BindingDB logo
myBDB logout

Patent code US10085986

Compile Data Set for Download or QSAR
Found 20 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
D-amino-acid oxidase


(Homo sapiens (human))
BDBM287759
PNG
(US10085986, Example 1)
Show SMILES Oc1cnc(SCc2cccc(Cl)c2)[nH]c1=O
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
UniChem
n/an/a 120n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...


US Patent US10085986 (2018)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (human))
BDBM287762
PNG
(US10085986, Example 5)
Show SMILES Oc1cnc(SCc2ccc3ccccc3c2)[nH]c1=O
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
UniChem
n/an/a 120n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...


US Patent US10085986 (2018)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (human))
BDBM287765
PNG
(US10085986, Example 10)
Show SMILES Oc1cnc(SCc2cccc(c2)C(F)(F)F)[nH]c1=O
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
UniChem
n/an/a 150n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...


US Patent US10085986 (2018)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (human))
BDBM287766
PNG
(US10085986, Example 11)
Show SMILES Oc1cnc(SCc2cc(F)cc(Cl)c2)[nH]c1=O
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
UniChem
n/an/a 150n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...


US Patent US10085986 (2018)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (human))
BDBM287764
PNG
(US10085986, Example 9)
Show SMILES COc1cccc(CSc2ncc(O)c(=O)[nH]2)c1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
UniChem
n/an/a 160n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...


US Patent US10085986 (2018)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (human))
BDBM287763
PNG
(US10085986, Example 6)
Show SMILES Oc1cnc(SCc2cccc(F)c2)[nH]c1=O
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
UniChem
n/an/a 170n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...


US Patent US10085986 (2018)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (human))
BDBM287770
PNG
(US10085986, Example 18)
Show SMILES Oc1cnc(SCc2cccc(OC(F)F)c2)[nH]c1=O
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
UniChem
n/an/a 190n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...


US Patent US10085986 (2018)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (human))
BDBM287761
PNG
(US10085986, Example 4)
Show SMILES Oc1cnc(SCc2ccc(Cl)cc2)[nH]c1=O
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
UniChem
n/an/a 220n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...


US Patent US10085986 (2018)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (human))
BDBM287760
PNG
(US10085986, Example 2)
Show SMILES Oc1cnc(SCc2ccccc2)[nH]c1=O
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
UniChem
n/an/a 230n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...


US Patent US10085986 (2018)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (human))
BDBM287771
PNG
(US10085986, Example 20)
Show SMILES Oc1cnc(SCc2cccnc2)[nH]c1=O
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
UniChem
n/an/a 470n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...


US Patent US10085986 (2018)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (human))
BDBM287767
PNG
(US10085986, Example 12)
Show SMILES Cc1nc(no1)-c1cccc(CSc2ncc(O)c(=O)[nH]2)c1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
UniChem
n/an/a 500n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...


US Patent US10085986 (2018)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (human))
BDBM287769
PNG
(US10085986, Example 16)
Show SMILES Oc1cnc(SCc2cccc3OCCOc23)[nH]c1=O
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
UniChem
n/an/a 540n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...


US Patent US10085986 (2018)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (human))
BDBM287773
PNG
(US10085986, Example 26)
Show SMILES Oc1cnc(SCc2ccc3nccn3c2)[nH]c1=O
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
UniChem
n/an/a 740n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...


US Patent US10085986 (2018)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (human))
BDBM287776
PNG
(US10085986, Example 33)
Show SMILES Oc1cnc(CCc2ccccc2)[nH]c1=O
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
UniChem
n/an/a 1.20E+3n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...


US Patent US10085986 (2018)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (human))
BDBM287768
PNG
(US10085986, Example 14)
Show SMILES CC(Sc1ncc(O)c(=O)[nH]1)c1ccccc1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
UniChem
n/an/a 1.20E+3n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...


US Patent US10085986 (2018)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (human))
BDBM287772
PNG
(US10085986, Example 21)
Show SMILES Cc1cc(CSc2ncc(O)c(=O)[nH]2)n(C)n1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
UniChem
n/an/a 1.60E+3n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...


US Patent US10085986 (2018)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (human))
BDBM287778
PNG
(US10085986, Example 35)
Show SMILES COc1ccc(CSc2ncc(O)c(=O)n2C)cc1
Show InChI InChI=1S/C13H14N2O3S/c1-15-12(17)11(16)7-14-13(15)19-8-9-3-5-10(18-2)6-4-9/h3-7,16H,8H2,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
UniChem
n/an/a 1.80E+3n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...


US Patent US10085986 (2018)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (human))
BDBM287777
PNG
(US10085986, Example 34)
Show SMILES Oc1c(nc(SCc2ccccc2)[nH]c1=O)C(F)(F)F
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
UniChem
n/an/a 2.70E+3n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...


US Patent US10085986 (2018)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (human))
BDBM287774
PNG
(US10085986, Example 30)
Show SMILES Oc1cnc(CSc2ccccc2)[nH]c1=O
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
UniChem
n/an/a 2.80E+3n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...


US Patent US10085986 (2018)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (human))
BDBM287775
PNG
(US10085986, Example 31)
Show SMILES Oc1cnc(COc2ccccc2)[nH]c1=O
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
UniChem
n/an/a 3.20E+3n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...


US Patent US10085986 (2018)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%