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Patent code US10028934

Compile Data Set for Download or QSAR
Found 74 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM239033
PNG
(US10028934, Compound 19 | US9408850, 19)
Show SMILES CN1CCC(CC1)Nc1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12
Show InChI InChI=1S/C29H33N5O3/c1-34-15-13-24(14-16-34)30-23-9-7-22(8-10-23)29(35)31-28-26-12-11-25(19-27(26)32-33-28)37-18-17-36-20-21-5-3-2-4-6-21/h2-12,19,24,30H,13-18,20H2,1H3,(H2,31,32,33,35)
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UniChem
n/an/a<50n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM239026
PNG
(US10028934, Compound 40 | US9408850, 40)
Show SMILES COc1ccc(COCCOc2ccc3c(NC(=O)c4ccc(cc4)N4CCN(C)CC4)n[nH]c3c2)cc1
Show InChI InChI=1S/C29H33N5O4/c1-33-13-15-34(16-14-33)23-7-5-22(6-8-23)29(35)30-28-26-12-11-25(19-27(26)31-32-28)38-18-17-37-20-21-3-9-24(36-2)10-4-21/h3-12,19H,13-18,20H2,1-2H3,(H2,30,31,32,35)
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n/an/a<50n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM239023
PNG
(US10028934, Compound 32 | US9408850, 32)
Show SMILES CN1CCN(CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCCOCc3ccc(F)cc3)ccc12
Show InChI InChI=1S/C28H30FN5O3/c1-33-12-14-34(15-13-33)23-8-4-21(5-9-23)28(35)30-27-25-11-10-24(18-26(25)31-32-27)37-17-16-36-19-20-2-6-22(29)7-3-20/h2-11,18H,12-17,19H2,1H3,(H2,30,31,32,35)
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n/an/a<50n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM239017
PNG
(US10028934, Compound 11 | US9408850, 11)
Show SMILES CN1CCN(CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12
Show InChI InChI=1S/C28H31N5O3/c1-32-13-15-33(16-14-32)23-9-7-22(8-10-23)28(34)29-27-25-12-11-24(19-26(25)30-31-27)36-18-17-35-20-21-5-3-2-4-6-21/h2-12,19H,13-18,20H2,1H3,(H2,29,30,31,34)
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n/an/a<50n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM239042
PNG
(US10028934, Compound 42 | US9408850, 42)
Show SMILES C[N+]1([O-])CCN(CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCCOCc3ccc(cc3)C(F)(F)F)ccc12
Show InChI InChI=1S/C29H30F3N5O4/c1-37(39)14-12-36(13-15-37)23-8-4-21(5-9-23)28(38)33-27-25-11-10-24(18-26(25)34-35-27)41-17-16-40-19-20-2-6-22(7-3-20)29(30,31)32/h2-11,18H,12-17,19H2,1H3,(H2,33,34,35,38)
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n/an/a<50n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM239023
PNG
(US10028934, Compound 32 | US9408850, 32)
Show SMILES CN1CCN(CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCCOCc3ccc(F)cc3)ccc12
Show InChI InChI=1S/C28H30FN5O3/c1-33-12-14-34(15-13-33)23-8-4-21(5-9-23)28(35)30-27-25-11-10-24(18-26(25)31-32-27)37-17-16-36-19-20-2-6-22(29)7-3-20/h2-11,18H,12-17,19H2,1H3,(H2,30,31,32,35)
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n/an/a 50n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM239038
PNG
(US10028934, Compound 27 | US9408850, 27)
Show SMILES CN1CCC(CNc2ccc(cc2)C(=O)Nc2n[nH]c3cc(OCCOCc4ccccc4)ccc23)CC1
Show InChI InChI=1S/C30H35N5O3/c1-35-15-13-22(14-16-35)20-31-25-9-7-24(8-10-25)30(36)32-29-27-12-11-26(19-28(27)33-34-29)38-18-17-37-21-23-5-3-2-4-6-23/h2-12,19,22,31H,13-18,20-21H2,1H3,(H2,32,33,34,36)
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n/an/a<50n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM239043
PNG
(US10028934, Compound 20 | US9408850, 20)
Show SMILES O=C(Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12)c1ccc(cc1)N1CCNCC1
Show InChI InChI=1S/C27H29N5O3/c33-27(21-6-8-22(9-7-21)32-14-12-28-13-15-32)29-26-24-11-10-23(18-25(24)30-31-26)35-17-16-34-19-20-4-2-1-3-5-20/h1-11,18,28H,12-17,19H2,(H2,29,30,31,33)
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n/an/a<50n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM239040
PNG
(US10028934, Compound 14 | US9408850, 14)
Show SMILES C[N+]1([O-])CCN(CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12
Show InChI InChI=1S/C28H31N5O4/c1-33(35)15-13-32(14-16-33)23-9-7-22(8-10-23)28(34)29-27-25-12-11-24(19-26(25)30-31-27)37-18-17-36-20-21-5-3-2-4-6-21/h2-12,19H,13-18,20H2,1H3,(H2,29,30,31,34)
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n/an/a<50n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM239034
PNG
(US10028934, Compound 23 | US9408850, 23)
Show SMILES CN(C1CCN(C)CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12
Show InChI InChI=1S/C30H35N5O3/c1-34-16-14-25(15-17-34)35(2)24-10-8-23(9-11-24)30(36)31-29-27-13-12-26(20-28(27)32-33-29)38-19-18-37-21-22-6-4-3-5-7-22/h3-13,20,25H,14-19,21H2,1-2H3,(H2,31,32,33,36)
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UniChem
n/an/a<50n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM239022
PNG
(US10028934, Compound 33 | US9408850, 33)
Show SMILES CN1CCN(CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCCOCc3ccc(cc3)C(F)(F)F)ccc12
Show InChI InChI=1S/C29H30F3N5O3/c1-36-12-14-37(15-13-36)23-8-4-21(5-9-23)28(38)33-27-25-11-10-24(18-26(25)34-35-27)40-17-16-39-19-20-2-6-22(7-3-20)29(30,31)32/h2-11,18H,12-17,19H2,1H3,(H2,33,34,35,38)
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n/an/a<50n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM239012
PNG
(US10028934, Compound 10 | US9408850, 10)
Show SMILES CN1CCN(CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCCOc3ccccc3)ccc12
Show InChI InChI=1S/C27H29N5O3/c1-31-13-15-32(16-14-31)21-9-7-20(8-10-21)27(33)28-26-24-12-11-23(19-25(24)29-30-26)35-18-17-34-22-5-3-2-4-6-22/h2-12,19H,13-18H2,1H3,(H2,28,29,30,33)
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n/an/a<50n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM239022
PNG
(US10028934, Compound 33 | US9408850, 33)
Show SMILES CN1CCN(CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCCOCc3ccc(cc3)C(F)(F)F)ccc12
Show InChI InChI=1S/C29H30F3N5O3/c1-36-12-14-37(15-13-36)23-8-4-21(5-9-23)28(38)33-27-25-11-10-24(18-26(25)34-35-27)40-17-16-39-19-20-2-6-22(7-3-20)29(30,31)32/h2-11,18H,12-17,19H2,1H3,(H2,33,34,35,38)
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UniChem
n/an/a 50n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM239029
PNG
(US10028934, Compound 15 | US9408850, 15)
Show SMILES CN(C)C1CCN(CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12
Show InChI InChI=1S/C30H35N5O3/c1-34(2)24-14-16-35(17-15-24)25-10-8-23(9-11-25)30(36)31-29-27-13-12-26(20-28(27)32-33-29)38-19-18-37-21-22-6-4-3-5-7-22/h3-13,20,24H,14-19,21H2,1-2H3,(H2,31,32,33,36)
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UniChem
n/an/a<50n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM239030
PNG
(US10028934, Compound 16 | US9408850, 16)
Show SMILES CN(C)CCN(C)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12
Show InChI InChI=1S/C28H33N5O3/c1-32(2)15-16-33(3)23-11-9-22(10-12-23)28(34)29-27-25-14-13-24(19-26(25)30-31-27)36-18-17-35-20-21-7-5-4-6-8-21/h4-14,19H,15-18,20H2,1-3H3,(H2,29,30,31,34)
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n/an/a<50n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM239041
PNG
(US10028934, Compound 41 | US9408850, 41)
Show SMILES CN(C1CC[N+](C)([O-])CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12
Show InChI InChI=1S/C30H35N5O4/c1-34(25-14-16-35(2,37)17-15-25)24-10-8-23(9-11-24)30(36)31-29-27-13-12-26(20-28(27)32-33-29)39-19-18-38-21-22-6-4-3-5-7-22/h3-13,20,25H,14-19,21H2,1-2H3,(H2,31,32,33,36)
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n/an/a 52n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM239043
PNG
(US10028934, Compound 20 | US9408850, 20)
Show SMILES O=C(Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12)c1ccc(cc1)N1CCNCC1
Show InChI InChI=1S/C27H29N5O3/c33-27(21-6-8-22(9-7-21)32-14-12-28-13-15-32)29-26-24-11-10-23(18-25(24)30-31-26)35-17-16-34-19-20-4-2-1-3-5-20/h1-11,18,28H,12-17,19H2,(H2,29,30,31,33)
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n/an/a 52n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM239019
PNG
(US10028934, Compound 22 | US9408850, 22)
Show SMILES CN1CCC(CC1)Oc1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12
Show InChI InChI=1S/C29H32N4O4/c1-33-15-13-24(14-16-33)37-23-9-7-22(8-10-23)29(34)30-28-26-12-11-25(19-27(26)31-32-28)36-18-17-35-20-21-5-3-2-4-6-21/h2-12,19,24H,13-18,20H2,1H3,(H2,30,31,32,34)
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PC sid
UniChem
n/an/a 55n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM239042
PNG
(US10028934, Compound 42 | US9408850, 42)
Show SMILES C[N+]1([O-])CCN(CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCCOCc3ccc(cc3)C(F)(F)F)ccc12
Show InChI InChI=1S/C29H30F3N5O4/c1-37(39)14-12-36(13-15-37)23-8-4-21(5-9-23)28(38)33-27-25-11-10-24(18-26(25)34-35-27)41-17-16-40-19-20-2-6-22(7-3-20)29(30,31)32/h2-11,18H,12-17,19H2,1H3,(H2,33,34,35,38)
UniProtKB/SwissProt

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PC cid
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UniChem
n/an/a 55n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM239019
PNG
(US10028934, Compound 22 | US9408850, 22)
Show SMILES CN1CCC(CC1)Oc1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12
Show InChI InChI=1S/C29H32N4O4/c1-33-15-13-24(14-16-33)37-23-9-7-22(8-10-23)29(34)30-28-26-12-11-25(19-27(26)31-32-28)36-18-17-35-20-21-5-3-2-4-6-21/h2-12,19,24H,13-18,20H2,1H3,(H2,30,31,32,34)
PDB
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n/an/a 56n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM239024
PNG
(US10028934, Compound 34 | US9408850, 34)
Show SMILES CN1CCN(CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCCOCc3cccc(c3)C(F)(F)F)ccc12
Show InChI InChI=1S/C29H30F3N5O3/c1-36-11-13-37(14-12-36)23-7-5-21(6-8-23)28(38)33-27-25-10-9-24(18-26(25)34-35-27)40-16-15-39-19-20-3-2-4-22(17-20)29(30,31)32/h2-10,17-18H,11-16,19H2,1H3,(H2,33,34,35,38)
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n/an/a 56n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM239024
PNG
(US10028934, Compound 34 | US9408850, 34)
Show SMILES CN1CCN(CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCCOCc3cccc(c3)C(F)(F)F)ccc12
Show InChI InChI=1S/C29H30F3N5O3/c1-36-11-13-37(14-12-36)23-7-5-21(6-8-23)28(38)33-27-25-10-9-24(18-26(25)34-35-27)40-16-15-39-19-20-3-2-4-22(17-20)29(30,31)32/h2-10,17-18H,11-16,19H2,1H3,(H2,33,34,35,38)
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n/an/a 58n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM239033
PNG
(US10028934, Compound 19 | US9408850, 19)
Show SMILES CN1CCC(CC1)Nc1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12
Show InChI InChI=1S/C29H33N5O3/c1-34-15-13-24(14-16-34)30-23-9-7-22(8-10-23)29(35)31-28-26-12-11-25(19-27(26)32-33-28)37-18-17-36-20-21-5-3-2-4-6-21/h2-12,19,24,30H,13-18,20H2,1H3,(H2,31,32,33,35)
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n/an/a 61n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM239028
PNG
(US10028934, Compound 39 | US9408850, 39)
Show SMILES CN1CCN(CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(OC\C=C\c3ccccc3)ccc12
Show InChI InChI=1S/C28H29N5O2/c1-32-15-17-33(18-16-32)23-11-9-22(10-12-23)28(34)29-27-25-14-13-24(20-26(25)30-31-27)35-19-5-8-21-6-3-2-4-7-21/h2-14,20H,15-19H2,1H3,(H2,29,30,31,34)/b8-5+
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n/an/a 62n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM239031
PNG
(US10028934, Compound 17 | US9408850, 17)
Show SMILES CN(C)CCCN(C)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12
Show InChI InChI=1S/C29H35N5O3/c1-33(2)16-7-17-34(3)24-12-10-23(11-13-24)29(35)30-28-26-15-14-25(20-27(26)31-32-28)37-19-18-36-21-22-8-5-4-6-9-22/h4-6,8-15,20H,7,16-19,21H2,1-3H3,(H2,30,31,32,35)
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n/an/a 62n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM239036
PNG
(US10028934, Compound 25 | US9408850, 25)
Show SMILES O=C(Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12)c1ccc(NCCN2CCOCC2)cc1
Show InChI InChI=1S/C29H33N5O4/c35-29(23-6-8-24(9-7-23)30-12-13-34-14-16-36-17-15-34)31-28-26-11-10-25(20-27(26)32-33-28)38-19-18-37-21-22-4-2-1-3-5-22/h1-11,20,30H,12-19,21H2,(H2,31,32,33,35)
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n/an/a 74n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM239029
PNG
(US10028934, Compound 15 | US9408850, 15)
Show SMILES CN(C)C1CCN(CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12
Show InChI InChI=1S/C30H35N5O3/c1-34(2)24-14-16-35(17-15-24)25-10-8-23(9-11-25)30(36)31-29-27-13-12-26(20-28(27)32-33-29)38-19-18-37-21-22-6-4-3-5-7-22/h3-13,20,24H,14-19,21H2,1-2H3,(H2,31,32,33,36)
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n/an/a 76n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM239026
PNG
(US10028934, Compound 40 | US9408850, 40)
Show SMILES COc1ccc(COCCOc2ccc3c(NC(=O)c4ccc(cc4)N4CCN(C)CC4)n[nH]c3c2)cc1
Show InChI InChI=1S/C29H33N5O4/c1-33-13-15-34(16-14-33)23-7-5-22(6-8-23)29(35)30-28-26-12-11-25(19-27(26)31-32-28)38-18-17-37-20-21-3-9-24(36-2)10-4-21/h3-12,19H,13-18,20H2,1-2H3,(H2,30,31,32,35)
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n/an/a 88n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM239037
PNG
(US10028934, Compound 26 | US9408850, 26)
Show SMILES O=C(Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12)c1ccc(NC2CCOCC2)cc1
Show InChI InChI=1S/C28H30N4O4/c33-28(21-6-8-22(9-7-21)29-23-12-14-34-15-13-23)30-27-25-11-10-24(18-26(25)31-32-27)36-17-16-35-19-20-4-2-1-3-5-20/h1-11,18,23,29H,12-17,19H2,(H2,30,31,32,33)
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NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM239038
PNG
(US10028934, Compound 27 | US9408850, 27)
Show SMILES CN1CCC(CNc2ccc(cc2)C(=O)Nc2n[nH]c3cc(OCCOCc4ccccc4)ccc23)CC1
Show InChI InChI=1S/C30H35N5O3/c1-35-15-13-22(14-16-35)20-31-25-9-7-24(8-10-25)30(36)32-29-27-12-11-26(19-28(27)33-34-29)38-18-17-37-21-23-5-3-2-4-6-23/h2-12,19,22,31H,13-18,20-21H2,1H3,(H2,32,33,34,36)
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NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM239018
PNG
(US10028934, Compound 21 | US9408850, 21)
Show SMILES CN(C)Cc1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12
Show InChI InChI=1S/C26H28N4O3/c1-30(2)17-19-8-10-21(11-9-19)26(31)27-25-23-13-12-22(16-24(23)28-29-25)33-15-14-32-18-20-6-4-3-5-7-20/h3-13,16H,14-15,17-18H2,1-2H3,(H2,27,28,29,31)
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n/an/a 104n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM239030
PNG
(US10028934, Compound 16 | US9408850, 16)
Show SMILES CN(C)CCN(C)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12
Show InChI InChI=1S/C28H33N5O3/c1-32(2)15-16-33(3)23-11-9-22(10-12-23)28(34)29-27-25-14-13-24(19-26(25)30-31-27)36-18-17-35-20-21-7-5-4-6-8-21/h4-14,19H,15-18,20H2,1-3H3,(H2,29,30,31,34)
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n/an/a 106n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM239034
PNG
(US10028934, Compound 23 | US9408850, 23)
Show SMILES CN(C1CCN(C)CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12
Show InChI InChI=1S/C30H35N5O3/c1-34-16-14-25(15-17-34)35(2)24-10-8-23(9-11-24)30(36)31-29-27-13-12-26(20-28(27)32-33-29)38-19-18-37-21-22-6-4-3-5-7-22/h3-13,20,25H,14-19,21H2,1-2H3,(H2,31,32,33,36)
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n/an/a 109n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM239017
PNG
(US10028934, Compound 11 | US9408850, 11)
Show SMILES CN1CCN(CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12
Show InChI InChI=1S/C28H31N5O3/c1-32-13-15-33(16-14-32)23-9-7-22(8-10-23)28(34)29-27-25-12-11-24(19-26(25)30-31-27)36-18-17-35-20-21-5-3-2-4-6-21/h2-12,19H,13-18,20H2,1H3,(H2,29,30,31,34)
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n/an/a 113n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM239040
PNG
(US10028934, Compound 14 | US9408850, 14)
Show SMILES C[N+]1([O-])CCN(CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12
Show InChI InChI=1S/C28H31N5O4/c1-33(35)15-13-32(14-16-33)23-9-7-22(8-10-23)28(34)29-27-25-12-11-24(19-26(25)30-31-27)37-18-17-36-20-21-5-3-2-4-6-21/h2-12,19H,13-18,20H2,1H3,(H2,29,30,31,34)
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n/an/a 118n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM239037
PNG
(US10028934, Compound 26 | US9408850, 26)
Show SMILES O=C(Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12)c1ccc(NC2CCOCC2)cc1
Show InChI InChI=1S/C28H30N4O4/c33-28(21-6-8-22(9-7-21)29-23-12-14-34-15-13-23)30-27-25-11-10-24(18-26(25)31-32-27)36-17-16-35-19-20-4-2-1-3-5-20/h1-11,18,23,29H,12-17,19H2,(H2,30,31,32,33)
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NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM239018
PNG
(US10028934, Compound 21 | US9408850, 21)
Show SMILES CN(C)Cc1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12
Show InChI InChI=1S/C26H28N4O3/c1-30(2)17-19-8-10-21(11-9-19)26(31)27-25-23-13-12-22(16-24(23)28-29-25)33-15-14-32-18-20-6-4-3-5-7-20/h3-13,16H,14-15,17-18H2,1-2H3,(H2,27,28,29,31)
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NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM239039
PNG
(US10028934, Compound 28 | US9408850, 28)
Show SMILES O=C(Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12)c1ccc(cc1)N1CC(C1)N1CCCC1
Show InChI InChI=1S/C30H33N5O3/c36-30(23-8-10-24(11-9-23)35-19-25(20-35)34-14-4-5-15-34)31-29-27-13-12-26(18-28(27)32-33-29)38-17-16-37-21-22-6-2-1-3-7-22/h1-3,6-13,18,25H,4-5,14-17,19-21H2,(H2,31,32,33,36)
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NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM239031
PNG
(US10028934, Compound 17 | US9408850, 17)
Show SMILES CN(C)CCCN(C)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12
Show InChI InChI=1S/C29H35N5O3/c1-33(2)16-7-17-34(3)24-12-10-23(11-13-24)29(35)30-28-26-15-14-25(20-27(26)31-32-28)37-19-18-36-21-22-8-5-4-6-9-22/h4-6,8-15,20H,7,16-19,21H2,1-3H3,(H2,30,31,32,35)
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NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM239035
PNG
(US10028934, Compound 24 | US9408850, 24)
Show SMILES O=C(Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12)c1ccc(cc1)N1CCOCC1
Show InChI InChI=1S/C27H28N4O4/c32-27(21-6-8-22(9-7-21)31-12-14-33-15-13-31)28-26-24-11-10-23(18-25(24)29-30-26)35-17-16-34-19-20-4-2-1-3-5-20/h1-11,18H,12-17,19H2,(H2,28,29,30,32)
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n/an/a 162n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM239025
PNG
(US10028934, Compound 30 | US9408850, 30)
Show SMILES CN1CCN(CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCCOCc3ccccc3F)ccc12
Show InChI InChI=1S/C28H30FN5O3/c1-33-12-14-34(15-13-33)22-8-6-20(7-9-22)28(35)30-27-24-11-10-23(18-26(24)31-32-27)37-17-16-36-19-21-4-2-3-5-25(21)29/h2-11,18H,12-17,19H2,1H3,(H2,30,31,32,35)
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n/an/a 166n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM239013
PNG
(US10028934, Compound 2 | US9408850, 2)
Show SMILES CN1CCN(CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(Oc3ccccc3)ccc12
Show InChI InChI=1S/C25H25N5O2/c1-29-13-15-30(16-14-29)19-9-7-18(8-10-19)25(31)26-24-22-12-11-21(17-23(22)27-28-24)32-20-5-3-2-4-6-20/h2-12,17H,13-16H2,1H3,(H2,26,27,28,31)
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n/an/a 172n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM239041
PNG
(US10028934, Compound 41 | US9408850, 41)
Show SMILES CN(C1CC[N+](C)([O-])CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12
Show InChI InChI=1S/C30H35N5O4/c1-34(25-14-16-35(2,37)17-15-25)24-10-8-23(9-11-24)30(36)31-29-27-13-12-26(20-28(27)32-33-29)39-19-18-38-21-22-6-4-3-5-7-22/h3-13,20,25H,14-19,21H2,1-2H3,(H2,31,32,33,36)
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n/an/a 180n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM239036
PNG
(US10028934, Compound 25 | US9408850, 25)
Show SMILES O=C(Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12)c1ccc(NCCN2CCOCC2)cc1
Show InChI InChI=1S/C29H33N5O4/c35-29(23-6-8-24(9-7-23)30-12-13-34-14-16-36-17-15-34)31-28-26-11-10-25(20-27(26)32-33-28)38-19-18-37-21-22-4-2-1-3-5-22/h1-11,20,30H,12-19,21H2,(H2,31,32,33,35)
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n/an/a 197n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM239011
PNG
(US10028934, Compound 6 | US9408850, 6)
Show SMILES CN1CCN(CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(OC3CCN(Cc4ccccc4)CC3)ccc12
Show InChI InChI=1S/C31H36N6O2/c1-35-17-19-37(20-18-35)25-9-7-24(8-10-25)31(38)32-30-28-12-11-27(21-29(28)33-34-30)39-26-13-15-36(16-14-26)22-23-5-3-2-4-6-23/h2-12,21,26H,13-20,22H2,1H3,(H2,32,33,34,38)
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n/an/a 248n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM239010
PNG
(US10028934, Compound 7 | US9408850, 7)
Show SMILES CN1CCN(CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCC#Cc3ccccc3)ccc12
Show InChI InChI=1S/C28H27N5O2/c1-32-15-17-33(18-16-32)23-11-9-22(10-12-23)28(34)29-27-25-14-13-24(20-26(25)30-31-27)35-19-5-8-21-6-3-2-4-7-21/h2-4,6-7,9-14,20H,15-19H2,1H3,(H2,29,30,31,34)
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n/an/a 249n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM239035
PNG
(US10028934, Compound 24 | US9408850, 24)
Show SMILES O=C(Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12)c1ccc(cc1)N1CCOCC1
Show InChI InChI=1S/C27H28N4O4/c32-27(21-6-8-22(9-7-21)31-12-14-33-15-13-31)28-26-24-11-10-23(18-25(24)29-30-26)35-17-16-34-19-20-4-2-1-3-5-20/h1-11,18H,12-17,19H2,(H2,28,29,30,32)
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n/an/a 260n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM239039
PNG
(US10028934, Compound 28 | US9408850, 28)
Show SMILES O=C(Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12)c1ccc(cc1)N1CC(C1)N1CCCC1
Show InChI InChI=1S/C30H33N5O3/c36-30(23-8-10-24(11-9-23)35-19-25(20-35)34-14-4-5-15-34)31-29-27-13-12-26(18-28(27)32-33-29)38-17-16-37-21-22-6-2-1-3-7-22/h1-3,6-13,18,25H,4-5,14-17,19-21H2,(H2,31,32,33,36)
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n/an/a 306n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM239032
PNG
(US10028934, Compound 18 | US9408850, 18)
Show SMILES CC(C)(C)OC(=O)N1CCN(CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12
Show InChI InChI=1S/C32H37N5O5/c1-32(2,3)42-31(39)37-17-15-36(16-18-37)25-11-9-24(10-12-25)30(38)33-29-27-14-13-26(21-28(27)34-35-29)41-20-19-40-22-23-7-5-4-6-8-23/h4-14,21H,15-20,22H2,1-3H3,(H2,33,34,35,38)
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n/an/a 414n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM239009
PNG
(US10028934, Compound 1 | US9408850, 1)
Show SMILES CN1CCN(CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCc3ccccc3)ccc12
Show InChI InChI=1S/C26H27N5O2/c1-30-13-15-31(16-14-30)21-9-7-20(8-10-21)26(32)27-25-23-12-11-22(17-24(23)28-29-25)33-18-19-5-3-2-4-6-19/h2-12,17H,13-16,18H2,1H3,(H2,27,28,29,32)
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n/an/a 428n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM239028
PNG
(US10028934, Compound 39 | US9408850, 39)
Show SMILES CN1CCN(CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(OC\C=C\c3ccccc3)ccc12
Show InChI InChI=1S/C28H29N5O2/c1-32-15-17-33(18-16-32)23-11-9-22(10-12-23)28(34)29-27-25-14-13-24(20-26(25)30-31-27)35-19-5-8-21-6-3-2-4-7-21/h2-14,20H,15-19H2,1H3,(H2,29,30,31,34)/b8-5+
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n/an/a 528n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM239021
PNG
(US10028934, Compound 38 | US9408850, 38)
Show SMILES CN1CCN(CC1)c1ccc(C(=O)Nc2n[nH]c3cc(OCCOCc4ccccc4)ccc23)c(F)c1
Show InChI InChI=1S/C28H30FN5O3/c1-33-11-13-34(14-12-33)21-7-9-23(25(29)17-21)28(35)30-27-24-10-8-22(18-26(24)31-32-27)37-16-15-36-19-20-5-3-2-4-6-20/h2-10,17-18H,11-16,19H2,1H3,(H2,30,31,32,35)
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n/an/a 539n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM239014
PNG
(US10028934, Compound 3 | US9408850, 3)
Show SMILES CN1CCN(CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(Oc3cccc(F)c3)ccc12
Show InChI InChI=1S/C25H24FN5O2/c1-30-11-13-31(14-12-30)19-7-5-17(6-8-19)25(32)27-24-22-10-9-21(16-23(22)28-29-24)33-20-4-2-3-18(26)15-20/h2-10,15-16H,11-14H2,1H3,(H2,27,28,29,32)
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n/an/a 564n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM239021
PNG
(US10028934, Compound 38 | US9408850, 38)
Show SMILES CN1CCN(CC1)c1ccc(C(=O)Nc2n[nH]c3cc(OCCOCc4ccccc4)ccc23)c(F)c1
Show InChI InChI=1S/C28H30FN5O3/c1-33-11-13-34(14-12-33)21-7-9-23(25(29)17-21)28(35)30-27-24-10-8-22(18-26(24)31-32-27)37-16-15-36-19-20-5-3-2-4-6-20/h2-10,17-18H,11-16,19H2,1H3,(H2,30,31,32,35)
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n/an/a 613n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM239020
PNG
(US10028934, Compound 29 | US9408850, 29)
Show SMILES CN1CCN(CC1)c1cccc(c1)C(=O)Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12
Show InChI InChI=1S/C28H31N5O3/c1-32-12-14-33(15-13-32)23-9-5-8-22(18-23)28(34)29-27-25-11-10-24(19-26(25)30-31-27)36-17-16-35-20-21-6-3-2-4-7-21/h2-11,18-19H,12-17,20H2,1H3,(H2,29,30,31,34)
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n/an/a 635n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM239014
PNG
(US10028934, Compound 3 | US9408850, 3)
Show SMILES CN1CCN(CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(Oc3cccc(F)c3)ccc12
Show InChI InChI=1S/C25H24FN5O2/c1-30-11-13-31(14-12-30)19-7-5-17(6-8-19)25(32)27-24-22-10-9-21(16-23(22)28-29-24)33-20-4-2-3-18(26)15-20/h2-10,15-16H,11-14H2,1H3,(H2,27,28,29,32)
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n/an/a 639n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM239016
PNG
(US10028934, Compound 9 | US9408850, 9)
Show SMILES CN1CCN(CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(Oc3cccc(OCc4ccccc4)c3)ccc12
Show InChI InChI=1S/C32H31N5O3/c1-36-16-18-37(19-17-36)25-12-10-24(11-13-25)32(38)33-31-29-15-14-28(21-30(29)34-35-31)40-27-9-5-8-26(20-27)39-22-23-6-3-2-4-7-23/h2-15,20-21H,16-19,22H2,1H3,(H2,33,34,35,38)
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n/an/a 713n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM239012
PNG
(US10028934, Compound 10 | US9408850, 10)
Show SMILES CN1CCN(CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCCOc3ccccc3)ccc12
Show InChI InChI=1S/C27H29N5O3/c1-31-13-15-32(16-14-31)21-9-7-20(8-10-21)27(33)28-26-24-12-11-23(19-25(24)29-30-26)35-18-17-34-22-5-3-2-4-6-22/h2-12,19H,13-18H2,1H3,(H2,28,29,30,33)
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n/an/a 956n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM239015
PNG
(US10028934, Compound 4 | US9408850, 4)
Show SMILES CN1CCN(CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(Oc3ccc(OCc4ccccc4)cc3)ccc12
Show InChI InChI=1S/C32H31N5O3/c1-36-17-19-37(20-18-36)25-9-7-24(8-10-25)32(38)33-31-29-16-15-28(21-30(29)34-35-31)40-27-13-11-26(12-14-27)39-22-23-5-3-2-4-6-23/h2-16,21H,17-20,22H2,1H3,(H2,33,34,35,38)
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n/an/a 974n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM239020
PNG
(US10028934, Compound 29 | US9408850, 29)
Show SMILES CN1CCN(CC1)c1cccc(c1)C(=O)Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12
Show InChI InChI=1S/C28H31N5O3/c1-32-12-14-33(15-13-32)23-9-5-8-22(18-23)28(34)29-27-25-11-10-24(19-26(25)30-31-27)36-17-16-35-20-21-6-3-2-4-7-21/h2-11,18-19H,12-17,20H2,1H3,(H2,29,30,31,34)
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n/an/a 1.08E+3n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM239013
PNG
(US10028934, Compound 2 | US9408850, 2)
Show SMILES CN1CCN(CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(Oc3ccccc3)ccc12
Show InChI InChI=1S/C25H25N5O2/c1-29-13-15-30(16-14-29)19-9-7-18(8-10-19)25(31)26-24-22-12-11-21(17-23(22)27-28-24)32-20-5-3-2-4-6-20/h2-12,17H,13-16H2,1H3,(H2,26,27,28,31)
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UniChem
n/an/a 1.13E+3n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM239008
PNG
(US10028934, Compound 5 | US9408850, 5)
Show SMILES CN1CCN(CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCc3cccc(Oc4ccccc4)c3)ccc12
Show InChI InChI=1S/C32H31N5O3/c1-36-16-18-37(19-17-36)25-12-10-24(11-13-25)32(38)33-31-29-15-14-27(21-30(29)34-35-31)39-22-23-6-5-9-28(20-23)40-26-7-3-2-4-8-26/h2-15,20-21H,16-19,22H2,1H3,(H2,33,34,35,38)
PDB
MMDB

KEGG

UniProtKB/SwissProt

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PC sid
UniChem
n/an/a 1.17E+3n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM239027
PNG
(US10028934, Compound 35 | US9408850, 35)
Show SMILES CN1CCN(CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCCOCc3ccncc3)ccc12
Show InChI InChI=1S/C27H30N6O3/c1-32-12-14-33(15-13-32)22-4-2-21(3-5-22)27(34)29-26-24-7-6-23(18-25(24)30-31-26)36-17-16-35-19-20-8-10-28-11-9-20/h2-11,18H,12-17,19H2,1H3,(H2,29,30,31,34)
PDB
MMDB

KEGG

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PC sid
UniChem
n/an/a 1.18E+3n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM239032
PNG
(US10028934, Compound 18 | US9408850, 18)
Show SMILES CC(C)(C)OC(=O)N1CCN(CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12
Show InChI InChI=1S/C32H37N5O5/c1-32(2,3)42-31(39)37-17-15-36(16-18-37)25-11-9-24(10-12-25)30(38)33-29-27-14-13-26(21-28(27)34-35-29)41-20-19-40-22-23-7-5-4-6-8-23/h4-14,21H,15-20,22H2,1-3H3,(H2,33,34,35,38)
UniProtKB/SwissProt

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UniChem
n/an/a 1.39E+3n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM239025
PNG
(US10028934, Compound 30 | US9408850, 30)
Show SMILES CN1CCN(CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCCOCc3ccccc3F)ccc12
Show InChI InChI=1S/C28H30FN5O3/c1-33-12-14-34(15-13-33)22-8-6-20(7-9-22)28(35)30-27-24-11-10-23(18-26(24)31-32-27)37-17-16-36-19-21-4-2-3-5-25(21)29/h2-11,18H,12-17,19H2,1H3,(H2,30,31,32,35)
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UniChem
n/an/a 1.41E+3n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM239016
PNG
(US10028934, Compound 9 | US9408850, 9)
Show SMILES CN1CCN(CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(Oc3cccc(OCc4ccccc4)c3)ccc12
Show InChI InChI=1S/C32H31N5O3/c1-36-16-18-37(19-17-36)25-12-10-24(11-13-25)32(38)33-31-29-15-14-28(21-30(29)34-35-31)40-27-9-5-8-26(20-27)39-22-23-6-3-2-4-7-23/h2-15,20-21H,16-19,22H2,1H3,(H2,33,34,35,38)
PDB
MMDB

KEGG

UniProtKB/SwissProt

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UniChem
n/an/a 1.50E+3n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM239010
PNG
(US10028934, Compound 7 | US9408850, 7)
Show SMILES CN1CCN(CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCC#Cc3ccccc3)ccc12
Show InChI InChI=1S/C28H27N5O2/c1-32-15-17-33(18-16-32)23-11-9-22(10-12-23)28(34)29-27-25-14-13-24(20-26(25)30-31-27)35-19-5-8-21-6-3-2-4-7-21/h2-4,6-7,9-14,20H,15-19H2,1H3,(H2,29,30,31,34)
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UniChem
n/an/a 1.51E+3n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM239027
PNG
(US10028934, Compound 35 | US9408850, 35)
Show SMILES CN1CCN(CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCCOCc3ccncc3)ccc12
Show InChI InChI=1S/C27H30N6O3/c1-32-12-14-33(15-13-32)22-4-2-21(3-5-22)27(34)29-26-24-7-6-23(18-25(24)30-31-26)36-17-16-35-19-20-8-10-28-11-9-20/h2-11,18H,12-17,19H2,1H3,(H2,29,30,31,34)
UniProtKB/SwissProt

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UniChem
n/an/a 2.37E+3n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM239008
PNG
(US10028934, Compound 5 | US9408850, 5)
Show SMILES CN1CCN(CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCc3cccc(Oc4ccccc4)c3)ccc12
Show InChI InChI=1S/C32H31N5O3/c1-36-16-18-37(19-17-36)25-12-10-24(11-13-25)32(38)33-31-29-15-14-27(21-30(29)34-35-31)39-22-23-6-5-9-28(20-23)40-26-7-3-2-4-8-26/h2-15,20-21H,16-19,22H2,1H3,(H2,33,34,35,38)
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UniChem
n/an/a 2.62E+3n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM239009
PNG
(US10028934, Compound 1 | US9408850, 1)
Show SMILES CN1CCN(CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCc3ccccc3)ccc12
Show InChI InChI=1S/C26H27N5O2/c1-30-13-15-31(16-14-30)21-9-7-20(8-10-21)26(32)27-25-23-12-11-22(17-24(23)28-29-25)33-18-19-5-3-2-4-6-19/h2-12,17H,13-16,18H2,1H3,(H2,27,28,29,32)
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UniChem
n/an/a 2.81E+3n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM279845
PNG
(US10028934, Ref. Compound)
Show SMILES CN(C)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12
PDB
MMDB

KEGG

UniProtKB/SwissProt

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n/an/a 3.18E+3n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM239011
PNG
(US10028934, Compound 6 | US9408850, 6)
Show SMILES CN1CCN(CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(OC3CCN(Cc4ccccc4)CC3)ccc12
Show InChI InChI=1S/C31H36N6O2/c1-35-17-19-37(20-18-35)25-9-7-24(8-10-25)31(38)32-30-28-12-11-27(21-29(28)33-34-30)39-26-13-15-36(16-14-26)22-23-5-3-2-4-6-23/h2-12,21,26H,13-20,22H2,1H3,(H2,32,33,34,38)
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UniChem
n/an/a 6.89E+3n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM239015
PNG
(US10028934, Compound 4 | US9408850, 4)
Show SMILES CN1CCN(CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(Oc3ccc(OCc4ccccc4)cc3)ccc12
Show InChI InChI=1S/C32H31N5O3/c1-36-17-19-37(20-18-36)25-9-7-24(8-10-25)32(38)33-31-29-16-15-28(21-30(29)34-35-31)40-27-13-11-26(12-14-27)39-22-23-5-3-2-4-6-23/h2-16,21H,17-20,22H2,1H3,(H2,33,34,35,38)
UniProtKB/SwissProt

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UniChem
n/an/a>1.00E+4n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM279845
PNG
(US10028934, Ref. Compound)
Show SMILES CN(C)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12
UniProtKB/SwissProt

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n/an/a>1.00E+4n/an/an/an/an/an/a



NERVIANO MEDICAL SCIENCES S.R.L.

US Patent


Assay Description
i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...


US Patent US10028934 (2018)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%