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Patent code US10023519

Compile Data Set for Download or QSAR
Found 68 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281683
PNG
(Cis-2-(3-(4-(5-chloro-2,2-dimethyl-2,3-dihydrobenz...)
Show SMILES CC1(C)Cc2cc(Cl)cc(c2O1)-c1ccc(cc1)C1C[C@@H](C1)OCC(O)=O
Show InChI InChI=1S/C22H23ClO4/c1-22(2)11-16-7-17(23)10-19(21(16)27-22)14-5-3-13(4-6-14)15-8-18(9-15)26-12-20(24)25/h3-7,10,15,18H,8-9,11-12H2,1-2H3,(H,24,25)/t15?,18-
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n/an/an/an/a 2.90E+3n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281688
PNG
(US10023519, Example 29)
Show SMILES Cc1ccc(Oc2ccc(F)c(c2)-c2ccc(cc2)[C@@H]2C[C@@H](C2)OCC(O)=O)nn1
Show InChI InChI=1S/C23H21FN2O4/c1-14-2-9-22(26-25-14)30-18-7-8-21(24)20(12-18)16-5-3-15(4-6-16)17-10-19(11-17)29-13-23(27)28/h2-9,12,17,19H,10-11,13H2,1H3,(H,27,28)/t17-,19+
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n/an/an/an/a 5.00E+3n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281690
PNG
(Cis-2-(3-(2′-fluoro-5′-(p-tolyloxy)-[1...)
Show SMILES Cc1ccc(Oc2ccc(F)c(c2)-c2ccc(cc2)[C@@H]2C[C@@H](C2)OCC(O)=O)cc1
Show InChI InChI=1S/C25H23FO4/c1-16-2-8-20(9-3-16)30-21-10-11-24(26)23(14-21)18-6-4-17(5-7-18)19-12-22(13-19)29-15-25(27)28/h2-11,14,19,22H,12-13,15H2,1H3,(H,27,28)/t19-,22+
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n/an/an/an/a 710n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281692
PNG
(Cis-2-(3-(5′-(cyclohexyloxy)-2′-fluoro...)
Show SMILES OC(=O)COC1CC(C1)c1ccc(cc1)-c1cc(OC2CCCCC2)ccc1F
Show InChI InChI=1S/C24H27FO4/c25-23-11-10-20(29-19-4-2-1-3-5-19)14-22(23)17-8-6-16(7-9-17)18-12-21(13-18)28-15-24(26)27/h6-11,14,18-19,21H,1-5,12-13,15H2,(H,26,27)
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n/an/an/an/a 760n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281693
PNG
(Cis-2-(3-(2′,3′-difluoro-5′-(4-f...)
Show SMILES OC(=O)CO[C@H]1C[C@H](C1)c1ccc(cc1)-c1cc(Oc2ccc(F)cc2)cc(F)c1F
Show InChI InChI=1S/C24H19F3O4/c25-17-5-7-18(8-6-17)31-20-11-21(24(27)22(26)12-20)15-3-1-14(2-4-15)16-9-19(10-16)30-13-23(28)29/h1-8,11-12,16,19H,9-10,13H2,(H,28,29)/t16-,19+
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n/an/an/an/a 590n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281699
PNG
(2-(3-(2′-Fluoro-5′-phenoxy-[1,1′...)
Show SMILES OC(=O)[C@H]1CC1[C@H]1C[C@H](C1)c1ccc(cc1)-c1cc(Oc2ccccc2)ccc1F
Show InChI InChI=1S/C26H23FO3/c27-25-11-10-21(30-20-4-2-1-3-5-20)14-23(25)17-8-6-16(7-9-17)18-12-19(13-18)22-15-24(22)26(28)29/h1-11,14,18-19,22,24H,12-13,15H2,(H,28,29)/t18-,19+,22?,24-/m0/s1
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n/an/an/an/a 9.27E+3n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281700
PNG
(5-(2′-Fluoro-5′-isopropoxy-[1,1′...)
Show SMILES CC(C)Oc1ccc(F)c(c1)-c1ccc(cc1)C1CC2(C[C@H]2C(O)=O)C1
Show InChI InChI=1S/C22H23FO3/c1-13(2)26-17-7-8-20(23)18(9-17)15-5-3-14(4-6-15)16-10-22(11-16)12-19(22)21(24)25/h3-9,13,16,19H,10-12H2,1-2H3,(H,24,25)/t16?,19-,22?/m0/s1
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n/an/an/an/a 3.20E+4n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281708
PNG
(3-((2′-Fluoro-5′-isopropoxy-[1,1′...)
Show SMILES CC(C)Oc1ccc(F)c(c1)-c1ccc(C[C@H]2C[C@H](C2)C(O)=O)cc1
Show InChI InChI=1S/C21H23FO3/c1-13(2)25-18-7-8-20(22)19(12-18)16-5-3-14(4-6-16)9-15-10-17(11-15)21(23)24/h3-8,12-13,15,17H,9-11H2,1-2H3,(H,23,24)/t15-,17+
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n/an/an/an/a 500n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281716
PNG
(2-(2-(3-(3-Phenoxybenzyloxy)cyclobutyl)ethoxy)acet...)
Show SMILES OC(=O)COCCC1CC(C1)OCc1cccc(Oc2ccccc2)c1
Show InChI InChI=1S/C21H24O5/c22-21(23)15-24-10-9-16-11-20(12-16)25-14-17-5-4-8-19(13-17)26-18-6-2-1-3-7-18/h1-8,13,16,20H,9-12,14-15H2,(H,22,23)
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n/an/an/an/a 700n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281723
PNG
(Trans-3-((2′-fluoro-5′-phenoxy-[1,1...)
Show SMILES OC(=O)[C@H]1C[C@@H](C1)Oc1ccc(cc1)-c1cc(Oc2ccccc2)ccc1F
Show InChI InChI=1S/C23H19FO4/c24-22-11-10-19(27-17-4-2-1-3-5-17)14-21(22)15-6-8-18(9-7-15)28-20-12-16(13-20)23(25)26/h1-11,14,16,20H,12-13H2,(H,25,26)/t16-,20-
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n/an/an/an/a 440n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281668
PNG
(US10023519, Example 9)
Show SMILES OC(=O)CO[C@H]1C[C@H](C1)c1ccc(cc1)-c1cccc(Cc2ccccc2)c1
Show InChI InChI=1S/C25H24O3/c26-25(27)17-28-24-15-23(16-24)21-11-9-20(10-12-21)22-8-4-7-19(14-22)13-18-5-2-1-3-6-18/h1-12,14,23-24H,13,15-17H2,(H,26,27)/t23-,24+
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n/an/an/an/a 1.59E+3n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281677
PNG
(US10023519, Example 18)
Show SMILES CC(C)Oc1cc(F)cc(c1)-c1ccc(cc1)[C@@H]1C[C@@H](C1)OCC(O)=O
Show InChI InChI=1S/C21H23FO4/c1-13(2)26-20-10-16(7-18(22)11-20)14-3-5-15(6-4-14)17-8-19(9-17)25-12-21(23)24/h3-7,10-11,13,17,19H,8-9,12H2,1-2H3,(H,23,24)/t17-,19+
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n/an/an/an/a 3.13E+3n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281679
PNG
(Cis-2-(3-(2′-fluoro-5′-((6-methylpyrid...)
Show SMILES Cc1ccc(Oc2ccc(F)c(c2)-c2ccc(cc2)C2C[C@@H](C2)OCC(O)=O)cn1
Show InChI InChI=1S/C24H22FNO4/c1-15-2-7-20(13-26-15)30-19-8-9-23(25)22(12-19)17-5-3-16(4-6-17)18-10-21(11-18)29-14-24(27)28/h2-9,12-13,18,21H,10-11,14H2,1H3,(H,27,28)/t18?,21-
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n/an/an/an/a 270n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281701
PNG
(US10023519, Example 42)
Show SMILES CC(C)Oc1ccc(F)c(c1)-c1ccc(cc1)C1CC2(C[C@@H]2C(O)=O)C1
Show InChI InChI=1S/C22H23FO3/c1-13(2)26-17-7-8-20(23)18(9-17)15-5-3-14(4-6-15)16-10-22(11-16)12-19(22)21(24)25/h3-9,13,16,19H,10-12H2,1-2H3,(H,24,25)/t16?,19-,22?/m1/s1
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n/an/an/an/a 2.21E+3n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281663
PNG
(US10023519, Example 4)
Show SMILES OC(=O)CO[C@H]1C[C@H](C1)c1ccc(cc1)-c1ccccc1Oc1ccccc1
Show InChI InChI=1S/C24H22O4/c25-24(26)16-27-21-14-19(15-21)17-10-12-18(13-11-17)22-8-4-5-9-23(22)28-20-6-2-1-3-7-20/h1-13,19,21H,14-16H2,(H,25,26)/t19-,21+
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n/an/an/an/a 1.46E+3n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281669
PNG
(US10023519, Example 10)
Show SMILES CC(C)Oc1cccc(c1F)-c1ccc(cc1)[C@@H]1C[C@@H](C1)OCC(O)=O
Show InChI InChI=1S/C21H23FO4/c1-13(2)26-19-5-3-4-18(21(19)22)15-8-6-14(7-9-15)16-10-17(11-16)25-12-20(23)24/h3-9,13,16-17H,10-12H2,1-2H3,(H,23,24)/t16-,17+
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n/an/an/an/a 1.02E+3n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281670
PNG
(US10023519, Example 11)
Show SMILES CC(C)Oc1cc(Cl)cc(c1)-c1ccc(cc1)[C@@H]1C[C@@H](C1)OCC(O)=O
Show InChI InChI=1S/C21H23ClO4/c1-13(2)26-20-10-16(7-18(22)11-20)14-3-5-15(6-4-14)17-8-19(9-17)25-12-21(23)24/h3-7,10-11,13,17,19H,8-9,12H2,1-2H3,(H,23,24)/t17-,19+
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UniChem
n/an/an/an/a 560n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281678
PNG
(US10023519, Example 19)
Show SMILES COc1cc(OC(C)C)cc(c1)-c1ccc(cc1)[C@@H]1C[C@@H](C1)OCC(O)=O
Show InChI InChI=1S/C22H26O5/c1-14(2)27-21-11-17(8-19(12-21)25-3)15-4-6-16(7-5-15)18-9-20(10-18)26-13-22(23)24/h4-8,11-12,14,18,20H,9-10,13H2,1-3H3,(H,23,24)/t18-,20+
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n/an/an/an/a 1.59E+3n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281698
PNG
(Trans-2-(3-(2′-fluoro-5′-phenoxy-[1,1&...)
Show SMILES OC(=O)CO[C@H]1CC(C1)c1ccc(cc1)-c1cc(Oc2ccccc2)ccc1F
Show InChI InChI=1S/C24H21FO4/c25-23-11-10-20(29-19-4-2-1-3-5-19)14-22(23)17-8-6-16(7-9-17)18-12-21(13-18)28-15-24(26)27/h1-11,14,18,21H,12-13,15H2,(H,26,27)/t18?,21-
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n/an/an/an/a 410n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281702
PNG
(2-(3-(2′-Fluoro-5′-isopropoxy-[1,1R...)
Show SMILES CC(C)Oc1ccc(F)c(c1)-c1ccc(cc1)C1CC(CC(O)=O)C1
Show InChI InChI=1S/C21H23FO3/c1-13(2)25-18-7-8-20(22)19(12-18)16-5-3-15(4-6-16)17-9-14(10-17)11-21(23)24/h3-8,12-14,17H,9-11H2,1-2H3,(H,23,24)
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n/an/an/an/a 140n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281706
PNG
(3-((2′-Fluoro-5′-isopropoxy-[1,1′...)
Show InChI InChI=1S/C21H21FO3/c1-13(2)25-18-7-8-20(22)19(12-18)16-5-3-14(4-6-16)9-15-10-17(11-15)21(23)24/h3-9,12-13,17H,10-11H2,1-2H3,(H,23,24)/b15-9-
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n/an/an/an/a 460n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281713
PNG
(2-((3-(3-Phenoxybenzyloxy)cyclobutyl)methoxy)aceti...)
Show SMILES OC(=O)COCC1CC(C1)OCc1cccc(Oc2ccccc2)c1
Show InChI InChI=1S/C20H22O5/c21-20(22)14-23-12-16-10-19(11-16)24-13-15-5-4-8-18(9-15)25-17-6-2-1-3-7-17/h1-9,16,19H,10-14H2,(H,21,22)
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UniChem
n/an/an/an/a 3.85E+3n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281721
PNG
(3-(3-(Cis-1-methyl-3-(3-phenoxyphenyl)cyclobutyl)p...)
Show SMILES C[C@@]1(CCCOCCC(O)=O)C[C@@H](C1)c1cccc(Oc2ccccc2)c1
Show InChI InChI=1S/C23H28O4/c1-23(12-6-13-26-14-11-22(24)25)16-19(17-23)18-7-5-10-21(15-18)27-20-8-3-2-4-9-20/h2-5,7-10,15,19H,6,11-14,16-17H2,1H3,(H,24,25)/t19-,23+
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UniChem
n/an/an/an/a 570n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281722
PNG
(Trans-2-(((3-(3-phenoxyphenyl)cyclobutyl)methoxy)m...)
Show SMILES OC(=O)[C@H]1C[C@@H]1COCC1CC(C1)c1cccc(Oc2ccccc2)c1
Show InChI InChI=1S/C22H24O4/c23-22(24)21-12-18(21)14-25-13-15-9-17(10-15)16-5-4-8-20(11-16)26-19-6-2-1-3-7-19/h1-8,11,15,17-18,21H,9-10,12-14H2,(H,23,24)/t15?,17?,18-,21+/m1/s1
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UniChem
n/an/an/an/a 1.26E+3n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281661
PNG
(US10023519, Example 2)
Show SMILES CC(C)Oc1ccc(F)c(c1)-c1ccc(cc1)[C@@H]1C[C@@H](C1)OCC(O)=O
Show InChI InChI=1S/C21H23FO4/c1-13(2)26-17-7-8-20(22)19(11-17)15-5-3-14(4-6-15)16-9-18(10-16)25-12-21(23)24/h3-8,11,13,16,18H,9-10,12H2,1-2H3,(H,23,24)/t16-,18+
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n/an/an/an/a 530n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281685
PNG
(US10023519, Example 26)
Show SMILES OC(=O)CO[C@H]1C[C@H](C1)c1ccc(cc1)-c1cc(Oc2ccccn2)ccc1F
Show InChI InChI=1S/C23H20FNO4/c24-21-9-8-18(29-22-3-1-2-10-25-22)13-20(21)16-6-4-15(5-7-16)17-11-19(12-17)28-14-23(26)27/h1-10,13,17,19H,11-12,14H2,(H,26,27)/t17-,19+
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n/an/an/an/a 490n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281691
PNG
(Cis-2-(3-(2′-fluoro-5′-(3-fluorophenox...)
Show SMILES OC(=O)CO[C@H]1C[C@H](C1)c1ccc(cc1)-c1cc(Oc2cccc(F)c2)ccc1F
Show InChI InChI=1S/C24H20F2O4/c25-18-2-1-3-19(12-18)30-20-8-9-23(26)22(13-20)16-6-4-15(5-7-16)17-10-21(11-17)29-14-24(27)28/h1-9,12-13,17,21H,10-11,14H2,(H,27,28)/t17-,21+
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n/an/an/an/a 230n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281704
PNG
(US10023519, Example 45)
Show SMILES CC(C)Oc1ccc(F)c(c1)-c1ccc(cc1)[C@@H]1C[C@H](CC(O)=O)C1
Show InChI InChI=1S/C21H23FO3/c1-13(2)25-18-7-8-20(22)19(12-18)16-5-3-15(4-6-16)17-9-14(10-17)11-21(23)24/h3-8,12-14,17H,9-11H2,1-2H3,(H,23,24)/t14-,17+
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UniChem
n/an/an/an/a 120n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281710
PNG
(US10023519, Example 51)
Show SMILES CC(C)Oc1ccc(F)c(c1)-c1ccc(C[C@@H]2C[C@H](CC(O)=O)C2)cc1
Show InChI InChI=1S/C22H25FO3/c1-14(2)26-19-7-8-21(23)20(13-19)18-5-3-15(4-6-18)9-16-10-17(11-16)12-22(24)25/h3-8,13-14,16-17H,9-12H2,1-2H3,(H,24,25)/t16-,17+
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UniChem
n/an/an/an/a 560n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281718
PNG
(2-(3-(Cis-3-(3-phenoxybenzyloxy)cyclobutyl)propoxy...)
Show SMILES OC(=O)COCCC[C@H]1C[C@H](C1)OCc1cccc(Oc2ccccc2)c1
Show InChI InChI=1S/C22H26O5/c23-22(24)16-25-11-5-7-17-12-21(13-17)26-15-18-6-4-10-20(14-18)27-19-8-2-1-3-9-19/h1-4,6,8-10,14,17,21H,5,7,11-13,15-16H2,(H,23,24)/t17-,21+
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n/an/an/an/a 520n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281724
PNG
(Cis-3-((2′-fluoro-5′-phenoxy-[1,1̸...)
Show SMILES OC(=O)[C@@H]1C[C@@H](C1)Oc1ccc(cc1)-c1cc(Oc2ccccc2)ccc1F
Show InChI InChI=1S/C23H19FO4/c24-22-11-10-19(27-17-4-2-1-3-5-17)14-21(22)15-6-8-18(9-7-15)28-20-12-16(13-20)23(25)26/h1-11,14,16,20H,12-13H2,(H,25,26)/t16-,20+
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n/an/an/an/a 2.27E+3n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281667
PNG
(US10023519, Example 8)
Show SMILES OC(=O)CO[C@H]1C[C@H](C1)c1ccc(cc1)-c1cc(OC(F)(F)F)ccc1Cl
Show InChI InChI=1S/C19H16ClF3O4/c20-17-6-5-14(27-19(21,22)23)9-16(17)12-3-1-11(2-4-12)13-7-15(8-13)26-10-18(24)25/h1-6,9,13,15H,7-8,10H2,(H,24,25)/t13-,15+
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n/an/an/an/a 900n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281671
PNG
(US10023519, Example 12)
Show SMILES CC(C)Oc1cc(C)cc(c1)-c1ccc(cc1)[C@@H]1C[C@@H](C1)OCC(O)=O
Show InChI InChI=1S/C22H26O4/c1-14(2)26-21-9-15(3)8-18(12-21)16-4-6-17(7-5-16)19-10-20(11-19)25-13-22(23)24/h4-9,12,14,19-20H,10-11,13H2,1-3H3,(H,23,24)/t19-,20+
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n/an/an/an/a 430n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281674
PNG
(US10023519, Example 15)
Show SMILES CC(C)Oc1ccc(F)c(c1F)-c1ccc(cc1)[C@@H]1C[C@@H](C1)OCC(O)=O
Show InChI InChI=1S/C21H22F2O4/c1-12(2)27-18-8-7-17(22)20(21(18)23)14-5-3-13(4-6-14)15-9-16(10-15)26-11-19(24)25/h3-8,12,15-16H,9-11H2,1-2H3,(H,24,25)/t15-,16+
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n/an/an/an/a 800n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281675
PNG
(US10023519, Example 16)
Show SMILES COc1ccc(OC(F)(F)F)cc1-c1ccc(cc1)[C@@H]1C[C@@H](C1)OCC(O)=O
Show InChI InChI=1S/C20H19F3O5/c1-26-18-7-6-15(28-20(21,22)23)10-17(18)13-4-2-12(3-5-13)14-8-16(9-14)27-11-19(24)25/h2-7,10,14,16H,8-9,11H2,1H3,(H,24,25)/t14-,16+
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n/an/an/an/a 480n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281676
PNG
(US10023519, Example 17)
Show SMILES OC(=O)CO[C@H]1C[C@H](C1)c1ccc(cc1)-c1cc(OC(F)(F)F)ccc1F
Show InChI InChI=1S/C19H16F4O4/c20-17-6-5-14(27-19(21,22)23)9-16(17)12-3-1-11(2-4-12)13-7-15(8-13)26-10-18(24)25/h1-6,9,13,15H,7-8,10H2,(H,24,25)/t13-,15+
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n/an/an/an/a 550n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281681
PNG
(US10023519, Example 22)
Show SMILES OC(=O)CO[C@H]1C[C@H](C1)c1ccc(cc1)-c1cc(Oc2cccc(F)c2)cnc1Cl
Show InChI InChI=1S/C23H19ClFNO4/c24-23-21(11-20(12-26-23)30-18-3-1-2-17(25)10-18)15-6-4-14(5-7-15)16-8-19(9-16)29-13-22(27)28/h1-7,10-12,16,19H,8-9,13H2,(H,27,28)/t16-,19+
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n/an/an/an/a 360n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281682
PNG
(US10023519, Example 23)
Show SMILES Cc1nc(C)c(s1)-c1ccc(cc1)[C@@H]1C[C@@H](C1)OCC(O)=O
Show InChI InChI=1S/C17H19NO3S/c1-10-17(22-11(2)18-10)13-5-3-12(4-6-13)14-7-15(8-14)21-9-16(19)20/h3-6,14-15H,7-9H2,1-2H3,(H,19,20)/t14-,15+
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n/an/an/an/a 3.46E+3n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281686
PNG
(US10023519, Example 27)
Show SMILES Cc1ncc(Oc2ccc(F)c(c2)-c2ccc(cc2)[C@@H]2C[C@@H](C2)OCC(O)=O)s1
Show InChI InChI=1S/C22H20FNO4S/c1-13-24-11-22(29-13)28-17-6-7-20(23)19(10-17)15-4-2-14(3-5-15)16-8-18(9-16)27-12-21(25)26/h2-7,10-11,16,18H,8-9,12H2,1H3,(H,25,26)/t16-,18+
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n/an/an/an/a 420n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281687
PNG
(US10023519, Example 28)
Show SMILES OC(=O)CO[C@H]1C[C@H](C1)c1ccc(cc1)-c1cc(Oc2cccnc2)ccc1F
Show InChI InChI=1S/C23H20FNO4/c24-22-8-7-18(29-19-2-1-9-25-13-19)12-21(22)16-5-3-15(4-6-16)17-10-20(11-17)28-14-23(26)27/h1-9,12-13,17,20H,10-11,14H2,(H,26,27)/t17-,20+
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n/an/an/an/a 660n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281693
PNG
(Cis-2-(3-(2′,3′-difluoro-5′-(4-f...)
Show SMILES OC(=O)CO[C@H]1C[C@H](C1)c1ccc(cc1)-c1cc(Oc2ccc(F)cc2)cc(F)c1F
Show InChI InChI=1S/C24H19F3O4/c25-17-5-7-18(8-6-17)31-20-11-21(24(27)22(26)12-20)15-3-1-14(2-4-15)16-9-19(10-16)30-13-23(28)29/h1-8,11-12,16,19H,9-10,13H2,(H,28,29)/t16-,19+
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n/an/an/an/a 240n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281714
PNG
(3-((Cis-3-(3-phenoxybenzyloxy)cyclobutyl)methoxy)p...)
Show SMILES OC(=O)CCOC[C@H]1C[C@H](C1)OCc1cccc(Oc2ccccc2)c1
Show InChI InChI=1S/C21H24O5/c22-21(23)9-10-24-14-17-12-20(13-17)25-15-16-5-4-8-19(11-16)26-18-6-2-1-3-7-18/h1-8,11,17,20H,9-10,12-15H2,(H,22,23)/t17-,20+
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n/an/an/an/a 470n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281715
PNG
(2-(3-(Trans-3-(3-phenoxyphenyl)cyclobutyl)propoxy)...)
Show SMILES CCOC(=O)CCC[C@H]1C[C@@H](C1)c1cccc(Oc2ccccc2)c1
Show InChI InChI=1S/C22H26O3/c1-2-24-22(23)13-6-8-17-14-19(15-17)18-9-7-12-21(16-18)25-20-10-4-3-5-11-20/h3-5,7,9-12,16-17,19H,2,6,8,13-15H2,1H3/t17-,19-
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n/an/an/an/a 170n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281672
PNG
(US10023519, Example 13)
Show SMILES CC(C)Sc1ncc(cc1-c1ccc(cc1)[C@@H]1C[C@@H](C1)OCC(O)=O)C(F)(F)F
Show InChI InChI=1S/C21H22F3NO3S/c1-12(2)29-20-18(9-16(10-25-20)21(22,23)24)14-5-3-13(4-6-14)15-7-17(8-15)28-11-19(26)27/h3-6,9-10,12,15,17H,7-8,11H2,1-2H3,(H,26,27)/t15-,17+
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n/an/an/an/a 2.61E+3n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281673
PNG
(US10023519, Example 14)
Show SMILES OC(=O)CO[C@H]1C[C@H](C1)c1ccc(cc1)-c1cccc(c1)C(=O)c1ccccc1
Show InChI InChI=1S/C25H22O4/c26-24(27)16-29-23-14-22(15-23)18-11-9-17(10-12-18)20-7-4-8-21(13-20)25(28)19-5-2-1-3-6-19/h1-13,22-23H,14-16H2,(H,26,27)/t22-,23+
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n/an/an/an/a 830n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281689
PNG
(Cis2-(3-(2′-fluoro-5′-((tetrahydro-2H-...)
Show SMILES OC(=O)CO[C@H]1C[C@H](C1)c1ccc(cc1)-c1cc(OC2CCCOC2)ccc1F
Show InChI InChI=1S/C23H25FO5/c24-22-8-7-18(29-19-2-1-9-27-13-19)12-21(22)16-5-3-15(4-6-16)17-10-20(11-17)28-14-23(25)26/h3-8,12,17,19-20H,1-2,9-11,13-14H2,(H,25,26)/t17-,19?,20+
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n/an/an/an/a 1.40E+3n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281694
PNG
(US10023519, Example 35)
Show SMILES Cc1ccc(Oc2cc(F)c(F)c(c2)-c2ccc(cc2)[C@@H]2C[C@@H](C2)OCC(O)=O)cc1F
Show InChI InChI=1S/C25H21F3O4/c1-14-2-7-18(11-22(14)26)32-20-10-21(25(28)23(27)12-20)16-5-3-15(4-6-16)17-8-19(9-17)31-13-24(29)30/h2-7,10-12,17,19H,8-9,13H2,1H3,(H,29,30)/t17-,19+
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n/an/an/an/a 290n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281697
PNG
(US10023519, Example 38)
Show SMILES Cc1ccc(Oc2cc(F)c(F)c(c2)-c2ccc(cc2)[C@@H]2C[C@@H](C2)OCC(O)=O)cc1
Show InChI InChI=1S/C25H22F2O4/c1-15-2-8-19(9-3-15)31-21-12-22(25(27)23(26)13-21)17-6-4-16(5-7-17)18-10-20(11-18)30-14-24(28)29/h2-9,12-13,18,20H,10-11,14H2,1H3,(H,28,29)/t18-,20+
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n/an/an/an/a 540n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281702
PNG
(2-(3-(2′-Fluoro-5′-isopropoxy-[1,1R...)
Show SMILES CC(C)Oc1ccc(F)c(c1)-c1ccc(cc1)C1CC(CC(O)=O)C1
Show InChI InChI=1S/C21H23FO3/c1-13(2)25-18-7-8-20(22)19(12-18)16-5-3-15(4-6-16)17-9-14(10-17)11-21(23)24/h3-8,12-14,17H,9-11H2,1-2H3,(H,23,24)
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n/an/an/an/a 210n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281707
PNG
(3-((2′-Fluoro-5′-isopropoxy-[1,1′...)
Show SMILES CC(C)Oc1ccc(F)c(c1)-c1ccc(C[C@H]2C[C@@H](C2)C(O)=O)cc1
Show InChI InChI=1S/C21H23FO3/c1-13(2)25-18-7-8-20(22)19(12-18)16-5-3-14(4-6-16)9-15-10-17(11-15)21(23)24/h3-8,12-13,15,17H,9-11H2,1-2H3,(H,23,24)/t15-,17-
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n/an/an/an/a 790n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281709
PNG
(2-(3-((2′-Fluoro-5′-isopropoxy-[1,1...)
Show SMILES CC(C)Oc1ccc(F)c(c1)-c1ccc(CC2CC(CC(O)=O)C2)cc1
Show InChI InChI=1S/C22H25FO3/c1-14(2)26-19-7-8-21(23)20(13-19)18-5-3-15(4-6-18)9-16-10-17(11-16)12-22(24)25/h3-8,13-14,16-17H,9-12H2,1-2H3,(H,24,25)
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n/an/an/an/a 650n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281717
PNG
(2-(3-(Cis-3-(3-phenoxyphenyl)cyclobutyl)propoxy)ac...)
Show SMILES OC(=O)COCCC[C@H]1C[C@H](C1)c1cccc(Oc2ccccc2)c1
Show InChI InChI=1S/C21H24O4/c22-21(23)15-24-11-5-6-16-12-18(13-16)17-7-4-10-20(14-17)25-19-8-2-1-3-9-19/h1-4,7-10,14,16,18H,5-6,11-13,15H2,(H,22,23)/t16-,18+
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n/an/an/an/a 420n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281719
PNG
(2-(3-(Cis-1-methyl-3-(3-phenoxyphenyl)cyclobutyl)p...)
Show SMILES C[C@@]1(CCCOCC(O)=O)C[C@@H](C1)c1cccc(Oc2ccccc2)c1
Show InChI InChI=1S/C22H26O4/c1-22(11-6-12-25-16-21(23)24)14-18(15-22)17-7-5-10-20(13-17)26-19-8-3-2-4-9-19/h2-5,7-10,13,18H,6,11-12,14-16H2,1H3,(H,23,24)/t18-,22+
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n/an/an/an/a 740n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281665
PNG
(US10023519, Example 6)
Show SMILES COc1cc(Cl)cc(c1)-c1ccc(cc1)[C@@H]1C[C@@H](C1)OCC(O)=O
Show InChI InChI=1S/C19H19ClO4/c1-23-17-7-14(6-16(20)10-17)12-2-4-13(5-3-12)15-8-18(9-15)24-11-19(21)22/h2-7,10,15,18H,8-9,11H2,1H3,(H,21,22)/t15-,18+
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n/an/an/an/a 880n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281680
PNG
(US10023519, Example 21)
Show SMILES Cc1nc(no1)-c1ccc(F)c(c1)-c1ccc(cc1)[C@@H]1C[C@@H](C1)OCC(O)=O
Show InChI InChI=1S/C21H19FN2O4/c1-12-23-21(24-28-12)15-6-7-19(22)18(10-15)14-4-2-13(3-5-14)16-8-17(9-16)27-11-20(25)26/h2-7,10,16-17H,8-9,11H2,1H3,(H,25,26)/t16-,17+
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n/an/an/an/a 550n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281705
PNG
(Cis-3-(3-(2′-fluoro-5′-isopropoxy-[1,1...)
Show SMILES CC(C)Oc1ccc(F)c(c1)-c1ccc(cc1)[C@@H]1C[C@H](CCC(O)=O)C1
Show InChI InChI=1S/C22H25FO3/c1-14(2)26-19-8-9-21(23)20(13-19)17-6-4-16(5-7-17)18-11-15(12-18)3-10-22(24)25/h4-9,13-15,18H,3,10-12H2,1-2H3,(H,24,25)/t15-,18+
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n/an/an/an/a 650n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281711
PNG
(US10023519, Example 52)
Show SMILES CC(C)Oc1ccc(F)c(c1)-c1ccc(C[C@H]2C[C@H](CC(O)=O)C2)cc1
Show InChI InChI=1S/C22H25FO3/c1-14(2)26-19-7-8-21(23)20(13-19)18-5-3-15(4-6-18)9-16-10-17(11-16)12-22(24)25/h3-8,13-14,16-17H,9-12H2,1-2H3,(H,24,25)/t16-,17-
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n/an/an/an/a 940n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281720
PNG
(2-(3-(Trans-1-methyl-3-(3-phenoxyphenyl)cyclobutyl...)
Show SMILES C[C@]1(CCCOCC(O)=O)C[C@@H](C1)c1cccc(Oc2ccccc2)c1
Show InChI InChI=1S/C22H26O4/c1-22(11-6-12-25-16-21(23)24)14-18(15-22)17-7-5-10-20(13-17)26-19-8-3-2-4-9-19/h2-5,7-10,13,18H,6,11-12,14-16H2,1H3,(H,23,24)/t18-,22-
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n/an/an/an/a 150n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281725
PNG
(Trans-2-(3-((2′-fluoro-5′-phenoxy-[1,1...)
Show SMILES OC(=O)C[C@H]1C[C@@H](C1)Oc1ccc(cc1)-c1cc(Oc2ccccc2)ccc1F
Show InChI InChI=1S/C24H21FO4/c25-23-11-10-20(28-18-4-2-1-3-5-18)15-22(23)17-6-8-19(9-7-17)29-21-12-16(13-21)14-24(26)27/h1-11,15-16,21H,12-14H2,(H,26,27)/t16-,21-
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n/an/an/an/a 110n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281726
PNG
(Cis-2-(3-((2′-fluoro-5′-phenoxy-[1,1&#...)
Show SMILES OC(=O)C[C@H]1C[C@H](C1)Oc1ccc(cc1)-c1cc(Oc2ccccc2)ccc1F
Show InChI InChI=1S/C24H21FO4/c25-23-11-10-20(28-18-4-2-1-3-5-18)15-22(23)17-6-8-19(9-7-17)29-21-12-16(13-21)14-24(26)27/h1-11,15-16,21H,12-14H2,(H,26,27)/t16-,21+
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n/an/an/an/a 330n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281727
PNG
(2-(3-(3-Methoxy-3-(3-phenoxyphenyl)cyclobutyl)prop...)
Show SMILES COC1(CC(CCCOCC(O)=O)C1)c1cccc(Oc2ccccc2)c1
Show InChI InChI=1S/C22H26O5/c1-25-22(14-17(15-22)7-6-12-26-16-21(23)24)18-8-5-11-20(13-18)27-19-9-3-2-4-10-19/h2-5,8-11,13,17H,6-7,12,14-16H2,1H3,(H,23,24)
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n/an/an/an/a 2.80E+3n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281660
PNG
(Cis-2-(-3-(2′-fluoro-5′-phenoxy-[1,1&#...)
Show SMILES OC(=O)CO[C@H]1C[C@H](C1)c1ccc(cc1)-c1cc(Oc2ccccc2)ccc1F
Show InChI InChI=1S/C24H21FO4/c25-23-11-10-20(29-19-4-2-1-3-5-19)14-22(23)17-8-6-16(7-9-17)18-12-21(13-18)28-15-24(26)27/h1-11,14,18,21H,12-13,15H2,(H,26,27)/t18-,21+
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n/an/an/an/a 170n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281662
PNG
(US10023519, Example 3)
Show SMILES OC(=O)CO[C@H]1C[C@H](C1)c1ccc(cc1)-c1cc(OC2CCCC2)ccc1F
Show InChI InChI=1S/C23H25FO4/c24-22-10-9-19(28-18-3-1-2-4-18)13-21(22)16-7-5-15(6-8-16)17-11-20(12-17)27-14-23(25)26/h5-10,13,17-18,20H,1-4,11-12,14H2,(H,25,26)/t17-,20+
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n/an/an/an/a 410n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281664
PNG
(US10023519, Example 5)
Show SMILES CC(C)Oc1cc(c(F)cn1)-c1ccc(cc1)[C@@H]1C[C@@H](C1)OCC(O)=O
Show InChI InChI=1S/C20H22FNO4/c1-12(2)26-19-9-17(18(21)10-22-19)14-5-3-13(4-6-14)15-7-16(8-15)25-11-20(23)24/h3-6,9-10,12,15-16H,7-8,11H2,1-2H3,(H,23,24)/t15-,16+
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n/an/an/an/a 2.07E+3n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281666
PNG
(US10023519, Example 7)
Show SMILES CC(C)Oc1cccc(c1)-c1ccc(cc1)[C@@H]1C[C@@H](C1)OCC(O)=O
Show InChI InChI=1S/C21H24O4/c1-14(2)25-19-5-3-4-17(10-19)15-6-8-16(9-7-15)18-11-20(12-18)24-13-21(22)23/h3-10,14,18,20H,11-13H2,1-2H3,(H,22,23)/t18-,20+
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n/an/an/an/a 590n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281684
PNG
(Cis-2-(3-(2′-fluoro-5′-(pyridin-4-ylox...)
Show SMILES OC(=O)CO[C@H]1C[C@H](C1)c1ccc(cc1)-c1cc(Oc2ccncc2)ccc1F
Show InChI InChI=1S/C23H20FNO4/c24-22-6-5-19(29-18-7-9-25-10-8-18)13-21(22)16-3-1-15(2-4-16)17-11-20(12-17)28-14-23(26)27/h1-10,13,17,20H,11-12,14H2,(H,26,27)/t17-,20+
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n/an/an/an/a 1.90E+3n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281695
PNG
(US10023519, Example 36)
Show SMILES OC(=O)CO[C@H]1C[C@H](C1)c1ccc(cc1)-c1cc(Oc2cccc(F)c2)cc(F)c1F
Show InChI InChI=1S/C24H19F3O4/c25-17-2-1-3-18(10-17)31-20-11-21(24(27)22(26)12-20)15-6-4-14(5-7-15)16-8-19(9-16)30-13-23(28)29/h1-7,10-12,16,19H,8-9,13H2,(H,28,29)/t16-,19+
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n/an/an/an/a 130n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 160


(Homo sapiens (Human))		BDBM281712
PNG
(4-(Cis-3-(3-phenoxybenzyloxy)cyclobutyl)butanoic a...)
Show SMILES OC(=O)CCC[C@H]1C[C@H](C1)OCc1cccc(Oc2ccccc2)c1
Show InChI InChI=1S/C21H24O4/c22-21(23)11-5-6-16-12-20(13-16)24-15-17-7-4-10-19(14-17)25-18-8-2-1-3-9-18/h1-4,7-10,14,16,20H,5-6,11-13,15H2,(H,22,23)/t16-,20+
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n/an/an/an/a 430n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were established using CHOA12 cells stably transfected with the short for...

US Patent US10023519 (2018)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%