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Patent code US10100016

Compile Data Set for Download or QSAR
Found 53 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290450
PNG
(2{[4-(4-Cyanonaphthalen)isoquinolin-6-yl]thio}-2-m...)
Show SMILES CC(C)(Sc1ccc2cncc(-c3ccc(C#N)c4ccccc34)c2c1)C(O)=O
Show InChI InChI=1S/C24H18N2O2S/c1-24(2,23(27)28)29-17-9-7-16-13-26-14-22(21(16)11-17)20-10-8-15(12-25)18-5-3-4-6-19(18)20/h3-11,13-14H,1-2H3,(H,27,28)
KEGG

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US Patent
n/an/a 8n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290480
PNG
(US10100016, Compound 45B)
Show SMILES C[C@@H](CC(O)=O)c1cc2cncc(-c3ccc(C#N)c4ccccc34)c2s1
Show InChI InChI=1S/C22H16N2O2S/c1-13(8-21(25)26)20-9-15-11-24-12-19(22(15)27-20)18-7-6-14(10-23)16-4-2-3-5-17(16)18/h2-7,9,11-13H,8H2,1H3,(H,25,26)/t13-/m0/s1
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n/an/a 10n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290470
PNG
(US10100016, Compound 43A)
Show SMILES C[C@H](CC(O)=O)c1cc2c(cncc2s1)-c1ccc(C#N)c2ccccc12
Show InChI InChI=1S/C22H16N2O2S/c1-13(8-22(25)26)20-9-18-19(11-24-12-21(18)27-20)17-7-6-14(10-23)15-4-2-3-5-16(15)17/h2-7,9,11-13H,8H2,1H3,(H,25,26)/t13-/m1/s1
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n/an/a 11n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290481
PNG
(3-[4-(4-Cyanonaphthalen-1-yl)isoquinolin-6-yl]-2,2...)
Show SMILES CC(C)(Cc1ccc2cncc(-c3ccc(C#N)c4ccccc34)c2c1)C(O)=O
Show InChI InChI=1S/C25H20N2O2/c1-25(2,24(28)29)12-16-7-8-18-14-27-15-23(22(18)11-16)21-10-9-17(13-26)19-5-3-4-6-20(19)21/h3-11,14-15H,12H2,1-2H3,(H,28,29)
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n/an/a 12n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290489
PNG
(3-[4-(4-Cyanophenyl)thieno[2,3-c]pyridin-2-yl]-2,2...)
Show SMILES CC(C)(Cc1cc2c(cncc2s1)-c1ccc(cc1)C#N)C(O)=O
Show InChI InChI=1S/C19H16N2O2S/c1-19(2,18(22)23)8-14-7-15-16(10-21-11-17(15)24-14)13-5-3-12(9-20)4-6-13/h3-7,10-11H,8H2,1-2H3,(H,22,23)
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n/an/a 12n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290448
PNG
(2{[4-(4-Cyanophenyl)isoquinolin-6-yl]thio-2-methyl...)
Show SMILES CC(C)(Sc1ccc2cncc(-c3ccc(cc3)C#N)c2c1)C(O)=O
Show InChI InChI=1S/C20H16N2O2S/c1-20(2,19(23)24)25-16-8-7-15-11-22-12-18(17(15)9-16)14-5-3-13(10-21)4-6-14/h3-9,11-12H,1-2H3,(H,23,24)
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n/an/a 15n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290479
PNG
(3-[4-(4-Cyanonaphthalen-1-yl)isoquinolin-6-yl]-2-m...)
Show SMILES CC(Cc1ccc2cncc(-c3ccc(C#N)c4ccccc34)c2c1)C(O)=O
Show InChI InChI=1S/C24H18N2O2/c1-15(24(27)28)10-16-6-7-18-13-26-14-23(22(18)11-16)21-9-8-17(12-25)19-4-2-3-5-20(19)21/h2-9,11,13-15H,10H2,1H3,(H,27,28)
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n/an/a 15n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290487
PNG
(3-[4-(4-Cyanonaphthalen-1-yl)thieno[2,3-c]pyridin-...)
Show SMILES CC(C)(Cc1cc2c(cncc2s1)-c1ccc(C#N)c2ccccc12)C(O)=O
Show InChI InChI=1S/C23H18N2O2S/c1-23(2,22(26)27)10-15-9-19-20(12-25-13-21(19)28-15)18-8-7-14(11-24)16-5-3-4-6-17(16)18/h3-9,12-13H,10H2,1-2H3,(H,26,27)
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n/an/a 18n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290490
PNG
(1-{[4-(4-cyanonaphthalen-1-yl)isoquinolin-6-yl]thi...)
Show SMILES OC(=O)C1(CCC1)Sc1ccc2cncc(-c3ccc(C#N)c4ccccc34)c2c1
Show InChI InChI=1S/C25H18N2O2S/c26-13-16-7-9-21(20-5-2-1-4-19(16)20)23-15-27-14-17-6-8-18(12-22(17)23)30-25(24(28)29)10-3-11-25/h1-2,4-9,12,14-15H,3,10-11H2,(H,28,29)
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n/an/a 18n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290488
PNG
(2-{[4-(2-Chloro-4-cyanophenyl)isoquinolin-6-yl]thi...)
Show SMILES CC(C)(Sc1ccc2cncc(-c3ccc(cc3Cl)C#N)c2c1)C(O)=O
Show InChI InChI=1S/C20H15ClN2O2S/c1-20(2,19(24)25)26-14-5-4-13-10-23-11-17(16(13)8-14)15-6-3-12(9-22)7-18(15)21/h3-8,10-11H,1-2H3,(H,24,25)
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n/an/a 18n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290467
PNG
(2{[4-(5-Cyanonaphthalen-1-yl)isoquinolin-6-yl]thio...)
Show SMILES CC(C)(Sc1ccc2cncc(-c3cccc4c(cccc34)C#N)c2c1)C(O)=O
Show InChI InChI=1S/C24H18N2O2S/c1-24(2,23(27)28)29-17-10-9-16-13-26-14-22(21(16)11-17)20-8-4-6-18-15(12-25)5-3-7-19(18)20/h3-11,13-14H,1-2H3,(H,27,28)
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n/an/a 19n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290515
PNG
(3-[4-(4-Cyanophenyl)isoquinolin-6-yl]-2,2-dimethyl...)
Show SMILES CC(C)(Cc1ccc2cncc(-c3ccc(cc3)C#N)c2c1)C(O)=O
Show InChI InChI=1S/C21H18N2O2/c1-21(2,20(24)25)10-15-5-8-17-12-23-13-19(18(17)9-15)16-6-3-14(11-22)4-7-16/h3-9,12-13H,10H2,1-2H3,(H,24,25)
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n/an/a 19n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290477
PNG
(3-[4-(4-Cyanonaphthalen-1-yl)isoquinolin-6-yl]buty...)
Show SMILES CC(CC(O)=O)c1ccc2cncc(-c3ccc(C#N)c4ccccc34)c2c1
Show InChI InChI=1S/C24H18N2O2/c1-15(10-24(27)28)16-6-7-18-13-26-14-23(22(18)11-16)21-9-8-17(12-25)19-4-2-3-5-20(19)21/h2-9,11,13-15H,10H2,1H3,(H,27,28)
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n/an/a 24n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290468
PNG
(3-[4-(4-Cyanonaphthalen-1-yl)thieno[2,3-c]pyridin-...)
Show SMILES CC(Cl)(CC(O)=O)c1cc2c(cncc2s1)-c1ccc(C#N)c2ccccc12
Show InChI InChI=1S/C22H15ClN2O2S/c1-22(23,9-21(26)27)20-8-17-18(11-25-12-19(17)28-20)16-7-6-13(10-24)14-4-2-3-5-15(14)16/h2-8,11-12H,9H2,1H3,(H,26,27)
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n/an/a 24n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290457
PNG
(3-[4-[(4-Cyanonaphthalen-1-yl)thieno[2,3-c]pyridin...)
Show SMILES OC(=O)CCc1cc2c(cncc2s1)-c1ccc(C#N)c2ccccc12
Show InChI InChI=1S/C21H14N2O2S/c22-10-13-5-7-17(16-4-2-1-3-15(13)16)19-11-23-12-20-18(19)9-14(26-20)6-8-21(24)25/h1-5,7,9,11-12H,6,8H2,(H,24,25)
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n/an/a 35n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290472
PNG
(US10100016, Compound 43B)
Show SMILES C[C@@H](CC(O)=O)c1cc2c(cncc2s1)-c1ccc(C#N)c2ccccc12
Show InChI InChI=1S/C22H16N2O2S/c1-13(8-22(25)26)20-9-18-19(11-24-12-21(18)27-20)17-7-6-14(10-23)15-4-2-3-5-16(15)17/h2-7,9,11-13H,8H2,1H3,(H,25,26)/t13-/m0/s1
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n/an/a 37n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290599
PNG
(3-[7-(4-Cyanonaphthalen-1-yl)thieno[3,2-c]pyridine...)
Show SMILES CC(CC(O)=O)c1cc2cncc(-c3ccc(C#N)c4ccccc34)c2s1
Show InChI InChI=1S/C22H16N2O2S/c1-13(8-21(25)26)20-9-15-11-24-12-19(22(15)27-20)18-7-6-14(10-23)16-4-2-3-5-17(16)18/h2-7,9,11-13H,8H2,1H3,(H,25,26)
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n/an/a 37n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290474
PNG
(US10100016, Compound 44A)
Show SMILES C[C@H](CC(O)=O)c1cc2cncc(-c3ccc(cc3)C#N)c2s1
Show InChI InChI=1S/C18H14N2O2S/c1-11(6-17(21)22)16-7-14-9-20-10-15(18(14)23-16)13-4-2-12(8-19)3-5-13/h2-5,7,9-11H,6H2,1H3,(H,21,22)/t11-/m1/s1
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n/an/a 38n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290447
PNG
(3-[7-(4-Cyanophenyl)thieno[3,2-c]pyridin-2-yl]-2,2...)
Show SMILES CC(C)(Cc1cc2cncc(-c3ccc(cc3)C#N)c2s1)C(O)=O
Show InChI InChI=1S/C19H16N2O2S/c1-19(2,18(22)23)8-15-7-14-10-21-11-16(17(14)24-15)13-5-3-12(9-20)4-6-13/h3-7,10-11H,8H2,1-2H3,(H,22,23)
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n/an/a 42n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290484
PNG
(US10100016, Compound 46B)
Show SMILES C[C@H](Cc1cc2cncc(-c3ccc(C#N)c4ccccc34)c2s1)C(O)=O
Show InChI InChI=1S/C22H16N2O2S/c1-13(22(25)26)8-16-9-15-11-24-12-20(21(15)27-16)19-7-6-14(10-23)17-4-2-3-5-18(17)19/h2-7,9,11-13H,8H2,1H3,(H,25,26)/t13-/m1/s1
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n/an/a 51n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290485
PNG
(2-{[4-(3-Chloro-4-cyanophenyl)isoquinolin-6-yl]thi...)
Show SMILES CC(C)(Sc1ccc2cncc(-c3ccc(C#N)c(Cl)c3)c2c1)C(O)=O
Show InChI InChI=1S/C20H15ClN2O2S/c1-20(2,19(24)25)26-15-6-5-14-10-23-11-17(16(14)8-15)12-3-4-13(9-22)18(21)7-12/h3-8,10-11H,1-2H3,(H,24,25)
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n/an/a 55n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290462
PNG
(2{[4-(4-Cyano-2-fluorophenyl)isoquinolin-6-yl]thio...)
Show SMILES CC(C)(Sc1ccc2cncc(-c3ccc(cc3F)C#N)c2c1)C(O)=O
Show InChI InChI=1S/C20H15FN2O2S/c1-20(2,19(24)25)26-14-5-4-13-10-23-11-17(16(13)8-14)15-6-3-12(9-22)7-18(15)21/h3-8,10-11H,1-2H3,(H,24,25)
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n/an/a 57n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290469
PNG
(2-{[4-(8-Cyano-2,3-dihydro-1,4-benzodioxan-5-yl)is...)
Show SMILES CC(C)(Sc1ccc2cncc(-c3ccc(C#N)c4OCCOc34)c2c1)C(O)=O
Show InChI InChI=1S/C22H18N2O4S/c1-22(2,21(25)26)29-15-5-3-14-11-24-12-18(17(14)9-15)16-6-4-13(10-23)19-20(16)28-8-7-27-19/h3-6,9,11-12H,7-8H2,1-2H3,(H,25,26)
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n/an/a 62n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290471
PNG
(2-{[4-(4-Cyano-7-fluoronaphthalen-1-yl)isoquinolin...)
Show SMILES CC(C)(Sc1ccc2cncc(-c3ccc(C#N)c4ccc(F)cc34)c2c1)C(O)=O
Show InChI InChI=1S/C24H17FN2O2S/c1-24(2,23(28)29)30-17-6-3-15-12-27-13-22(20(15)10-17)19-7-4-14(11-26)18-8-5-16(25)9-21(18)19/h3-10,12-13H,1-2H3,(H,28,29)
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n/an/a 71n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290439
PNG
(3-[7-(4-Cyanonaphthalen-1-yl)thieno[3,2-c]pyridin-...)
Show SMILES OC(=O)CCc1cc2cncc(-c3ccc(C#N)c4ccccc34)c2s1
Show InChI InChI=1S/C21H14N2O2S/c22-10-13-5-7-18(17-4-2-1-3-16(13)17)19-12-23-11-14-9-15(26-21(14)19)6-8-20(24)25/h1-5,7,9,11-12H,6,8H2,(H,24,25)
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n/an/a 87n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290483
PNG
(2-{[4-(4-Cyanonaphthalen-1-yl)isoquinolin-6-yl]thi...)
Show SMILES CC(Sc1ccc2cncc(-c3ccc(C#N)c4ccccc34)c2c1)C(O)=O
Show InChI InChI=1S/C23H16N2O2S/c1-14(23(26)27)28-17-8-6-16-12-25-13-22(21(16)10-17)20-9-7-15(11-24)18-4-2-3-5-19(18)20/h2-10,12-14H,1H3,(H,26,27)
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n/an/a 100n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290431
PNG
(CAS No.:1352792-74-5 | RDEA3170 | US10100016, Veri...)
Show SMILES CC(C)(Sc1ccncc1-c1ccc(C#N)c2ccccc12)C(O)=O
Show InChI InChI=1S/C20H16N2O2S/c1-20(2,19(23)24)25-18-9-10-22-12-17(18)16-8-7-13(11-21)14-5-3-4-6-15(14)16/h3-10,12H,1-2H3,(H,23,24)
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n/an/a 113n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290491
PNG
(2-[4-(4-Cyanonaphthalen-1-yl)isoquinolin-6-yl]-2-m...)
Show SMILES CC(C)(C(O)=O)c1ccc2cncc(-c3ccc(C#N)c4ccccc34)c2c1
Show InChI InChI=1S/C24H18N2O2/c1-24(2,23(27)28)17-9-7-16-13-26-14-22(21(16)11-17)20-10-8-15(12-25)18-5-3-4-6-19(18)20/h3-11,13-14H,1-2H3,(H,27,28)
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n/an/a 116n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290494
PNG
(2-({1-[(2,6-dichlorophenyl)methyl]-3-methyl-1H-ind...)
Show SMILES Cc1nn(Cc2c(Cl)cccc2Cl)c2cc(SC(C)(C)C(O)=O)ccc12
Show InChI InChI=1S/C19H18Cl2N2O2S/c1-11-13-8-7-12(26-19(2,3)18(24)25)9-17(13)23(22-11)10-14-15(20)5-4-6-16(14)21/h4-9H,10H2,1-3H3,(H,24,25)
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n/an/a 119n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290465
PNG
(2{[4-(4-Cyanonaphthalen-1-yl)-8-fluoroisoquinolin-...)
Show SMILES CC(C)(Sc1cc(F)c2cncc(-c3ccc(C#N)c4ccccc34)c2c1)C(O)=O
Show InChI InChI=1S/C24H17FN2O2S/c1-24(2,23(28)29)30-15-9-19-20(12-27-13-21(19)22(25)10-15)18-8-7-14(11-26)16-5-3-4-6-17(16)18/h3-10,12-13H,1-2H3,(H,28,29)
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n/an/a 127n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290449
PNG
(3-[7-(4-Cyanonaphthalen-1-yl)thieno[3,2-c]pyridin-...)
Show SMILES CC(C)(Cc1cc2cncc(-c3ccc(C#N)c4ccccc34)c2s1)C(O)=O
Show InChI InChI=1S/C23H18N2O2S/c1-23(2,22(26)27)10-16-9-15-12-25-13-20(21(15)28-16)19-8-7-14(11-24)17-5-3-4-6-18(17)19/h3-9,12-13H,10H2,1-2H3,(H,26,27)
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n/an/a 139n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290482
PNG
(US10100016, Compound 46A)
Show SMILES C[C@@H](Cc1cc2cncc(-c3ccc(C#N)c4ccccc34)c2s1)C(O)=O
Show InChI InChI=1S/C22H16N2O2S/c1-13(22(25)26)8-16-9-15-11-24-12-20(21(15)27-16)19-7-6-14(10-23)17-4-2-3-5-18(17)19/h2-7,9,11-13H,8H2,1H3,(H,25,26)/t13-/m0/s1
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n/an/a 148n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290444
PNG
(3-[4-(4-Cyanophenyl)isoquinolin-6-yl]propionic Aci...)
Show SMILES OC(=O)CCc1ccc2cncc(-c3ccc(cc3)C#N)c2c1
Show InChI InChI=1S/C19H14N2O2/c20-10-14-2-5-15(6-3-14)18-12-21-11-16-7-1-13(9-17(16)18)4-8-19(22)23/h1-3,5-7,9,11-12H,4,8H2,(H,22,23)
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n/an/a 161n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290473
PNG
(3-[4-(4-Cyanophenyl)isoquinolin-6-yl]butyric Acid ...)
Show SMILES C\C(=C/C(O)=O)c1ccc2cncc(-c3ccc(cc3)[N+]([O-])=O)c2c1
Show InChI InChI=1S/C19H14N2O4/c1-12(8-19(22)23)14-2-3-15-10-20-11-18(17(15)9-14)13-4-6-16(7-5-13)21(24)25/h2-11H,1H3,(H,22,23)/b12-8+
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n/an/a 189n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290461
PNG
(3-[4-(4-Cyanonaphthalen-1-yl)-1-benzothiophen-2-yl...)
Show SMILES CC(C)(Cc1cc2c(cccc2s1)-c1ccc(C#N)c2ccccc12)C(O)=O
Show InChI InChI=1S/C24H19NO2S/c1-24(2,23(26)27)13-16-12-21-19(8-5-9-22(21)28-16)20-11-10-15(14-25)17-6-3-4-7-18(17)20/h3-12H,13H2,1-2H3,(H,26,27)
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n/an/a 209n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290452
PNG
(2{[4-(4-Cyanophenyl)isoquinolin-6-yl]oxy}-2-methyl...)
Show SMILES CC(C)(Oc1ccc2cncc(-c3ccc(cc3)C#N)c2c1)C(O)=O
Show InChI InChI=1S/C20H16N2O3/c1-20(2,19(23)24)25-16-8-7-15-11-22-12-18(17(15)9-16)14-5-3-13(10-21)4-6-14/h3-9,11-12H,1-2H3,(H,23,24)
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n/an/a 214n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290492
PNG
(3-{3-[(2, 6-dichlorophenyl)methyl]-1-methylimidazo...)
Show SMILES CC(NC(=O)Cc1c(Cl)cccc1Cl)c1ccc(CCC(O)=O)cn1
Show InChI InChI=1S/C18H18Cl2N2O3/c1-11(16-7-5-12(10-21-16)6-8-18(24)25)22-17(23)9-13-14(19)3-2-4-15(13)20/h2-5,7,10-11H,6,8-9H2,1H3,(H,22,23)(H,24,25)
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n/an/a 289n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290446
PNG
(2-[4-(4-Cyanonaphthalen-1-yl)isoquinolin-6-yl]acet...)
Show SMILES OC(=O)Cc1ccc2cncc(-c3ccc(C#N)c4ccccc34)c2c1
Show InChI InChI=1S/C22H14N2O2/c23-11-15-7-8-19(18-4-2-1-3-17(15)18)21-13-24-12-16-6-5-14(9-20(16)21)10-22(25)26/h1-9,12-13H,10H2,(H,25,26)
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n/an/a 327n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290475
PNG
((2E)-3-[4-(4-Cyanonaphthalen-1-yl)isoquinolin-6-yl...)
Show SMILES OC(=O)\C=C\c1ccc2cncc(-c3ccc(C#N)c4ccccc34)c2c1
Show InChI InChI=1S/C23H14N2O2/c24-12-16-8-9-20(19-4-2-1-3-18(16)19)22-14-25-13-17-7-5-15(11-21(17)22)6-10-23(26)27/h1-11,13-14H,(H,26,27)/b10-6+
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n/an/a 385n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290455
PNG
(3-{4-[(2,6-Dichlorophenyl)methyl]-1-benzothiophene...)
Show SMILES OC(=O)CCc1cc2c(Cc3c(Cl)cccc3Cl)cccc2s1
Show InChI InChI=1S/C18H14Cl2O2S/c19-15-4-2-5-16(20)14(15)9-11-3-1-6-17-13(11)10-12(23-17)7-8-18(21)22/h1-6,10H,7-9H2,(H,21,22)
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n/an/a 542n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290478
PNG
(US10100016, Compound 45A)
Show SMILES C[C@H](CC(O)=O)c1cc2cncc(-c3ccc(C#N)c4ccccc34)c2s1
Show InChI InChI=1S/C22H16N2O2S/c1-13(8-21(25)26)20-9-15-11-24-12-19(22(15)27-20)18-7-6-14(10-23)16-4-2-3-5-17(16)18/h2-7,9,11-13H,8H2,1H3,(H,25,26)/t13-/m1/s1
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n/an/a 580n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290466
PNG
(3-[4-(4-Cyanonaphthalen-1-yl)thieno[2,3-c]pyridin-...)
Show SMILES CC(O)(CC(O)=O)c1cc2c(cncc2s1)-c1ccc(C#N)c2ccccc12
Show InChI InChI=1S/C22H16N2O3S/c1-22(27,9-21(25)26)20-8-17-18(11-24-12-19(17)28-20)16-7-6-13(10-23)14-4-2-3-5-15(14)16/h2-8,11-12,27H,9H2,1H3,(H,25,26)
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n/an/a 934n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290493
PNG
(2-{[4-(4-Cyanonaphthalen-1-yl)phthalazin-6-yl]thio...)
Show SMILES CC(C)(Sc1ccc2cnnc(-c3ccc(C#N)c4ccccc34)c2c1)C(O)=O
Show InChI InChI=1S/C23H17N3O2S/c1-23(2,22(27)28)29-16-9-7-15-13-25-26-21(20(15)11-16)19-10-8-14(12-24)17-5-3-4-6-18(17)19/h3-11,13H,1-2H3,(H,27,28)
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n/an/a 971n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290597
PNG
(2-{[5-(4-Cyanophenyl)imidazo[1,2-a]pyridin-6-yl]th...)
Show SMILES CC(C)(Sc1ccc2nccn2c1-c1ccc(cc1)C#N)C(O)=O
Show InChI InChI=1S/C18H15N3O2S/c1-18(2,17(22)23)24-14-7-8-15-20-9-10-21(15)16(14)13-5-3-12(11-19)4-6-13/h3-10H,1-2H3,(H,22,23)
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UniProtKB/SwissProt

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UniChem
US Patent
n/an/a 1.73E+3n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290476
PNG
(US10100016, Compound 44B)
Show SMILES C[C@@H](CC(O)=O)c1cc2cncc(-c3ccc(cc3)C#N)c2s1
Show InChI InChI=1S/C18H14N2O2S/c1-11(6-17(21)22)16-7-14-9-20-10-15(18(14)23-16)13-4-2-12(8-19)3-5-13/h2-5,7,9-11H,6H2,1H3,(H,21,22)/t11-/m0/s1
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UniProtKB/SwissProt

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UniChem
US Patent
n/an/a 1.86E+3n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290451
PNG
(3-{7-[(2,6-Dichlorophenyl)methyl]-1-benzothiophene...)
Show SMILES OC(=O)CCc1cc2cccc(Cc3c(Cl)cccc3Cl)c2s1
Show InChI InChI=1S/C18H14Cl2O2S/c19-15-5-2-6-16(20)14(15)10-12-4-1-3-11-9-13(23-18(11)12)7-8-17(21)22/h1-6,9H,7-8,10H2,(H,21,22)
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UniProtKB/SwissProt

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US Patent
n/an/a 2.41E+3n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290440
PNG
(4-(4-cyanophenyl)isoquinoline-6-carboxylic Acid |...)
Show SMILES OC(=O)c1ccc2cncc(-c3ccc(cc3)C#N)c2c1
Show InChI InChI=1S/C17H10N2O2/c18-8-11-1-3-12(4-2-11)16-10-19-9-14-6-5-13(17(20)21)7-15(14)16/h1-7,9-10H,(H,20,21)
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UniProtKB/SwissProt

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US Patent
n/an/a 2.53E+3n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290458
PNG
(US10100016, Compound 7B)
Show SMILES C[C@H](Oc1ccc2cncc(-c3ccc(cc3)C#N)c2c1)C(O)=O
Show InChI InChI=1S/C19H14N2O3/c1-12(19(22)23)24-16-7-6-15-10-21-11-18(17(15)8-16)14-4-2-13(9-20)3-5-14/h2-8,10-12H,1H3,(H,22,23)/t12-/m0/s1
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UniProtKB/SwissProt

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US Patent
n/an/a 2.69E+3n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290600
PNG
(7-(4-Cyanonaphthalen-1-yl)thieno[3,2-c]pyridin-2-f...)
Show SMILES OC(=O)c1cc2cncc(-c3ccc(C#N)c4ccccc34)c2s1
Show InChI InChI=1S/C19H10N2O2S/c20-8-11-5-6-15(14-4-2-1-3-13(11)14)16-10-21-9-12-7-17(19(22)23)24-18(12)16/h1-7,9-10H,(H,22,23)
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UniProtKB/SwissProt

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US Patent
n/an/a 2.86E+3n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290443
PNG
(2-[7-(4-Cyanonaphthalen-1-yl)thieno[3,2-c]pyridin-...)
Show SMILES OC(=O)Cc1cc2cncc(-c3ccc(C#N)c4ccccc34)c2s1
Show InChI InChI=1S/C20H12N2O2S/c21-9-12-5-6-17(16-4-2-1-3-15(12)16)18-11-22-10-13-7-14(8-19(23)24)25-20(13)18/h1-7,10-11H,8H2,(H,23,24)
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US Patent
n/an/a 3.42E+3n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290463
PNG
(3-{4-[(2,6-Dichlorophenyl)methyl]-1-benzothiophen-...)
Show SMILES CC(C)(Cc1cc2c(Cc3c(Cl)cccc3Cl)cccc2s1)C(O)=O
Show InChI InChI=1S/C20H18Cl2O2S/c1-20(2,19(23)24)11-13-10-14-12(5-3-8-18(14)25-13)9-15-16(21)6-4-7-17(15)22/h3-8,10H,9,11H2,1-2H3,(H,23,24)
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US Patent
n/an/a 3.47E+3n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290445
PNG
(2-[7-(4-Cyanophenyl)thieno[3,2-c]pyridin-2-yl]acet...)
Show SMILES OC(=O)Cc1cc2cncc(-c3ccc(cc3)C#N)c2s1
Show InChI InChI=1S/C16H10N2O2S/c17-7-10-1-3-11(4-2-10)14-9-18-8-12-5-13(6-15(19)20)21-16(12)14/h1-5,8-9H,6H2,(H,19,20)
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UniProtKB/SwissProt

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US Patent
n/an/a 5.41E+3n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM290456
PNG
(US10100016, Compound 7A)
Show SMILES C[C@@H](Oc1ccc2cncc(-c3ccc(cc3)C#N)c2c1)C(O)=O
Show InChI InChI=1S/C19H14N2O3/c1-12(19(22)23)24-16-7-6-15-10-21-11-18(17(15)8-16)14-4-2-13(9-20)3-5-14/h2-8,10-12H,1H3,(H,22,23)/t12-/m1/s1
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UniProtKB/SwissProt

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UniChem
US Patent
n/an/a 5.52E+3n/an/an/an/an/an/a



SHANGHAI YINGLI PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37 C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...


US Patent US10100016 (2018)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%