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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (Homo sapiens (Human)) | BDBM288386 (US10087187, Compound 81) | PDB UniProtKB/SwissProt GoogleScholar AffyNet  | UniChem | n/a | n/a | n/a | 2.69E+4 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (human)) | BDBM288386 (US10087187, Compound 81) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | 724 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase mTOR (Homo sapiens (human)) | BDBM288386 (US10087187, Compound 81) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | >3.02E+4 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (Homo sapiens (Human)) | BDBM288387 (US10087187, Compound 82) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | 3.24E+4 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase mTOR (Homo sapiens (human)) | BDBM288387 (US10087187, Compound 82) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | 2.51E+4 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (Homo sapiens (human)) | BDBM288388 (US10087187, Compound 83) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (human)) | BDBM288388 (US10087187, Compound 83) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | 309 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (human)) | BDBM288390 (US10087187, Compound 85) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | 75 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (Homo sapiens (Human)) | BDBM288391 (US10087187, Compound 86) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | 1.78E+3 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (human)) | BDBM288391 (US10087187, Compound 86) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | 1.32E+4 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (Homo sapiens (human)) | BDBM288393 (US10087187, Compound 88) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (Homo sapiens (Human)) | BDBM288396 (US10087187, Compound 93) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | >3.02E+4 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (human)) | BDBM288403 (US10087187, Compound 104) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | 1.51E+4 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (Homo sapiens (human)) | BDBM288406 (US10087187, Compound 107) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (human)) | BDBM288406 (US10087187, Compound 107) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | 8.71E+3 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (Homo sapiens (Human)) | BDBM288408 (US10087187, Compound 109) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | 1.28E+4 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (Homo sapiens (human)) | BDBM288408 (US10087187, Compound 109) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (human)) | BDBM288408 (US10087187, Compound 109) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | 98 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase mTOR (Homo sapiens (human)) | BDBM288328 (US10087187, Compound 18) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | >3.02E+4 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (Homo sapiens (Human)) | BDBM288329 (US10087187, Compound 19) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | 886 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (human)) | BDBM288328 (US10087187, Compound 18) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | >3.02E+4 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (human)) | BDBM288330 (US10087187, Compound 20) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | 4.79E+3 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (Homo sapiens (human)) | BDBM288331 (US10087187, Compound 21) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (human)) | BDBM288331 (US10087187, Compound 21) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (Homo sapiens (Human)) | BDBM50200972 (CHEMBL3974658 | US10087187, Compound 22) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | n/a | n/a | n/a | 1.59E+3 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase mTOR (Homo sapiens (human)) | BDBM288333 (US10087187, Compound 23) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | 2.06E+4 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (Homo sapiens (human)) | BDBM288335 (US10087187, Compound 25 | US10087187, Compound 27) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (Homo sapiens (human)) | BDBM288335 (US10087187, Compound 25 | US10087187, Compound 27) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (human)) | BDBM288338 (US10087187, Compound 28) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (human)) | BDBM288342 (US10087187, Compound 32) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (Homo sapiens (Human)) | BDBM288380 (US10087187, Compound 73) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | 3.24E+3 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (Homo sapiens (human)) | BDBM288380 (US10087187, Compound 73) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (human)) | BDBM288381 (US10087187, Compound 74 | US10087187, Compound 77 ...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (human)) | BDBM288381 (US10087187, Compound 74 | US10087187, Compound 77 ...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | 9.77E+3 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (human)) | BDBM288381 (US10087187, Compound 74 | US10087187, Compound 77 ...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | 8.32E+3 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (human)) | BDBM50200930 (CHEMBL3928423 | US10087187, Compound 66) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | n/a | n/a | n/a | 692 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (human)) | BDBM288377 (US10087187, Compound 68) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | 62 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (human)) | BDBM288351 (US10087187, Compound 41) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (Homo sapiens (Human)) | BDBM50200968 (CHEMBL3983623 | US10087187, Compound 46) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | n/a | n/a | n/a | 661 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (human)) | BDBM288356 (US10087187, Compound 47) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (Homo sapiens (Human)) | BDBM288358 (US10087187, Compound 49) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | 1.35E+4 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (Homo sapiens (human)) | BDBM288358 (US10087187, Compound 49) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase mTOR (Homo sapiens (human)) | BDBM288358 (US10087187, Compound 49) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | >3.02E+4 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (Homo sapiens (Human)) | BDBM288360 (US10087187, Compound 51) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (Homo sapiens (human)) | BDBM288360 (US10087187, Compound 51) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase mTOR (Homo sapiens (human)) | BDBM50200970 (CHEMBL3955003 | US10087187, Compound 52) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | n/a | n/a | n/a | 1.07E+4 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (human)) | BDBM288366 (US10087187, Compound 57) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | 891 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (Homo sapiens (human)) | BDBM50200978 (CHEMBL3956037 | US10087187, Compound 58) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | n/a | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase mTOR (Homo sapiens (human)) | BDBM50200978 (CHEMBL3956037 | US10087187, Compound 58) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | n/a | n/a | n/a | 2.14E+4 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (Homo sapiens (human)) | BDBM288368 (US10087187, Compound 59) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | n/a | |
Janssen Pharmaceutica NV US Patent | Assay Description Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa... | US Patent US10087187 (2018) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
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