BindingDB logo
myBDB logout

Patent code US10106571

Compile Data Set for Download or QSAR
Found 23 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
RNA polymerase (NS5B)


(Hepatitis C virus (HCV))
BDBM294055
PNG
(US10106571, Example 13)
Show SMILES CC[C@H](C)OC(=O)[C@H](C)NP(=O)(OC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@@](F)(Cl)[C@@H]1O)Oc1ccccc1
Show InChI InChI=1S/C22H28ClFN3O9P/c1-4-13(2)34-19(30)14(3)26-37(32,36-15-8-6-5-7-9-15)33-12-16-18(29)22(23,24)20(35-16)27-11-10-17(28)25-21(27)31/h5-11,13-14,16,18,20,29H,4,12H2,1-3H3,(H,26,32)(H,25,28,31)/t13-,14-,16+,18+,20+,22+,37?/m0/s1
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 61n/an/an/an/a



MEDIVIR AB

US Patent


Assay Description
The assay utilizes the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist...


US Patent US10106571 (2018)

More data for this
Ligand-Target Pair
RNA polymerase (NS5B)


(Hepatitis C virus (HCV))
BDBM294065
PNG
(US10106571, Example 25)
Show SMILES COC[C@H](C)OC(=O)[C@H](C)NP(=O)(OC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@@](F)(Cl)[C@@H]1O)Oc1ccccc1
Show InChI InChI=1S/C22H28ClFN3O10P/c1-13(11-33-3)35-19(30)14(2)26-38(32,37-15-7-5-4-6-8-15)34-12-16-18(29)22(23,24)20(36-16)27-10-9-17(28)25-21(27)31/h4-10,13-14,16,18,20,29H,11-12H2,1-3H3,(H,26,32)(H,25,28,31)/t13-,14-,16+,18+,20+,22+,38?/m0/s1
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 100n/an/an/an/a



MEDIVIR AB

US Patent


Assay Description
The assay utilizes the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist...


US Patent US10106571 (2018)

More data for this
Ligand-Target Pair
RNA polymerase (NS5B)


(Hepatitis C virus (HCV))
BDBM294060
PNG
(US10106571, Example 20)
Show SMILES COC[C@@H](C)OC(=O)[C@H](C)NP(=O)(OC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@@](F)(Cl)[C@@H]1O)Oc1ccccc1
Show InChI InChI=1S/C22H28ClFN3O10P/c1-13(11-33-3)35-19(30)14(2)26-38(32,37-15-7-5-4-6-8-15)34-12-16-18(29)22(23,24)20(36-16)27-10-9-17(28)25-21(27)31/h4-10,13-14,16,18,20,29H,11-12H2,1-3H3,(H,26,32)(H,25,28,31)/t13-,14+,16-,18-,20-,22-,38?/m1/s1
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 65n/an/an/an/a



MEDIVIR AB

US Patent


Assay Description
The assay utilizes the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist...


US Patent US10106571 (2018)

More data for this
Ligand-Target Pair
RNA polymerase (NS5B)


(Hepatitis C virus (HCV))
BDBM294061
PNG
(US10106571, Example 21)
Show SMILES COCC(COC)OC(=O)[C@H](C)NP(=O)(OC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@@](F)(Cl)[C@@H]1O)Oc1ccccc1
Show InChI InChI=1S/C23H30ClFN3O11P/c1-14(20(31)37-16(11-34-2)12-35-3)27-40(33,39-15-7-5-4-6-8-15)36-13-17-19(30)23(24,25)21(38-17)28-10-9-18(29)26-22(28)32/h4-10,14,16-17,19,21,30H,11-13H2,1-3H3,(H,27,33)(H,26,29,32)/t14-,17+,19+,21+,23+,40?/m0/s1
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 210n/an/an/an/a



MEDIVIR AB

US Patent


Assay Description
The assay utilizes the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist...


US Patent US10106571 (2018)

More data for this
Ligand-Target Pair
RNA polymerase (NS5B)


(Hepatitis C virus (HCV))
BDBM294040
PNG
(US10106571, Example 1)
Show SMILES OC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@@](F)(Cl)[C@@H]1O
Show InChI InChI=1S/C9H10ClFN2O5/c10-9(11)6(16)4(3-14)18-7(9)13-2-1-5(15)12-8(13)17/h1-2,4,6-7,14,16H,3H2,(H,12,15,17)/t4-,6-,7-,9-/m1/s1
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>5.00E+4n/an/an/an/a



MEDIVIR AB

US Patent


Assay Description
The assay utilizes the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist...


US Patent US10106571 (2018)

More data for this
Ligand-Target Pair
RNA polymerase (NS5B)


(Hepatitis C virus (HCV))
BDBM294045
PNG
(US10106571, Example 2 | US10106571, Example 23)
Show SMILES CC(C)OC(=O)[C@H](C)NP(=O)(OC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@@](F)(Cl)[C@@H]1O)Oc1ccccc1
Show InChI InChI=1S/C21H26ClFN3O9P/c1-12(2)33-18(29)13(3)25-36(31,35-14-7-5-4-6-8-14)32-11-15-17(28)21(22,23)19(34-15)26-10-9-16(27)24-20(26)30/h4-10,12-13,15,17,19,28H,11H2,1-3H3,(H,25,31)(H,24,27,30)/t13-,15+,17+,19+,21+,36?/m0/s1
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 55n/an/an/an/a



MEDIVIR AB

US Patent


Assay Description
The assay utilizes the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist...


US Patent US10106571 (2018)

More data for this
Ligand-Target Pair
RNA polymerase (NS5B)


(Hepatitis C virus (HCV))
BDBM294049
PNG
(US10106571, Example 7)
Show SMILES CCC(CC)COC(=O)[C@H](C)NP(=O)(OC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@@](F)(Cl)[C@@H]1O)Oc1ccccc1
Show InChI InChI=1S/C24H32ClFN3O9P/c1-4-16(5-2)13-35-21(32)15(3)28-39(34,38-17-9-7-6-8-10-17)36-14-18-20(31)24(25,26)22(37-18)29-12-11-19(30)27-23(29)33/h6-12,15-16,18,20,22,31H,4-5,13-14H2,1-3H3,(H,28,34)(H,27,30,33)/t15-,18+,20+,22+,24+,39?/m0/s1
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 55n/an/an/an/a



MEDIVIR AB

US Patent


Assay Description
The assay utilizes the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist...


US Patent US10106571 (2018)

More data for this
Ligand-Target Pair
RNA polymerase (NS5B)


(Hepatitis C virus (HCV))
BDBM294054
PNG
(US10106571, Example 12)
Show SMILES CC(C)OC(=O)[C@H](C)NP(=O)(OC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@@](F)(Cl)[C@@H]1O)Oc1cccc(c1)C1CC1
Show InChI InChI=1S/C24H30ClFN3O9P/c1-13(2)36-21(32)14(3)28-39(34,38-17-6-4-5-16(11-17)15-7-8-15)35-12-18-20(31)24(25,26)22(37-18)29-10-9-19(30)27-23(29)33/h4-6,9-11,13-15,18,20,22,31H,7-8,12H2,1-3H3,(H,28,34)(H,27,30,33)/t14-,18+,20+,22+,24+,39?/m0/s1
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 180n/an/an/an/a



MEDIVIR AB

US Patent


Assay Description
The assay utilizes the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist...


US Patent US10106571 (2018)

More data for this
Ligand-Target Pair
RNA polymerase (NS5B)


(Hepatitis C virus (HCV))
BDBM294045
PNG
(US10106571, Example 2 | US10106571, Example 23)
Show SMILES CC(C)OC(=O)[C@H](C)NP(=O)(OC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@@](F)(Cl)[C@@H]1O)Oc1ccccc1
Show InChI InChI=1S/C21H26ClFN3O9P/c1-12(2)33-18(29)13(3)25-36(31,35-14-7-5-4-6-8-14)32-11-15-17(28)21(22,23)19(34-15)26-10-9-16(27)24-20(26)30/h4-10,12-13,15,17,19,28H,11H2,1-3H3,(H,25,31)(H,24,27,30)/t13-,15+,17+,19+,21+,36?/m0/s1
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 5.10E+3n/an/an/an/a



MEDIVIR AB

US Patent


Assay Description
The assay utilizes the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist...


US Patent US10106571 (2018)

More data for this
Ligand-Target Pair
RNA polymerase (NS5B)


(Hepatitis C virus (HCV))
BDBM294047
PNG
(US10106571, Example 5)
Show SMILES CC[C@@H](C)OC(=O)[C@H](C)NP(=O)(OC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@@](F)(Cl)[C@@H]1O)Oc1ccccc1
Show InChI InChI=1S/C22H28ClFN3O9P/c1-4-13(2)34-19(30)14(3)26-37(32,36-15-8-6-5-7-9-15)33-12-16-18(29)22(23,24)20(35-16)27-11-10-17(28)25-21(27)31/h5-11,13-14,16,18,20,29H,4,12H2,1-3H3,(H,26,32)(H,25,28,31)/t13-,14+,16-,18-,20-,22-,37?/m1/s1
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 43n/an/an/an/a



MEDIVIR AB

US Patent


Assay Description
The assay utilizes the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist...


US Patent US10106571 (2018)

More data for this
Ligand-Target Pair
RNA polymerase (NS5B)


(Hepatitis C virus (HCV))
BDBM294066
PNG
(US10106571, Example 26)
Show SMILES CC(C)OC(=O)[C@H](C)NP(=O)(OC[C@H]1O[C@@H](n2ccc(N)nc2=O)[C@@](F)(Cl)[C@@H]1O)Oc1ccccc1
Show InChI InChI=1S/C21H27ClFN4O8P/c1-12(2)33-18(29)13(3)26-36(31,35-14-7-5-4-6-8-14)32-11-15-17(28)21(22,23)19(34-15)27-10-9-16(24)25-20(27)30/h4-10,12-13,15,17,19,28H,11H2,1-3H3,(H,26,31)(H2,24,25,30)/t13-,15+,17+,19+,21+,36?/m0/s1
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 86n/an/an/an/a



MEDIVIR AB

US Patent


Assay Description
The assay utilizes the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist...


US Patent US10106571 (2018)

More data for this
Ligand-Target Pair
RNA polymerase (NS5B)


(Hepatitis C virus (HCV))
BDBM294062
PNG
(US10106571, Example 22)
Show SMILES CCC(CC)OC(=O)[C@H](C)NP(=O)(OC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@@](F)(Cl)[C@@H]1O)Oc1ccccc1
Show InChI InChI=1S/C23H30ClFN3O9P/c1-4-15(5-2)35-20(31)14(3)27-38(33,37-16-9-7-6-8-10-16)34-13-17-19(30)23(24,25)21(36-17)28-12-11-18(29)26-22(28)32/h6-12,14-15,17,19,21,30H,4-5,13H2,1-3H3,(H,27,33)(H,26,29,32)/t14-,17+,19+,21+,23+,38?/m0/s1
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 58n/an/an/an/a



MEDIVIR AB

US Patent


Assay Description
The assay utilizes the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist...


US Patent US10106571 (2018)

More data for this
Ligand-Target Pair
RNA polymerase (NS5B)


(Hepatitis C virus (HCV))
BDBM294048
PNG
(US10106571, Example 6)
Show SMILES CCOC(=O)[C@H](C)NP(=O)(OC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@@](F)(Cl)[C@@H]1O)Oc1ccccc1
Show InChI InChI=1S/C20H24ClFN3O9P/c1-3-31-17(28)12(2)24-35(30,34-13-7-5-4-6-8-13)32-11-14-16(27)20(21,22)18(33-14)25-10-9-15(26)23-19(25)29/h4-10,12,14,16,18,27H,3,11H2,1-2H3,(H,24,30)(H,23,26,29)/t12-,14+,16+,18+,20+,35?/m0/s1
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 79n/an/an/an/a



MEDIVIR AB

US Patent


Assay Description
The assay utilizes the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist...


US Patent US10106571 (2018)

More data for this
Ligand-Target Pair
RNA polymerase (NS5B)


(Hepatitis C virus (HCV))
BDBM294050
PNG
(US10106571, Example 8)
Show SMILES CCCCOC(=O)[C@H](C)NP(=O)(OC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@@](F)(Cl)[C@@H]1O)Oc1ccccc1
Show InChI InChI=1S/C22H28ClFN3O9P/c1-3-4-12-33-19(30)14(2)26-37(32,36-15-8-6-5-7-9-15)34-13-16-18(29)22(23,24)20(35-16)27-11-10-17(28)25-21(27)31/h5-11,14,16,18,20,29H,3-4,12-13H2,1-2H3,(H,26,32)(H,25,28,31)/t14-,16+,18+,20+,22+,37?/m0/s1
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 44n/an/an/an/a



MEDIVIR AB

US Patent


Assay Description
The assay utilizes the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist...


US Patent US10106571 (2018)

More data for this
Ligand-Target Pair
RNA polymerase (NS5B)


(Hepatitis C virus (HCV))
BDBM294046
PNG
(US10106571, Example 4)
Show SMILES C[C@H](NP(=O)(OC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@@](F)(Cl)[C@@H]1O)Oc1ccccc1)C(=O)OC1CCCCC1
Show InChI InChI=1S/C24H30ClFN3O9P/c1-15(21(32)36-16-8-4-2-5-9-16)28-39(34,38-17-10-6-3-7-11-17)35-14-18-20(31)24(25,26)22(37-18)29-13-12-19(30)27-23(29)33/h3,6-7,10-13,15-16,18,20,22,31H,2,4-5,8-9,14H2,1H3,(H,28,34)(H,27,30,33)/t15-,18+,20+,22+,24+,39?/m0/s1
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 90n/an/an/an/a



MEDIVIR AB

US Patent


Assay Description
The assay utilizes the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist...


US Patent US10106571 (2018)

More data for this
Ligand-Target Pair
RNA polymerase (NS5B)


(Hepatitis C virus (HCV))
BDBM294051
PNG
(US10106571, Example 9)
Show SMILES CC(C)OC(=O)[C@H](C)NP(=O)(OC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@@](F)(Cl)[C@@H]1O)Oc1ccc2OCOc2c1
Show InChI InChI=1S/C22H26ClFN3O11P/c1-11(2)36-19(30)12(3)26-39(32,38-13-4-5-14-15(8-13)34-10-33-14)35-9-16-18(29)22(23,24)20(37-16)27-7-6-17(28)25-21(27)31/h4-8,11-12,16,18,20,29H,9-10H2,1-3H3,(H,26,32)(H,25,28,31)/t12-,16+,18+,20+,22+,39?/m0/s1
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 190n/an/an/an/a



MEDIVIR AB

US Patent


Assay Description
The assay utilizes the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist...


US Patent US10106571 (2018)

More data for this
Ligand-Target Pair
RNA polymerase (NS5B)


(Hepatitis C virus (HCV))
BDBM294053
PNG
(US10106571, Example 11)
Show SMILES COc1ccc(OP(=O)(N[C@@H](C)C(=O)OC(C)C)OC[C@H]2O[C@@H](n3ccc(=O)[nH]c3=O)[C@@](F)(Cl)[C@@H]2O)cc1
Show InChI InChI=1S/C22H28ClFN3O10P/c1-12(2)35-19(30)13(3)26-38(32,37-15-7-5-14(33-4)6-8-15)34-11-16-18(29)22(23,24)20(36-16)27-10-9-17(28)25-21(27)31/h5-10,12-13,16,18,20,29H,11H2,1-4H3,(H,26,32)(H,25,28,31)/t13-,16+,18+,20+,22+,38?/m0/s1
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 150n/an/an/an/a



MEDIVIR AB

US Patent


Assay Description
The assay utilizes the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist...


US Patent US10106571 (2018)

More data for this
Ligand-Target Pair
RNA polymerase (NS5B)


(Hepatitis C virus (HCV))
BDBM294058
PNG
(US10106571, Example 16)
Show SMILES CC(C)OC(=O)[C@H](C)NP(=O)(OC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@@](F)(Cl)[C@@H]1O)Oc1cccc(c1)C1(C)CC1
Show InChI InChI=1S/C25H32ClFN3O9P/c1-14(2)37-21(33)15(3)29-40(35,39-17-7-5-6-16(12-17)24(4)9-10-24)36-13-18-20(32)25(26,27)22(38-18)30-11-8-19(31)28-23(30)34/h5-8,11-12,14-15,18,20,22,32H,9-10,13H2,1-4H3,(H,29,35)(H,28,31,34)/t15-,18+,20+,22+,25+,40?/m0/s1
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 91n/an/an/an/a



MEDIVIR AB

US Patent


Assay Description
The assay utilizes the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist...


US Patent US10106571 (2018)

More data for this
Ligand-Target Pair
RNA polymerase (NS5B)


(Hepatitis C virus (HCV))
BDBM294064
PNG
(US10106571, Example 24)
Show SMILES CC(C)OC(=O)[C@H](C)NP(=O)(OC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@@](F)(Cl)[C@@H]1O)Oc1cccc2ncccc12
Show InChI InChI=1S/C24H27ClFN4O9P/c1-13(2)37-21(33)14(3)29-40(35,39-17-8-4-7-16-15(17)6-5-10-27-16)36-12-18-20(32)24(25,26)22(38-18)30-11-9-19(31)28-23(30)34/h4-11,13-14,18,20,22,32H,12H2,1-3H3,(H,29,35)(H,28,31,34)/t14-,18+,20+,22+,24+,40?/m0/s1
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 1.40E+3n/an/an/an/a



MEDIVIR AB

US Patent


Assay Description
The assay utilizes the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist...


US Patent US10106571 (2018)

More data for this
Ligand-Target Pair
RNA polymerase (NS5B)


(Hepatitis C virus (HCV))
BDBM294057
PNG
(US10106571, Example 15)
Show SMILES CC(C)OC(=O)[C@H](C)NP(=O)(OC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@@](F)(Cl)[C@@H]1O)Oc1cccc(c1)C1CCC1
Show InChI InChI=1S/C25H32ClFN3O9P/c1-14(2)37-22(33)15(3)29-40(35,39-18-9-5-8-17(12-18)16-6-4-7-16)36-13-19-21(32)25(26,27)23(38-19)30-11-10-20(31)28-24(30)34/h5,8-12,14-16,19,21,23,32H,4,6-7,13H2,1-3H3,(H,29,35)(H,28,31,34)/t15-,19+,21+,23+,25+,40?/m0/s1
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 90n/an/an/an/a



MEDIVIR AB

US Patent


Assay Description
The assay utilizes the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist...


US Patent US10106571 (2018)

More data for this
Ligand-Target Pair
RNA polymerase (NS5B)


(Hepatitis C virus (HCV))
BDBM294059
PNG
(US10106571, Example 17)
Show SMILES CC(C)OC(=O)[C@H](C)NP(=O)(OC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@@](F)(Cl)[C@@H]1O)Oc1ccc(cc1)C1(C)CC1
Show InChI InChI=1S/C25H32ClFN3O9P/c1-14(2)37-21(33)15(3)29-40(35,39-17-7-5-16(6-8-17)24(4)10-11-24)36-13-18-20(32)25(26,27)22(38-18)30-12-9-19(31)28-23(30)34/h5-9,12,14-15,18,20,22,32H,10-11,13H2,1-4H3,(H,29,35)(H,28,31,34)/t15-,18+,20+,22+,25+,40?/m0/s1
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 110n/an/an/an/a



MEDIVIR AB

US Patent


Assay Description
The assay utilizes the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist...


US Patent US10106571 (2018)

More data for this
Ligand-Target Pair
RNA polymerase (NS5B)


(Hepatitis C virus (HCV))
BDBM294052
PNG
(US10106571, Example 10)
Show SMILES COc1ccccc1OP(=O)(N[C@@H](C)C(=O)OC(C)C)OC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@@](F)(Cl)[C@@H]1O
Show InChI InChI=1S/C22H28ClFN3O10P/c1-12(2)35-19(30)13(3)26-38(32,37-15-8-6-5-7-14(15)33-4)34-11-16-18(29)22(23,24)20(36-16)27-10-9-17(28)25-21(27)31/h5-10,12-13,16,18,20,29H,11H2,1-4H3,(H,26,32)(H,25,28,31)/t13-,16+,18+,20+,22+,38?/m0/s1
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 45n/an/an/an/a



MEDIVIR AB

US Patent


Assay Description
The assay utilizes the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist...


US Patent US10106571 (2018)

More data for this
Ligand-Target Pair
RNA polymerase (NS5B)


(Hepatitis C virus (HCV))
BDBM294056
PNG
(US10106571, Example 14)
Show SMILES CCCOC(=O)[C@H](C)NP(=O)(OC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@@](F)(Cl)[C@@H]1O)Oc1ccccc1
Show InChI InChI=1S/C21H26ClFN3O9P/c1-3-11-32-18(29)13(2)25-36(31,35-14-7-5-4-6-8-14)33-12-15-17(28)21(22,23)19(34-15)26-10-9-16(27)24-20(26)30/h4-10,13,15,17,19,28H,3,11-12H2,1-2H3,(H,25,31)(H,24,27,30)/t13-,15+,17+,19+,21+,36?/m0/s1
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 76n/an/an/an/a



MEDIVIR AB

US Patent


Assay Description
The assay utilizes the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist...


US Patent US10106571 (2018)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%