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Patent code US10149840

Compile Data Set for Download or QSAR
Found 3 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
POU domain, class 5, transcription factor 1


(Homo sapiens (human))
BDBM306793
PNG
(US10149840, Compound SR-4277 | US10149840, Series ...)
Show SMILES CC1=CC2=NC(CN2C=C1)C(=O)NCCSCc1ccccc1F
Show InChI InChI=1S/C18H20FN3OS/c1-13-6-8-22-11-16(21-17(22)10-13)18(23)20-7-9-24-12-14-4-2-3-5-15(14)19/h2-6,8,10,16H,7,9,11-12H2,1H3,(H,20,23)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 8.20E+3n/an/an/an/an/an/a



SHIN NIPPON BIOMEDICAL LABORATORIES, LTD.

US Patent


Assay Description
An existing amount of the OCT3 protein can be estimated from an amount of a compound free in the extracellular fluid in a method similar to a method ...


US Patent US10149840 (2018)

More data for this
Ligand-Target Pair
POU domain, class 5, transcription factor 1


(Homo sapiens (human))
BDBM306794
PNG
(US10149840, Compound SR-4229 | US10149840, Series ...)
Show SMILES CCOc1ccccc1-n1nnnc1SCc1cn2cc(C)ccc2n1
Show InChI InChI=1S/C18H18N6OS/c1-3-25-16-7-5-4-6-15(16)24-18(20-21-22-24)26-12-14-11-23-10-13(2)8-9-17(23)19-14/h4-11H,3,12H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.53E+4n/an/an/an/an/an/a



SHIN NIPPON BIOMEDICAL LABORATORIES, LTD.

US Patent


Assay Description
An existing amount of the OCT3 protein can be estimated from an amount of a compound free in the extracellular fluid in a method similar to a method ...


US Patent US10149840 (2018)

More data for this
Ligand-Target Pair
POU domain, class 5, transcription factor 1


(Homo sapiens (human))
BDBM50103514
PNG
(CHEBI:4975 | FAMOTIDINE | Famotidine | Fluxid | MK...)
Show SMILES NC(=N)Nc1nc(CSCCC(=N)NS(N)(=O)=O)cs1
Show InChI InChI=1S/C8H15N7O2S3/c9-6(15-20(12,16)17)1-2-18-3-5-4-19-8(13-5)14-7(10)11/h4H,1-3H2,(H2,9,15)(H2,12,16,17)(H4,10,11,13,14)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents

US Patent
n/an/a 6.76E+4n/an/an/an/an/an/a



SHIN NIPPON BIOMEDICAL LABORATORIES, LTD.

US Patent


Assay Description
An existing amount of the OCT3 protein can be estimated from an amount of a compound free in the extracellular fluid in a method similar to a method ...


US Patent US10149840 (2018)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%