Compile Data Set for Download or QSAR
maximum 50k data
Found 7 Enz. Inhib. hit(s) with all data for entry = 810
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
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US Patent
LigandPNGBDBM292097(3-(5-Hydroxy-5,6,7,8-tetrahydroquinolin-2-yl)-2-ox...)
Affinity DataIC50: <100nMT: 2°CAssay Description:Compounds were tested for their ability to inhibit human Glycogen Synthase Kinase-3 beta (hGSK-3β) to phosphorylate biotin-YRRAAVPPSPSLSRHSSPHQ(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM292098(US10100048, Example 2.2)
Affinity DataIC50: <100nMT: 2°CAssay Description:Compounds were tested for their ability to inhibit human Glycogen Synthase Kinase-3 beta (hGSK-3β) to phosphorylate biotin-YRRAAVPPSPSLSRHSSPHQ(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM292099(2-Oxo-3-(5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl)...)
Affinity DataIC50: <100nMT: 2°CAssay Description:Compounds were tested for their ability to inhibit human Glycogen Synthase Kinase-3 beta (hGSK-3β) to phosphorylate biotin-YRRAAVPPSPSLSRHSSPHQ(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM292103(US10100048, Example 6)
Affinity DataIC50: <100nMT: 2°CAssay Description:Compounds were tested for their ability to inhibit human Glycogen Synthase Kinase-3 beta (hGSK-3β) to phosphorylate biotin-YRRAAVPPSPSLSRHSSPHQ(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM292101(2-Hydroxy-3-(8-hydroxy-5,6,7,8-tetrahydroquinolin-...)
Affinity DataIC50: <100nMT: 2°CAssay Description:Compounds were tested for their ability to inhibit human Glycogen Synthase Kinase-3 beta (hGSK-3β) to phosphorylate biotin-YRRAAVPPSPSLSRHSSPHQ(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM292102(3-(6,7-Dihydro-5H-pyrrolo[3,4-b]pyridin-2-yl)-2-ox...)
Affinity DataIC50: <100nMT: 2°CAssay Description:Compounds were tested for their ability to inhibit human Glycogen Synthase Kinase-3 beta (hGSK-3β) to phosphorylate biotin-YRRAAVPPSPSLSRHSSPHQ(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM292100(2-Hydroxy-3-(5-oxo-5,6,7,8-tetrahydroquinolin-2-yl...)
Affinity DataIC50: <100nMT: 2°CAssay Description:Compounds were tested for their ability to inhibit human Glycogen Synthase Kinase-3 beta (hGSK-3β) to phosphorylate biotin-YRRAAVPPSPSLSRHSSPHQ(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent