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Found 10 Enz. Inhib. hit(s) with all data for entry = 1389
TargetCoagulation factor XI(Homo sapiens (Human))
Sichuan Haisco Pharmaceutical

US Patent
LigandPNGBDBM320260(US10174020, Compound 8-1)
Affinity DataKi:  2nMAssay Description:The following method was used to test the in vitro inhibitory effect of the compounds of the present invention on the activity of human blood-coagula...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Sichuan Haisco Pharmaceutical

US Patent
LigandPNGBDBM320262(5-[[2-[4-[5-chloro-2-(tetrazol-1-yl)phenyl]-2-oxo-...)
Affinity DataKi:  4nMAssay Description:The following method was used to test the in vitro inhibitory effect of the compounds of the present invention on the activity of human blood-coagula...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Sichuan Haisco Pharmaceutical

US Patent
LigandPNGBDBM320255(N-(2-carboxyindol-5-yl)-7-(5-chloro-2-(1H-tetrazol...)
Affinity DataKi:  9nMAssay Description:The following method was used to test the in vitro inhibitory effect of the compounds of the present invention on the activity of human blood-coagula...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Sichuan Haisco Pharmaceutical

US Patent
LigandPNGBDBM320258(N-(2-carboxyindol-5-yl)-2-(4-(5-chloro-2-(1H-tetra...)
Affinity DataKi:  14nMAssay Description:The following method was used to test the in vitro inhibitory effect of the compounds of the present invention on the activity of human blood-coagula...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Sichuan Haisco Pharmaceutical

US Patent
LigandPNGBDBM320256(N-(2-carboxyindol-5-yl)-2-(5-chloro-2-(1H-tetrazol...)
Affinity DataKi:  17nMAssay Description:The following method was used to test the in vitro inhibitory effect of the compounds of the present invention on the activity of human blood-coagula...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Sichuan Haisco Pharmaceutical

US Patent
LigandPNGBDBM320254(N-(4-carboxyphenyl)-7-(5-chloro-2-(H-tetrazol-1-yl...)
Affinity DataKi:  68nMAssay Description:The following method was used to test the in vitro inhibitory effect of the compounds of the present invention on the activity of human blood-coagula...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Sichuan Haisco Pharmaceutical

US Patent
LigandPNGBDBM320257(N-(4-carboxyphenyl)-2-(4-(5-chloro-2-(1H-tetrazol-...)
Affinity DataKi:  146nMAssay Description:The following method was used to test the in vitro inhibitory effect of the compounds of the present invention on the activity of human blood-coagula...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Sichuan Haisco Pharmaceutical

US Patent
LigandPNGBDBM320038(N-(4-carboxyphenyl)-2-(5-chloro-2-(1H-tetrazol-1-y...)
Affinity DataKi:  249nMAssay Description:The following method was used to test the in vitro inhibitory effect of the compounds of the present invention on the activity of human blood-coagula...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Sichuan Haisco Pharmaceutical

US Patent
LigandPNGBDBM320259(N-(4-methoxycarboxylaminophenyl)-7-(5-chloro-2-(1H...)
Affinity DataKi:  344nMAssay Description:The following method was used to test the in vitro inhibitory effect of the compounds of the present invention on the activity of human blood-coagula...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Sichuan Haisco Pharmaceutical

US Patent
LigandPNGBDBM320261(US10174020, Compound 8-2)
Affinity DataKi:  1.03E+3nMAssay Description:The following method was used to test the in vitro inhibitory effect of the compounds of the present invention on the activity of human blood-coagula...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent