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Patent code US10030026

Compile Data Set for Download or QSAR
Found 52 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutamate [NMDA] receptor


(Homo sapiens)
BDBM280730
PNG
(US10030026, Compound C-12)
Show SMILES FC(F)Oc1ccc(nc1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12
PDB
MMDB

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n/an/a 23n/an/an/an/an/an/a



Rugen Holdings (Cayman) Limited

US Patent


Assay Description
HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...


US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor


(Homo sapiens)
BDBM280739
PNG
(US10030026, Compound LX-1)
Show SMILES FC(F)(F)c1ccc(cc1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12
PDB
MMDB

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n/an/a 24n/an/an/an/an/an/a



Rugen Holdings (Cayman) Limited

US Patent


Assay Description
HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...


US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor


(Homo sapiens)
BDBM280739
PNG
(US10030026, Compound LX-1)
Show SMILES FC(F)(F)c1ccc(cc1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12
PDB
MMDB

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n/an/a 24n/an/an/an/an/an/a



Rugen Holdings (Cayman) Limited

US Patent


Assay Description
HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...


US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor


(Homo sapiens)
BDBM280724
PNG
(US10030026, Compound C-3)
Show SMILES FC(F)(CN1CCC(CC1)Nc1ncnc2[nH]ncc12)c1ccc(Cl)cn1
PDB
MMDB

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Rugen Holdings (Cayman) Limited

US Patent


Assay Description
HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...


US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor


(Homo sapiens)
BDBM280729
PNG
(US10030026, Compound C-11)
Show SMILES FC(F)(F)Oc1ccc(nc1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12
PDB
MMDB

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n/an/a 28n/an/an/an/an/an/a



Rugen Holdings (Cayman) Limited

US Patent


Assay Description
HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...


US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor


(Homo sapiens)
BDBM280732
PNG
(US10030026, Compound C-16)
Show SMILES Fc1cc(Cl)cnc1C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12
PDB
MMDB

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Rugen Holdings (Cayman) Limited

US Patent


Assay Description
HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...


US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor


(Homo sapiens)
BDBM280732
PNG
(US10030026, Compound C-16)
Show SMILES Fc1cc(Cl)cnc1C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12
PDB
MMDB

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Rugen Holdings (Cayman) Limited

US Patent


Assay Description
HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...


US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor


(Homo sapiens)
BDBM280732
PNG
(US10030026, Compound C-16)
Show SMILES Fc1cc(Cl)cnc1C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12
PDB
MMDB

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Rugen Holdings (Cayman) Limited

US Patent


Assay Description
HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...


US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor


(Homo sapiens)
BDBM280726
PNG
(US10030026, Compound C-5)
Show SMILES FC(F)(F)c1ccc(nc1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12
PDB
MMDB

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Rugen Holdings (Cayman) Limited

US Patent


Assay Description
HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...


US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor


(Homo sapiens)
BDBM280726
PNG
(US10030026, Compound C-5)
Show SMILES FC(F)(F)c1ccc(nc1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12
PDB
MMDB

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n/an/a 32n/an/an/an/an/an/a



Rugen Holdings (Cayman) Limited

US Patent


Assay Description
HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...


US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor


(Homo sapiens)
BDBM280727
PNG
(US10030026, Compound C-6)
Show SMILES FC(F)c1ccc(nc1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12
PDB
MMDB

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n/an/a 34n/an/an/an/an/an/a



Rugen Holdings (Cayman) Limited

US Patent


Assay Description
HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...


US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor


(Homo sapiens)
BDBM280737
PNG
(US10030026, Compound C-127)
Show SMILES FC(F)(F)c1ccc(cn1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12
PDB
MMDB

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n/an/a 38n/an/an/an/an/an/a



Rugen Holdings (Cayman) Limited

US Patent


Assay Description
HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...


US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor


(Homo sapiens)
BDBM280737
PNG
(US10030026, Compound C-127)
Show SMILES FC(F)(F)c1ccc(cn1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12
PDB
MMDB

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n/an/a 38n/an/an/an/an/an/a



Rugen Holdings (Cayman) Limited

US Patent


Assay Description
HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...


US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor


(Homo sapiens)
BDBM280737
PNG
(US10030026, Compound C-127)
Show SMILES FC(F)(F)c1ccc(cn1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12
PDB
MMDB

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Rugen Holdings (Cayman) Limited

US Patent


Assay Description
HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...


US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor


(Homo sapiens)
BDBM280728
PNG
(US10030026, Compound C-7)
Show SMILES FCc1ccc(nc1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12
PDB
MMDB

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Rugen Holdings (Cayman) Limited

US Patent


Assay Description
HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...


US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor


(Homo sapiens)
BDBM280733
PNG
(US10030026, Compound C-17)
Show SMILES Cc1cnc(c(F)c1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12
PDB
MMDB

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Rugen Holdings (Cayman) Limited

US Patent


Assay Description
HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...


US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor


(Homo sapiens)
BDBM280725
PNG
(US10030026, Compound C-4)
Show SMILES Cc1ccc(nc1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12
PDB
MMDB

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Rugen Holdings (Cayman) Limited

US Patent


Assay Description
HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...


US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor


(Homo sapiens)
BDBM280735
PNG
(US10030026, Compound C-24)
Show SMILES FC(F)(CN1CCC(CC1)Nc1ncnc2[nH]ncc12)c1ncc(Cl)cc1Cl
PDB
MMDB

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Rugen Holdings (Cayman) Limited

US Patent


Assay Description
HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...


US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor


(Homo sapiens)
BDBM280734
PNG
(US10030026, Compound C-18)
Show SMILES Fc1cc(cnc1C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12)C(F)(F)F
PDB
MMDB

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Rugen Holdings (Cayman) Limited

US Patent


Assay Description
HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...


US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor


(Homo sapiens)
BDBM280734
PNG
(US10030026, Compound C-18)
Show SMILES Fc1cc(cnc1C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12)C(F)(F)F
PDB
MMDB

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Rugen Holdings (Cayman) Limited

US Patent


Assay Description
HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...


US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor


(Homo sapiens)
BDBM280734
PNG
(US10030026, Compound C-18)
Show SMILES Fc1cc(cnc1C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12)C(F)(F)F
PDB
MMDB

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Rugen Holdings (Cayman) Limited

US Patent


Assay Description
HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...


US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor


(Homo sapiens)
BDBM280738
PNG
(US10030026, Compound C-142)
Show SMILES Cc1n[nH]c2ncnc(NC3CCN(CC(F)(F)c4ccc(nc4)C(F)(F)F)CC3)c12
PDB
MMDB

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n/an/a 89n/an/an/an/an/an/a



Rugen Holdings (Cayman) Limited

US Patent


Assay Description
HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...


US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor


(Homo sapiens)
BDBM280736
PNG
(US10030026, Compound C-33)
Show SMILES Cc1n[nH]c2ncnc(NC3CCN(CC(F)(F)c4ccc(cn4)C(F)(F)F)CC3)c12
PDB
MMDB

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Rugen Holdings (Cayman) Limited

US Patent


Assay Description
HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...


US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor


(Homo sapiens)
BDBM280731
PNG
(US10030026, Compound C-15)
Show SMILES Fc1cnc(c(F)c1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12
PDB
MMDB

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Rugen Holdings (Cayman) Limited

US Patent


Assay Description
HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...


US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor


(Homo sapiens)
BDBM280736
PNG
(US10030026, Compound C-33)
Show SMILES Cc1n[nH]c2ncnc(NC3CCN(CC(F)(F)c4ccc(cn4)C(F)(F)F)CC3)c12
PDB
MMDB

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Rugen Holdings (Cayman) Limited

US Patent


Assay Description
HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...


US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor


(Homo sapiens)
BDBM280723
PNG
(N-(1-(2,2-difluoro-2-(pyridin-2-yl)ethyl)piperidin...)
Show SMILES FC(F)(CN1CCC(CC1)Nc1ncnc2[nH]ncc12)c1ccccn1
PDB
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Rugen Holdings (Cayman) Limited

US Patent


Assay Description
HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...


US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Voltage-gated potassium channel


(Homo sapiens (human))
BDBM280739
PNG
(US10030026, Compound LX-1)
Show SMILES FC(F)(F)c1ccc(cc1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12
PDB
MMDB

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n/an/a 1.00E+3n/an/an/an/an/an/a



Rugen Holdings (Cayman) Limited

US Patent


Assay Description
Inhibitory activities of test compounds on 5 major isoforms of CYP P450 were evaluated by using pooled human liver microsome (HLM, purchased from BD ...


US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Voltage-gated potassium channel


(Homo sapiens (human))
BDBM280737
PNG
(US10030026, Compound C-127)
Show SMILES FC(F)(F)c1ccc(cn1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12
PDB
MMDB

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n/an/a 2.40E+3n/an/an/an/an/an/a



Rugen Holdings (Cayman) Limited

US Patent


Assay Description
Inhibitory activities of test compounds on 5 major isoforms of CYP P450 were evaluated by using pooled human liver microsome (HLM, purchased from BD ...


US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Voltage-gated potassium channel


(Homo sapiens (human))
BDBM280739
PNG
(US10030026, Compound LX-1)
Show SMILES FC(F)(F)c1ccc(cc1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12
PDB
MMDB

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n/an/a 4.50E+3n/an/an/an/an/an/a



Rugen Holdings (Cayman) Limited

US Patent


Assay Description
The assay was performed on hERG channel stably expressed in HEK293 cells. The cells were cultured at 37 C. in a humidified CO2 incubator in the grow...


US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Voltage-gated potassium channel


(Homo sapiens (human))
BDBM280732
PNG
(US10030026, Compound C-16)
Show SMILES Fc1cc(Cl)cnc1C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12
PDB
MMDB

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n/an/a 1.00E+4n/an/an/an/an/an/a



Rugen Holdings (Cayman) Limited

US Patent


Assay Description
Inhibitory activities of test compounds on 5 major isoforms of CYP P450 were evaluated by using pooled human liver microsome (HLM, purchased from BD ...


US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Voltage-gated potassium channel


(Homo sapiens (human))
BDBM280734
PNG
(US10030026, Compound C-18)
Show SMILES Fc1cc(cnc1C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12)C(F)(F)F
PDB
MMDB

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n/an/a 1.15E+4n/an/an/an/an/an/a



Rugen Holdings (Cayman) Limited

US Patent


Assay Description
Inhibitory activities of test compounds on 5 major isoforms of CYP P450 were evaluated by using pooled human liver microsome (HLM, purchased from BD ...


US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Voltage-gated potassium channel


(Homo sapiens (human))
BDBM280734
PNG
(US10030026, Compound C-18)
Show SMILES Fc1cc(cnc1C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12)C(F)(F)F
PDB
MMDB

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n/an/a 1.20E+4n/an/an/an/an/an/a



Rugen Holdings (Cayman) Limited

US Patent


Assay Description
The assay was performed on hERG channel stably expressed in HEK293 cells. The cells were cultured at 37 C. in a humidified CO2 incubator in the grow...


US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Voltage-gated potassium channel


(Homo sapiens (human))
BDBM280732
PNG
(US10030026, Compound C-16)
Show SMILES Fc1cc(Cl)cnc1C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12
PDB
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n/an/a 1.30E+4n/an/an/an/an/an/a



Rugen Holdings (Cayman) Limited

US Patent


Assay Description
The assay was performed on hERG channel stably expressed in HEK293 cells. The cells were cultured at 37 C. in a humidified CO2 incubator in the grow...


US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Voltage-gated potassium channel


(Homo sapiens (human))
BDBM280737
PNG
(US10030026, Compound C-127)
Show SMILES FC(F)(F)c1ccc(cn1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12
PDB
MMDB

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n/an/a 2.30E+4n/an/an/an/an/an/a



Rugen Holdings (Cayman) Limited

US Patent


Assay Description
The assay was performed on hERG channel stably expressed in HEK293 cells. The cells were cultured at 37 C. in a humidified CO2 incubator in the grow...


US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Voltage-gated potassium channel


(Homo sapiens (human))
BDBM280736
PNG
(US10030026, Compound C-33)
Show SMILES Cc1n[nH]c2ncnc(NC3CCN(CC(F)(F)c4ccc(cn4)C(F)(F)F)CC3)c12
PDB
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n/an/a>3.00E+4n/an/an/an/an/an/a



Rugen Holdings (Cayman) Limited

US Patent


Assay Description
The assay was performed on hERG channel stably expressed in HEK293 cells. The cells were cultured at 37 C. in a humidified CO2 incubator in the grow...


US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Voltage-gated potassium channel


(Homo sapiens (human))
BDBM280726
PNG
(US10030026, Compound C-5)
Show SMILES FC(F)(F)c1ccc(nc1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12
PDB
MMDB

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n/an/a 3.10E+4n/an/an/an/an/an/a



Rugen Holdings (Cayman) Limited

US Patent


Assay Description
The assay was performed on hERG channel stably expressed in HEK293 cells. The cells were cultured at 37 C. in a humidified CO2 incubator in the grow...


US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor


(Homo sapiens)
BDBM280727
PNG
(US10030026, Compound C-6)
Show SMILES FC(F)c1ccc(nc1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12
PDB
MMDB

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n/an/a>1.00E+7n/an/an/an/an/an/a



Rugen Holdings (Cayman) Limited

US Patent




US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor


(Homo sapiens)
BDBM280728
PNG
(US10030026, Compound C-7)
Show SMILES FCc1ccc(nc1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12
PDB
MMDB

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n/an/a>1.00E+7n/an/an/an/an/an/a



Rugen Holdings (Cayman) Limited

US Patent




US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor


(Homo sapiens)
BDBM280723
PNG
(N-(1-(2,2-difluoro-2-(pyridin-2-yl)ethyl)piperidin...)
Show SMILES FC(F)(CN1CCC(CC1)Nc1ncnc2[nH]ncc12)c1ccccn1
PDB
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n/an/a>1.00E+7n/an/an/an/an/an/a



Rugen Holdings (Cayman) Limited

US Patent




US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor


(Homo sapiens)
BDBM280725
PNG
(US10030026, Compound C-4)
Show SMILES Cc1ccc(nc1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12
PDB
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n/an/a>1.00E+7n/an/an/an/an/an/a



Rugen Holdings (Cayman) Limited

US Patent




US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor


(Homo sapiens)
BDBM280736
PNG
(US10030026, Compound C-33)
Show SMILES Cc1n[nH]c2ncnc(NC3CCN(CC(F)(F)c4ccc(cn4)C(F)(F)F)CC3)c12
PDB
MMDB

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Rugen Holdings (Cayman) Limited

US Patent




US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor


(Homo sapiens)
BDBM280732
PNG
(US10030026, Compound C-16)
Show SMILES Fc1cc(Cl)cnc1C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12
PDB
MMDB

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n/an/a>1.00E+7n/an/an/an/an/an/a



Rugen Holdings (Cayman) Limited

US Patent




US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor


(Homo sapiens)
BDBM280730
PNG
(US10030026, Compound C-12)
Show SMILES FC(F)Oc1ccc(nc1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12
PDB
MMDB

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Rugen Holdings (Cayman) Limited

US Patent




US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor


(Homo sapiens)
BDBM280731
PNG
(US10030026, Compound C-15)
Show SMILES Fc1cnc(c(F)c1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12
PDB
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n/an/a>1.00E+7n/an/an/an/an/an/a



Rugen Holdings (Cayman) Limited

US Patent




US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor


(Homo sapiens)
BDBM280734
PNG
(US10030026, Compound C-18)
Show SMILES Fc1cc(cnc1C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12)C(F)(F)F
PDB
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n/an/a>1.00E+7n/an/an/an/an/an/a



Rugen Holdings (Cayman) Limited

US Patent




US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor


(Homo sapiens)
BDBM280738
PNG
(US10030026, Compound C-142)
Show SMILES Cc1n[nH]c2ncnc(NC3CCN(CC(F)(F)c4ccc(nc4)C(F)(F)F)CC3)c12
PDB
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Rugen Holdings (Cayman) Limited

US Patent




US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor


(Homo sapiens)
BDBM280726
PNG
(US10030026, Compound C-5)
Show SMILES FC(F)(F)c1ccc(nc1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12
PDB
MMDB

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Rugen Holdings (Cayman) Limited

US Patent




US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor


(Homo sapiens)
BDBM280737
PNG
(US10030026, Compound C-127)
Show SMILES FC(F)(F)c1ccc(cn1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12
PDB
MMDB

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Rugen Holdings (Cayman) Limited

US Patent




US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor


(Homo sapiens)
BDBM280735
PNG
(US10030026, Compound C-24)
Show SMILES FC(F)(CN1CCC(CC1)Nc1ncnc2[nH]ncc12)c1ncc(Cl)cc1Cl
PDB
MMDB

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Rugen Holdings (Cayman) Limited

US Patent




US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor


(Homo sapiens)
BDBM280724
PNG
(US10030026, Compound C-3)
Show SMILES FC(F)(CN1CCC(CC1)Nc1ncnc2[nH]ncc12)c1ccc(Cl)cn1
PDB
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Rugen Holdings (Cayman) Limited

US Patent




US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor


(Homo sapiens)
BDBM280729
PNG
(US10030026, Compound C-11)
Show SMILES FC(F)(F)Oc1ccc(nc1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12
PDB
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Rugen Holdings (Cayman) Limited

US Patent




US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor


(Homo sapiens)
BDBM280733
PNG
(US10030026, Compound C-17)
Show SMILES Cc1cnc(c(F)c1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ncc12
PDB
MMDB

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Rugen Holdings (Cayman) Limited

US Patent




US Patent US10030026 (2018)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%