BindingDB logo
myBDB logout

Patent code US10047097

Compile Data Set for Download or QSAR
Found 105 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136642
PNG
(US10047097, 59 | US8865698, 59 | US9676783, 59)
Show SMILES Fc1ccc(F)c(c1)[C@H]1CCCN1c1ccn2ncc(NC(=O)c3ccccn3)c2n1
Show InChI InChI=1S/C22H18F2N6O/c23-14-6-7-16(24)15(12-14)19-5-3-10-29(19)20-8-11-30-21(28-20)18(13-26-30)27-22(31)17-4-1-2-9-25-17/h1-2,4,6-9,11-13,19H,3,5,10H2,(H,27,31)/t19-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 1.70n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136646
PNG
(US10047097, 63 | US8865698, 63 | US9676783, 63)
Show SMILES Cc1cccnc1C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F
Show InChI InChI=1S/C23H20F2N6O/c1-14-4-2-9-26-21(14)23(32)28-18-13-27-31-11-8-20(29-22(18)31)30-10-3-5-19(30)16-12-15(24)6-7-17(16)25/h2,4,6-9,11-13,19H,3,5,10H2,1H3,(H,28,32)/t19-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 1.70n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136640
PNG
(US10047097, 57 | US8865698, 57 | US9676783, 57)
Show SMILES Fc1ccc(F)c(c1)[C@H]1CCCN1c1ccn2ncc(NC(=O)c3cnccn3)c2n1
Show InChI InChI=1S/C21H17F2N7O/c22-13-3-4-15(23)14(10-13)18-2-1-8-29(18)19-5-9-30-20(28-19)16(12-26-30)27-21(31)17-11-24-6-7-25-17/h3-7,9-12,18H,1-2,8H2,(H,27,31)/t18-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 2.20n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136650
PNG
(US10047097, 67 | US8865698, 67 | US9676783, 67)
Show SMILES Fc1ccc(F)c(c1)[C@H]1CCCN1c1ccn2ncc(NC(=O)c3ncccn3)c2n1
Show InChI InChI=1S/C21H17F2N7O/c22-13-4-5-15(23)14(11-13)17-3-1-9-29(17)18-6-10-30-20(28-18)16(12-26-30)27-21(31)19-24-7-2-8-25-19/h2,4-8,10-12,17H,1,3,9H2,(H,27,31)/t17-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 3n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136641
PNG
(US10047097, 58 | US8865698, 58 | US9676783, 58)
Show SMILES Cc1cnc(cn1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F
Show InChI InChI=1S/C22H19F2N7O/c1-13-10-26-18(11-25-13)22(32)28-17-12-27-31-8-6-20(29-21(17)31)30-7-2-3-19(30)15-9-14(23)4-5-16(15)24/h4-6,8-12,19H,2-3,7H2,1H3,(H,28,32)/t19-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 3.10n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136638
PNG
(US10047097, 55 | US8865698, 55 | US9676783, 55)
Show SMILES CC(C)Nc1nc(cs1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F
Show InChI InChI=1S/C23H23F2N7OS/c1-13(2)27-23-29-18(12-34-23)22(33)28-17-11-26-32-9-7-20(30-21(17)32)31-8-3-4-19(31)15-10-14(24)5-6-16(15)25/h5-7,9-13,19H,3-4,8H2,1-2H3,(H,27,29)(H,28,33)/t19-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
US Patent
n/an/a 3.10n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136667
PNG
(US10047097, 84 | US8865698, 84 | US9676783, 84)
Show SMILES O[C@H]1CCN(C1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1C(F)(F)F
Show InChI InChI=1S/C22H22F4N6O2/c23-13-3-4-16(22(24,25)26)15(10-13)18-2-1-7-31(18)19-6-9-32-20(29-19)17(11-27-32)28-21(34)30-8-5-14(33)12-30/h3-4,6,9-11,14,18,33H,1-2,5,7-8,12H2,(H,28,34)/t14-,18+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 3.20n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136654
PNG
(US10047097, 71 | US8865698, 71 | US9676783, 71)
Show SMILES Fc1ccc(F)c(c1)[C@H]1CCCN1c1ccn2ncc(NC(=O)c3cccc(Cl)n3)c2n1
Show InChI InChI=1S/C22H17ClF2N6O/c23-19-5-1-3-16(27-19)22(32)28-17-12-26-31-10-8-20(29-21(17)31)30-9-2-4-18(30)14-11-13(24)6-7-15(14)25/h1,3,5-8,10-12,18H,2,4,9H2,(H,28,32)/t18-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 3.5n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136645
PNG
(US10047097, 62 | US8865698, 62 | US9676783, 62)
Show SMILES Fc1ccc(F)c(c1)[C@H]1CCCN1c1ccn2ncc(NC(=O)c3cc(Cl)ccn3)c2n1
Show InChI InChI=1S/C22H17ClF2N6O/c23-13-5-7-26-17(10-13)22(32)28-18-12-27-31-9-6-20(29-21(18)31)30-8-1-2-19(30)15-11-14(24)3-4-16(15)25/h3-7,9-12,19H,1-2,8H2,(H,28,32)/t19-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 4n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136644
PNG
(US10047097, 61 | US8865698, 61 | US9676783, 61)
Show SMILES Fc1ccc(F)c(c1)[C@H]1CCCN1c1ccn2ncc(NC(=O)c3ccc(Cl)cn3)c2n1
Show InChI InChI=1S/C22H17ClF2N6O/c23-13-3-6-17(26-11-13)22(32)28-18-12-27-31-9-7-20(29-21(18)31)30-8-1-2-19(30)15-10-14(24)4-5-16(15)25/h3-7,9-12,19H,1-2,8H2,(H,28,32)/t19-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 4n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136651
PNG
(US10047097, 68 | US8865698, 68 | US9676783, 68)
Show SMILES Fc1cccc(c1)[C@H]1CCCN1c1ccn2ncc(NC(=O)c3ccccn3)c2n1
Show InChI InChI=1S/C22H19FN6O/c23-16-6-3-5-15(13-16)19-8-4-11-28(19)20-9-12-29-21(27-20)18(14-25-29)26-22(30)17-7-1-2-10-24-17/h1-3,5-7,9-10,12-14,19H,4,8,11H2,(H,26,30)/t19-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 4n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136624
PNG
(US10047097, 41 | US8865698, 41 | US9676783, 41)
Show SMILES O[C@@H]1CCN(C1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1Cl
Show InChI InChI=1S/C21H22ClFN6O2/c22-16-4-3-13(23)10-15(16)18-2-1-7-28(18)19-6-9-29-20(26-19)17(11-24-29)25-21(31)27-8-5-14(30)12-27/h3-4,6,9-11,14,18,30H,1-2,5,7-8,12H2,(H,25,31)/t14-,18-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 4.10n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136635
PNG
(US10047097, 52 | US8865698, 52 | US9676783, 52)
Show SMILES Fc1ccc(F)c(c1)[C@H]1CCCN1c1ccn2ncc(NC(=O)C3(CC3)C#N)c2n1
Show InChI InChI=1S/C21H18F2N6O/c22-13-3-4-15(23)14(10-13)17-2-1-8-28(17)18-5-9-29-19(27-18)16(11-25-29)26-20(30)21(12-24)6-7-21/h3-5,9-11,17H,1-2,6-8H2,(H,26,30)/t17-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 4.20n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136643
PNG
(US10047097, 60 | US8865698, 60 | US9676783, 60)
Show SMILES Cc1cccc(n1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F
Show InChI InChI=1S/C23H20F2N6O/c1-14-4-2-5-18(27-14)23(32)28-19-13-26-31-11-9-21(29-22(19)31)30-10-3-6-20(30)16-12-15(24)7-8-17(16)25/h2,4-5,7-9,11-13,20H,3,6,10H2,1H3,(H,28,32)/t20-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 4.20n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136601
PNG
(US10047097, 18 | US8865698, 18 | US9676783, 18)
Show SMILES Fc1ccc(NC(=O)Nc2cnn3ccc(nc23)N2CCC[C@@H]2c2cc(F)ccc2F)cc1
Show InChI InChI=1S/C23H19F3N6O/c24-14-3-6-16(7-4-14)28-23(33)29-19-13-27-32-11-9-21(30-22(19)32)31-10-1-2-20(31)17-12-15(25)5-8-18(17)26/h3-9,11-13,20H,1-2,10H2,(H2,28,29,33)/t20-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 4.60n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136682
PNG
(US10047097, 99 | US8865698, 99 | US9676783, 99)
Show SMILES NC(=O)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F
Show InChI InChI=1S/C18H16F2N6O2/c19-10-3-4-12(20)11(8-10)14-2-1-6-25(14)15-5-7-26-17(24-15)13(9-22-26)23-18(28)16(21)27/h3-5,7-9,14H,1-2,6H2,(H2,21,27)(H,23,28)/t14-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 4.65n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136688
PNG
(US10047097, 105 | US8865698, 105 | US9676783, 105)
Show SMILES OC(=O)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F
Show InChI InChI=1S/C18H15F2N5O3/c19-10-3-4-12(20)11(8-10)14-2-1-6-24(14)15-5-7-25-16(23-15)13(9-21-25)22-17(26)18(27)28/h3-5,7-9,14H,1-2,6H2,(H,22,26)(H,27,28)/t14-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 4.70n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136616
PNG
(US10047097, 33 | US8865698, 33 | US9676783, 33)
Show SMILES COC(=O)C1(CC1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F
Show InChI InChI=1S/C22H21F2N5O3/c1-32-21(31)22(7-8-22)20(30)26-16-12-25-29-10-6-18(27-19(16)29)28-9-2-3-17(28)14-11-13(23)4-5-15(14)24/h4-6,10-12,17H,2-3,7-9H2,1H3,(H,26,30)/t17-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 4.70n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136603
PNG
(US10047097, 20 | US8865698, 20 | US9676783, 20)
Show SMILES COc1ccc(NC(=O)Nc2cnn3ccc(nc23)N2CCC[C@@H]2c2cc(F)ccc2F)cc1
Show InChI InChI=1S/C24H22F2N6O2/c1-34-17-7-5-16(6-8-17)28-24(33)29-20-14-27-32-12-10-22(30-23(20)32)31-11-2-3-21(31)18-13-15(25)4-9-19(18)26/h4-10,12-14,21H,2-3,11H2,1H3,(H2,28,29,33)/t21-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 4.80n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136587
PNG
(US10047097, 4 | US8865698, 4 | US9676783, 4)
Show SMILES Fc1ccc(F)c(c1)[C@H]1CCCN1c1ccn2ncc(NC(=O)Nc3ccccc3)c2n1
Show InChI InChI=1S/C23H20F2N6O/c24-15-8-9-18(25)17(13-15)20-7-4-11-30(20)21-10-12-31-22(29-21)19(14-26-31)28-23(32)27-16-5-2-1-3-6-16/h1-3,5-6,8-10,12-14,20H,4,7,11H2,(H2,27,28,32)/t20-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 5n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136634
PNG
(US10047097, 51 | US8865698, 51 | US9676783, 51)
Show SMILES Fc1ccc(F)c(c1)[C@H]1CCCN1c1ccn2ncc(NC(=O)C3(CC3)C(F)(F)F)c2n1
Show InChI InChI=1S/C21H18F5N5O/c22-12-3-4-14(23)13(10-12)16-2-1-8-30(16)17-5-9-31-18(29-17)15(11-27-31)28-19(32)20(6-7-20)21(24,25)26/h3-5,9-11,16H,1-2,6-8H2,(H,28,32)/t16-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 5.20n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136662
PNG
(US10047097, 79 | US8865698, 79 | US9676783, 79)
Show SMILES COc1ncccc1C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cccc(F)c1
Show InChI InChI=1S/C23H21FN6O2/c1-32-23-17(7-3-10-25-23)22(31)27-18-14-26-30-12-9-20(28-21(18)30)29-11-4-8-19(29)15-5-2-6-16(24)13-15/h2-3,5-7,9-10,12-14,19H,4,8,11H2,1H3,(H,27,31)/t19-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 5.70n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136668
PNG
(US10047097, 85 | US8865698, 85 | US9676783, 85)
Show SMILES O[C@@H]1CCN(C1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1C(F)(F)F
Show InChI InChI=1S/C22H22F4N6O2/c23-13-3-4-16(22(24,25)26)15(10-13)18-2-1-7-31(18)19-6-9-32-20(29-19)17(11-27-32)28-21(34)30-8-5-14(33)12-30/h3-4,6,9-11,14,18,33H,1-2,5,7-8,12H2,(H,28,34)/t14-,18-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 5.70n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136652
PNG
(US10047097, 69 | US8865698, 69 | US9676783, 69)
Show SMILES Cc1cccnc1C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cccc(F)c1
Show InChI InChI=1S/C23H21FN6O/c1-15-5-3-10-25-21(15)23(31)27-18-14-26-30-12-9-20(28-22(18)30)29-11-4-8-19(29)16-6-2-7-17(24)13-16/h2-3,5-7,9-10,12-14,19H,4,8,11H2,1H3,(H,27,31)/t19-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 6.20n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136628
PNG
(US10047097, 45 | US8865698, 45 | US9676783, 45)
Show SMILES CC(C)(C)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F
Show InChI InChI=1S/C21H23F2N5O/c1-21(2,3)20(29)25-16-12-24-28-10-8-18(26-19(16)28)27-9-4-5-17(27)14-11-13(22)6-7-15(14)23/h6-8,10-12,17H,4-5,9H2,1-3H3,(H,25,29)/t17-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 6.30n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136665
PNG
(US10047097, 82 | US8865698, 82 | US9676783, 82)
Show SMILES Cc1cnc(cn1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cccc(F)c1
Show InChI InChI=1S/C22H20FN7O/c1-14-11-25-18(12-24-14)22(31)27-17-13-26-30-9-7-20(28-21(17)30)29-8-3-6-19(29)15-4-2-5-16(23)10-15/h2,4-5,7,9-13,19H,3,6,8H2,1H3,(H,27,31)/t19-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 6.60n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136658
PNG
(US10047097, 75 | US8865698, 75 | US9676783, 75)
Show SMILES COc1cccc(n1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cccc(F)c1
Show InChI InChI=1S/C23H21FN6O2/c1-32-21-9-3-7-17(26-21)23(31)27-18-14-25-30-12-10-20(28-22(18)30)29-11-4-8-19(29)15-5-2-6-16(24)13-15/h2-3,5-7,9-10,12-14,19H,4,8,11H2,1H3,(H,27,31)/t19-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 7.40n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136647
PNG
(US10047097, 64 | US8865698, 64 | US9676783, 64)
Show SMILES CC(C)(CO)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F
Show InChI InChI=1S/C21H23F2N5O2/c1-21(2,12-29)20(30)25-16-11-24-28-9-7-18(26-19(16)28)27-8-3-4-17(27)14-10-13(22)5-6-15(14)23/h5-7,9-11,17,29H,3-4,8,12H2,1-2H3,(H,25,30)/t17-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 7.5n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136687
PNG
(US10047097, 104 | US8865698, 104 | US9676783, 104)
Show SMILES COC(=O)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F
Show InChI InChI=1S/C19H17F2N5O3/c1-29-19(28)18(27)23-14-10-22-26-8-6-16(24-17(14)26)25-7-2-3-15(25)12-9-11(20)4-5-13(12)21/h4-6,8-10,15H,2-3,7H2,1H3,(H,23,27)/t15-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 7.65n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136681
PNG
(US10047097, 98 | US8865698, 98 | US9676783, 98)
Show SMILES CNC(=O)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F
Show InChI InChI=1S/C19H18F2N6O2/c1-22-18(28)19(29)24-14-10-23-27-8-6-16(25-17(14)27)26-7-2-3-15(26)12-9-11(20)4-5-13(12)21/h4-6,8-10,15H,2-3,7H2,1H3,(H,22,28)(H,24,29)/t15-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 7.65n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136664
PNG
(US10047097, 81 | US8865698, 81 | US9676783, 81)
Show SMILES O[C@H]1CCN(C1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1Cl
Show InChI InChI=1S/C21H22ClFN6O2/c22-16-4-3-13(23)10-15(16)18-2-1-7-28(18)19-6-9-29-20(26-19)17(11-24-29)25-21(31)27-8-5-14(30)12-27/h3-4,6,9-11,14,18,30H,1-2,5,7-8,12H2,(H,25,31)/t14-,18+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 8n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136656
PNG
(US10047097, 73 | US8865698, 73 | US9676783, 73)
Show SMILES Cn1ccc(n1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cccc(F)c1
Show InChI InChI=1S/C21H20FN7O/c1-27-10-7-16(26-27)21(30)24-17-13-23-29-11-8-19(25-20(17)29)28-9-3-6-18(28)14-4-2-5-15(22)12-14/h2,4-5,7-8,10-13,18H,3,6,9H2,1H3,(H,24,30)/t18-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 8.5n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136620
PNG
(US10047097, 37 | US8865698, 37 | US9676783, 37)
Show SMILES O[C@H]1CCN(C1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1C(F)F
Show InChI InChI=1S/C22H23F3N6O2/c23-13-3-4-15(20(24)25)16(10-13)18-2-1-7-30(18)19-6-9-31-21(28-19)17(11-26-31)27-22(33)29-8-5-14(32)12-29/h3-4,6,9-11,14,18,20,32H,1-2,5,7-8,12H2,(H,27,33)/t14-,18+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 8.70n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136597
PNG
(US10047097, 14 | US8865698, 14 | US9676783, 14)
Show SMILES O[C@H]1CCN(C1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F
Show InChI InChI=1S/C21H22F2N6O2/c22-13-3-4-16(23)15(10-13)18-2-1-7-28(18)19-6-9-29-20(26-19)17(11-24-29)25-21(31)27-8-5-14(30)12-27/h3-4,6,9-11,14,18,30H,1-2,5,7-8,12H2,(H,25,31)/t14-,18+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 9.70n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136684
PNG
(US10047097, 101 | US8865698, 101 | US9676783, 101)
Show SMILES OC1CN(C1)C(=O)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F
Show InChI InChI=1S/C21H20F2N6O3/c22-12-3-4-15(23)14(8-12)17-2-1-6-28(17)18-5-7-29-19(26-18)16(9-24-29)25-20(31)21(32)27-10-13(30)11-27/h3-5,7-9,13,17,30H,1-2,6,10-11H2,(H,25,31)/t17-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 10.1n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136602
PNG
(US10047097, 19 | US8865698, 19 | US9676783, 19)
Show SMILES Fc1ccc(F)c(c1)[C@H]1CCCN1c1ccn2ncc(NC(=O)Nc3ccc(Cl)cc3)c2n1
Show InChI InChI=1S/C23H19ClF2N6O/c24-14-3-6-16(7-4-14)28-23(33)29-19-13-27-32-11-9-21(30-22(19)32)31-10-1-2-20(31)17-12-15(25)5-8-18(17)26/h3-9,11-13,20H,1-2,10H2,(H2,28,29,33)/t20-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 10.1n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136674
PNG
(US10047097, 91 | US8865698, 91 | US9676783, 91)
Show SMILES COc1ccc(F)cc1[C@H]1CCCN1c1ccn2ncc(NC(=O)N3CCC[C@H](O)C3)c2n1
Show InChI InChI=1S/C23H27FN6O3/c1-33-20-7-6-15(24)12-17(20)19-5-3-10-29(19)21-8-11-30-22(27-21)18(13-25-30)26-23(32)28-9-2-4-16(31)14-28/h6-8,11-13,16,19,31H,2-5,9-10,14H2,1H3,(H,26,32)/t16-,19+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 10.2n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136673
PNG
(US10047097, 90 | US8865698, 90 | US9676783, 90)
Show SMILES COc1ccc(F)cc1[C@H]1CCCN1c1ccn2ncc(NC(=O)N3CC[C@H](O)C3)c2n1
Show InChI InChI=1S/C22H25FN6O3/c1-32-19-5-4-14(23)11-16(19)18-3-2-8-28(18)20-7-10-29-21(26-20)17(12-24-29)25-22(31)27-9-6-15(30)13-27/h4-5,7,10-12,15,18,30H,2-3,6,8-9,13H2,1H3,(H,25,31)/t15-,18+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 11.3n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136605
PNG
(US10047097, 22 | US8865698, 22 | US9676783, 22)
Show SMILES CC1(O)CN(C1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1Cl
Show InChI InChI=1S/C21H22ClFN6O2/c1-21(31)11-27(12-21)20(30)25-16-10-24-29-8-6-18(26-19(16)29)28-7-2-3-17(28)14-9-13(23)4-5-15(14)22/h4-6,8-10,17,31H,2-3,7,11-12H2,1H3,(H,25,30)/t17-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 11.5n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136626
PNG
(US10047097, 43 | US8865698, 43 | US9676783, 43)
Show SMILES O[C@@H]1CCCN(C1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1Cl
Show InChI InChI=1S/C22H24ClFN6O2/c23-17-6-5-14(24)11-16(17)19-4-2-9-29(19)20-7-10-30-21(27-20)18(12-25-30)26-22(32)28-8-1-3-15(31)13-28/h5-7,10-12,15,19,31H,1-4,8-9,13H2,(H,26,32)/t15-,19-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 11.7n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136588
PNG
(US10047097, 5 | US8865698, 5 | US9676783, 5)
Show SMILES CC(C)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F
Show InChI InChI=1S/C20H21F2N5O/c1-12(2)20(28)24-16-11-23-27-9-7-18(25-19(16)27)26-8-3-4-17(26)14-10-13(21)5-6-15(14)22/h5-7,9-12,17H,3-4,8H2,1-2H3,(H,24,28)/t17-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 12.1n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136633
PNG
(US10047097, 50 | US8865698, 50 | US9676783, 50)
Show SMILES CC(C)(O)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F
Show InChI InChI=1S/C20H21F2N5O2/c1-20(2,29)19(28)24-15-11-23-27-9-7-17(25-18(15)27)26-8-3-4-16(26)13-10-12(21)5-6-14(13)22/h5-7,9-11,16,29H,3-4,8H2,1-2H3,(H,24,28)/t16-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 12.4n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136685
PNG
(US10047097, 102 | US8865698, 102 | US9676783, 102)
Show SMILES O[C@H]1CCN(C1)C(=O)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F
Show InChI InChI=1S/C22H22F2N6O3/c23-13-3-4-16(24)15(10-13)18-2-1-7-29(18)19-6-9-30-20(27-19)17(11-25-30)26-21(32)22(33)28-8-5-14(31)12-28/h3-4,6,9-11,14,18,31H,1-2,5,7-8,12H2,(H,26,32)/t14-,18+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 12.8n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136598
PNG
(US10047097, 15 | US8865698, 15)
Show SMILES O[C@@H]1CN(C[C@H]1O)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F
Show InChI InChI=1S/C21H22F2N6O3/c22-12-3-4-14(23)13(8-12)16-2-1-6-28(16)19-5-7-29-20(26-19)15(9-24-29)25-21(32)27-10-17(30)18(31)11-27/h3-5,7-9,16-18,30-31H,1-2,6,10-11H2,(H,25,32)/t16-,17-,18-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 13.3n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136627
PNG
(US10047097, 44 | US8865698, 44 | US9676783, 44)
Show SMILES O[C@H]1CCCN(C1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1Cl
Show InChI InChI=1S/C22H24ClFN6O2/c23-17-6-5-14(24)11-16(17)19-4-2-9-29(19)20-7-10-30-21(27-20)18(12-25-30)26-22(32)28-8-1-3-15(31)13-28/h5-7,10-12,15,19,31H,1-4,8-9,13H2,(H,26,32)/t15-,19+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 13.4n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136591
PNG
(US10047097, 8 | US8865698, 8 | US9676783, 8)
Show SMILES OC1CN(C1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1Cl
Show InChI InChI=1S/C20H20ClFN6O2/c21-15-4-3-12(22)8-14(15)17-2-1-6-27(17)18-5-7-28-19(25-18)16(9-23-28)24-20(30)26-10-13(29)11-26/h3-5,7-9,13,17,29H,1-2,6,10-11H2,(H,24,30)/t17-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 13.7n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136669
PNG
(US10047097, 86 | US8865698, 86 | US9676783, 86)
Show SMILES O[C@@H]1CCCN(C1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1C(F)(F)F
Show InChI InChI=1S/C23H24F4N6O2/c24-14-5-6-17(23(25,26)27)16(11-14)19-4-2-9-32(19)20-7-10-33-21(30-20)18(12-28-33)29-22(35)31-8-1-3-15(34)13-31/h5-7,10-12,15,19,34H,1-4,8-9,13H2,(H,29,35)/t15-,19-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 14n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136637
PNG
(US10047097, 54 | US8865698, 54 | US9676783, 54)
Show SMILES CC(C)(F)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F
Show InChI InChI=1S/C20H20F3N5O/c1-20(2,23)19(29)25-15-11-24-28-9-7-17(26-18(15)28)27-8-3-4-16(27)13-10-12(21)5-6-14(13)22/h5-7,9-11,16H,3-4,8H2,1-2H3,(H,25,29)/t16-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 14.2n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136639
PNG
(US10047097, 56 | US8865698, 56 | US9676783, 56)
Show SMILES CC(C)(C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F)n1cncn1
Show InChI InChI=1S/C22H22F2N8O/c1-22(2,32-13-25-12-27-32)21(33)28-17-11-26-31-9-7-19(29-20(17)31)30-8-3-4-18(30)15-10-14(23)5-6-16(15)24/h5-7,9-13,18H,3-4,8H2,1-2H3,(H,28,33)/t18-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 14.4n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136670
PNG
(US10047097, 87 | US8865698, 87 | US9676783, 87)
Show SMILES O[C@H]1CCCN(C1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1C(F)(F)F
Show InChI InChI=1S/C23H24F4N6O2/c24-14-5-6-17(23(25,26)27)16(11-14)19-4-2-9-32(19)20-7-10-33-21(30-20)18(12-28-33)29-22(35)31-8-1-3-15(34)13-31/h5-7,10-12,15,19,34H,1-4,8-9,13H2,(H,29,35)/t15-,19+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 14.6n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136657
PNG
(US10047097, 74 | US8865698, 74 | US9676783, 74)
Show SMILES Fc1cccc(c1)[C@H]1CCCN1c1ccn2ncc(NC(=O)c3cc[nH]n3)c2n1
Show InChI InChI=1S/C20H18FN7O/c21-14-4-1-3-13(11-14)17-5-2-9-27(17)18-7-10-28-19(25-18)16(12-23-28)24-20(29)15-6-8-22-26-15/h1,3-4,6-8,10-12,17H,2,5,9H2,(H,22,26)(H,24,29)/t17-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 15.3n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136631
PNG
(US10047097, 48 | US8865698, 48 | US9676783, 48)
Show SMILES CC(C)(C)OC(=O)N1CCC(C)(CC1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1Cl
Show InChI InChI=1S/C28H34ClFN6O3/c1-27(2,3)39-26(38)34-14-10-28(4,11-15-34)25(37)32-21-17-31-36-13-9-23(33-24(21)36)35-12-5-6-22(35)19-16-18(30)7-8-20(19)29/h7-9,13,16-17,22H,5-6,10-12,14-15H2,1-4H3,(H,32,37)/t22-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 15.3n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136683
PNG
(US10047097, 100 | US8865698, 100 | US9676783, 100)
Show SMILES Fc1ccc(F)c(c1)[C@H]1CCCN1c1ccn2ncc(NC(=O)C(=O)NC3CC3)c2n1
Show InChI InChI=1S/C21H20F2N6O2/c22-12-3-6-15(23)14(10-12)17-2-1-8-28(17)18-7-9-29-19(27-18)16(11-24-29)26-21(31)20(30)25-13-4-5-13/h3,6-7,9-11,13,17H,1-2,4-5,8H2,(H,25,30)(H,26,31)/t17-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 15.8n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136585
PNG
(US10047097, 2 | US8865698, 2 | US9676783, 2)
Show SMILES CN(C)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F
Show InChI InChI=1S/C19H20F2N6O/c1-25(2)19(28)23-15-11-22-27-9-7-17(24-18(15)27)26-8-3-4-16(26)13-10-12(20)5-6-14(13)21/h5-7,9-11,16H,3-4,8H2,1-2H3,(H,23,28)/t16-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 15.8n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136648
PNG
(US10047097, 65 | US8865698, 65 | US9676783, 65)
Show SMILES OC1(CC1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F
Show InChI InChI=1S/C20H19F2N5O2/c21-12-3-4-14(22)13(10-12)16-2-1-8-26(16)17-5-9-27-18(25-17)15(11-23-27)24-19(28)20(29)6-7-20/h3-5,9-11,16,29H,1-2,6-8H2,(H,24,28)/t16-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 16.5n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136619
PNG
(US10047097, 36 | US8865698, 36 | US9676783, 36)
Show SMILES O[C@@H]1CCN(C1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1C(F)F
Show InChI InChI=1S/C22H23F3N6O2/c23-13-3-4-15(20(24)25)16(10-13)18-2-1-7-30(18)19-6-9-31-21(28-19)17(11-26-31)27-22(33)29-8-5-14(32)12-29/h3-4,6,9-11,14,18,20,32H,1-2,5,7-8,12H2,(H,27,33)/t14-,18-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 18n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM227973
PNG
(US10047097, 6)
Show SMILES C[N]1=[C](=O)C=CC(=N1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cccc(F)c1
Show InChI InChI=1S/C22H20FN7O2/c1-28-20(31)8-7-16(27-28)22(32)25-17-13-24-30-11-9-19(26-21(17)30)29-10-3-6-18(29)14-4-2-5-15(23)12-14/h2,4-5,7-9,11-13,18H,3,6,10H2,1H3,(H,25,32)/t18-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
US Patent
n/an/a 19.2n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136600
PNG
(US10047097, 17 | US8865698, 17 | US9676783, 17)
Show SMILES CC1(O)CN(C1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F
Show InChI InChI=1S/C21H22F2N6O2/c1-21(31)11-27(12-21)20(30)25-16-10-24-29-8-6-18(26-19(16)29)28-7-2-3-17(28)14-9-13(22)4-5-15(14)23/h4-6,8-10,17,31H,2-3,7,11-12H2,1H3,(H,25,30)/t17-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 19.7n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136618
PNG
(US10047097, 35 | US8865698, 35 | US9676783, 35)
Show SMILES O[C@H]1CCN(C1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)cc(Cl)c1
Show InChI InChI=1S/C21H22ClFN6O2/c22-14-8-13(9-15(23)10-14)18-2-1-5-28(18)19-4-7-29-20(26-19)17(11-24-29)25-21(31)27-6-3-16(30)12-27/h4,7-11,16,18,30H,1-3,5-6,12H2,(H,25,31)/t16-,18+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 20.2n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136677
PNG
(US10047097, 94 | US8865698, 94 | US9676783, 94)
Show SMILES O[C@@H]1CC[C@@H](C1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F
Show InChI InChI=1S/C22H23F2N5O2/c23-14-4-6-17(24)16(11-14)19-2-1-8-28(19)20-7-9-29-21(27-20)18(12-25-29)26-22(31)13-3-5-15(30)10-13/h4,6-7,9,11-13,15,19,30H,1-3,5,8,10H2,(H,26,31)/t13-,15+,19+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 20.3n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136584
PNG
(US10047097, 1 | US8865698, 1 | US9676783, 1)
Show SMILES OC1CN(C1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F
Show InChI InChI=1S/C20H20F2N6O2/c21-12-3-4-15(22)14(8-12)17-2-1-6-27(17)18-5-7-28-19(25-18)16(9-23-28)24-20(30)26-10-13(29)11-26/h3-5,7-9,13,17,29H,1-2,6,10-11H2,(H,24,30)/t17-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 20.7n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136586
PNG
(US10047097, 3 | US8865698, 3 | US9676783, 3)
Show SMILES CC(C)(C)NC(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F
Show InChI InChI=1S/C21H24F2N6O/c1-21(2,3)27-20(30)25-16-12-24-29-10-8-18(26-19(16)29)28-9-4-5-17(28)14-11-13(22)6-7-15(14)23/h6-8,10-12,17H,4-5,9H2,1-3H3,(H2,25,27,30)/t17-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 22.2n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136622
PNG
(US10047097, 39 | US8865698, 39 | US9676783, 39)
Show SMILES O[C@@H]1CCCN(C1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1C(F)F
Show InChI InChI=1S/C23H25F3N6O2/c24-14-5-6-16(21(25)26)17(11-14)19-4-2-9-31(19)20-7-10-32-22(29-20)18(12-27-32)28-23(34)30-8-1-3-15(33)13-30/h5-7,10-12,15,19,21,33H,1-4,8-9,13H2,(H,28,34)/t15-,19-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 25.7n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136595
PNG
(US10047097, 12 | US8865698, 12 | US9676783, 12)
Show SMILES OC1CN(C1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1C(F)F
Show InChI InChI=1S/C21H21F3N6O2/c22-12-3-4-14(19(23)24)15(8-12)17-2-1-6-29(17)18-5-7-30-20(27-18)16(9-25-30)26-21(32)28-10-13(31)11-28/h3-5,7-9,13,17,19,31H,1-2,6,10-11H2,(H,26,32)/t17-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 26.5n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136679
PNG
(US10047097, 96 | US8865698, 96 | US9676783, 96)
Show SMILES OC1CC(C1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F
Show InChI InChI=1S/C21H21F2N5O2/c22-13-3-4-16(23)15(10-13)18-2-1-6-27(18)19-5-7-28-20(26-19)17(11-24-28)25-21(30)12-8-14(29)9-12/h3-5,7,10-12,14,18,29H,1-2,6,8-9H2,(H,25,30)/t12?,14?,18-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 27.4n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136599
PNG
(US10047097, 16 | US8865698, 16 | US9676783, 16)
Show SMILES COC1CN(C1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F
Show InChI InChI=1S/C21H22F2N6O2/c1-31-14-11-27(12-14)21(30)25-17-10-24-29-8-6-19(26-20(17)29)28-7-2-3-18(28)15-9-13(22)4-5-16(15)23/h4-6,8-10,14,18H,2-3,7,11-12H2,1H3,(H,25,30)/t18-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 27.5n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136604
PNG
(US10047097, 21 | US8865698, 21 | US9676783, 21)
Show SMILES COC1CN(C1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1Cl
Show InChI InChI=1S/C21H22ClFN6O2/c1-31-14-11-27(12-14)21(30)25-17-10-24-29-8-6-19(26-20(17)29)28-7-2-3-18(28)15-9-13(23)4-5-16(15)22/h4-6,8-10,14,18H,2-3,7,11-12H2,1H3,(H,25,30)/t18-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 27.9n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136625
PNG
(US10047097, 42 | US8865698, 42 | US9676783, 42)
Show SMILES OC1CCN(CC1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1Cl
Show InChI InChI=1S/C22H24ClFN6O2/c23-17-4-3-14(24)12-16(17)19-2-1-8-29(19)20-7-11-30-21(27-20)18(13-25-30)26-22(32)28-9-5-15(31)6-10-28/h3-4,7,11-13,15,19,31H,1-2,5-6,8-10H2,(H,26,32)/t19-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 28.3n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136676
PNG
(US10047097, 93 | US8865698, 93 | US9676783, 93)
Show SMILES O[C@@H]1CCN(C1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F
Show InChI InChI=1S/C21H22F2N6O2/c22-13-3-4-16(23)15(10-13)18-2-1-7-28(18)19-6-9-29-20(26-19)17(11-24-29)25-21(31)27-8-5-14(30)12-27/h3-4,6,9-11,14,18,30H,1-2,5,7-8,12H2,(H,25,31)/t14-,18-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 28.5n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM228018
PNG
(US10047097, 49)
Show SMILES Cl.CC1(CCNCC1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1Cl
Show InChI InChI=1S/C23H26ClFN6O.ClH/c1-23(7-9-26-10-8-23)22(32)28-18-14-27-31-12-6-20(29-21(18)31)30-11-2-3-19(30)16-13-15(25)4-5-17(16)24;/h4-6,12-14,19,26H,2-3,7-11H2,1H3,(H,28,32);1H/t19-;/m1./s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
US Patent
n/an/a 29.2n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136623
PNG
(US10047097, 40 | US8865698, 40 | US9676783, 40)
Show SMILES O[C@H]1CCCN(C1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1C(F)F
Show InChI InChI=1S/C23H25F3N6O2/c24-14-5-6-16(21(25)26)17(11-14)19-4-2-9-31(19)20-7-10-32-22(29-20)18(12-27-32)28-23(34)30-8-1-3-15(33)13-30/h5-7,10-12,15,19,21,33H,1-4,8-9,13H2,(H,28,34)/t15-,19+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 30.8n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136636
PNG
(US10047097, 53 | US8865698, 53 | US9676783, 53)
Show SMILES C[C@@]1(CCCN1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F
Show InChI InChI=1S/C22H24F2N6O/c1-22(8-3-9-25-22)21(31)27-17-13-26-30-11-7-19(28-20(17)30)29-10-2-4-18(29)15-12-14(23)5-6-16(15)24/h5-7,11-13,18,25H,2-4,8-10H2,1H3,(H,27,31)/t18-,22-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 31n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136596
PNG
(US10047097, 13 | US8865698, 13 | US9676783, 13)
Show SMILES Fc1ccc(F)c(c1)[C@H]1CCCN1c1ccn2ncc(NC(=O)N3CCOCC3)c2n1
Show InChI InChI=1S/C21H22F2N6O2/c22-14-3-4-16(23)15(12-14)18-2-1-6-28(18)19-5-7-29-20(26-19)17(13-24-29)25-21(30)27-8-10-31-11-9-27/h3-5,7,12-13,18H,1-2,6,8-11H2,(H,25,30)/t18-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 32.2n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136666
PNG
(US10047097, 83 | US8865698, 83 | US9676783, 83)
Show SMILES Cn1ccnc1C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cccc(F)c1
Show InChI InChI=1S/C21H20FN7O/c1-27-11-8-23-20(27)21(30)25-16-13-24-29-10-7-18(26-19(16)29)28-9-3-6-17(28)14-4-2-5-15(22)12-14/h2,4-5,7-8,10-13,17H,3,6,9H2,1H3,(H,25,30)/t17-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 35.4n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136629
PNG
(US10047097, 46 | US8865698, 46 | US9676783, 46)
Show SMILES CC(C)(C)OC(=O)N1CC(C1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1Cl
Show InChI InChI=1S/C25H28ClFN6O3/c1-25(2,3)36-24(35)31-13-15(14-31)23(34)29-19-12-28-33-10-8-21(30-22(19)33)32-9-4-5-20(32)17-11-16(27)6-7-18(17)26/h6-8,10-12,15,20H,4-5,9,13-14H2,1-3H3,(H,29,34)/t20-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 37.3n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136606
PNG
(US10047097, 23 | US8865698, 23 | US9676783, 23)
Show SMILES Fc1ccc(Cl)c(c1)[C@H]1CCCN1c1ccn2ncc(NC(=O)N3CCOCC3)c2n1
Show InChI InChI=1S/C21H22ClFN6O2/c22-16-4-3-14(23)12-15(16)18-2-1-6-28(18)19-5-7-29-20(26-19)17(13-24-29)25-21(30)27-8-10-31-11-9-27/h3-5,7,12-13,18H,1-2,6,8-11H2,(H,25,30)/t18-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 41.7n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136678
PNG
(US10047097, 95 | US8865698, 95 | US9676783, 95)
Show SMILES O[C@H]1CC[C@@H](C1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F
Show InChI InChI=1S/C22H23F2N5O2/c23-14-4-6-17(24)16(11-14)19-2-1-8-28(19)20-7-9-29-21(27-20)18(12-25-29)26-22(31)13-3-5-15(30)10-13/h4,6-7,9,11-13,15,19,30H,1-3,5,8,10H2,(H,26,31)/t13-,15-,19+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 42.5n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136609
PNG
(US10047097, 26 | US8865698, 26 | US9676783, 26)
Show SMILES CC(C)N1CCN(CC1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F
Show InChI InChI=1S/C24H29F2N7O/c1-16(2)30-10-12-31(13-11-30)24(34)28-20-15-27-33-9-7-22(29-23(20)33)32-8-3-4-21(32)18-14-17(25)5-6-19(18)26/h5-7,9,14-16,21H,3-4,8,10-13H2,1-2H3,(H,28,34)/t21-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 45n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136655
PNG
(US10047097, 72 | US8865698, 72 | US9676783, 72)
Show SMILES CCS(=O)(=O)Nc1ccc(cc1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cccc(F)c1
Show InChI InChI=1S/C25H25FN6O3S/c1-2-36(34,35)30-20-10-8-17(9-11-20)25(33)28-21-16-27-32-14-12-23(29-24(21)32)31-13-4-7-22(31)18-5-3-6-19(26)15-18/h3,5-6,8-12,14-16,22,30H,2,4,7,13H2,1H3,(H,28,33)/t22-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 45.5n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136661
PNG
(US10047097, 78 | US8865698, 78 | US9676783, 78)
Show SMILES Cc1ccc(cn1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cccc(F)c1
Show InChI InChI=1S/C23H21FN6O/c1-15-7-8-17(13-25-15)23(31)27-19-14-26-30-11-9-21(28-22(19)30)29-10-3-6-20(29)16-4-2-5-18(24)12-16/h2,4-5,7-9,11-14,20H,3,6,10H2,1H3,(H,27,31)/t20-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 47n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136680
PNG
(US10047097, 97 | US8865698, 97 | US9676783, 97)
Show SMILES CN(C)C(=O)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F
Show InChI InChI=1S/C20H20F2N6O2/c1-26(2)20(30)19(29)24-15-11-23-28-9-7-17(25-18(15)28)27-8-3-4-16(27)13-10-12(21)5-6-14(13)22/h5-7,9-11,16H,3-4,8H2,1-2H3,(H,24,29)/t16-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 47.5n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136649
PNG
(US10047097, 66 | US8865698, 66 | US9676783, 66)
Show SMILES CNC(C)(C)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F
Show InChI InChI=1S/C21H24F2N6O/c1-21(2,24-3)20(30)26-16-12-25-29-10-8-18(27-19(16)29)28-9-4-5-17(28)14-11-13(22)6-7-15(14)23/h6-8,10-12,17,24H,4-5,9H2,1-3H3,(H,26,30)/t17-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 52.5n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136659
PNG
(US10047097, 76 | US8865698, 76 | US9676783, 76)
Show SMILES Fc1cccc(c1)[C@H]1CCCN1c1ccn2ncc(NC(=O)c3cccnc3)c2n1
Show InChI InChI=1S/C22H19FN6O/c23-17-6-1-4-15(12-17)19-7-3-10-28(19)20-8-11-29-21(27-20)18(14-25-29)26-22(30)16-5-2-9-24-13-16/h1-2,4-6,8-9,11-14,19H,3,7,10H2,(H,26,30)/t19-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 53.3n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136607
PNG
(US10047097, 24 | US8865698, 24 | US9676783, 24)
Show SMILES C[C@H]1CN(CCN1C(=O)OC(C)(C)C)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1Cl
Show InChI InChI=1S/C27H33ClFN7O3/c1-17-16-33(12-13-34(17)26(38)39-27(2,3)4)25(37)31-21-15-30-36-11-9-23(32-24(21)36)35-10-5-6-22(35)19-14-18(29)7-8-20(19)28/h7-9,11,14-15,17,22H,5-6,10,12-13,16H2,1-4H3,(H,31,37)/t17-,22+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 55n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136653
PNG
(US10047097, 70 | US8865698, 70 | US9676783, 70)
Show SMILES Cn1ccc(cc1=O)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cccc(F)c1
Show InChI InChI=1S/C23H21FN6O2/c1-28-10-7-16(13-21(28)31)23(32)26-18-14-25-30-11-8-20(27-22(18)30)29-9-3-6-19(29)15-4-2-5-17(24)12-15/h2,4-5,7-8,10-14,19H,3,6,9H2,1H3,(H,26,32)/t19-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 55.6n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136611
PNG
(US10047097, 28 | US8865698, 28 | US9676783, 28)
Show SMILES CN1CCN(CC1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F
Show InChI InChI=1S/C22H25F2N7O/c1-28-9-11-29(12-10-28)22(32)26-18-14-25-31-8-6-20(27-21(18)31)30-7-2-3-19(30)16-13-15(23)4-5-17(16)24/h4-6,8,13-14,19H,2-3,7,9-12H2,1H3,(H,26,32)/t19-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 57.4n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136660
PNG
(US10047097, 77 | US8865698, 77 | US9676783, 77)
Show SMILES Fc1cccc(c1)[C@H]1CCCN1c1ccn2ncc(NC(=O)c3ccncc3)c2n1
Show InChI InChI=1S/C22H19FN6O/c23-17-4-1-3-16(13-17)19-5-2-11-28(19)20-8-12-29-21(27-20)18(14-25-29)26-22(30)15-6-9-24-10-7-15/h1,3-4,6-10,12-14,19H,2,5,11H2,(H,26,30)/t19-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 71.8n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136590
PNG
(US10047097, 7 | US8865698, 7 | US9676783, 7)
Show SMILES OC1CN(C1)C(=O)Nc1cnn2ccc(nc12)N1CC(F)(F)C[C@@H]1c1cccc(F)c1
Show InChI InChI=1S/C20H19F3N6O2/c21-13-3-1-2-12(6-13)16-7-20(22,23)11-28(16)17-4-5-29-18(26-17)15(8-24-29)25-19(31)27-9-14(30)10-27/h1-6,8,14,16,30H,7,9-11H2,(H,25,31)/t16-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 77.5n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM227992
PNG
(US10047097, 25)
Show SMILES Cl.C[C@H]1CN(CCN1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1Cl
Show InChI InChI=1S/C22H25ClFN7O.ClH/c1-14-13-29(10-7-25-14)22(32)27-18-12-26-31-9-6-20(28-21(18)31)30-8-2-3-19(30)16-11-15(24)4-5-17(16)23;/h4-6,9,11-12,14,19,25H,2-3,7-8,10,13H2,1H3,(H,27,32);1H/t14-,19+;/m0./s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
US Patent
n/an/a 82.3n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136686
PNG
(US10047097, 103 | US8865698, 103 | US9676783, 103)
Show SMILES Fc1ccc(F)c(c1)[C@H]1CCCN1c1ccn2ncc(NC(=O)C(=O)N3CCOCC3)c2n1
Show InChI InChI=1S/C22H22F2N6O3/c23-14-3-4-16(24)15(12-14)18-2-1-6-29(18)19-5-7-30-20(27-19)17(13-25-30)26-21(31)22(32)28-8-10-33-11-9-28/h3-5,7,12-13,18H,1-2,6,8-11H2,(H,26,31)/t18-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 82.4n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136621
PNG
(US10047097, 38 | US8865698, 38 | US9676783, 38)
Show SMILES OC1CCN(CC1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1C(F)F
Show InChI InChI=1S/C23H25F3N6O2/c24-14-3-4-16(21(25)26)17(12-14)19-2-1-8-31(19)20-7-11-32-22(29-20)18(13-27-32)28-23(34)30-9-5-15(33)6-10-30/h3-4,7,11-13,15,19,21,33H,1-2,5-6,8-10H2,(H,28,34)/t19-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 85.5n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM227998
PNG
(US10047097, 31)
Show SMILES Cl.C[C@H]1CN(CCN1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F
Show InChI InChI=1S/C22H25F2N7O.ClH/c1-14-13-29(10-7-25-14)22(32)27-18-12-26-31-9-6-20(28-21(18)31)30-8-2-3-19(30)16-11-15(23)4-5-17(16)24;/h4-6,9,11-12,14,19,25H,2-3,7-8,10,13H2,1H3,(H,27,32);1H/t14-,19+;/m0./s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
US Patent
n/an/a 88.3n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136612
PNG
(US10047097, 29 | US8865698, 29 | US9676783, 29)
Show SMILES CC1CN(CC(C)N1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F
Show InChI InChI=1S/C23H27F2N7O/c1-14-12-30(13-15(2)27-14)23(33)28-19-11-26-32-9-7-21(29-22(19)32)31-8-3-4-20(31)17-10-16(24)5-6-18(17)25/h5-7,9-11,14-15,20,27H,3-4,8,12-13H2,1-2H3,(H,28,33)/t14?,15?,20-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 98n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136617
PNG
(US10047097, 34 | US8865698, 34 | US9676783, 34)
Show SMILES OC(=O)C1(CC1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F
Show InChI InChI=1S/C21H19F2N5O3/c22-12-3-4-14(23)13(10-12)16-2-1-8-27(16)17-5-9-28-18(26-17)15(11-24-28)25-19(29)21(6-7-21)20(30)31/h3-5,9-11,16H,1-2,6-8H2,(H,25,29)(H,30,31)/t16-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 98.2n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136675
PNG
(US10047097, 92 | US8865698, 92 | US9676783, 92)
Show SMILES Fc1ccc(F)c(c1)[C@H]1CCCN1c1ccn2ncc(NC(=O)N3C[C@@H]4C[C@H]3CO4)c2n1
Show InChI InChI=1S/C22H22F2N6O2/c23-13-3-4-17(24)16(8-13)19-2-1-6-28(19)20-5-7-30-21(27-20)18(10-25-30)26-22(31)29-11-15-9-14(29)12-32-15/h3-5,7-8,10,14-15,19H,1-2,6,9,11-12H2,(H,26,31)/t14-,15-,19+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 107n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136610
PNG
(US10047097, 27 | US8865698, 27 | US9676783, 27)
Show SMILES CCN1CCN(CC1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F
Show InChI InChI=1S/C23H27F2N7O/c1-2-29-10-12-30(13-11-29)23(33)27-19-15-26-32-9-7-21(28-22(19)32)31-8-3-4-20(31)17-14-16(24)5-6-18(17)25/h5-7,9,14-15,20H,2-4,8,10-13H2,1H3,(H,27,33)/t20-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 107n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136615
PNG
(US10047097, 32 | US8865698, 32 | US9676783, 32)
Show SMILES OC1CN(C1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cccc(F)c1
Show InChI InChI=1S/C20H21FN6O2/c21-14-4-1-3-13(9-14)17-5-2-7-26(17)18-6-8-27-19(24-18)16(10-22-27)23-20(29)25-11-15(28)12-25/h1,3-4,6,8-10,15,17,28H,2,5,7,11-12H2,(H,23,29)/t17-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 116n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136613
PNG
(US10047097, 30 | US8865698, 30 | US9676783, 30)
Show SMILES C[C@H]1CN(CCN1C(=O)OC(C)(C)C)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F
Show InChI InChI=1S/C27H33F2N7O3/c1-17-16-33(12-13-34(17)26(38)39-27(2,3)4)25(37)31-21-15-30-36-11-9-23(32-24(21)36)35-10-5-6-22(35)19-14-18(28)7-8-20(19)29/h7-9,11,14-15,17,22H,5-6,10,12-13,16H2,1-4H3,(H,31,37)/t17-,22+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 154n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136671
PNG
(US10047097, 88 | US8865698, 88 | US9676783, 88)
Show SMILES O[C@H]1CCN(C1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cncc(F)c1
Show InChI InChI=1S/C20H22FN7O2/c21-14-8-13(9-22-10-14)17-2-1-5-27(17)18-4-7-28-19(25-18)16(11-23-28)24-20(30)26-6-3-15(29)12-26/h4,7-11,15,17,29H,1-3,5-6,12H2,(H,24,30)/t15-,17+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 156n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136594
PNG
(US10047097, 11 | US8865698, 11 | US9676783, 11)
Show SMILES OC1CN(C1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)cc(Cl)c1
Show InChI InChI=1S/C20H20ClFN6O2/c21-13-6-12(7-14(22)8-13)17-2-1-4-27(17)18-3-5-28-19(25-18)16(9-23-28)24-20(30)26-10-15(29)11-26/h3,5-9,15,17,29H,1-2,4,10-11H2,(H,24,30)/t17-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 171n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136593
PNG
(US10047097, 10 | US8865698, 10 | US9676783, 10)
Show SMILES CC1(CCCN1c1ccn2ncc(NC(=O)N3CC(O)C3)c2n1)c1cccc(F)c1
Show InChI InChI=1S/C21H23FN6O2/c1-21(14-4-2-5-15(22)10-14)7-3-8-27(21)18-6-9-28-19(25-18)17(11-23-28)24-20(30)26-12-16(29)13-26/h2,4-6,9-11,16,29H,3,7-8,12-13H2,1H3,(H,24,30)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 188n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM228016
PNG
(US10047097, 47)
Show SMILES OC(=O)C(F)(F)F.Fc1ccc(Cl)c(c1)[C@H]1CCCN1c1ccn2ncc(NC(=O)C3CNC3)c2n1
Show InChI InChI=1S/C20H20ClFN6O.C2HF3O2/c21-15-4-3-13(22)8-14(15)17-2-1-6-27(17)18-5-7-28-19(26-18)16(11-24-28)25-20(29)12-9-23-10-12;3-2(4,5)1(6)7/h3-5,7-8,11-12,17,23H,1-2,6,9-10H2,(H,25,29);(H,6,7)/t17-;/m1./s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
US Patent
n/an/a 190n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136663
PNG
(US10047097, 80 | US8865698, 80 | US9676783, 80)
Show SMILES Cc1cnccc1C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cccc(F)c1
Show InChI InChI=1S/C23H21FN6O/c1-15-13-25-9-7-18(15)23(31)27-19-14-26-30-11-8-21(28-22(19)30)29-10-3-6-20(29)16-4-2-5-17(24)12-16/h2,4-5,7-9,11-14,20H,3,6,10H2,1H3,(H,27,31)/t20-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 320n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136592
PNG
(US10047097, 9 | US8865698, 9 | US9676783, 9)
Show SMILES Fc1cccc(c1)[C@H]1CCCN1c1ccn2ncc(NC(=O)N3CCOCC3)c2n1
Show InChI InChI=1S/C21H23FN6O2/c22-16-4-1-3-15(13-16)18-5-2-7-27(18)19-6-8-28-20(25-19)17(14-23-28)24-21(29)26-9-11-30-12-10-26/h1,3-4,6,8,13-14,18H,2,5,7,9-12H2,(H,24,29)/t18-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 821n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM136672
PNG
(US10047097, 89 | US8865698, 89 | US9676783, 89)
Show SMILES O[C@@H]1CCN(C1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cncc(F)c1
Show InChI InChI=1S/C20H22FN7O2/c21-14-8-13(9-22-10-14)17-2-1-5-27(17)18-4-7-28-19(25-18)16(11-23-28)24-20(30)26-6-3-15(29)12-26/h4,7-11,15,17,29H,1-3,5-6,12H2,(H,24,30)/t15-,17-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
US Patent
n/an/a 896n/an/an/an/an/an/a



Array BioPharma Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US10047097 (2018)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%