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Found 33 Enz. Inhib. hit(s) with all data for entry = 519
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
The Regents Of The University Of California

US Patent
LigandPNGBDBM275767(US10071110, Compound CDV | US10071110, Compound Ci...)
Affinity DataEC50:  450nMAssay Description:Antiviral assays for HCMV DNA were carried out by DNA hybridization as reported by Dankner, W. M., Scholl, D., Stanat, S. C., Martin, M., Souke, R. L...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHIV-1 protease(Human immunodeficiency virus)
The Regents Of The University Of California

US Patent
LigandPNGBDBM275786(US10071110, Compound 1-O-octadecylpropanediol-2-cC...)
Affinity DataEC50:  8nMAssay Description:Subconfluent MRC-5 cells in 24-well culture dishes were inoculated by removing the medium and adding HSV-1 virus at a dilution that will result in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
The Regents Of The University Of California

US Patent
LigandPNGBDBM275769(Hexadecyloxypropyl-cyclic cidofovir | US10071110, ...)
Affinity DataEC50:  0.5nMAssay Description:Antiviral assays for HCMV DNA were carried out by DNA hybridization as reported by Dankner, W. M., Scholl, D., Stanat, S. C., Martin, M., Souke, R. L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
The Regents Of The University Of California

US Patent
LigandPNGBDBM50001103((2-(6-amino-9H-purin-9-yl)ethoxy)methylphosphonic ...)
Affinity DataEC50:  5.50E+4nMAssay Description:Antiviral assays for HCMV DNA were carried out by DNA hybridization as reported by Dankner, W. M., Scholl, D., Stanat, S. C., Martin, M., Souke, R. L...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The Regents Of The University Of California

US Patent
LigandPNGBDBM275767(US10071110, Compound CDV | US10071110, Compound Ci...)
Affinity DataEC50:  460nMAssay Description:Subconfluent human lung fibroblast cells (MRC-5, American Type Culture Collection, Rockville, Md.) in 24-well plates were treated with drugs diluted ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The Regents Of The University Of California

US Patent
LigandPNGBDBM275768(CYCLIC CIDOFOVIR | Cyclic-hpmpc | US10071110, Comp...)
Affinity DataEC50:  470nMAssay Description:Subconfluent human lung fibroblast cells (MRC-5, American Type Culture Collection, Rockville, Md.) in 24-well plates were treated with drugs diluted ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The Regents Of The University Of California

US Patent
LigandPNGBDBM275773(US10071110, Compound 1-O-hexadecylpropanediol-3-CD...)
Affinity DataEC50:  2.00E+3nMAssay Description:Subconfluent human lung fibroblast cells (MRC-5, American Type Culture Collection, Rockville, Md.) in 24-well plates were treated with drugs diluted ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The Regents Of The University Of California

US Patent
LigandPNGBDBM275769(Hexadecyloxypropyl-cyclic cidofovir | US10071110, ...)
Affinity DataEC50:  3.00E+5nMAssay Description:Subconfluent human lung fibroblast cells (MRC-5, American Type Culture Collection, Rockville, Md.) in 24-well plates were treated with drugs diluted ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The Regents Of The University Of California

US Patent
LigandPNGBDBM275775(US10071110, Compound 1-O-octadecylpropanediol-3-CD...)
Affinity DataEC50:  3.00E+4nMAssay Description:Subconfluent human lung fibroblast cells (MRC-5, American Type Culture Collection, Rockville, Md.) in 24-well plates were treated with drugs diluted ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The Regents Of The University Of California

US Patent
LigandPNGBDBM275776(US10071110, Compound 1-O-octadecylpropanediol-3-cC...)
Affinity DataEC50:  3.00E+5nMAssay Description:Subconfluent human lung fibroblast cells (MRC-5, American Type Culture Collection, Rockville, Md.) in 24-well plates were treated with drugs diluted ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The Regents Of The University Of California

US Patent
LigandPNGBDBM275777(US10071110, Compound 1-O-octadecylethanediol-2-CDV)
Affinity DataEC50: >1nMAssay Description:Subconfluent human lung fibroblast cells (MRC-5, American Type Culture Collection, Rockville, Md.) in 24-well plates were treated with drugs diluted ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The Regents Of The University Of California

US Patent
LigandPNGBDBM275778(US10071110, Compound 1-O-octadecylethanediol-2-cCD...)
Affinity DataEC50:  3.00E+5nMAssay Description:Subconfluent human lung fibroblast cells (MRC-5, American Type Culture Collection, Rockville, Md.) in 24-well plates were treated with drugs diluted ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The Regents Of The University Of California

US Patent
LigandPNGBDBM275779(US10071110, Compound Hexadecyl-cCDV)
Affinity DataEC50:  40nMAssay Description:Subconfluent human lung fibroblast cells (MRC-5, American Type Culture Collection, Rockville, Md.) in 24-well plates were treated with drugs diluted ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The Regents Of The University Of California

US Patent
LigandPNGBDBM50001103((2-(6-amino-9H-purin-9-yl)ethoxy)methylphosphonic ...)
Affinity DataEC50:  5.50E+4nMAssay Description:Subconfluent human lung fibroblast cells (MRC-5, American Type Culture Collection, Rockville, Md.) in 24-well plates were treated with drugs diluted ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The Regents Of The University Of California

US Patent
LigandPNGBDBM275780(US10071110, Compound 1-O-hexadecylpropanediol-3-AD...)
Affinity DataEC50:  100nMAssay Description:Subconfluent human lung fibroblast cells (MRC-5, American Type Culture Collection, Rockville, Md.) in 24-well plates were treated with drugs diluted ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The Regents Of The University Of California

US Patent
LigandPNGBDBM275781(US10071110, Compound 1-O-octadecyl-sn-glycero-3-AD...)
Affinity DataEC50:  210nMAssay Description:Subconfluent human lung fibroblast cells (MRC-5, American Type Culture Collection, Rockville, Md.) in 24-well plates were treated with drugs diluted ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The Regents Of The University Of California

US Patent
LigandPNGBDBM275767(US10071110, Compound CDV | US10071110, Compound Ci...)
Affinity DataEC50:  1.80E+3nMAssay Description:The activity of cidofovir (CDV), cyclic cidofovir (cCDV), and 1-O-hexadecylpropanediol-3-cCDV (HDP-cCDV) were tested for antiviral activity in human ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The Regents Of The University Of California

US Patent
LigandPNGBDBM275767(US10071110, Compound CDV | US10071110, Compound Ci...)
Affinity DataEC50:  2.10E+3nMAssay Description:The activity of cidofovir (CDV), cyclic cidofovir (cCDV), and 1-O-hexadecylpropanediol-3-cCDV (HDP-cCDV) were tested for antiviral activity in human ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The Regents Of The University Of California

US Patent
LigandPNGBDBM275768(CYCLIC CIDOFOVIR | Cyclic-hpmpc | US10071110, Comp...)
Affinity DataEC50:  970nMAssay Description:The activity of cidofovir (CDV), cyclic cidofovir (cCDV), and 1-O-hexadecylpropanediol-3-cCDV (HDP-cCDV) were tested for antiviral activity in human ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The Regents Of The University Of California

US Patent
LigandPNGBDBM275768(CYCLIC CIDOFOVIR | Cyclic-hpmpc | US10071110, Comp...)
Affinity DataEC50:  720nMAssay Description:The activity of cidofovir (CDV), cyclic cidofovir (cCDV), and 1-O-hexadecylpropanediol-3-cCDV (HDP-cCDV) were tested for antiviral activity in human ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The Regents Of The University Of California

US Patent
LigandPNGBDBM275769(Hexadecyloxypropyl-cyclic cidofovir | US10071110, ...)
Affinity DataEC50:  110nMAssay Description:The activity of cidofovir (CDV), cyclic cidofovir (cCDV), and 1-O-hexadecylpropanediol-3-cCDV (HDP-cCDV) were tested for antiviral activity in human ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The Regents Of The University Of California

US Patent
LigandPNGBDBM275769(Hexadecyloxypropyl-cyclic cidofovir | US10071110, ...)
Affinity DataEC50: <30nMAssay Description:The activity of cidofovir (CDV), cyclic cidofovir (cCDV), and 1-O-hexadecylpropanediol-3-cCDV (HDP-cCDV) were tested for antiviral activity in human ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHIV-1 protease(Human immunodeficiency virus)
The Regents Of The University Of California

US Patent
LigandPNGBDBM50002692((AZT) 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-...)
Affinity DataEC50:  7nMAssay Description:Preliminary experiments in the inhibition of HIV-1 replication by invention compounds were performed as follows. Drug assays were carried out as prev...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHIV-1 protease(Human immunodeficiency virus)
The Regents Of The University Of California

US Patent
LigandPNGBDBM50001103((2-(6-amino-9H-purin-9-yl)ethoxy)methylphosphonic ...)
Affinity DataEC50:  1.60E+4nMAssay Description:Preliminary experiments in the inhibition of HIV-1 replication by invention compounds were performed as follows. Drug assays were carried out as prev...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHIV-1 protease(Human immunodeficiency virus)
The Regents Of The University Of California

US Patent
LigandPNGBDBM275783(US10071110, Compound HDP-ADV)
Affinity DataEC50:  0.100nMAssay Description:Preliminary experiments in the inhibition of HIV-1 replication by invention compounds were performed as follows. Drug assays were carried out as prev...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHIV-1 protease(Human immunodeficiency virus)
The Regents Of The University Of California

US Patent
LigandPNGBDBM31915(CDV | Cidofovir | HPMPC | US10071110, Compound Cid...)
Affinity DataEC50:  1.20E+3nMAssay Description:Subconfluent MRC-5 cells in 24-well culture dishes were inoculated by removing the medium and adding HSV-1 virus at a dilution that will result in a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHIV-1 protease(Human immunodeficiency virus)
The Regents Of The University Of California

US Patent
LigandPNGBDBM275768(CYCLIC CIDOFOVIR | Cyclic-hpmpc | US10071110, Comp...)
Affinity DataEC50:  2.10E+3nMAssay Description:Subconfluent MRC-5 cells in 24-well culture dishes were inoculated by removing the medium and adding HSV-1 virus at a dilution that will result in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHIV-1 protease(Human immunodeficiency virus)
The Regents Of The University Of California

US Patent
LigandPNGBDBM275773(US10071110, Compound 1-O-hexadecylpropanediol-3-CD...)
Affinity DataEC50:  400nMAssay Description:Subconfluent MRC-5 cells in 24-well culture dishes were inoculated by removing the medium and adding HSV-1 virus at a dilution that will result in a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHIV-1 protease(Human immunodeficiency virus)
The Regents Of The University Of California

US Patent
LigandPNGBDBM275769(Hexadecyloxypropyl-cyclic cidofovir | US10071110, ...)
Affinity DataEC50:  30nMAssay Description:Subconfluent MRC-5 cells in 24-well culture dishes were inoculated by removing the medium and adding HSV-1 virus at a dilution that will result in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHIV-1 protease(Human immunodeficiency virus)
The Regents Of The University Of California

US Patent
LigandPNGBDBM275775(US10071110, Compound 1-O-octadecylpropanediol-3-CD...)
Affinity DataEC50:  3nMAssay Description:Subconfluent MRC-5 cells in 24-well culture dishes were inoculated by removing the medium and adding HSV-1 virus at a dilution that will result in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHIV-1 protease(Human immunodeficiency virus)
The Regents Of The University Of California

US Patent
LigandPNGBDBM275776(US10071110, Compound 1-O-octadecylpropanediol-3-cC...)
Affinity DataEC50:  330nMAssay Description:Subconfluent MRC-5 cells in 24-well culture dishes were inoculated by removing the medium and adding HSV-1 virus at a dilution that will result in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHIV-1 protease(Human immunodeficiency virus)
The Regents Of The University Of California

US Patent
LigandPNGBDBM275785(US10071110, Compound 1-O-octadecylpropanediol-2-CD...)
Affinity DataEC50:  2nMAssay Description:Subconfluent MRC-5 cells in 24-well culture dishes were inoculated by removing the medium and adding HSV-1 virus at a dilution that will result in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
The Regents Of The University Of California

US Patent
LigandPNGBDBM275768(CYCLIC CIDOFOVIR | Cyclic-hpmpc | US10071110, Comp...)
Affinity DataEC50:  470nMAssay Description:Antiviral assays for HCMV DNA were carried out by DNA hybridization as reported by Dankner, W. M., Scholl, D., Stanat, S. C., Martin, M., Souke, R. L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent