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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332059 (Morpholin-4-yl-[1-(5-phenyl-pyrimidin-2-yl)-spiro[...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332090 (US10189854, Compound 44 | [1-[5-(2-Fluorophenyl)-p...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332095 (US10189854, Compound 49 | [1-(5-Phenyl-pyrimidin-2...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332098 (US10189854, Compound 52 | [1-[5-(2-Fluoro-5-methyl...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332101 (4-[1-(5-Phenyl-pyrimidin-2-yl)-spiro[1,2-dihydro-i...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332128 (US10189854, Compound 84 | [1-[5-(2-Fluorophenyl)-p...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332162 (US10189854, Compound 121 | [1-[5-(2-Fluorophenyl)-...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332177 (US10189854, Compound 136 | [1-[5-(1-Methyl-1H-pyrr...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332195 (US10189854, Compound 154 | [1-[5-(2,4-Dimethyl-thi...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332227 (4-[1-[5-(3-Fluorophenyl)-pyrimidin-2-yl]-spiro[1,2...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332237 (1-[5-(3-Carbamoyl-phenyl)-pyrimidin-2-yl]-N-(2-hyd...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332249 (US10189854, Compound 212) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332264 (US10189854, Compound 227) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332267 (US10189854, Compound 230) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332268 (US10189854, Compound 231) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332270 (US10189854, Compound 233) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332294 (US10189854, Compound 258) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332299 (US10189854, Compound 263) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332310 (US10189854, Compound 274) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332325 (US10189854, Compound 289) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332330 (US10189854, Compound 294) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332331 (US10189854, Compound 295) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332334 (US10189854, Compound 298) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332339 (US10189854, Compound 303) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332349 (US10189854, Compound 313) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332370 (US10189854, Compound 334) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332373 (US10189854, Compound 337) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332374 (US10189854, Compound 338) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332379 (US10189854, Compound 343) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332380 (US10189854, Compound 344) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332384 (US10189854, Compound 348) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332055 (US10189854, Compound 3 | [1-[5-(1-Fluorophenyl)-py...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332063 (US10189854, Compound 15 | [1-[5-(2,3-Difluoro-phen...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332075 (US10189854, Compound 27 | [1-[5-(2,6-Difluoro-phen...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332081 (US10189854, Compound 34 | US10189854, Compound 94 ...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332103 (US10189854, Compound 57 | [1-[5-(3-Fluorophenyl)-p...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332111 (3-Fluoro-N,N-dimethyl-4-[2-[6-(morpholine-4-carbon...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332147 (US10189854, Compound 103 | [1-[5-(2-Fluorophenyl)-...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332151 ((2,5-Diazabicyclo[2.2.1]heptan-2-yl)-[1-[5-(2-fluo...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332157 (US10189854, Compound 114 | [(3R)-3-Amino-pyrrolidi...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332158 (US10189854, Compound 115 | [(3S)-3-Amino-pyrrolidi...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332160 (3-[2-[6-[(3R)-3-Amino-pyrrolidine-1-carbonyl]-spir...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332166 (1-[5-(3-Fluorophenyl)-pyrimidin-2-yl]-N,N-dimethyl...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332192 (US10189854, Compound 151 | [1-[5-(6-Fluoro-pyridin...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332197 (5-[2-[6-(Morpholine-4-carbonyl)-spiro[1,2-dihydro-...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332200 (US10189854, Compound 159 | [1-[5-(2-Methyl-pyridin...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332202 (5-[2-[6-(Morpholine-4-carbonyl)-spiro[1,2-dihydro-...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332207 (US10189854, Compound 166 | [1-[5-(3,5-Difluoro-pyr...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332208 (US10189854, Compound 167 | [1-[5-(2-Methyl-pyridin...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332229 (Morpholin-4-yl-[1-(5-pyrimidin-4-yl-pyrimidin-2-yl...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Gruenenthal GmbH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
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