Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with all data for entry = 1027
TargetBile acid receptor(Homo sapiens (Human))
Enanta Pharmaceuticals

US Patent
LigandPNGBDBM21674((4R)-4-[(1S,2S,5R,7S,9R,10R,11S,14R,15R)-5,9-dihyd...)
Affinity DataEC50: >1.00E+3nMAssay Description:Determination of a ligand mediated Gal4 promoter driven transactivation to quantify ligand binding mediated activation of FXR. FXR Reporter Assay kit...More data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Enanta Pharmaceuticals

US Patent
LigandPNGBDBM303498(US10138228, Example 3)
Affinity DataEC50: <100nMAssay Description:Determination of a ligand mediated Gal4 promoter driven transactivation to quantify ligand binding mediated activation of FXR. FXR Reporter Assay kit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Enanta Pharmaceuticals

US Patent
LigandPNGBDBM303497(US10138228, Example 2)
Affinity DataEC50:  5.50E+3nMAssay Description:Determination of a ligand mediated Gal4 promoter driven transactivation to quantify ligand binding mediated activation of FXR. FXR Reporter Assay kit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Enanta Pharmaceuticals

US Patent
LigandPNGBDBM303496(US10138228, Example 1)
Affinity DataEC50:  550nMAssay Description:Determination of a ligand mediated Gal4 promoter driven transactivation to quantify ligand binding mediated activation of FXR. FXR Reporter Assay kit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent