Compile Data Set for Download or QSAR
maximum 50k data
Found 139 Enz. Inhib. hit(s) with all data for entry = 634
TargetRho-associated protein kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM50173310(CHEMBL3808660 | US10023564, Example 1)
Affinity DataIC50:  11nMAssay Description:Rho-associated coiled-coil kinase (ROCK) assays were performed with the ADP-Glo system using 0.1 μg ROCK1 and 1 μg S6K substrate, and 100 &...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM50173307(CHEMBL3809796 | US10023564, Example 8)
Affinity DataIC50:  17nMAssay Description:Rho-associated coiled-coil kinase (ROCK) assays were performed with the ADP-Glo system using 0.1 μg ROCK1 and 1 μg S6K substrate, and 100 &...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM50173315(CHEMBL3809100 | US10023564, Example 4)
Affinity DataIC50:  21nMAssay Description:Rho-associated coiled-coil kinase (ROCK) assays were performed with the ADP-Glo system using 0.1 μg ROCK1 and 1 μg S6K substrate, and 100 &...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM50173305(CHEMBL3810107 | US10023564, Example 3)
Affinity DataIC50:  23nMAssay Description:Rho-associated coiled-coil kinase (ROCK) assays were performed with the ADP-Glo system using 0.1 μg ROCK1 and 1 μg S6K substrate, and 100 &...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM50173311(CHEMBL3810073 | US10023564, Example 6)
Affinity DataIC50:  50nMAssay Description:Rho-associated coiled-coil kinase (ROCK) assays were performed with the ADP-Glo system using 0.1 μg ROCK1 and 1 μg S6K substrate, and 100 &...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM50173325(CHEMBL3809965 | US10023564, Example 5)
Affinity DataIC50:  57nMAssay Description:Rho-associated coiled-coil kinase (ROCK) assays were performed with the ADP-Glo system using 0.1 μg ROCK1 and 1 μg S6K substrate, and 100 &...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM50173325(CHEMBL3809965 | US10023564, Example 5)
Affinity DataIC50:  60nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM50173323(CHEMBL3808621 | US10023564, Example 2)
Affinity DataIC50:  61nMAssay Description:Rho-associated coiled-coil kinase (ROCK) assays were performed with the ADP-Glo system using 0.1 μg ROCK1 and 1 μg S6K substrate, and 100 &...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM50173314(CHEMBL3808840 | US10023564, Example 16)
Affinity DataIC50:  69nMAssay Description:Rho-associated coiled-coil kinase (ROCK) assays were performed with the ADP-Glo system using 0.1 μg ROCK1 and 1 μg S6K substrate, and 100 &...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRhodopsin kinase GRK1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM50173307(CHEMBL3809796 | US10023564, Example 8)
Affinity DataIC50:  70nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM50173309(CHEMBL3809913 | US10023564, Example 10)
Affinity DataIC50:  70nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM50173320(GSK-180736A | GSK180736A | US10023564, Compound GS...)
Affinity DataIC50:  78nMAssay Description:Rho-associated coiled-coil kinase (ROCK) assays were performed with the ADP-Glo system using 0.1 μg ROCK1 and 1 μg S6K substrate, and 100 &...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM50173312(CHEMBL3810312 | US10023564, Example 18)
Affinity DataIC50:  97nMAssay Description:Rho-associated coiled-coil kinase (ROCK) assays were performed with the ADP-Glo system using 0.1 μg ROCK1 and 1 μg S6K substrate, and 100 &...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM50173323(CHEMBL3808621 | US10023564, Example 2)
Affinity DataIC50:  120nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM50173319(CHEMBL3809020 | US10023564, Example 11)
Affinity DataIC50:  130nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM50173308(CHEMBL3810271 | US10023564, Example 9)
Affinity DataIC50:  130nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM283998(E24 | US10023564, Example 24)
Affinity DataIC50:  140nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM50173310(CHEMBL3808660 | US10023564, Example 1)
Affinity DataIC50:  150nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM50173329(CHEMBL3809697 | US10023564, Example 15)
Affinity DataIC50:  150nMAssay Description:Rho-associated coiled-coil kinase (ROCK) assays were performed with the ADP-Glo system using 0.1 μg ROCK1 and 1 μg S6K substrate, and 100 &...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM283996(E22 | US10023564, Example 22)
Affinity DataIC50:  180nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM50173317(CHEMBL3810349 | US10023564, Example 12)
Affinity DataIC50:  190nMAssay Description:Rho-associated coiled-coil kinase (ROCK) assays were performed with the ADP-Glo system using 0.1 μg ROCK1 and 1 μg S6K substrate, and 100 &...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM50173315(CHEMBL3809100 | US10023564, Example 4)
Affinity DataIC50:  200nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM50173324(CHEMBL3809124 | US10023564, Example 30)
Affinity DataIC50:  200nMAssay Description:Rho-associated coiled-coil kinase (ROCK) assays were performed with the ADP-Glo system using 0.1 μg ROCK1 and 1 μg S6K substrate, and 100 &...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM50173328(CHEMBL3808918 | US10023564, Example 14)
Affinity DataIC50:  230nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM283998(E24 | US10023564, Example 24)
Affinity DataIC50:  240nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM50173305(CHEMBL3810107 | US10023564, Example 3)
Affinity DataIC50:  280nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM50173328(CHEMBL3808918 | US10023564, Example 14)
Affinity DataIC50:  290nMAssay Description:Rho-associated coiled-coil kinase (ROCK) assays were performed with the ADP-Glo system using 0.1 μg ROCK1 and 1 μg S6K substrate, and 100 &...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM284001(E27 | US10023564, Example 27)
Affinity DataIC50:  320nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM50173310(CHEMBL3808660 | US10023564, Example 1)
Affinity DataIC50:  380nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM50173326(CHEMBL3809604 | US10023564, Example 29)
Affinity DataIC50:  400nMAssay Description:Rho-associated coiled-coil kinase (ROCK) assays were performed with the ADP-Glo system using 0.1 μg ROCK1 and 1 μg S6K substrate, and 100 &...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM283996(E22 | US10023564, Example 22)
Affinity DataIC50:  410nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM50173312(CHEMBL3810312 | US10023564, Example 18)
Affinity DataIC50:  420nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM50173324(CHEMBL3809124 | US10023564, Example 30)
Affinity DataIC50:  450nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM50173327(CHEMBL3808499 | US10023564, Example 28)
Affinity DataIC50:  450nMAssay Description:Rho-associated coiled-coil kinase (ROCK) assays were performed with the ADP-Glo system using 0.1 μg ROCK1 and 1 μg S6K substrate, and 100 &...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM50173311(CHEMBL3810073 | US10023564, Example 6)
Affinity DataIC50:  460nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM284006(E32 | US10023564, Example 32)
Affinity DataIC50:  500nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM284007(E33 | US10023564, Example 33)
Affinity DataIC50:  680nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM50173314(CHEMBL3808840 | US10023564, Example 16)
Affinity DataIC50:  690nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM283994(E20 | US10023564, Example 20)
Affinity DataIC50:  740nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM50173320(GSK-180736A | GSK180736A | US10023564, Compound GS...)
Affinity DataIC50:  770nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM50173315(CHEMBL3809100 | US10023564, Example 4)
Affinity DataIC50:  800nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM283997(E23 | US10023564, Example 23)
Affinity DataIC50:  820nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM284009(E35 | US10023564, Example 35)
Affinity DataIC50:  960nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM50173318(CHEMBL3809788 | US10023564, Example 17)
Affinity DataIC50:  1.20E+3nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM284000(E26 | US10023564, Example 26)
Affinity DataIC50:  1.20E+3nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM284008(E34 | US10023564, Example 34)
Affinity DataIC50:  1.20E+3nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM284005(E31 | US10023564, Example 31)
Affinity DataIC50:  1.50E+3nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM284006(E32 | US10023564, Example 32)
Affinity DataIC50:  1.70E+3nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM50173330(CHEMBL3808657 | US10023564, Example 13)
Affinity DataIC50:  1.90E+3nMAssay Description:Rho-associated coiled-coil kinase (ROCK) assays were performed with the ADP-Glo system using 0.1 μg ROCK1 and 1 μg S6K substrate, and 100 &...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM50173329(CHEMBL3809697 | US10023564, Example 15)
Affinity DataIC50:  1.90E+3nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
In DepthDetails US Patent
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