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Patent code US10071079

Compile Data Set for Download or QSAR

Found 2922 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Toll-like receptor 7


(Homo sapiens (Human))
BDBM273647
PNG
(US10071079, Example 432)
Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC1)C(CCO)CCO)-c1cc(C)c2ncnn2c1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.100n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM273981
PNG
(US10071079, Example 767)
Show SMILES CC(C)N(C)CC(=O)N1CCC(CC1)c1ccc2[nH]c(c(C(C)C)c2c1)-c1cn2ncnc2c(C)c1C
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.200n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM273911
PNG
(US10071079, Example 697)
Show SMILES CNCC(=O)N1CCC(CC1)c1ccc2[nH]c(c(C(C)C)c2c1)-c1cc(C2CC2)c2ncnn2c1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.200n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM273856
PNG
(US10071079, Example 642)
Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC1)C(=O)CN(C)C)-c1cc(c2ncnn2c1)C(F)(F)F
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.200n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM273929
PNG
(US10071079, Example 715)
Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC1)C(=O)CN(CCO)C1CC1)-c1cc(C)c2ncnn2c1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.200n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM273536
PNG
(US10071079, Example 319)
Show SMILES CNC(=O)CN1CCC(CC1)c1ccc2[nH]c(c(C(C)C)c2c1)-c1cc(C2CC2)c2ncnn2c1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.200n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM273470
PNG
(US10071079, Example 253 | US10071079, Example 263)
Show SMILES COc1cc(cn2ncnc12)-c1[nH]c2ccc(cc2c1C(C)C)C1CCN(CCS(C)(=O)=O)CC1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.200n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM273316
PNG
(US10071079, Example 90)
Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC(=O)N2CCCC2)CC1)-c1cc(C)c2ncnn2c1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.200n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM273340
PNG
(US10071079, Example 119)
Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCNCC1)-c1cn2ncnc2c(Cl)c1C
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.200n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM274105
PNG
(US10071079, Example 891)
Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC1)C(=O)CCNCC(N)=O)-c1cn2ncnc2c(C)c1C
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.200n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM274079
PNG
(US10071079, Example 865)
Show SMILES COc1cc(cn2ncnc12)-c1[nH]c2ccc(cc2c1C(C)C)C1CCN(CC(=O)N2CC(F)(F)C2)CC1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.200n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM273463
PNG
(US10071079, Example 246)
Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC(C)(C)O)CC1)-c1cc(C)c2nc(C)nn2c1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.200n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM273606
PNG
(US10071079, Example 391)
Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CCCO)CC1)-c1cc(C)c2ncnn2c1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.200n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM273910
PNG
(US10071079, Example 696)
Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC1)C(=O)CN(C)C)-c1cc(C2CC2)c2ncnn2c1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.200n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM273234
PNG
(US10071079, Example 8)
Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(C[N+]#[C-])CC1)-c1cc(C)c2ncnn2c1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.300n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM273320
PNG
(8-ethyl-6-(3-isopropyl-5-(piperidin-4-yl)-1H-indol...)
Show SMILES CCc1cc(cn2ncnc12)-c1[nH]c2ccc(cc2c1C(C)C)C1CCNCC1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.300n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM273255
PNG
(US10071079, Example 29)
Show SMILES CC(C)CN1CCC(CC1)c1ccc2[nH]c(c(C(C)C)c2c1)-c1cc(C)c2ncnn2c1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.300n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM273608
PNG
(US10071079, Example 393 | US10071079, Example 540 ...)
Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC1)C1CCOC1)-c1cc(C)c2ncnn2c1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.300n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM273855
PNG
(US10071079, Example 641)
Show SMILES CNCC(=O)N1CCC(CC1)c1ccc2[nH]c(c(C(C)C)c2c1)-c1cc(c2ncnn2c1)C(F)(F)F
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.300n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM273368
PNG
(US10071079, Example 151)
Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCNCC1)-c1cc(C2CC2)c2ncnn2c1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.300n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM273769
PNG
(US10071079, Example 555)
Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC2(C)COC2)CC1)-c1cc(c2ncnn2c1)C(F)(F)F
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.300n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM273780
PNG
(US10071079, Example 566)
Show SMILES COc1cc(cn2ncnc12)-c1[nH]c2ccc(cc2c1C(C)C)C1CCN(CC2(C)COC2)CC1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.300n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM273356
PNG
(US10071079, Example 138)
Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCNCC1)-c1cn2nc(C)nc2c(Cl)c1C
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.300n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM273230
PNG
(6-(3-isopropyl-5-(piperidin-4-yl)-1H-indol-2-yl)-7...)
Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCNCC1)-c1cn2ncnc2c(C)c1C
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.300n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM273237
PNG
(US10071079, Example 11)
Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC(N)=O)CC1)-c1cc(C)c2ncnn2c1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.300n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM273271
PNG
(US10071079, Example 45)
Show SMILES COc1cc(cn2ncnc12)-c1[nH]c2ccc(cc2c1C(C)C)C1CCN(CC1)C1CCOCC1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.300n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM273992
PNG
(US10071079, Example 778)
Show SMILES CCN(C)CC(=O)N1CCC(CC1)c1ccc2[nH]c(c(C(C)C)c2c1)-c1cc(c2ncnn2c1)C(F)(F)F
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.300n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM274076
PNG
(US10071079, Example 862)
Show SMILES COc1cc(cn2ncnc12)-c1[nH]c2ccc(cc2c1C(C)C)C1CCN(CC(=O)NCC2(C)COC2)CC1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.300n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM273537
PNG
(US10071079, Example 320)
Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC(=O)N(C)C)CC1)-c1cc(C2CC2)c2ncnn2c1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.300n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM273251
PNG
(2-(4-(3-isopropyl-2-(8-methoxy-[1,2,4]triazolo[1,5...)
Show SMILES COc1cc(cn2ncnc12)-c1[nH]c2ccc(cc2c1C(C)C)C1CCN(CC(=O)N(C)C)CC1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.300n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM273349
PNG
(US10071079, Example 128)
Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCNCC1)-c1cc(c2ncnn2c1)C(F)(F)F
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.400n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM273886
PNG
(US10071079, Example 672 | US10071079, Example 676 ...)
Show SMILES COc1cc(cn2ncnc12)-c1[nH]c2ccc(cc2c1C(C)C)C1CCN(CC1)C(=O)C1CCN(C)C1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.400n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM274077
PNG
(US10071079, Example 863)
Show SMILES COc1cc(cn2ncnc12)-c1[nH]c2ccc(cc2c1C(C)C)C1CCN(CC(=O)N2CC[C@@H](O)C2)CC1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.400n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM274078
PNG
(US10071079, Example 864)
Show SMILES COc1cc(cn2ncnc12)-c1[nH]c2ccc(cc2c1C(C)C)C1CCN(CC(=O)N2CC(F)C2)CC1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.400n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM274149
PNG
(US10071079, Example 935)
Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC1)C(=O)OC1CCNCC1)-c1cn2ncnc2c(C)c1C
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.400n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM273770
PNG
(US10071079, Example 556 | US10071079, Example 557)
Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC1)C1CCOC1)-c1cc(c2ncnn2c1)C(F)(F)F
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.400n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM273994
PNG
(US10071079, Example 780)
Show SMILES COCCNCC(=O)N1CCC(CC1)c1ccc2[nH]c(c(C(C)C)c2c1)-c1cc(OC)c2ncnn2c1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.400n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM273477
PNG
(US10071079, Example 260)
Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC(=O)N(C)C)CC1)-c1cc(Cl)c2nc(C)nn2c1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.400n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM274089
PNG
(US10071079, Example 875)
Show SMILES COc1cc(cn2ncnc12)-c1[nH]c2ccc(cc2c1C(C)C)C1CCN(CC(=O)N2CC[C@H](F)C2)CC1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.400n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM273250
PNG
(US10071079, Example 24)
Show SMILES COc1cc(cn2ncnc12)-c1[nH]c2ccc(cc2c1C(C)C)C1CCN(CC(C)(C)O)CC1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.400n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM273298
PNG
(US10071079, Example 72)
Show SMILES CCCNCC(=O)N1CCC(CC1)c1ccc2[nH]c(c(C(C)C)c2c1)-c1cc(C)c2ncnn2c1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.400n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM273385
PNG
(US10071079, Example 168)
Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CCS(N)(=O)=O)CC1)-c1cc(C)c2ncnn2c1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.400n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM273691
PNG
(US10071079, Example 476)
Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC1)C(C#N)C1(C)COC1)-c1cn2ncnc2c(C)c1C
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.400n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM273781
PNG
(US10071079, Example 567)
Show SMILES COc1cc(cn2ncnc12)-c1[nH]c2ccc(cc2c1C(C)C)C1CCN(CC1)C1CC(C1)[N+]#[C-]
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.400n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM273841
PNG
(US10071079, Example 627)
Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC1)C(=O)[C@@H]1C[C@@H](F)CN1)-c1cc(C)c2ncnn2c1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.400n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM273779
PNG
(US10071079, Example 565)
Show SMILES COc1cc(cn2ncnc12)-c1[nH]c2ccc(cc2c1C(C)C)C1CCN(C[C@@H]2COCCN2)CC1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.400n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM273784
PNG
(US10071079, Example 570)
Show SMILES CNCCN1CCC(CC1)c1ccc2[nH]c(c(C(C)C)c2c1)-c1cc(OC)c2ncnn2c1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.400n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM273990
PNG
(US10071079, Example 776)
Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC1)C(=O)CN1CC[C@@H](O)C1)-c1cc(C)c2ncnn2c1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.400n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM273389
PNG
(US10071079, Example 172)
Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC2(CC2)[N+]#N)CC1)-c1cc(C)c2ncnn2c1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.400n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM274068
PNG
(US10071079, Example 854)
Show SMILES COc1cc(cn2ncnc12)-c1[nH]c2ccc(cc2c1C(C)C)C1CCN(CC(=O)NC2(C)COC2)CC1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 0.400n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...


US Patent US10071079 (2018)

More data for this
Ligand-Target Pair
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