(cc1NS(=O)(=O)c1ccc(F)cc1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281505
PNG
(N-(5-(2-(1H- Benzo[d]imidazol- 2- yl)benzo[d]oxazo...)
Show SMILES CN1CCN(CC1)S(=O)(=O)Nc1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281513
PNG
(US10022387, Example 39)
Show SMILES Fc1ccc(cc1)S(=O)(=O)Nc1cncc(c1)-c1ccc2nc(oc2c1)-c1ncc[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281526
PNG
(US10022387, Example 52)
Show SMILES CCS(=O)(=O)n1ncc2ccc(cc12)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281538
PNG
(US10022387, Example 64)
Show SMILES CCCc1nc([nH]c1C)-c1nc2ccc(cc2o1)-c1cncc(NS(=O)(=O)CC)c1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281542
PNG
(US10022387, Example 68)
Show SMILES OC(c1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2CCCCc2[nH]1)C(F)(F)F
PDB
MMDB

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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281542
PNG
(US10022387, Example 68)
Show SMILES OC(c1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2CCCCc2[nH]1)C(F)(F)F
PDB
MMDB

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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281553
PNG
(N-(5-(2-(1H-Benzo[d]imidazol-2- yl)benzo[d]oxazol-...)
Show SMILES CCS(=O)(=O)Nc1cc(cnc1OC)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
MMDB

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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281493
PNG
(N-(5-(2-(1H- Benzo[d]imidazol- 2- yl)benzo[d]oxazo...)
Show SMILES Fc1cccc(c1)S(=O)(=O)Nc1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281495
PNG
(N'-{5-[2-(1H- Benzimidazol-2- yl)-1,3- benzoxazol-...)
Show SMILES CN(C)S(=O)(=O)Nc1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281499
PNG
(N-(5-(2-(1H- Benzo[d]imidazol- 2 - yl)benzo[d]oxaz...)
Show SMILES CCS(=O)(=O)Nc1cc(cnc1C)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281503
PNG
(N-(5-(2-(1H- Benzo[d]imidazol- 2- yl)benzo[d]oxazo...)
Show SMILES Fc1ccc(cc1)S(=O)(=O)Nc1cc(cnc1Cl)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
MMDB

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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281505
PNG
(N-(5-(2-(1H- Benzo[d]imidazol- 2- yl)benzo[d]oxazo...)
Show SMILES CN1CCN(CC1)S(=O)(=O)Nc1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281506
PNG
(N-(5-(2-(1H- Benzo[d]imidazol- 2- yl)benzo[d]oxazo...)
Show SMILES CN1CCN(CC1)S(=O)(=O)Nc1cc(cnc1F)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281511
PNG
(US10022387, Example 37)
Show SMILES CN(C)S(=O)(=O)c1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
MMDB

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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281523
PNG
(US10022387, Example 49)
Show SMILES c1n[nH]c2ccc(cc12)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
Show InChI InChI=1S/C21H11N5O/c1-2-4-17-16(3-1)23-20(24-17)21-25-18-8-6-13(10-19(18)27-21)12-5-7-15-14(9-12)11-22-26-15/h1-11H/b13-12+
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281526
PNG
(US10022387, Example 52)
Show SMILES CCS(=O)(=O)n1ncc2ccc(cc12)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281533
PNG
(US10022387, Example 59)
Show SMILES CCNS(=O)(=O)c1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281537
PNG
(US10022387, Example 63)
Show SMILES CCS(=O)(=O)Nc1cncc(c1)-c1ccc2nc(oc2c1)-c1nc(C)c(C)[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281539
PNG
(US10022387, Example 65)
Show SMILES CCS(=O)(=O)Nc1cc(cnc1OC)-c1ccc2nc(oc2c1)-c1nc(C)c(C)[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281541
PNG
(US10022387, Example 67)
Show SMILES Cc1nc([nH]c1C)-c1nc2ccc(cc2o1)-c1cncc(c1)C(O)C(F)(F)F
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281548
PNG
(1-(5-(2-(1H-Benzo[d]imidazol-2- yl)benzo[d]oxazol-...)
Show SMILES OC(c1cc(cnc1F)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1)C(F)(F)F
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281551
PNG
(N-(5-(2-(1H-Benzo[d]imidazol-2- yl)benzo[d]oxazol-...)
Show SMILES FC(F)(F)CS(=O)(=O)Nc1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281497
PNG
(N'-{5-[2-(1H- Benzimidazol-2- yl)-1,3- benzoxazol-...)
Show SMILES CN(C)S(=O)(=O)Nc1cc(cnc1F)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281500
PNG
(N-(5-(2-(1H- Benzo[d]imidazol- 2 - yl)benzo[d]oxaz...)
Show SMILES CCS(=O)(=O)Nc1cc(cnc1Cl)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281502
PNG
(N-(5-(2-(1H- Benzo[d]imdiazol- 2 - yl)benzo[d]oxaz...)
Show SMILES Cc1ncc(cc1NS(=O)(=O)c1ccc(F)cc1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281503
PNG
(N-(5-(2-(1H- Benzo[d]imidazol- 2- yl)benzo[d]oxazo...)
Show SMILES Fc1ccc(cc1)S(=O)(=O)Nc1cc(cnc1Cl)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281513
PNG
(US10022387, Example 39)
Show SMILES Fc1ccc(cc1)S(=O)(=O)Nc1cncc(c1)-c1ccc2nc(oc2c1)-c1ncc[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281514
PNG
(N-(5-(2-(1H- Imidazol-2- yl)benzo[d]oxazol- 6-yl)p...)
Show SMILES CCS(=O)(=O)Nc1cncc(c1)-c1ccc2nc(oc2c1)-c1ncc[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281549
PNG
(N-(5-(2-(1H-Benzo[d]imidazol-2- yl)benzo[d]oxazol-...)
Show SMILES Fc1ncc(cc1NS(=O)(=O)CC(F)(F)F)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281550
PNG
(N-(5-(2-(1H-Benzo[d]imidazol-2- yl)benzo[d]oxazol-...)
Show SMILES Cc1ncc(cc1NS(=O)(=O)CC(F)(F)F)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281493
PNG
(N-(5-(2-(1H- Benzo[d]imidazol- 2- yl)benzo[d]oxazo...)
Show SMILES Fc1cccc(c1)S(=O)(=O)Nc1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281498
PNG
(N-(5-(2-(1H- Benzo[d]imidazol- 2 - yl)benzo[d]oxaz...)
Show SMILES CC(C)S(=O)(=O)Nc1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
MMDB

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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281504
PNG
(N-(5-(2-(1H- Benzo[d]imidazol- 2 - yl)benzo[d]oxaz...)
Show SMILES Fc1ccc(cc1)S(=O)(=O)Nc1cc(cnc1F)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281524
PNG
(US10022387, Example 50)
Show SMILES Cc1n[nH]c2ccc(cc12)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
Show InChI InChI=1S/C22H13N5O/c1-12-15-10-13(6-8-16(15)27-26-12)14-7-9-19-20(11-14)28-22(25-19)21-23-17-4-2-3-5-18(17)24-21/h2-11H,1H3/b14-13+
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281541
PNG
(US10022387, Example 67)
Show SMILES Cc1nc([nH]c1C)-c1nc2ccc(cc2o1)-c1cncc(c1)C(O)C(F)(F)F
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281548
PNG
(1-(5-(2-(1H-Benzo[d]imidazol-2- yl)benzo[d]oxazol-...)
Show SMILES OC(c1cc(cnc1F)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1)C(F)(F)F
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281554
PNG
(US10022387, Example 80)
Show SMILES CCS(=O)(=O)Nc1cc(cc(F)c1OC)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281479
PNG
(US10022387, Example 4 | US10022387, Example 5)
Show SMILES COc1cncc(c1)-c1ccc2nc(oc2c1)-c1cc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281479
PNG
(US10022387, Example 4 | US10022387, Example 5)
Show SMILES COc1cncc(c1)-c1ccc2nc(oc2c1)-c1cc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281488
PNG
(US10022387, Example 14)
Show SMILES Oc1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281494
PNG
(N-(5-(2-(1H- Benzo[d]imidazol- 2- yl)benzo[d]oxazo...)
Show SMILES O=S(=O)(Nc1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1)C1CCCCC1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281501
PNG
(N-(5-(2-(1H- Benzo[d]imidazol- 2 - yl)benzo[d]oxaz...)
Show SMILES CCS(=O)(=O)Nc1cc(cnc1F)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281509
PNG
(US10022387, Example 35)
Show SMILES N#Cc1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281515
PNG
(N'-{5-[2-(1H- Imidazol-2-yl)-1,3- benzoxazol-6- yl...)
Show SMILES CN(C)S(=O)(=O)Nc1cncc(c1)-c1ccc2nc(oc2c1)-c1ncc[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281518
PNG
(6-(5- Methoxypyridin- 3-yl)-2-(2- phenyl-1H- imida...)
Show SMILES COc1cncc(c1)-c1ccc2nc(oc2c1)-c1cnc([nH]1)-c1ccccc1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281524
PNG
(US10022387, Example 50)
Show SMILES Cc1n[nH]c2ccc(cc12)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
Show InChI InChI=1S/C22H13N5O/c1-12-15-10-13(6-8-16(15)27-26-12)14-7-9-19-20(11-14)28-22(25-19)21-23-17-4-2-3-5-18(17)24-21/h2-11H,1H3/b14-13+
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281531
PNG
(US10022387, Example 57)
Show SMILES CCn1ncc2ncc(cc12)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281532
PNG
(US10022387, Example 58)
Show SMILES OC1CCN(C1)S(=O)(=O)c1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281534
PNG
(US10022387, Example 60)
Show SMILES CCS(=O)(=O)Nc1cc(ccc1F)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281538
PNG
(US10022387, Example 64)
Show SMILES CCCc1nc([nH]c1C)-c1nc2ccc(cc2o1)-c1cncc(NS(=O)(=O)CC)c1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281550
PNG
(N-(5-(2-(1H-Benzo[d]imidazol-2- yl)benzo[d]oxazol-...)
Show SMILES Cc1ncc(cc1NS(=O)(=O)CC(F)(F)F)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281485
PNG
(US10022387, Example 11)
Show SMILES COc1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2cc(C)ccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281491
PNG
(US10022387, Example 17)
Show SMILES Fc1ccc(cc1)S(=O)(=O)Nc1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281497
PNG
(N'-{5-[2-(1H- Benzimidazol-2- yl)-1,3- benzoxazol-...)
Show SMILES CN(C)S(=O)(=O)Nc1cc(cnc1F)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281499
PNG
(N-(5-(2-(1H- Benzo[d]imidazol- 2 - yl)benzo[d]oxaz...)
Show SMILES CCS(=O)(=O)Nc1cc(cnc1C)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281504
PNG
(N-(5-(2-(1H- Benzo[d]imidazol- 2 - yl)benzo[d]oxaz...)
Show SMILES Fc1ccc(cc1)S(=O)(=O)Nc1cc(cnc1F)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281506
PNG
(N-(5-(2-(1H- Benzo[d]imidazol- 2- yl)benzo[d]oxazo...)
Show SMILES CN1CCN(CC1)S(=O)(=O)Nc1cc(cnc1F)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281512
PNG
(US10022387, Example 38)
Show SMILES O=S(=O)(N1CCOCC1)c1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281522
PNG
(US10022387, Example 48)
Show SMILES C(c1ccccc1)n1cc(cn1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
MMDB

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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281525
PNG
(US10022387, Example 51)
Show SMILES Fc1ccc(cc1F)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
MMDB

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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281540
PNG
(US10022387, Example 66)
Show SMILES CCS(=O)(=O)Nc1cc(cnc1OC)-c1ccc2nc(oc2c1)-c1nc2CCCCc2[nH]1
PDB
MMDB

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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281532
PNG
(US10022387, Example 58)
Show SMILES OC1CCN(C1)S(=O)(=O)c1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281483
PNG
(US10022387, Example 8)
Show SMILES COc1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2ccc(Br)cc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281489
PNG
(US10022387, Example 15)
Show SMILES CC(C)Oc1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281501
PNG
(N-(5-(2-(1H- Benzo[d]imidazol- 2 - yl)benzo[d]oxaz...)
Show SMILES CCS(=O)(=O)Nc1cc(cnc1F)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281514
PNG
(N-(5-(2-(1H- Imidazol-2- yl)benzo[d]oxazol- 6-yl)p...)
Show SMILES CCS(=O)(=O)Nc1cncc(c1)-c1ccc2nc(oc2c1)-c1ncc[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281495
PNG
(N'-{5-[2-(1H- Benzimidazol-2- yl)-1,3- benzoxazol-...)
Show SMILES CN(C)S(=O)(=O)Nc1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281531
PNG
(US10022387, Example 57)
Show SMILES CCn1ncc2ncc(cc12)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
MMDB

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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281544
PNG
(2-(1H-Benzo[d]imidazol-2-yl)-6-(2- fluoropyrimidin...)
Show SMILES Fc1ncc(cn1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
MMDB

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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281551
PNG
(N-(5-(2-(1H-Benzo[d]imidazol-2- yl)benzo[d]oxazol-...)
Show SMILES FC(F)(F)CS(=O)(=O)Nc1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281492
PNG
(N-(5-(2-(1H- Benzo[d]imidazol- 2- yl)benzo[d]oxazo...)
Show SMILES CCS(=O)(=O)Nc1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281479
PNG
(US10022387, Example 4 | US10022387, Example 5)
Show SMILES COc1cncc(c1)-c1ccc2nc(oc2c1)-c1cc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281536
PNG
(US10022387, Example 62)
Show SMILES Cc1nc([nH]c1C)-c1nc2ccc(cc2o1)-c1cncc(c1)S(C)(=O)=O
PDB
MMDB

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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281476
PNG
(US10022387, Example 1)
Show SMILES COc1cncc(c1)-c1ccc2nc(oc2c1)-c1ncc[nH]1
PDB
MMDB

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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281482
PNG
(US10022387, Example 7)
Show SMILES COc1cncc(c1)-c1ccc2nc(ccc2c1)-c1nc2ccccc2[nH]1
PDB
MMDB

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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281490
PNG
(US10022387, Example 16)
Show SMILES FC(F)Oc1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281515
PNG
(N'-{5-[2-(1H- Imidazol-2-yl)-1,3- benzoxazol-6- yl...)
Show SMILES CN(C)S(=O)(=O)Nc1cncc(c1)-c1ccc2nc(oc2c1)-c1ncc[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281516
PNG
(US10022387, Example 42)
Show SMILES COc1cncc(c1)-c1ccc2nc(oc2c1)-c1cnc([nH]1)C1CC1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281545
PNG
(2-(5-(2-(1H-Benzo[d]imidazol-2- yl)benzo[d]oxazol-...)
Show SMILES OC(=O)Cc1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281484
PNG
(US10022387, Example 10)
Show SMILES COc1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2cc(F)ccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281494
PNG
(N-(5-(2-(1H- Benzo[d]imidazol- 2- yl)benzo[d]oxazo...)
Show SMILES O=S(=O)(Nc1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1)C1CCCCC1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281507
PNG
(N-(5-(2-(1H- Benzo[d]imidazol- 2 - yl)benzo[d]oxaz...)
Show SMILES CC(=O)Nc1cc(cnc1F)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281511
PNG
(US10022387, Example 37)
Show SMILES CN(C)S(=O)(=O)c1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281537
PNG
(US10022387, Example 63)
Show SMILES CCS(=O)(=O)Nc1cncc(c1)-c1ccc2nc(oc2c1)-c1nc(C)c(C)[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281487
PNG
(US10022387, Example 13)
Show SMILES Brc1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
MMDB

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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281487
PNG
(US10022387, Example 13)
Show SMILES Brc1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
MMDB

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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281488
PNG
(US10022387, Example 14)
Show SMILES Oc1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
MMDB

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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281522
PNG
(US10022387, Example 48)
Show SMILES C(c1ccccc1)n1cc(cn1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
MMDB

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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281523
PNG
(US10022387, Example 49)
Show SMILES c1n[nH]c2ccc(cc12)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
Show InChI InChI=1S/C21H11N5O/c1-2-4-17-16(3-1)23-20(24-17)21-25-18-8-6-13(10-19(18)27-21)12-5-7-15-14(9-12)11-22-26-15/h1-11H/b13-12+
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281534
PNG
(US10022387, Example 60)
Show SMILES CCS(=O)(=O)Nc1cc(ccc1F)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281536
PNG
(US10022387, Example 62)
Show SMILES Cc1nc([nH]c1C)-c1nc2ccc(cc2o1)-c1cncc(c1)S(C)(=O)=O
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281544
PNG
(2-(1H-Benzo[d]imidazol-2-yl)-6-(2- fluoropyrimidin...)
Show SMILES Fc1ncc(cn1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281552
PNG
(N-(2-(2-(1H-Benzo[d]imidazol-2- yl)benzo[d]oxazol-...)
Show SMILES CCS(=O)(=O)Nc1cc(ncc1F)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281552
PNG
(N-(2-(2-(1H-Benzo[d]imidazol-2- yl)benzo[d]oxazol-...)
Show SMILES CCS(=O)(=O)Nc1cc(ncc1F)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281517
PNG
(6-(5- Methoxypyridin- 3-yl)-2-(2- (tetrahydrofuran...)
Show SMILES COc1cncc(c1)-c1ccc2nc(oc2c1)-c1cnc([nH]1)C1CCOC1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281543
PNG
(2-(1H-Benzo[d]imidazol-2-yl)-6-(6- fluoro-5-methox...)
Show SMILES CCc1cc(cnc1F)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281479
PNG
(US10022387, Example 4 | US10022387, Example 5)
Show SMILES COc1cncc(c1)-c1ccc2nc(oc2c1)-c1cc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281498
PNG
(N-(5-(2-(1H- Benzo[d]imidazol- 2 - yl)benzo[d]oxaz...)
Show SMILES CC(C)S(=O)(=O)Nc1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281507
PNG
(N-(5-(2-(1H- Benzo[d]imidazol- 2 - yl)benzo[d]oxaz...)
Show SMILES CC(=O)Nc1cc(cnc1F)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281518
PNG
(6-(5- Methoxypyridin- 3-yl)-2-(2- phenyl-1H- imida...)
Show SMILES COc1cncc(c1)-c1ccc2nc(oc2c1)-c1cnc([nH]1)-c1ccccc1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281519
PNG
(2-(2-Ethyl-1H- imidazol-5-yl)- 6-(5- methoxypyridi...)
Show SMILES CCc1ncc([nH]1)-c1nc2ccc(cc2o1)-c1cncc(OC)c1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281519
PNG
(2-(2-Ethyl-1H- imidazol-5-yl)- 6-(5- methoxypyridi...)
Show SMILES CCc1ncc([nH]1)-c1nc2ccc(cc2o1)-c1cncc(OC)c1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281521
PNG
(US10022387, Example 47)
Show SMILES COc1cncc(c1)-c1ccc2nc(oc2c1)-c1cc(n[nH]1)-c1ccccc1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281476
PNG
(US10022387, Example 1)
Show SMILES COc1cncc(c1)-c1ccc2nc(oc2c1)-c1ncc[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281478
PNG
(US10022387, Example 3)
Show SMILES COc1cncc(c1)-c1ccc2nc(oc2c1)-c1ccc[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281529
PNG
(US10022387, Example 55)
Show SMILES C(N1CCN(CC1)c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1)c1ccccc1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281546
PNG
(2-(1H-Benzo[d]imidazol-2-yl)-6-(5- (dimethylphosph...)
Show SMILES CP(C)(=O)c1cc(cnc1F)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281554
PNG
(US10022387, Example 80)
Show SMILES CCS(=O)(=O)Nc1cc(cc(F)c1OC)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281477
PNG
(US10022387, Example 2)
Show SMILES COc1cncc(c1)-c1ccc2nc(oc2c1)-c1cnc[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281477
PNG
(US10022387, Example 2)
Show SMILES COc1cncc(c1)-c1ccc2nc(oc2c1)-c1cnc[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281478
PNG
(US10022387, Example 3)
Show SMILES COc1cncc(c1)-c1ccc2nc(oc2c1)-c1ccc[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281485
PNG
(US10022387, Example 11)
Show SMILES COc1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2cc(C)ccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281516
PNG
(US10022387, Example 42)
Show SMILES COc1cncc(c1)-c1ccc2nc(oc2c1)-c1cnc([nH]1)C1CC1
PDB
MMDB

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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281527
PNG
(US10022387, Example 53 | US10022387, Example 54)
Show SMILES CCn1cc2ccc(cc2n1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281527
PNG
(US10022387, Example 53 | US10022387, Example 54)
Show SMILES CCn1cc2ccc(cc2n1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281481
PNG
(US10022387, Example 6)
Show SMILES COc1cncc(c1)-c1ccc2nc(sc2c1)-c1nc2ccccc2[nH]1
PDB
MMDB

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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281482
PNG
(US10022387, Example 7)
Show SMILES COc1cncc(c1)-c1ccc2nc(ccc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281486
PNG
(US10022387, Example 12)
Show SMILES COc1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2c(C)cccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281508
PNG
(US10022387, Example 34)
Show SMILES CN(C)c1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281525
PNG
(US10022387, Example 51)
Show SMILES Fc1ccc(cc1F)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
MMDB

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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281529
PNG
(US10022387, Example 55)
Show SMILES C(N1CCN(CC1)c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1)c1ccccc1
PDB
MMDB

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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281530
PNG
(US10022387, Example 56)
Show SMILES Nc1ncc(cc1C(F)(F)F)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
MMDB

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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281533
PNG
(US10022387, Example 59)
Show SMILES CCNS(=O)(=O)c1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281510
PNG
(US10022387, Example 36)
Show SMILES CS(=O)(=O)c1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281512
PNG
(US10022387, Example 38)
Show SMILES O=S(=O)(N1CCOCC1)c1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281517
PNG
(6-(5- Methoxypyridin- 3-yl)-2-(2- (tetrahydrofuran...)
Show SMILES COc1cncc(c1)-c1ccc2nc(oc2c1)-c1cnc([nH]1)C1CCOC1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281520
PNG
(US10022387, Example 46)
Show SMILES COc1cncc(c1)-c1ccc2nc(oc2c1)-c1cc(C)n[nH]1
PDB
MMDB

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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281521
PNG
(US10022387, Example 47)
Show SMILES COc1cncc(c1)-c1ccc2nc(oc2c1)-c1cc(n[nH]1)-c1ccccc1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281545
PNG
(2-(5-(2-(1H-Benzo[d]imidazol-2- yl)benzo[d]oxazol-...)
Show SMILES OC(=O)Cc1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281492
PNG
(N-(5-(2-(1H- Benzo[d]imidazol- 2- yl)benzo[d]oxazo...)
Show SMILES CCS(=O)(=O)Nc1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
MMDB

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n/an/a<5.00E+3n/an/an/an/an/an/a



Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281481
PNG
(US10022387, Example 6)
Show SMILES COc1cncc(c1)-c1ccc2nc(sc2c1)-c1nc2ccccc2[nH]1
PDB
MMDB

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Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281484
PNG
(US10022387, Example 10)
Show SMILES COc1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2cc(F)ccc2[nH]1
PDB
MMDB

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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281489
PNG
(US10022387, Example 15)
Show SMILES CC(C)Oc1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
MMDB

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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281500
PNG
(N-(5-(2-(1H- Benzo[d]imidazol- 2 - yl)benzo[d]oxaz...)
Show SMILES CCS(=O)(=O)Nc1cc(cnc1Cl)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
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Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (human))
BDBM281509
PNG
(US10022387, Example 35)
Show SMILES N#Cc1cncc(c1)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1
PDB
MMDB

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n/an/a>5.00E+3n/an/an/an/an/an/a



Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (human))
BDBM281520
PNG
(US10022387, Example 46)
Show SMILES COc1cncc(c1)-c1ccc2nc(oc2c1)-c1cc(C)n[nH]1
PDB
MMDB

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n/an/a>5.00E+3n/an/an/an/an/an/a



Incyte Corporation

US Patent


Assay Description
γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...


US Patent US10022387 (2018)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%