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Patent code US10179761

Compile Data Set for Download or QSAR
Found 52 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sigma non-opioid intracellular receptor 1


(HUMAN)
BDBM321276
PNG
(N-[3-(benzylmethylamino)propyl]-3,4-dichlorobenzam...)
Show SMILES CN(CCCNC(=O)c1ccc(Cl)c(Cl)c1)Cc1ccccc1
Show InChI InChI=1S/C18H20Cl2N2O/c1-22(13-14-6-3-2-4-7-14)11-5-10-21-18(23)15-8-9-16(19)17(20)12-15/h2-4,6-9,12H,5,10-11,13H2,1H3,(H,21,23)
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1.10n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(HUMAN)
BDBM321285
PNG
(N-(2-(benzyl(methyl)amino)ethyl)-4-cyanobenzamide ...)
Show SMILES CN(CCNC(=O)c1ccc(cc1)C#N)Cc1ccccc1
Show InChI InChI=1S/C18H19N3O/c1-21(14-16-5-3-2-4-6-16)12-11-20-18(22)17-9-7-15(13-19)8-10-17/h2-10H,11-12,14H2,1H3,(H,20,22)
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1.20n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(HUMAN)
BDBM321275
PNG
(N-[3-(benzylmethylamino)propyl]-2,4-dichlorobenzam...)
Show SMILES CN(CCCNC(=O)c1ccc(Cl)cc1Cl)Cc1ccccc1
Show InChI InChI=1S/C18H20Cl2N2O/c1-22(13-14-6-3-2-4-7-14)11-5-10-21-18(23)16-9-8-15(19)12-17(16)20/h2-4,6-9,12H,5,10-11,13H2,1H3,(H,21,23)
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1.30n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(HUMAN)
BDBM321262
PNG
(N-[3-(benzylmethylamino)propyl]-4-trifluoromethylb...)
Show SMILES CN(CCCNC(=O)c1ccc(cc1)C(F)(F)F)Cc1ccccc1
Show InChI InChI=1S/C19H21F3N2O/c1-24(14-15-6-3-2-4-7-15)13-5-12-23-18(25)16-8-10-17(11-9-16)19(20,21)22/h2-4,6-11H,5,12-14H2,1H3,(H,23,25)
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1.40n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(HUMAN)
BDBM321261
PNG
(N-[3-(benzylmethylamino)propyl]-4-tertbutylbenzami...)
Show SMILES CN(CCCNC(=O)c1ccc(cc1)C(C)(C)C)Cc1ccccc1
Show InChI InChI=1S/C22H30N2O/c1-22(2,3)20-13-11-19(12-14-20)21(25)23-15-8-16-24(4)17-18-9-6-5-7-10-18/h5-7,9-14H,8,15-17H2,1-4H3,(H,23,25)
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1.60n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(HUMAN)
BDBM321268
PNG
(N-[4-(benzylmethylamino)butyl]-4-chlorobenzamide |...)
Show SMILES CN(CCCCNC(=O)c1ccc(Cl)cc1)Cc1ccccc1
Show InChI InChI=1S/C19H23ClN2O/c1-22(15-16-7-3-2-4-8-16)14-6-5-13-21-19(23)17-9-11-18(20)12-10-17/h2-4,7-12H,5-6,13-15H2,1H3,(H,21,23)
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1.70n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(HUMAN)
BDBM321281
PNG
(N-[3-(benzylmethylamino)propyl]-3-dimethylaminoben...)
Show SMILES CN(CCCNC(=O)c1cccc(c1)N(C)C)Cc1ccccc1
Show InChI InChI=1S/C20H27N3O/c1-22(2)19-12-7-11-18(15-19)20(24)21-13-8-14-23(3)16-17-9-5-4-6-10-17/h4-7,9-12,15H,8,13-14,16H2,1-3H3,(H,21,24)
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1.90n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(HUMAN)
BDBM321273
PNG
(N-[3-(benzylmethylamino)propyl]-4-bromobenzamide |...)
Show SMILES CN(CCCNC(=O)c1ccc(Br)cc1)Cc1ccccc1
Show InChI InChI=1S/C18H21BrN2O/c1-21(14-15-6-3-2-4-7-15)13-5-12-20-18(22)16-8-10-17(19)11-9-16/h2-4,6-11H,5,12-14H2,1H3,(H,20,22)
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2.10n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(HUMAN)
BDBM321278
PNG
(N-[3-(benzylmethylamino)propyl]-4-bromo-2-fluorobe...)
Show SMILES CN(CCCNC(=O)c1ccc(Br)cc1F)Cc1ccccc1
Show InChI InChI=1S/C18H20BrFN2O/c1-22(13-14-6-3-2-4-7-14)11-5-10-21-18(23)16-9-8-15(19)12-17(16)20/h2-4,6-9,12H,5,10-11,13H2,1H3,(H,21,23)
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2.90n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(HUMAN)
BDBM321267
PNG
(N-[3-(benzylmethylamino)propyl]-4-chlorobenzamide ...)
Show SMILES CN(CCCNC(=O)c1ccc(Cl)cc1)Cc1ccccc1
Show InChI InChI=1S/C18H21ClN2O/c1-21(14-15-6-3-2-4-7-15)13-5-12-20-18(22)16-8-10-17(19)11-9-16/h2-4,6-11H,5,12-14H2,1H3,(H,20,22)
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3.20n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(HUMAN)
BDBM321266
PNG
(N-[3-(2-(N-methylbenzyl)amino)ethyl]-4-chlorobenza...)
Show SMILES CNc1ccccc1CNCCCNC(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C18H22ClN3O/c1-20-17-6-3-2-5-15(17)13-21-11-4-12-22-18(23)14-7-9-16(19)10-8-14/h2-3,5-10,20-21H,4,11-13H2,1H3,(H,22,23)
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3.60n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(HUMAN)
BDBM321286
PNG
(N-(2-(benzyl(methyl)amino)ethyl)-4-nitrobenzamide ...)
Show SMILES CN(CCNC(=O)c1ccc(cc1)[N+]([O-])=O)Cc1ccccc1
Show InChI InChI=1S/C17H19N3O3/c1-19(13-14-5-3-2-4-6-14)12-11-18-17(21)15-7-9-16(10-8-15)20(22)23/h2-10H,11-13H2,1H3,(H,18,21)
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3.60n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(HUMAN)
BDBM321259
PNG
(N-[3-(benzylmethylamino)propyl]-4-propylbenzamide ...)
Show SMILES CCCc1ccc(cc1)C(=O)NCCCN(C)Cc1ccccc1
Show InChI InChI=1S/C21H28N2O/c1-3-8-18-11-13-20(14-12-18)21(24)22-15-7-16-23(2)17-19-9-5-4-6-10-19/h4-6,9-14H,3,7-8,15-17H2,1-2H3,(H,22,24)
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3.70n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(HUMAN)
BDBM321272
PNG
(N-[3-(benzylmethylamino)propyl]-3-bromobenzamide |...)
Show SMILES CN(CCCNC(=O)c1cccc(Br)c1)Cc1ccccc1
Show InChI InChI=1S/C18H21BrN2O/c1-21(14-15-7-3-2-4-8-15)12-6-11-20-18(22)16-9-5-10-17(19)13-16/h2-5,7-10,13H,6,11-12,14H2,1H3,(H,20,22)
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3.90n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(HUMAN)
BDBM321283
PNG
(N-[3-(benzylmethylamino)propyl]-4-nitrobenzamide |...)
Show SMILES CN(CCCNC(=O)c1ccc(cc1)[N+]([O-])=O)Cc1ccccc1
Show InChI InChI=1S/C18H21N3O3/c1-20(14-15-6-3-2-4-7-15)13-5-12-19-18(22)16-8-10-17(11-9-16)21(23)24/h2-4,6-11H,5,12-14H2,1H3,(H,19,22)
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4.30n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(HUMAN)
BDBM321269
PNG
(N-[3-(N-methyl-2-phenylethylamino)propyl]-4-chloro...)
Show SMILES CN(CCCNC(=O)c1ccc(Cl)cc1)CCc1ccccc1
Show InChI InChI=1S/C19H23ClN2O/c1-22(15-12-16-6-3-2-4-7-16)14-5-13-21-19(23)17-8-10-18(20)11-9-17/h2-4,6-11H,5,12-15H2,1H3,(H,21,23)
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4.30n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(HUMAN)
BDBM321284
PNG
(N-(2-(benzyl(methyl)amino)ethyl)-2,4-dichlorobenza...)
Show SMILES CN(CCNC(=O)c1ccc(Cl)cc1Cl)Cc1ccccc1
Show InChI InChI=1S/C17H18Cl2N2O/c1-21(12-13-5-3-2-4-6-13)10-9-20-17(22)15-8-7-14(18)11-16(15)19/h2-8,11H,9-10,12H2,1H3,(H,20,22)
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6.5n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(HUMAN)
BDBM321260
PNG
(N-[3-(benzylmethylamino)propyl]-4-butylbenzamide |...)
Show SMILES CCCCc1ccc(cc1)C(=O)NCCCN(C)Cc1ccccc1
Show InChI InChI=1S/C22H30N2O/c1-3-4-9-19-12-14-21(15-13-19)22(25)23-16-8-17-24(2)18-20-10-6-5-7-11-20/h5-7,10-15H,3-4,8-9,16-18H2,1-2H3,(H,23,25)
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7.30n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(HUMAN)
BDBM321274
PNG
(N-[3-(benzylmethylamino)propyl]-2,3-dichlorobenzam...)
Show SMILES CN(CCCNC(=O)c1cccc(Cl)c1Cl)Cc1ccccc1
Show InChI InChI=1S/C18H20Cl2N2O/c1-22(13-14-7-3-2-4-8-14)12-6-11-21-18(23)15-9-5-10-16(19)17(15)20/h2-5,7-10H,6,11-13H2,1H3,(H,21,23)
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10n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(HUMAN)
BDBM321265
PNG
(N-[3-(benzylmethylamino)propyl]-3-chlorobenzamide ...)
Show SMILES CN(CCCNC(=O)c1cccc(Cl)c1)Cc1ccccc1
Show InChI InChI=1S/C18H21ClN2O/c1-21(14-15-7-3-2-4-8-15)12-6-11-20-18(22)16-9-5-10-17(19)13-16/h2-5,7-10,13H,6,11-12,14H2,1H3,(H,20,22)
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10n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(HUMAN)
BDBM321270
PNG
(N-[3-(isoindolin-2-yl)methylamino)propyl]-4-chloro...)
Show SMILES Clc1ccc(cc1)C(=O)NCCCNCN1Cc2ccccc2C1
Show InChI InChI=1S/C19H22ClN3O/c20-18-8-6-15(7-9-18)19(24)22-11-3-10-21-14-23-12-16-4-1-2-5-17(16)13-23/h1-2,4-9,21H,3,10-14H2,(H,22,24)
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19n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(HUMAN)
BDBM321263
PNG
(N-[3-(benzylmethylamino)propyl]-4-fluorobenzamide ...)
Show SMILES CN(CCCNC(=O)c1ccc(F)cc1)Cc1ccccc1
Show InChI InChI=1S/C18H21FN2O/c1-21(14-15-6-3-2-4-7-15)13-5-12-20-18(22)16-8-10-17(19)11-9-16/h2-4,6-11H,5,12-14H2,1H3,(H,20,22)
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20n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Human)
BDBM321268
PNG
(N-[4-(benzylmethylamino)butyl]-4-chlorobenzamide |...)
Show SMILES CN(CCCCNC(=O)c1ccc(Cl)cc1)Cc1ccccc1
Show InChI InChI=1S/C19H23ClN2O/c1-22(15-16-7-3-2-4-8-16)14-6-5-13-21-19(23)17-9-11-18(20)12-10-17/h2-4,7-12H,5-6,13-15H2,1H3,(H,21,23)
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20n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(HUMAN)
BDBM321277
PNG
(N-[3-(benzylmethylamino)propyl]-3,5-dichlorobenzam...)
Show SMILES CN(CCCNC(=O)c1cc(Cl)cc(Cl)c1)Cc1ccccc1
Show InChI InChI=1S/C18H20Cl2N2O/c1-22(13-14-6-3-2-4-7-14)9-5-8-21-18(23)15-10-16(19)12-17(20)11-15/h2-4,6-7,10-12H,5,8-9,13H2,1H3,(H,21,23)
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23n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(HUMAN)
BDBM321282
PNG
(N-[3-(benzylmethylamino)propyl]-4-cyanobenzamide |...)
Show SMILES CN(CCCNC(=O)c1ccc(cc1)C#N)Cc1ccccc1
Show InChI InChI=1S/C19H21N3O/c1-22(15-17-6-3-2-4-7-17)13-5-12-21-19(23)18-10-8-16(14-20)9-11-18/h2-4,6-11H,5,12-13,15H2,1H3,(H,21,23)
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24n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(HUMAN)
BDBM321280
PNG
(N-[3-(benzylmethylamino)propyl]-4-methoxybenzamide...)
Show SMILES COc1ccc(cc1)C(=O)NCCCN(C)Cc1ccccc1
Show InChI InChI=1S/C19H24N2O2/c1-21(15-16-7-4-3-5-8-16)14-6-13-20-19(22)17-9-11-18(23-2)12-10-17/h3-5,7-12H,6,13-15H2,1-2H3,(H,20,22)
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37n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(HUMAN)
BDBM321279
PNG
(N-[3-(benzylmethylamino)propyl]-3-methoxybenzamide...)
Show SMILES COc1cccc(c1)C(=O)NCCCN(C)Cc1ccccc1
Show InChI InChI=1S/C19H24N2O2/c1-21(15-16-8-4-3-5-9-16)13-7-12-20-19(22)17-10-6-11-18(14-17)23-2/h3-6,8-11,14H,7,12-13,15H2,1-2H3,(H,20,22)
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40n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(HUMAN)
BDBM321271
PNG
(N-[3-(benzylmethylamino)propyl]-2-bromobenzamide |...)
Show SMILES CN(CCCNC(=O)c1ccccc1Br)Cc1ccccc1
Show InChI InChI=1S/C18H21BrN2O/c1-21(14-15-8-3-2-4-9-15)13-7-12-20-18(22)16-10-5-6-11-17(16)19/h2-6,8-11H,7,12-14H2,1H3,(H,20,22)
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42n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(HUMAN)
BDBM321264
PNG
(N-[3-(benzylmethylamino)propyl]-2-chlorobenzamide ...)
Show SMILES CN(CCCNC(=O)c1ccccc1Cl)Cc1ccccc1
Show InChI InChI=1S/C18H21ClN2O/c1-21(14-15-8-3-2-4-9-15)13-7-12-20-18(22)16-10-5-6-11-17(16)19/h2-6,8-11H,7,12-14H2,1H3,(H,20,22)
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47n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Human)
BDBM321277
PNG
(N-[3-(benzylmethylamino)propyl]-3,5-dichlorobenzam...)
Show SMILES CN(CCCNC(=O)c1cc(Cl)cc(Cl)c1)Cc1ccccc1
Show InChI InChI=1S/C18H20Cl2N2O/c1-22(13-14-6-3-2-4-7-14)9-5-8-21-18(23)15-10-16(19)12-17(20)11-15/h2-4,6-7,10-12H,5,8-9,13H2,1H3,(H,21,23)
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48n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Human)
BDBM321260
PNG
(N-[3-(benzylmethylamino)propyl]-4-butylbenzamide |...)
Show SMILES CCCCc1ccc(cc1)C(=O)NCCCN(C)Cc1ccccc1
Show InChI InChI=1S/C22H30N2O/c1-3-4-9-19-12-14-21(15-13-19)22(25)23-16-8-17-24(2)18-20-10-6-5-7-11-20/h5-7,10-15H,3-4,8-9,16-18H2,1-2H3,(H,23,25)
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49n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Human)
BDBM321276
PNG
(N-[3-(benzylmethylamino)propyl]-3,4-dichlorobenzam...)
Show SMILES CN(CCCNC(=O)c1ccc(Cl)c(Cl)c1)Cc1ccccc1
Show InChI InChI=1S/C18H20Cl2N2O/c1-22(13-14-6-3-2-4-7-14)11-5-10-21-18(23)15-8-9-16(19)17(20)12-15/h2-4,6-9,12H,5,10-11,13H2,1H3,(H,21,23)
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59n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Human)
BDBM321262
PNG
(N-[3-(benzylmethylamino)propyl]-4-trifluoromethylb...)
Show SMILES CN(CCCNC(=O)c1ccc(cc1)C(F)(F)F)Cc1ccccc1
Show InChI InChI=1S/C19H21F3N2O/c1-24(14-15-6-3-2-4-7-15)13-5-12-23-18(25)16-8-10-17(11-9-16)19(20,21)22/h2-4,6-11H,5,12-14H2,1H3,(H,23,25)
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98n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Human)
BDBM321284
PNG
(N-(2-(benzyl(methyl)amino)ethyl)-2,4-dichlorobenza...)
Show SMILES CN(CCNC(=O)c1ccc(Cl)cc1Cl)Cc1ccccc1
Show InChI InChI=1S/C17H18Cl2N2O/c1-21(12-13-5-3-2-4-6-13)10-9-20-17(22)15-8-7-14(18)11-16(15)19/h2-8,11H,9-10,12H2,1H3,(H,20,22)
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110n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Human)
BDBM321273
PNG
(N-[3-(benzylmethylamino)propyl]-4-bromobenzamide |...)
Show SMILES CN(CCCNC(=O)c1ccc(Br)cc1)Cc1ccccc1
Show InChI InChI=1S/C18H21BrN2O/c1-21(14-15-6-3-2-4-7-15)13-5-12-20-18(22)16-8-10-17(19)11-9-16/h2-4,6-11H,5,12-14H2,1H3,(H,20,22)
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160n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Human)
BDBM321259
PNG
(N-[3-(benzylmethylamino)propyl]-4-propylbenzamide ...)
Show SMILES CCCc1ccc(cc1)C(=O)NCCCN(C)Cc1ccccc1
Show InChI InChI=1S/C21H28N2O/c1-3-8-18-11-13-20(14-12-18)21(24)22-15-7-16-23(2)17-19-9-5-4-6-10-19/h4-6,9-14H,3,7-8,15-17H2,1-2H3,(H,22,24)
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160n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Human)
BDBM321285
PNG
(N-(2-(benzyl(methyl)amino)ethyl)-4-cyanobenzamide ...)
Show SMILES CN(CCNC(=O)c1ccc(cc1)C#N)Cc1ccccc1
Show InChI InChI=1S/C18H19N3O/c1-21(14-16-5-3-2-4-6-16)12-11-20-18(22)17-9-7-15(13-19)8-10-17/h2-10H,11-12,14H2,1H3,(H,20,22)
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170n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Human)
BDBM321267
PNG
(N-[3-(benzylmethylamino)propyl]-4-chlorobenzamide ...)
Show SMILES CN(CCCNC(=O)c1ccc(Cl)cc1)Cc1ccccc1
Show InChI InChI=1S/C18H21ClN2O/c1-21(14-15-6-3-2-4-7-15)13-5-12-20-18(22)16-8-10-17(19)11-9-16/h2-4,6-11H,5,12-14H2,1H3,(H,20,22)
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190n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Human)
BDBM321269
PNG
(N-[3-(N-methyl-2-phenylethylamino)propyl]-4-chloro...)
Show SMILES CN(CCCNC(=O)c1ccc(Cl)cc1)CCc1ccccc1
Show InChI InChI=1S/C19H23ClN2O/c1-22(15-12-16-6-3-2-4-7-16)14-5-13-21-19(23)17-8-10-18(20)11-9-17/h2-4,6-11H,5,12-15H2,1H3,(H,21,23)
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200n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Human)
BDBM321274
PNG
(N-[3-(benzylmethylamino)propyl]-2,3-dichlorobenzam...)
Show SMILES CN(CCCNC(=O)c1cccc(Cl)c1Cl)Cc1ccccc1
Show InChI InChI=1S/C18H20Cl2N2O/c1-22(13-14-7-3-2-4-8-14)12-6-11-21-18(23)15-9-5-10-16(19)17(15)20/h2-5,7-10H,6,11-13H2,1H3,(H,21,23)
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310n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Human)
BDBM321275
PNG
(N-[3-(benzylmethylamino)propyl]-2,4-dichlorobenzam...)
Show SMILES CN(CCCNC(=O)c1ccc(Cl)cc1Cl)Cc1ccccc1
Show InChI InChI=1S/C18H20Cl2N2O/c1-22(13-14-6-3-2-4-7-14)11-5-10-21-18(23)16-9-8-15(19)12-17(16)20/h2-4,6-9,12H,5,10-11,13H2,1H3,(H,21,23)
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310n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Human)
BDBM321265
PNG
(N-[3-(benzylmethylamino)propyl]-3-chlorobenzamide ...)
Show SMILES CN(CCCNC(=O)c1cccc(Cl)c1)Cc1ccccc1
Show InChI InChI=1S/C18H21ClN2O/c1-21(14-15-7-3-2-4-8-15)12-6-11-20-18(22)16-9-5-10-17(19)13-16/h2-5,7-10,13H,6,11-12,14H2,1H3,(H,20,22)
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340n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Human)
BDBM321272
PNG
(N-[3-(benzylmethylamino)propyl]-3-bromobenzamide |...)
Show SMILES CN(CCCNC(=O)c1cccc(Br)c1)Cc1ccccc1
Show InChI InChI=1S/C18H21BrN2O/c1-21(14-15-7-3-2-4-8-15)12-6-11-20-18(22)16-9-5-10-17(19)13-16/h2-5,7-10,13H,6,11-12,14H2,1H3,(H,20,22)
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350n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Human)
BDBM321283
PNG
(N-[3-(benzylmethylamino)propyl]-4-nitrobenzamide |...)
Show SMILES CN(CCCNC(=O)c1ccc(cc1)[N+]([O-])=O)Cc1ccccc1
Show InChI InChI=1S/C18H21N3O3/c1-20(14-15-6-3-2-4-7-15)13-5-12-19-18(22)16-8-10-17(11-9-16)21(23)24/h2-4,6-11H,5,12-14H2,1H3,(H,19,22)
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360n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Human)
BDBM321263
PNG
(N-[3-(benzylmethylamino)propyl]-4-fluorobenzamide ...)
Show SMILES CN(CCCNC(=O)c1ccc(F)cc1)Cc1ccccc1
Show InChI InChI=1S/C18H21FN2O/c1-21(14-15-6-3-2-4-7-15)13-5-12-20-18(22)16-8-10-17(19)11-9-16/h2-4,6-11H,5,12-14H2,1H3,(H,20,22)
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470n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Human)
BDBM321266
PNG
(N-[3-(2-(N-methylbenzyl)amino)ethyl]-4-chlorobenza...)
Show SMILES CNc1ccccc1CNCCCNC(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C18H22ClN3O/c1-20-17-6-3-2-5-15(17)13-21-11-4-12-22-18(23)14-7-9-16(19)10-8-14/h2-3,5-10,20-21H,4,11-13H2,1H3,(H,22,23)
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850n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Human)
BDBM321280
PNG
(N-[3-(benzylmethylamino)propyl]-4-methoxybenzamide...)
Show SMILES COc1ccc(cc1)C(=O)NCCCN(C)Cc1ccccc1
Show InChI InChI=1S/C19H24N2O2/c1-21(15-16-7-4-3-5-8-16)14-6-13-20-19(22)17-9-11-18(23-2)12-10-17/h3-5,7-12H,6,13-15H2,1-2H3,(H,20,22)
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>1.00E+3n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Human)
BDBM321264
PNG
(N-[3-(benzylmethylamino)propyl]-2-chlorobenzamide ...)
Show SMILES CN(CCCNC(=O)c1ccccc1Cl)Cc1ccccc1
Show InChI InChI=1S/C18H21ClN2O/c1-21(14-15-8-3-2-4-9-15)13-7-12-20-18(22)16-10-5-6-11-17(16)19/h2-6,8-11H,7,12-14H2,1H3,(H,20,22)
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>1.20E+3n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Human)
BDBM321271
PNG
(N-[3-(benzylmethylamino)propyl]-2-bromobenzamide |...)
Show SMILES CN(CCCNC(=O)c1ccccc1Br)Cc1ccccc1
Show InChI InChI=1S/C18H21BrN2O/c1-21(14-15-8-3-2-4-9-15)13-7-12-20-18(22)16-10-5-6-11-17(16)19/h2-6,8-11H,7,12-14H2,1H3,(H,20,22)
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>1.20E+3n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Human)
BDBM321282
PNG
(N-[3-(benzylmethylamino)propyl]-4-cyanobenzamide |...)
Show SMILES CN(CCCNC(=O)c1ccc(cc1)C#N)Cc1ccccc1
Show InChI InChI=1S/C19H21N3O/c1-22(15-17-6-3-2-4-7-17)13-5-12-21-19(23)18-10-8-16(14-20)9-11-18/h2-4,6-11H,5,12-13,15H2,1H3,(H,21,23)
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>1.20E+3n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Human)
BDBM321279
PNG
(N-[3-(benzylmethylamino)propyl]-3-methoxybenzamide...)
Show SMILES COc1cccc(c1)C(=O)NCCCN(C)Cc1ccccc1
Show InChI InChI=1S/C19H24N2O2/c1-21(15-16-8-4-3-5-9-16)13-7-12-20-19(22)17-10-6-11-18(14-17)23-2/h3-6,8-11,14H,7,12-13,15H2,1-2H3,(H,20,22)
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>1.20E+3n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Human)
BDBM321286
PNG
(N-(2-(benzyl(methyl)amino)ethyl)-4-nitrobenzamide ...)
Show SMILES CN(CCNC(=O)c1ccc(cc1)[N+]([O-])=O)Cc1ccccc1
Show InChI InChI=1S/C17H19N3O3/c1-19(13-14-5-3-2-4-6-14)12-11-18-17(21)15-7-9-16(10-8-15)20(22)23/h2-10H,11-13H2,1H3,(H,18,21)
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1.40E+3n/an/an/an/an/an/an/an/a



UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)

US Patent


Assay Description
The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...


US Patent US10179761 (2019)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%