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Patent code US10071984

Compile Data Set for Download or QSAR
Found 129 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Homo sapiens lysine demethylase 2A (KDM2A)


(Homo sapiens (human))
BDBM276087
PNG
(1-(4-chlorophenyl)-4-{1H-[1,2,3]triazolo[4,5-c]pyr...)
Show SMILES Clc1ccc(cc1)-n1cnc(c1)-c1cc2[nH]nnc2cn1
UniProtKB/SwissProt
UniProtKB/TrEMBL

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n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL11 was determined in 384-well plate format under the following reaction conditions: 0.15...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276043
PNG
(2-[1-(1-phenylethyl)imidazol-4-yl]-4-(1H-triazol-4...)
Show SMILES CC(c1ccccc1)n1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1
UniProtKB/SwissProt

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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2A (KDM2A)


(Homo sapiens (human))
BDBM276045
PNG
(2-[1-[2-(2-methoxyphenyl)ethyl]imidazol-4-yl]-4-(1...)
Show SMILES COc1ccccc1CCn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1
UniProtKB/SwissProt
UniProtKB/TrEMBL

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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL11 was determined in 384-well plate format under the following reaction conditions: 0.15...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276047
PNG
(2-[1-[2-(2-ethoxyphenyl)ethyl]imidazol-4-yl]-4-(1H...)
Show SMILES CCOc1ccccc1CCn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1
UniProtKB/SwissProt

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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276067
PNG
(2-[1-[(3-chloro-2-fluorophenyl)methyl]imidazol-4-y...)
Show SMILES Fc1c(Cl)cccc1Cn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1
UniProtKB/SwissProt

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n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276068
PNG
(2-[1-[(2-fluoro-3-methoxyphenyl)methyl]imidazol-4-...)
Show SMILES COc1cccc(Cn2cnc(c2)-c2cc(ccn2)-c2c[nH]nn2)c1F
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n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276077
PNG
(4-[2-[5-[2-(cyclopropylmethoxy)-4-fluorophenyl]-1-...)
Show SMILES Cn1cnc(c1-c1ccc(F)cc1OCC1CC1)-c1cc(ccn1)-c1nn[nH]c1[N+]#[C-]
UniProtKB/SwissProt

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n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276082
PNG
(1-benzyl-4-{1H-[1,2,3]triazolo[4,5-c]pyridin-6-yl}...)
Show SMILES C(c1ccccc1)n1cnc(c1)-c1cc2[nH]nnc2cn1
UniProtKB/SwissProt

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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2A (KDM2A)


(Homo sapiens (human))
BDBM276084
PNG
(1-[(3-chlorophenyl)methyl]-4-{1H-[1,2,3]triazolo[4...)
Show SMILES Clc1cccc(Cn2cnc(c2)-c2cc3[nH]nnc3cn2)c1
UniProtKB/SwissProt
UniProtKB/TrEMBL

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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL11 was determined in 384-well plate format under the following reaction conditions: 0.15...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276087
PNG
(1-(4-chlorophenyl)-4-{1H-[1,2,3]triazolo[4,5-c]pyr...)
Show SMILES Clc1ccc(cc1)-n1cnc(c1)-c1cc2[nH]nnc2cn1
UniProtKB/SwissProt

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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276044
PNG
(2-[1-[2-(2-chlorophenyl)ethyl]imidazol-4-yl]-4-(1H...)
Show SMILES Clc1ccccc1CCn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1
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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276052
PNG
(4-[2-[1-[(2,3-dichlorophenyl)methyl]imidazol-4-yl]...)
Show SMILES Clc1cccc(Cn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C#N)c1Cl
UniProtKB/SwissProt

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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276058
PNG
(2-[1-[(2,3-dichlorophenyl)methyl]imidazol-4-yl]-4-...)
Show SMILES Fc1[nH]nnc1-c1ccnc(c1)-c1cn(Cc2cccc(Cl)c2Cl)cn1
UniProtKB/SwissProt

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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2A (KDM2A)


(Homo sapiens (human))
BDBM276061
PNG
(2-[1-(2-naphthalen-1-ylethyl)imidazol-4-yl]-4-(1H-...)
Show SMILES C(Cn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1)c1cccc2ccccc12
UniProtKB/SwissProt
UniProtKB/TrEMBL

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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL11 was determined in 384-well plate format under the following reaction conditions: 0.15...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276069
PNG
(4-(1H-triazol-4-yl)-2-[1-[2-[2-(trifluoromethyl)ph...)
Show SMILES FC(F)(F)c1ccccc1CCn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1
UniProtKB/SwissProt

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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2A (KDM2A)


(Homo sapiens (human))
BDBM276082
PNG
(1-benzyl-4-{1H-[1,2,3]triazolo[4,5-c]pyridin-6-yl}...)
Show SMILES C(c1ccccc1)n1cnc(c1)-c1cc2[nH]nnc2cn1
UniProtKB/SwissProt
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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL11 was determined in 384-well plate format under the following reaction conditions: 0.15...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276040
PNG
(2-[1-[(2-chlorophenyl)methyl]imidazol-4-yl]-4-(1H-...)
Show SMILES Clc1ccccc1Cn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1
UniProtKB/SwissProt

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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276044
PNG
(2-[1-[2-(2-chlorophenyl)ethyl]imidazol-4-yl]-4-(1H...)
Show SMILES Clc1ccccc1CCn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1
UniProtKB/SwissProt

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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276046
PNG
(2-[1-(1,2,3,4-tetrahydronaphthalen-1-ylmethyl)imid...)
Show SMILES C(C1CCCc2ccccc12)n1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1
UniProtKB/SwissProt

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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2A (KDM2A)


(Homo sapiens (human))
BDBM276047
PNG
(2-[1-[2-(2-ethoxyphenyl)ethyl]imidazol-4-yl]-4-(1H...)
Show SMILES CCOc1ccccc1CCn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1
UniProtKB/SwissProt
UniProtKB/TrEMBL

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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL11 was determined in 384-well plate format under the following reaction conditions: 0.15...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276051
PNG
(4-[2-[1-[(2-chlorophenyl)methyl]imidazol-4-yl]pyri...)
Show SMILES Clc1ccccc1Cn1cnc(c1)-c1cc(ccn1)-c1nn[nH]c1C#N
UniProtKB/SwissProt

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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276053
PNG
(4-[2-[1-(1,2,3,4-tetrahydronaphthalen-1-ylmethyl)i...)
Show SMILES N#Cc1[nH]nnc1-c1ccnc(c1)-c1cn(CC2CCCc3ccccc23)cn1
UniProtKB/SwissProt

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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276055
PNG
(2-[1-[2-(2-phenylmethoxyphenyl)ethyl]imidazol-4-yl...)
Show SMILES C(Cn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1)c1ccccc1OCc1ccccc1
UniProtKB/SwissProt

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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276060
PNG
(2-[1-[[2-chloro-3-(trifluoromethyl)phenyl]methyl]i...)
Show SMILES FC(F)(F)c1cccc(Cn2cnc(c2)-c2cc(ccn2)-c2c[nH]nn2)c1Cl
UniProtKB/SwissProt

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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276073
PNG
(4-(5-fluoro-1H-triazol-4-yl)-2-[1-(2-naphthalen-1-...)
Show SMILES Fc1[nH]nnc1-c1ccnc(c1)-c1cn(CCc2cccc3ccccc23)cn1
UniProtKB/SwissProt

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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2A (KDM2A)


(Homo sapiens (human))
BDBM276083
PNG
(1-[(2-chlorophenyl)methyl]-4-{1H-[1,2,3]triazolo[4...)
Show SMILES Clc1ccccc1Cn1cnc(c1)-c1cc2[nH]nnc2cn1
UniProtKB/SwissProt
UniProtKB/TrEMBL

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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL11 was determined in 384-well plate format under the following reaction conditions: 0.15...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2A (KDM2A)


(Homo sapiens (human))
BDBM276044
PNG
(2-[1-[2-(2-chlorophenyl)ethyl]imidazol-4-yl]-4-(1H...)
Show SMILES Clc1ccccc1CCn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1
UniProtKB/SwissProt
UniProtKB/TrEMBL

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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL11 was determined in 384-well plate format under the following reaction conditions: 0.15...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276045
PNG
(2-[1-[2-(2-methoxyphenyl)ethyl]imidazol-4-yl]-4-(1...)
Show SMILES COc1ccccc1CCn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1
UniProtKB/SwissProt

GoogleScholar
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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2A (KDM2A)


(Homo sapiens (human))
BDBM276060
PNG
(2-[1-[[2-chloro-3-(trifluoromethyl)phenyl]methyl]i...)
Show SMILES FC(F)(F)c1cccc(Cn2cnc(c2)-c2cc(ccn2)-c2c[nH]nn2)c1Cl
UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL11 was determined in 384-well plate format under the following reaction conditions: 0.15...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276066
PNG
(2-[1-[(2-fluoro-3-methylphenyl)methyl]imidazol-4-y...)
Show SMILES Cc1cccc(Cn2cnc(c2)-c2cc(ccn2)-c2c[nH]nn2)c1F
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276070
PNG
(2-[1-[2-(2-chlorophenyl)-2-methylpropyl]imidazol-4...)
Show SMILES CC(C)(Cn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1)c1ccccc1Cl
UniProtKB/SwissProt

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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276072
PNG
(4-(1H-triazol-4-yl)-2-[1-[2-[2-(trifluoromethoxy)p...)
Show SMILES FC(F)(F)Oc1ccccc1CCn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1
UniProtKB/SwissProt

GoogleScholar
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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276075
PNG
(2-[1-(2-naphthalen-1-ylethyl)imidazol-4-yl]-4-[5-(...)
Show SMILES FC(F)(F)c1[nH]nnc1-c1ccnc(c1)-c1cn(CCc2cccc3ccccc23)cn1
UniProtKB/SwissProt

GoogleScholar
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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276079
PNG
(2-[5-[2-(cyclopropylmethoxy)-4-fluorophenyl]-1-met...)
Show SMILES Cn1cnc(c1-c1ccc(F)cc1OCC1CC1)-c1cc(ccn1)-c1nn[nH]c1F
UniProtKB/SwissProt

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n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276080
PNG
(1-(cyclopropylmethyl)-4-{1H-[1,2,3]triazolo[4,5-c]...)
Show SMILES C(C1CC1)n1cnc(c1)-c1cc2[nH]nnc2cn1
UniProtKB/SwissProt

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n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276049
PNG
(2-[1-[2-[2-(cyclopropylmethoxy)phenyl]ethyl]imidaz...)
Show SMILES C(Cn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1)c1ccccc1OCC1CC1
UniProtKB/SwissProt

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n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276050
PNG
(2-[1-(3,4-dihydro-2H-chromen-4-ylmethyl)imidazol-4...)
Show SMILES C(C1CCOc2ccccc12)n1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1
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n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276054
PNG
(4-[2-[1-(2-naphthalen-1-ylethyl)imidazol-4-yl]pyri...)
Show SMILES N#Cc1[nH]nnc1-c1ccnc(c1)-c1cn(CCc2cccc3ccccc23)cn1
UniProtKB/SwissProt

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n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276057
PNG
(2-[1-[(2,3-dichlorophenyl)methyl]imidazol-4-yl]-4-...)
Show SMILES Clc1cccc(Cn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2I)c1Cl
UniProtKB/SwissProt

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n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2A (KDM2A)


(Homo sapiens (human))
BDBM276059
PNG
(2-[1-[(2,3-dichlorophenyl)methyl]imidazol-4-yl]-4-...)
Show SMILES Clc1cccc(Cn2cnc(c2)-c2cc(ccn2)-c2c[nH]nn2)c1Cl
UniProtKB/SwissProt
UniProtKB/TrEMBL

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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL11 was determined in 384-well plate format under the following reaction conditions: 0.15...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276062
PNG
(2-[5-(4-fluoro-3-methoxyphenyl)-1-methylimidazol-4...)
Show SMILES COc1cc(ccc1F)-c1c(ncn1C)-c1cc(ccn1)-c1c[nH]nn1
UniProtKB/SwissProt

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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276063
PNG
(2-[5-(3-ethoxy-4-fluorophenyl)-1-methylimidazol-4-...)
Show SMILES CCOc1cc(ccc1F)-c1c(ncn1C)-c1cc(ccn1)-c1c[nH]nn1
UniProtKB/SwissProt

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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276074
PNG
(4-(5-chloro-1H-triazol-4-yl)-2-[1-(2-naphthalen-1-...)
Show SMILES Clc1[nH]nnc1-c1ccnc(c1)-c1cn(CCc2cccc3ccccc23)cn1
UniProtKB/SwissProt

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n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276076
PNG
(4-(5-iodo-1H-triazol-4-yl)-2-[1-(2-naphthalen-1-yl...)
Show SMILES Ic1[nH]nnc1-c1ccnc(c1)-c1cn(CCc2cccc3ccccc23)cn1
UniProtKB/SwissProt

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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276085
PNG
(1-[(4-chlorophenyl)methyl]-4-{1H-[1,2,3]triazolo[4...)
Show SMILES Clc1ccc(Cn2cnc(c2)-c2cc3[nH]nnc3cn2)cc1
UniProtKB/SwissProt

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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276086
PNG
(1-[(3,4-dichlorophenyl)methyl]-4-{1H-[1,2,3]triazo...)
Show SMILES Clc1ccc(Cn2cnc(c2)-c2cc3[nH]nnc3cn2)cc1Cl
UniProtKB/SwissProt

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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276088
PNG
(1-(2-chlorophenyl)-4-{1H-[1,2,3]triazolo[4,5-c]pyr...)
Show SMILES Clc1ccccc1-n1cnc(c1)-c1cc2[nH]nnc2cn1
UniProtKB/SwissProt

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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2A (KDM2A)


(Homo sapiens (human))
BDBM276088
PNG
(1-(2-chlorophenyl)-4-{1H-[1,2,3]triazolo[4,5-c]pyr...)
Show SMILES Clc1ccccc1-n1cnc(c1)-c1cc2[nH]nnc2cn1
UniProtKB/SwissProt
UniProtKB/TrEMBL

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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL11 was determined in 384-well plate format under the following reaction conditions: 0.15...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276093
PNG
(2-(5-bromo-1-(2-chlorobenzyl)-1H-imidazol-4-yl)-4-...)
Show SMILES Clc1ccccc1Cn1cnc(c1Br)-c1cc(ccn1)-c1cn[nH]n1
UniProtKB/SwissProt

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n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276041
PNG
(2-[5-(4-fluorophenyl)-1-methylimidazol-4-yl]-4-(1H...)
Show SMILES Cn1cnc(c1-c1ccc(F)cc1)-c1cc(ccn1)-c1c[nH]nn1
UniProtKB/SwissProt

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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2A (KDM2A)


(Homo sapiens (human))
BDBM276042
PNG
(2-[5-[2-(cyclopropylmethoxy)-4-fluorophenyl]-1-met...)
Show SMILES Cn1cnc(c1-c1ccc(F)cc1OCC1CC1)-c1cc(ccn1)-c1c[nH]nn1
UniProtKB/SwissProt
UniProtKB/TrEMBL

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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL11 was determined in 384-well plate format under the following reaction conditions: 0.15...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276059
PNG
(2-[1-[(2,3-dichlorophenyl)methyl]imidazol-4-yl]-4-...)
Show SMILES Clc1cccc(Cn2cnc(c2)-c2cc(ccn2)-c2c[nH]nn2)c1Cl
UniProtKB/SwissProt

GoogleScholar
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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276067
PNG
(2-[1-[(3-chloro-2-fluorophenyl)methyl]imidazol-4-y...)
Show SMILES Fc1c(Cl)cccc1Cn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1
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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276078
PNG
(4-(5-chloro-1H-triazol-4-yl)-2-[5-[2-(cyclopropylm...)
Show SMILES Cn1cnc(c1-c1ccc(F)cc1OCC1CC1)-c1cc(ccn1)-c1nn[nH]c1Cl
UniProtKB/SwissProt

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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2A (KDM2A)


(Homo sapiens (human))
BDBM276085
PNG
(1-[(4-chlorophenyl)methyl]-4-{1H-[1,2,3]triazolo[4...)
Show SMILES Clc1ccc(Cn2cnc(c2)-c2cc3[nH]nnc3cn2)cc1
UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL11 was determined in 384-well plate format under the following reaction conditions: 0.15...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2A (KDM2A)


(Homo sapiens (human))
BDBM276086
PNG
(1-[(3,4-dichlorophenyl)methyl]-4-{1H-[1,2,3]triazo...)
Show SMILES Clc1ccc(Cn2cnc(c2)-c2cc3[nH]nnc3cn2)cc1Cl
UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL11 was determined in 384-well plate format under the following reaction conditions: 0.15...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2A (KDM2A)


(Homo sapiens (human))
BDBM276043
PNG
(2-[1-(1-phenylethyl)imidazol-4-yl]-4-(1H-triazol-4...)
Show SMILES CC(c1ccccc1)n1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1
UniProtKB/SwissProt
UniProtKB/TrEMBL

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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL11 was determined in 384-well plate format under the following reaction conditions: 0.15...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2A (KDM2A)


(Homo sapiens (human))
BDBM276046
PNG
(2-[1-(1,2,3,4-tetrahydronaphthalen-1-ylmethyl)imid...)
Show SMILES C(C1CCCc2ccccc12)n1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1
UniProtKB/SwissProt
UniProtKB/TrEMBL

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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL11 was determined in 384-well plate format under the following reaction conditions: 0.15...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276048
PNG
(4-(1H-triazol-4-yl)-2-[1-[2-[2-(2,2,2-trifluoroeth...)
Show SMILES FC(F)(F)COc1ccccc1CCn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1
UniProtKB/SwissProt

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n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276050
PNG
(2-[1-(3,4-dihydro-2H-chromen-4-ylmethyl)imidazol-4...)
Show SMILES C(C1CCOc2ccccc12)n1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1
UniProtKB/SwissProt

GoogleScholar
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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276056
PNG
(2-[1-[2-(2-phenoxyphenyl)ethyl]imidazol-4-yl]-4-(1...)
Show SMILES C(Cn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1)c1ccccc1Oc1ccccc1
UniProtKB/SwissProt

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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276061
PNG
(2-[1-(2-naphthalen-1-ylethyl)imidazol-4-yl]-4-(1H-...)
Show SMILES C(Cn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1)c1cccc2ccccc12
UniProtKB/SwissProt

GoogleScholar
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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276042
PNG
(2-[5-[2-(cyclopropylmethoxy)-4-fluorophenyl]-1-met...)
Show SMILES Cn1cnc(c1-c1ccc(F)cc1OCC1CC1)-c1cc(ccn1)-c1c[nH]nn1
UniProtKB/SwissProt

GoogleScholar
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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276083
PNG
(1-[(2-chlorophenyl)methyl]-4-{1H-[1,2,3]triazolo[4...)
Show SMILES Clc1ccccc1Cn1cnc(c1)-c1cc2[nH]nnc2cn1
UniProtKB/SwissProt

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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276084
PNG
(1-[(3-chlorophenyl)methyl]-4-{1H-[1,2,3]triazolo[4...)
Show SMILES Clc1cccc(Cn2cnc(c2)-c2cc3[nH]nnc3cn2)c1
UniProtKB/SwissProt

GoogleScholar
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UniChem
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276041
PNG
(2-[5-(4-fluorophenyl)-1-methylimidazol-4-yl]-4-(1H...)
Show SMILES Cn1cnc(c1-c1ccc(F)cc1)-c1cc(ccn1)-c1c[nH]nn1
GoogleScholar
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UniChem
n/an/a 550n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276060
PNG
(2-[1-[[2-chloro-3-(trifluoromethyl)phenyl]methyl]i...)
Show SMILES FC(F)(F)c1cccc(Cn2cnc(c2)-c2cc(ccn2)-c2c[nH]nn2)c1Cl
GoogleScholar
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UniChem
n/an/a 550n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276066
PNG
(2-[1-[(2-fluoro-3-methylphenyl)methyl]imidazol-4-y...)
Show SMILES Cc1cccc(Cn2cnc(c2)-c2cc(ccn2)-c2c[nH]nn2)c1F
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UniChem
n/an/a 550n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2A (KDM2A)


(Homo sapiens (human))
BDBM276089
PNG
(1-(3-chlorophenyl)-4-{1H-[1,2,3]triazolo[4,5-c]pyr...)
Show SMILES Clc1cccc(c1)-n1cnc(c1)-c1cc2[nH]nnc2cn1
UniProtKB/SwissProt
UniProtKB/TrEMBL

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UniChem
n/an/a 550n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL11 was determined in 384-well plate format under the following reaction conditions: 0.15...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276092
PNG
(5-[2-(cyclopropylmethoxy)-4-fluorophenyl]-1-methyl...)
Show SMILES Cn1cnc(c1-c1ccc(F)cc1OCC1CC1)-c1cc2[nH]nnc2cn1
UniProtKB/SwissProt

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n/an/a 550n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276048
PNG
(4-(1H-triazol-4-yl)-2-[1-[2-[2-(2,2,2-trifluoroeth...)
Show SMILES FC(F)(F)COc1ccccc1CCn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1
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UniChem
n/an/a 550n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276053
PNG
(4-[2-[1-(1,2,3,4-tetrahydronaphthalen-1-ylmethyl)i...)
Show SMILES N#Cc1[nH]nnc1-c1ccnc(c1)-c1cn(CC2CCCc3ccccc23)cn1
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UniChem
n/an/a 550n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276058
PNG
(2-[1-[(2,3-dichlorophenyl)methyl]imidazol-4-yl]-4-...)
Show SMILES Fc1[nH]nnc1-c1ccnc(c1)-c1cn(Cc2cccc(Cl)c2Cl)cn1
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UniChem
n/an/a 550n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276090
PNG
(1-(3,5-dichlorophenyl)-4-{1H-[1,2,3]triazolo[4,5-c...)
Show SMILES Clc1cc(Cl)cc(c1)-n1cnc(c1)-c1cc2[nH]nnc2cn1
UniProtKB/SwissProt

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UniChem
n/an/a 550n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276043
PNG
(2-[1-(1-phenylethyl)imidazol-4-yl]-4-(1H-triazol-4...)
Show SMILES CC(c1ccccc1)n1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1
GoogleScholar
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UniChem
n/an/a 550n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276054
PNG
(4-[2-[1-(2-naphthalen-1-ylethyl)imidazol-4-yl]pyri...)
Show SMILES N#Cc1[nH]nnc1-c1ccnc(c1)-c1cn(CCc2cccc3ccccc23)cn1
GoogleScholar
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UniChem
n/an/a 550n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276057
PNG
(2-[1-[(2,3-dichlorophenyl)methyl]imidazol-4-yl]-4-...)
Show SMILES Clc1cccc(Cn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2I)c1Cl
GoogleScholar
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UniChem
n/an/a 550n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276061
PNG
(2-[1-(2-naphthalen-1-ylethyl)imidazol-4-yl]-4-(1H-...)
Show SMILES C(Cn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1)c1cccc2ccccc12
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UniChem
n/an/a 550n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276064
PNG
(2-[1-[[2-fluoro-3-(trifluoromethoxy)phenyl]methyl]...)
Show SMILES Fc1c(Cn2cnc(c2)-c2cc(ccn2)-c2c[nH]nn2)cccc1OC(F)(F)F
UniProtKB/SwissProt

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UniChem
n/an/a 550n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276070
PNG
(2-[1-[2-(2-chlorophenyl)-2-methylpropyl]imidazol-4...)
Show SMILES CC(C)(Cn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1)c1ccccc1Cl
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UniChem
n/an/a 550n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2A (KDM2A)


(Homo sapiens (human))
BDBM276040
PNG
(2-[1-[(2-chlorophenyl)methyl]imidazol-4-yl]-4-(1H-...)
Show SMILES Clc1ccccc1Cn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1
UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
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UniChem
n/an/a 550n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL11 was determined in 384-well plate format under the following reaction conditions: 0.15...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276046
PNG
(2-[1-(1,2,3,4-tetrahydronaphthalen-1-ylmethyl)imid...)
Show SMILES C(C1CCCc2ccccc12)n1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1
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UniChem
n/an/a 550n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276059
PNG
(2-[1-[(2,3-dichlorophenyl)methyl]imidazol-4-yl]-4-...)
Show SMILES Clc1cccc(Cn2cnc(c2)-c2cc(ccn2)-c2c[nH]nn2)c1Cl
GoogleScholar
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UniChem
n/an/a 550n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276062
PNG
(2-[5-(4-fluoro-3-methoxyphenyl)-1-methylimidazol-4...)
Show SMILES COc1cc(ccc1F)-c1c(ncn1C)-c1cc(ccn1)-c1c[nH]nn1
GoogleScholar
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UniChem
n/an/a 550n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276065
PNG
(2-[1-[2-(2-phenylphenyl)ethyl]imidazol-4-yl]-4-(1H...)
Show SMILES C(Cn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1)c1ccccc1-c1ccccc1
UniProtKB/SwissProt

GoogleScholar
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UniChem
n/an/a 550n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276093
PNG
(2-(5-bromo-1-(2-chlorobenzyl)-1H-imidazol-4-yl)-4-...)
Show SMILES Clc1ccccc1Cn1cnc(c1Br)-c1cc(ccn1)-c1cn[nH]n1
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UniChem
n/an/a 550n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276045
PNG
(2-[1-[2-(2-methoxyphenyl)ethyl]imidazol-4-yl]-4-(1...)
Show SMILES COc1ccccc1CCn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1
GoogleScholar
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UniChem
n/an/a 550n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276047
PNG
(2-[1-[2-(2-ethoxyphenyl)ethyl]imidazol-4-yl]-4-(1H...)
Show SMILES CCOc1ccccc1CCn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1
GoogleScholar
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UniChem
n/an/a 550n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276049
PNG
(2-[1-[2-[2-(cyclopropylmethoxy)phenyl]ethyl]imidaz...)
Show SMILES C(Cn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1)c1ccccc1OCC1CC1
GoogleScholar
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UniChem
n/an/a 550n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2A (KDM2A)


(Homo sapiens (human))
BDBM276063
PNG
(2-[5-(3-ethoxy-4-fluorophenyl)-1-methylimidazol-4-...)
Show SMILES CCOc1cc(ccc1F)-c1c(ncn1C)-c1cc(ccn1)-c1c[nH]nn1
UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
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UniChem
n/an/a 550n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL11 was determined in 384-well plate format under the following reaction conditions: 0.15...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276068
PNG
(2-[1-[(2-fluoro-3-methoxyphenyl)methyl]imidazol-4-...)
Show SMILES COc1cccc(Cn2cnc(c2)-c2cc(ccn2)-c2c[nH]nn2)c1F
GoogleScholar
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UniChem
n/an/a 550n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276069
PNG
(4-(1H-triazol-4-yl)-2-[1-[2-[2-(trifluoromethyl)ph...)
Show SMILES FC(F)(F)c1ccccc1CCn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1
GoogleScholar
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UniChem
n/an/a 550n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276081
PNG
(4-{1H-[1,2,3]triazolo[4,5-c]pyridin-6-yl}-1-(2,2,2...)
Show SMILES FC(F)(F)Cn1cnc(c1)-c1cc2[nH]nnc2cn1
UniProtKB/SwissProt

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UniChem
n/an/a 550n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276082
PNG
(1-benzyl-4-{1H-[1,2,3]triazolo[4,5-c]pyridin-6-yl}...)
Show SMILES C(c1ccccc1)n1cnc(c1)-c1cc2[nH]nnc2cn1
GoogleScholar
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UniChem
n/an/a 550n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276072
PNG
(4-(1H-triazol-4-yl)-2-[1-[2-[2-(trifluoromethoxy)p...)
Show SMILES FC(F)(F)Oc1ccccc1CCn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1
GoogleScholar
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UniChem
n/an/a 550n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276089
PNG
(1-(3-chlorophenyl)-4-{1H-[1,2,3]triazolo[4,5-c]pyr...)
Show SMILES Clc1cccc(c1)-n1cnc(c1)-c1cc2[nH]nnc2cn1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 550n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276039
PNG
(2-(1-methylimidazol-4-yl)-4-(1H-triazol-4-yl)pyrid...)
Show SMILES Cn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1
UniProtKB/SwissProt

GoogleScholar
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UniChem
n/an/a 550n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276039
PNG
(2-(1-methylimidazol-4-yl)-4-(1H-triazol-4-yl)pyrid...)
Show SMILES Cn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1
GoogleScholar
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UniChem
n/an/a 550n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276040
PNG
(2-[1-[(2-chlorophenyl)methyl]imidazol-4-yl]-4-(1H-...)
Show SMILES Clc1ccccc1Cn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1
GoogleScholar
AffyNet 
UniChem
n/an/a 550n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276071
PNG
(2-[1-(1-phenylpropan-2-yl)imidazol-4-yl]-4-(1H-tri...)
Show SMILES CC(Cc1ccccc1)n1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 550n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276073
PNG
(4-(5-fluoro-1H-triazol-4-yl)-2-[1-(2-naphthalen-1-...)
Show SMILES Fc1[nH]nnc1-c1ccnc(c1)-c1cn(CCc2cccc3ccccc23)cn1
GoogleScholar
AffyNet 
UniChem
n/an/a 550n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276091
PNG
(5-(4-fluorophenyl)-1-methyl-4-{1H-[1,2,3]triazolo[...)
Show SMILES Cn1cnc(c1-c1ccc(F)cc1)-c1cc2[nH]nnc2cn1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 550n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276051
PNG
(4-[2-[1-[(2-chlorophenyl)methyl]imidazol-4-yl]pyri...)
Show SMILES Clc1ccccc1Cn1cnc(c1)-c1cc(ccn1)-c1nn[nH]c1C#N
GoogleScholar
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UniChem
n/an/a 5.50E+3n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276063
PNG
(2-[5-(3-ethoxy-4-fluorophenyl)-1-methylimidazol-4-...)
Show SMILES CCOc1cc(ccc1F)-c1c(ncn1C)-c1cc(ccn1)-c1c[nH]nn1
GoogleScholar
AffyNet 
UniChem
n/an/a 5.50E+3n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276089
PNG
(1-(3-chlorophenyl)-4-{1H-[1,2,3]triazolo[4,5-c]pyr...)
Show SMILES Clc1cccc(c1)-n1cnc(c1)-c1cc2[nH]nnc2cn1
GoogleScholar
AffyNet 
UniChem
n/an/a 5.50E+3n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276081
PNG
(4-{1H-[1,2,3]triazolo[4,5-c]pyridin-6-yl}-1-(2,2,2...)
Show SMILES FC(F)(F)Cn1cnc(c1)-c1cc2[nH]nnc2cn1
GoogleScholar
AffyNet 
UniChem
n/an/a 5.50E+3n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276079
PNG
(2-[5-[2-(cyclopropylmethoxy)-4-fluorophenyl]-1-met...)
Show SMILES Cn1cnc(c1-c1ccc(F)cc1OCC1CC1)-c1cc(ccn1)-c1nn[nH]c1F
GoogleScholar
AffyNet 
UniChem
n/an/a 5.50E+3n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276086
PNG
(1-[(3,4-dichlorophenyl)methyl]-4-{1H-[1,2,3]triazo...)
Show SMILES Clc1ccc(Cn2cnc(c2)-c2cc3[nH]nnc3cn2)cc1Cl
GoogleScholar
AffyNet 
UniChem
n/an/a 5.50E+3n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276084
PNG
(1-[(3-chlorophenyl)methyl]-4-{1H-[1,2,3]triazolo[4...)
Show SMILES Clc1cccc(Cn2cnc(c2)-c2cc3[nH]nnc3cn2)c1
GoogleScholar
AffyNet 
UniChem
n/an/a 5.50E+3n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276090
PNG
(1-(3,5-dichlorophenyl)-4-{1H-[1,2,3]triazolo[4,5-c...)
Show SMILES Clc1cc(Cl)cc(c1)-n1cnc(c1)-c1cc2[nH]nnc2cn1
GoogleScholar
AffyNet 
UniChem
n/an/a 5.50E+3n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276080
PNG
(1-(cyclopropylmethyl)-4-{1H-[1,2,3]triazolo[4,5-c]...)
Show SMILES C(C1CC1)n1cnc(c1)-c1cc2[nH]nnc2cn1
GoogleScholar
AffyNet 
UniChem
n/an/a 5.50E+3n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276092
PNG
(5-[2-(cyclopropylmethoxy)-4-fluorophenyl]-1-methyl...)
Show SMILES Cn1cnc(c1-c1ccc(F)cc1OCC1CC1)-c1cc2[nH]nnc2cn1
GoogleScholar
AffyNet 
UniChem
n/an/a 5.50E+3n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276065
PNG
(2-[1-[2-(2-phenylphenyl)ethyl]imidazol-4-yl]-4-(1H...)
Show SMILES C(Cn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1)c1ccccc1-c1ccccc1
GoogleScholar
AffyNet 
UniChem
n/an/a 5.50E+3n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276085
PNG
(1-[(4-chlorophenyl)methyl]-4-{1H-[1,2,3]triazolo[4...)
Show SMILES Clc1ccc(Cn2cnc(c2)-c2cc3[nH]nnc3cn2)cc1
GoogleScholar
AffyNet 
UniChem
n/an/a 5.50E+3n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276042
PNG
(2-[5-[2-(cyclopropylmethoxy)-4-fluorophenyl]-1-met...)
Show SMILES Cn1cnc(c1-c1ccc(F)cc1OCC1CC1)-c1cc(ccn1)-c1c[nH]nn1
GoogleScholar
AffyNet 
UniChem
n/an/a 5.50E+3n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276074
PNG
(4-(5-chloro-1H-triazol-4-yl)-2-[1-(2-naphthalen-1-...)
Show SMILES Clc1[nH]nnc1-c1ccnc(c1)-c1cn(CCc2cccc3ccccc23)cn1
GoogleScholar
AffyNet 
UniChem
n/an/a 5.50E+3n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276077
PNG
(4-[2-[5-[2-(cyclopropylmethoxy)-4-fluorophenyl]-1-...)
Show SMILES Cn1cnc(c1-c1ccc(F)cc1OCC1CC1)-c1cc(ccn1)-c1nn[nH]c1[N+]#[C-]
GoogleScholar
AffyNet 
UniChem
n/an/a 5.50E+3n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276083
PNG
(1-[(2-chlorophenyl)methyl]-4-{1H-[1,2,3]triazolo[4...)
Show SMILES Clc1ccccc1Cn1cnc(c1)-c1cc2[nH]nnc2cn1
GoogleScholar
AffyNet 
UniChem
n/an/a 5.50E+3n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276091
PNG
(5-(4-fluorophenyl)-1-methyl-4-{1H-[1,2,3]triazolo[...)
Show SMILES Cn1cnc(c1-c1ccc(F)cc1)-c1cc2[nH]nnc2cn1
GoogleScholar
AffyNet 
UniChem
n/an/a 5.50E+3n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276055
PNG
(2-[1-[2-(2-phenylmethoxyphenyl)ethyl]imidazol-4-yl...)
Show SMILES C(Cn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1)c1ccccc1OCc1ccccc1
GoogleScholar
AffyNet 
UniChem
n/an/a 5.50E+3n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276071
PNG
(2-[1-(1-phenylpropan-2-yl)imidazol-4-yl]-4-(1H-tri...)
Show SMILES CC(Cc1ccccc1)n1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1
GoogleScholar
AffyNet 
UniChem
n/an/a 5.50E+3n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276087
PNG
(1-(4-chlorophenyl)-4-{1H-[1,2,3]triazolo[4,5-c]pyr...)
Show SMILES Clc1ccc(cc1)-n1cnc(c1)-c1cc2[nH]nnc2cn1
GoogleScholar
AffyNet 
UniChem
n/an/a 5.50E+3n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276088
PNG
(1-(2-chlorophenyl)-4-{1H-[1,2,3]triazolo[4,5-c]pyr...)
Show SMILES Clc1ccccc1-n1cnc(c1)-c1cc2[nH]nnc2cn1
GoogleScholar
AffyNet 
UniChem
n/an/a 5.50E+3n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276052
PNG
(4-[2-[1-[(2,3-dichlorophenyl)methyl]imidazol-4-yl]...)
Show SMILES Clc1cccc(Cn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C#N)c1Cl
GoogleScholar
AffyNet 
UniChem
n/an/a 5.50E+3n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276056
PNG
(2-[1-[2-(2-phenoxyphenyl)ethyl]imidazol-4-yl]-4-(1...)
Show SMILES C(Cn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1)c1ccccc1Oc1ccccc1
GoogleScholar
AffyNet 
UniChem
n/an/a 5.50E+3n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276064
PNG
(2-[1-[[2-fluoro-3-(trifluoromethoxy)phenyl]methyl]...)
Show SMILES Fc1c(Cn2cnc(c2)-c2cc(ccn2)-c2c[nH]nn2)cccc1OC(F)(F)F
GoogleScholar
AffyNet 
UniChem
n/an/a 5.50E+3n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276075
PNG
(2-[1-(2-naphthalen-1-ylethyl)imidazol-4-yl]-4-[5-(...)
Show SMILES FC(F)(F)c1[nH]nnc1-c1ccnc(c1)-c1cn(CCc2cccc3ccccc23)cn1
GoogleScholar
AffyNet 
UniChem
n/an/a>1.00E+4n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276076
PNG
(4-(5-iodo-1H-triazol-4-yl)-2-[1-(2-naphthalen-1-yl...)
Show SMILES Ic1[nH]nnc1-c1ccnc(c1)-c1cn(CCc2cccc3ccccc23)cn1
GoogleScholar
AffyNet 
UniChem
n/an/a>1.00E+4n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
histone lysine demethylase PHF8 isoform 2


(Homo sapiens (human))
BDBM276078
PNG
(4-(5-chloro-1H-triazol-4-yl)-2-[5-[2-(cyclopropylm...)
Show SMILES Cn1cnc(c1-c1ccc(F)cc1OCC1CC1)-c1cc(ccn1)-c1nn[nH]c1Cl
GoogleScholar
AffyNet 
UniChem
n/an/a>1.00E+4n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%