Compile Data Set for Download or QSAR
maximum 50k data
Found 43 Enz. Inhib. hit(s) with all data for entry = 454
TargetEpidermal growth factor receptor [L858R](Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM149404(AVL-301 | CHEMBL3545308 | CNX-419 | CO-1686 | Roci...)
Affinity DataIC50:  0.460nMAssay Description:TBDMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM149404(AVL-301 | CHEMBL3545308 | CNX-419 | CO-1686 | Roci...)
Affinity DataIC50: <0.510nMAssay Description:TBDMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM50391089(BPI-2009 | CHEMBL2087361 | Conmana | Icotinib | Lc...)
Affinity DataIC50:  1.23nMAssay Description:TBDMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor [L858R](Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM50391089(BPI-2009 | CHEMBL2087361 | Conmana | Icotinib | Lc...)
Affinity DataIC50:  2.02nMAssay Description:TBDMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor [T790M](Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270538(US10059688, Example 4 | US9783524, Example 4)
Affinity DataIC50:  4.08nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270544(2-(2-(5-chloro-2-(4-(4- (dimethylamino)piperidin- ...)
Affinity DataIC50:  4.92nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [T790M](Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270544(2-(2-(5-chloro-2-(4-(4- (dimethylamino)piperidin- ...)
Affinity DataIC50:  5.13nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270538(US10059688, Example 4 | US9783524, Example 4)
Affinity DataIC50:  7.52nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270543(US10059688, Example 115 | US9783524, Example 115)
Affinity DataIC50:  8.62nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270541(US10059688, Example 74)
Affinity DataIC50:  9.33nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270544(2-(2-(5-chloro-2-(4-(4- (dimethylamino)piperidin- ...)
Affinity DataIC50:  11nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270539(2-(2-(5-chloro-2-(3-methoxy- 4-(4-methylpiperazin-...)
Affinity DataIC50:  12nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [T790M](Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270543(US10059688, Example 115 | US9783524, Example 115)
Affinity DataIC50:  12nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270542(2-(2-(2-(4-acryloyl-3,4- dihydro-2H-benzo[b][1,4] ...)
Affinity DataIC50:  15nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [T790M](Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270542(2-(2-(2-(4-acryloyl-3,4- dihydro-2H-benzo[b][1,4] ...)
Affinity DataIC50:  15nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [T790M](Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270540(N-(3-(5-chloro-4-(2-(2- (dimethylamino)-2-oxoacety...)
Affinity DataIC50:  15nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [T790M](Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270541(US10059688, Example 74)
Affinity DataIC50:  16nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270541(US10059688, Example 74)
Affinity DataIC50:  16nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270540(N-(3-(5-chloro-4-(2-(2- (dimethylamino)-2-oxoacety...)
Affinity DataIC50:  17nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270540(N-(3-(5-chloro-4-(2-(2- (dimethylamino)-2-oxoacety...)
Affinity DataIC50:  19nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270543(US10059688, Example 115 | US9783524, Example 115)
Affinity DataIC50:  19nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270542(2-(2-(2-(4-acryloyl-3,4- dihydro-2H-benzo[b][1,4] ...)
Affinity DataIC50:  21nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [T790M](Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270539(2-(2-(5-chloro-2-(3-methoxy- 4-(4-methylpiperazin-...)
Affinity DataIC50:  23nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270538(US10059688, Example 4 | US9783524, Example 4)
Affinity DataIC50:  28nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270539(2-(2-(5-chloro-2-(3-methoxy- 4-(4-methylpiperazin-...)
Affinity DataIC50:  38nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [L858R](Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270538(US10059688, Example 4 | US9783524, Example 4)
Affinity DataIC50:  44nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270538(US10059688, Example 4 | US9783524, Example 4)
Affinity DataIC50:  45nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270544(2-(2-(5-chloro-2-(4-(4- (dimethylamino)piperidin- ...)
Affinity DataIC50:  78nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [L858R](Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270544(2-(2-(5-chloro-2-(4-(4- (dimethylamino)piperidin- ...)
Affinity DataIC50:  158nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM149404(AVL-301 | CHEMBL3545308 | CNX-419 | CO-1686 | Roci...)
Affinity DataIC50:  179nMAssay Description:TBDMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [L858R](Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270542(2-(2-(2-(4-acryloyl-3,4- dihydro-2H-benzo[b][1,4] ...)
Affinity DataIC50:  225nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270540(N-(3-(5-chloro-4-(2-(2- (dimethylamino)-2-oxoacety...)
Affinity DataIC50:  273nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270542(2-(2-(2-(4-acryloyl-3,4- dihydro-2H-benzo[b][1,4] ...)
Affinity DataIC50:  354nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270543(US10059688, Example 115 | US9783524, Example 115)
Affinity DataIC50:  397nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [T790M](Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM149404(AVL-301 | CHEMBL3545308 | CNX-419 | CO-1686 | Roci...)
Affinity DataIC50:  412nMAssay Description:TBDMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [L858R](Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270541(US10059688, Example 74)
Affinity DataIC50:  422nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [L858R](Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270540(N-(3-(5-chloro-4-(2-(2- (dimethylamino)-2-oxoacety...)
Affinity DataIC50:  500nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270541(US10059688, Example 74)
Affinity DataIC50:  513nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [L858R](Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270543(US10059688, Example 115 | US9783524, Example 115)
Affinity DataIC50:  547nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270539(2-(2-(5-chloro-2-(3-methoxy- 4-(4-methylpiperazin-...)
Affinity DataIC50:  756nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [T790M](Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM50391089(BPI-2009 | CHEMBL2087361 | Conmana | Icotinib | Lc...)
Affinity DataIC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor [L858R](Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270539(2-(2-(5-chloro-2-(3-methoxy- 4-(4-methylpiperazin-...)
Affinity DataIC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM50391089(BPI-2009 | CHEMBL2087361 | Conmana | Icotinib | Lc...)
Affinity DataIC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In DepthDetails US Patent