Compile Data Set for Download or QSAR
maximum 50k data
Found 54 Enz. Inhib. hit(s) with all data for entry = 645
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285498(4-[4-Cyano-2-({[(1R,2R)-6′-(methylcarbamoyl)...)
Affinity DataIC50:  1.20nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285464(4-{4-Cyano-2-[({2′R, 4S)-6-[(1-methyl 1H-pyr...)
Affinity DataIC50:  1.30nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285502(US10077247, Example 20-2)
Affinity DataIC50:  1.60nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285487(4-[4-Cyano-2-({[(2′R,4S)-6-(1H-pyrazol-1-yl)...)
Affinity DataIC50:  2.40nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285480(4-[4-Cyano-2-({[(2′R,4S)-6-(propylcarbamoyl)...)
Affinity DataIC50:  2.5nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285036(US10077247, Example 1)
Affinity DataIC50:  2.5nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285470(4-[4-Cyano-2-({[(2′R,4S)-6-(3-pyridazinylcar...)
Affinity DataIC50:  2.5nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285483(4-[4-Cyano-2-({[(2′R,4S)-6-(5-methyl-1,3,4-o...)
Affinity DataIC50:  2.70nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285500(4-{4-Cyano-2-[({(1R,2R)-6′-[(1-methyl-1H-pyr...)
Affinity DataIC50:  2.70nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285484(US10077247, Example 5)
Affinity DataIC50:  2.80nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285499(4-{4-Cyano-2-[({(1R,2R)-6′-[(2-methoxyethyl)...)
Affinity DataIC50:  3nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285482(4-[4-Cyano-2-({[(2′R,4S)-6-(ethylcarbamoyl)-...)
Affinity DataIC50:  3nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285463(US10077247, Example 2-4)
Affinity DataIC50:  3.30nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285476(US10077247, Example 2-39)
Affinity DataIC50:  3.40nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285478(4-[4-Cyano-2-({[(2′R,4S)-6-(1,2-oxazol-5-ylc...)
Affinity DataIC50:  3.40nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285474(4-[4-Cyano-2-({[(2′R,4S)-6-(1,2-oxazol-3-ylc...)
Affinity DataIC50:  3.40nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285495(4-[4-Cyano-2-({[(2′R,4S)-6-(1-methyl-1H-1,2,...)
Affinity DataIC50:  3.5nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285462(US10077247, Example 2-3)
Affinity DataIC50:  3.5nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285489(4-[4-Cyano-2-({[(2′R,4S)-6-(6-methoxy-3-pyri...)
Affinity DataIC50:  3.5nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285479(4-{4-Cyano-2-[({(2′R,4S)-6-[(1-methyl-1H-pyr...)
Affinity DataIC50:  3.60nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285471(4-{4-Cyano-2-[({(2′R,4S)-6-[(2,2-difluoroeth...)
Affinity DataIC50:  3.70nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285486(4-[4-Cyano-2-({[(2′R,4S)-6-(3-pyridinyl)-2,3...)
Affinity DataIC50:  3.80nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285466(4-[4-cyano-2-({[(2′R,4S)-6-(cyclopropylcarba...)
Affinity DataIC50:  4nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285496(4-[4-Cyano-2-({[(2′R,4S)-6-(3-pyridazinyl)-2...)
Affinity DataIC50:  4.10nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285512(4-[4-Cyano-2-({[(1S,2R)-3′,3′-dimethyl...)
Affinity DataIC50:  4.30nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285508(4-[4-Cyano-2-({[(2′R,3S)-5-(3-pyridinyl)spir...)
Affinity DataIC50:  4.5nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285465(4-{4-Cyano-2-[({(2′R,4S)-6-[(1-methyl-1H-pyr...)
Affinity DataIC50:  4.5nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285468(4-[4 Cyano 2-({[(2′R,4S)-6-(cyclopentylcarba...)
Affinity DataIC50:  4.5nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285469(4-[4-Cyano-2-({[(2′R,4S)-6-(2-pyridinylcarba...)
Affinity DataIC50:  4.5nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285492(4-[4-Cyano-2-({[(2′R,4S)-6-(1H-pyrrolo[2,3-b...)
Affinity DataIC50:  4.5nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285475(US10077247, Example 2-38)
Affinity DataIC50:  4.70nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285461(US10077247, Example 2-2)
Affinity DataIC50:  5.30nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285511(4-[4-Cyano-2-({[(1S,2R)-6′-[(2-methoxyethyl)...)
Affinity DataIC50:  5.40nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285473(4-[4-Cyano-2-({[(2′R,4S)-6-(2-pyrimidinylcar...)
Affinity DataIC50:  5.40nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285494(4-[4-Cyano-2-({[(2′R,4S)-6-(1,3-oxazol-2-yl)...)
Affinity DataIC50:  5.70nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285490(4-[4-Cyano-2-({[(2′R,4S)-6-(6-methyl-3-pyrid...)
Affinity DataIC50:  5.70nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285513(4-[4-Cyano-2-({[(1S,2R)-3′,3′-dimethyl...)
Affinity DataIC50:  5.70nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285491(4-[4-Cyano-2-({[(2′R,4S)-6-(6-fluoro-3-pyrid...)
Affinity DataIC50:  6.10nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285510(4-{4-Cyano-2-[({(2′R,3S)-5-[(2-methoxyethyl)...)
Affinity DataIC50:  6.20nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285504(4-[4-Cyano-2-({[(2′R,4S)-7-(methylcarbamoyl)...)
Affinity DataIC50:  6.40nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285497(4-[4-Cyano-2-({[(2′R,4S)-6-(5-fluoro-2-pyrid...)
Affinity DataIC50:  6.70nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285505(4-{4-Cyano-2-[({(2′R,4S)-7-[(2-methoxyethyl)...)
Affinity DataIC50:  6.90nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285477(4-[4-Cyano-2-({[(2′R,4S)-6-(tetrahydro-2H-py...)
Affinity DataIC50:  7.20nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285509(4-[4-Cyano-2-({[(2′R,3S)-5-(methylcarbamoyl)...)
Affinity DataIC50:  7.20nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285467(4-[4-Cyano-2-({[(2′R,4S)-6-(isopropylcarbamo...)
Affinity DataIC50:  7.80nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285481(4-{4-Cyano-2-[({(2′R,4S)-6-[(2-ethoxyethyl)c...)
Affinity DataIC50:  8.30nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285507(4-{4-Cyano-2-[({(2′R,4S)-7-methoxy-6-[(2-met...)
Affinity DataIC50:  8.40nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285501(4-[4-Cyano-2-(({[(2′R,4S)-7-fluoro-6-(methyl...)
Affinity DataIC50:  8.5nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285488(4-[4-Cyano-2-({[(2′R,4S)-6-(2-oxo-1-pyrrolid...)
Affinity DataIC50:  8.60nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285503(4-[4-Cyano-2-({[(2′R,4S)-7-fluoro-6-(isoprop...)
Affinity DataIC50:  9.5nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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