Search and Browse
Download
Enter Data
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332524 (4-(1-(2-chloro-6- (trifluoromethyl)benzoyl)-6- (3-...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet  | PC cid PC sid UniChem | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332433 (4-(1-(2- chloro-6- cyclopropyl- benzoyl)-1H- indaz...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332431 (4-(1-(2- chloro-6- cyclopropyl- benzoyl)-4- fluoro...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332523 (4-(6-(azetidine-1-carbonyl)-1-(2-chloro-6-(trifluo...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332432 (4-(1-(2- chloro-6- cyclobutyl- benzoyl)-1H- pyrazo...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332520 (4-(1-(2-chloro-6-cyclobutylbenzoyl)-1H-pyrazolo[4,...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332522 (4-(1-(2-chloro-6- (trifluoromethyl)benzoyl)- 6-(ox...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332430 (4-(4-chloro-1- (2-chloro-6- cyclopropyl- benzoyl)-...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332437 (4-(1-(2-chloro- 6-(trifluoro- methyl)benzoyl)- 6-(...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332517 (4-(1-(2-chloro-6- cyclopropylbenzoyl)-1H- indazol-...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332518 (4-(1-(2-chloro-6- cyclopropylbenzoyl)-4- fluoro-1H...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332482 (4-(1-(2-chloro-6-(trifluoromethyl)benzoyl)-6-(4H-1...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332411 (4-(1-(2-chloro-6-cyclopropylbenzoyl)-1H-pyrazolo[4...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332511 (4-(5-acetamido-1-(2-chloro-6-(trifluoromethyl)-ben...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332434 (4-(1-(2- chloro-6- morpholino- benzoyl)-1H- pyrazo...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332516 (4-(1-(2-chloro-6-cyclopropylbenzoyl)-1H-pyrazolo[4...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332519 (4-(1-(2-chloro-6- cyclopropylbenzoyl)-1H- pyrrolo[...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332521 (4-(1-(2-chloro-6-(trifluoromethyl)benzoyl)-6-(1,3-...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332534 (4-(1-(2-chloro-6-cyclopentylbenzoyl)-1H-pyrazolo[4...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332477 (4-(1-(2-chloro-6-(trifluoromethyl)benzoyl)-6-(1-me...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332510 (4-(1-(2-chloro-6-(trifluoromethyl)benzoyl)-6-(meth...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332470 (4-(1-(2-chloro- 6- (trifluoromethyl) benzoyl)-6-(5...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332462 (4-(1-(2-chloro-6- (trifluoromethyl) benzoyl)-6- (c...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332484 (4-(1-(2-chloro-6- (trifluoromethyl) benzoyl)-6-(1-...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332436 (4-(1-(2-chloro-6- (trifluoromethyl) benzoyl)-6- ((...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332535 (4-(1-(2-chloro-6-cyclobutylbenzoyl)-1H-pyrazolo[4,...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332435 (4-(1-(2-chloro-6-(trifluoromethyl)benzoyl)-6-(morp...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332426 (4-(1-(2-chloro- 6-vinyl- benzoyl)-1H- pyrazolo[4,3...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332483 (4-(1-(2-chloro-6- (trifluoromethyl) benzoyl)-6-(5-...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332473 (4-(6-(3-aminoprop-1-ynyl)-1-(2-chloro-6-(trifluoro...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332476 (4-(1-(2-chloro-6-(trifluoromethyl)benzoyl)-6-(5-(h...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332456 (4-(6-(2-carboxyethylamino)-1-(2-chloro-6-(trifluor...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332443 (4-(1-(2-chloro-6- (trifluoromethyl) benzoyl)-6-(ox...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332478 (4-(1-(2-chloro-6-(trifluoromethyl)benzoyl)-6-(oxaz...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332455 (4-(1-(2-chloro-6-(trifluoromethyl)benzoyl)-6-(2-ox...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332479 (4-(6-(5-bromooxazol-2-yl)-1-(2-chloro-6-(trifluoro...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332428 (4-(1-(6-chloro- 2,3-dihydro- benzo[b][1,4] dioxine...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332514 (4-(1-(2-chloro-6-(trifluoromethyl)benzoyl)-2-methy...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332427 (4-(1-(2-chloro- 6-(prop-1-en- 2-yl)benzoyl)- 1H-py...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332492 (4-(6-[4- (aminomethyl) pyridin-2-yl]-1- {[2-chloro...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332490 (4-[1-{[2-chloro- 6- (trifluoromethyl) phenyl]carbo...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 39 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332429 (4-(1-(2- (dimethyl- amino)-6- methyl- benzoyl)-1H-...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332471 (4-(1-(2-chloro-6-(trifluoromethyl)benzoyl)-6-(3-hy...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332451 (4-(6-acetamido- 1-(2-chloro-6- (trifluoromethyl) b...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332410 (4-(1-(2-chloro-6-(trifluoromethyl)benzoyl)-4-formy...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332409 ((E)-4-(1-(2-chloro-6-(prop-1-enyl)benzoyl)-1H-pyra...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332507 (4-(1-(2-chloro-6-(trifluoromethyl)benzoyl)-6-(2,5-...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 53 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332419 (4-{1-[(2-bromo- 3-methyl- phenyl) carbonyl]-1H- in...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332468 (4-(1-(2-chloro- 6-(trifluoromethyl) benzoyl)-6-(ox...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 57 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332420 (4-[1-(2,3- dihydro-1H- inden-4- ylcarbonyl)-1H- in...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 58 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332532 (4-(1-(2-chloro-6-(trifluoromethyl)benzoyl)-6-(dicy...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332469 (4-(1-(2-chloro-6-(trifluoromethyl)benzoyl)-6-(5-me...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 63 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332450 (4-(1-(2-chloro- 6-(trifluoro- methyl)benzoyl)- 6-(...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 64 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332459 (4-(1-(2-chloro-6-(trifluoromethyl)benzoyl)-6-(morp...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 69 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332513 (4-(1-(2-chloro-6-(trifluoromethyl)benzoyl)-6-(2-me...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332525 (4-(6-(2-amino-2-oxoethyl)-1-(2-chloro-6-(trifluoro...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 81 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332454 (4-(1-(2-chloro-6-(trifluoromethyl)benzoyl)-6-(2-ox...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 85 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332461 (4-(1-(2-chloro-6- (trifluoromethyl) benzoyl)-6- (c...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 87 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332472 (4-(1-(2-chloro-6-(trifluoromethyl)benzoyl)-6-(3-hy...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 105 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332481 (4-(1-(2-chloro-6-(trifluoromethyl)benzoyl)-6-(5-ox...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332442 (4-(1-(2-chloro-6- (trifluoromethyl) benzoyl)-6- (c...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332474 (4-(1-(2-chloro-6-(trifluoromethyl)benzoyl)-6-ethyn...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 137 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332465 (4-(1-(2-chloro-6-(trifluoromethyl)benzoyl)-6-(cycl...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 143 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332447 (4-(1-(2-chloro-6-(trifluoromethyl)benzoyl)-6-(N-me...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 153 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332488 (4-(1-{[2-chloro- 6- (trifluoromethyl) phenyl]carbo...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 155 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332424 (4-{1-[(2- bromo-3- chlorophenyl) carbonyl]-1H- ind...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 159 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332508 (4-(5-(tert-butoxycarbonylamino)-1-(2-chloro-6-(tri...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 182 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332509 (4-(6-(tert-butoxycarbonylamino)-1-(2-chloro-6-(tri...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 191 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332512 (4-(1-(2-chloro-6-(trifluoromethyl)benzoyl)-5-(meth...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 209 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332467 (4-(1-(2-chloro- 6-(trifluoromethyl) benzoyl)-6- (h...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 218 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332464 (4-(1-(2-chloro-6- (trifluoromethyl) benzoyl)-6-(3,...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 222 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332458 (4-(1-(2-chloro-6- (trifluoromethyl) benzoyl)-6-(2-...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 224 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332526 (4-(6-(2-(azetidin-1-yl)-2- oxoethyl)-1-(2-chloro-6...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 225 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332475 (4-(1-(2-chloro-6-(trifluoromethyl)benzoyl)-6-(3-me...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 241 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332463 (4-(1-(2-chloro-6- (trifluoromethyl) benzoyl)-6-(3-...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 245 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332446 (4-(1-(2-chloro-6-(trifluoromethyl)benzoyl)-6-(meth...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 255 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332493 (4-(1-{[2-chloro- 6- (trifluoromethyl) phenyl]carbo...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 274 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332466 (4-(1-(2-chloro-6-(trifluoromethyl)benzoyl)-6-(cycl...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 283 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332448 (4-(1-(2-chloro- 6-(trifluoro- methyl)benzoyl)- 6-(...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 314 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332460 (3-(4-carboxyphenyl)-1-(2-chloro-6-(trifluoromethyl...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 317 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332417 (3-fluoro-4-[1- (naphthalen-1- ylcarbonyl)- 1H-inda...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 335 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332491 (4-[1-{[2-chloro- 6- (trifluoromethyl) phenyl]carbo...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 356 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332527 (4-(1-(2-chloro-6- (trifluoromethyl)benzoyl)- 6-(2-...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 363 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332515 (4-(2-methyl-1-(2- (trifluoromethyl)benzoyl)- 1H-in...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 384 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332528 (4-(1-(2-chloro-6- (trifluoromethyl)benzoyl)- 6-(2-...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 458 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332453 (4-(1-(2-chloro- 6-(trifluoro- methyl)benzoyl)- 6-(...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 491 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332449 (4-(1-(2-chloro- 6-(trifluoro- methyl)benzoyl)- 6-(...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 493 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332440 (4-(1-(2-chloro-6-(trifluoromethyl) benzoyl)-6-(3-h...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332485 (4-(1-(2-chloro-6-trifluoromethylbenzoyl)-6-(thiazo...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 754 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332529 (4-(1-(2-chloro-6-(trifluoromethyl)benzoyl)-6-(oxet...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 784 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332530 (4-(1-(2-chloro-4-(2-methoxyethoxy)-6-methylbenzoyl...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 821 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332506 (4-(1-(2-chloro-6-(trifluoromethyl)benzoyl)-6-(meth...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 876 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332480 ((E)-4-(1-(2-chloro-6-(trifluoromethyl)benzoyl)-6-(...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 888 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332422 (4-[1-(2,3- dihydro-1- benzofuran-7- ylcarbonyl)- 1...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 969 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332444 (4-(1-(2-chloro-6- (trifluoromethyl) benzoyl)-6-(3-...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332441 (4-(6-(azetidin-1-yl)- 1-(2-chloro-6- (trifluoromet...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.33E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332489 (4-(1-{[2-chloro- 6- (trifluoromethyl) phenyl]carbo...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.44E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332438 (2-acetamido-4-(1-(2-chloro-6-(trifluoromethyl) ben...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.47E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332423 (4-[1-(1- benzofuran-7- ylcarbonyl)- 1H-indazol- 3-...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.48E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332452 (4-(1-(2-chloro- 6-(trifluoro- methyl)benzoyl)- 6-(...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332457 (4-(1-(2-chloro-6- (trifluoromethyl) benzoyl)-6-(3-...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332439 (4-(1-(2-chloro-6- (trifluoromethyl) benzoyl)-1H- p...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332533 (4-(1-(4-amino-2-chloro-6-methylbenzoyl)-1H-pyrazol...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.32E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332445 (4-(1-(2-chloro-6- (trifluoromethyl) benzoyl)-6- mo...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.32E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332413 (3-fluoro-4-(1- (2-phenyl- propanoyl)- 1H-indazol-3...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.32E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332414 (3-fluoro-4-[1- (methoxy- acetyl)-1H- indazol-3-yl]...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.57E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332486 (4-[1-{[2-chloro- 6- (trifluoromethyl) phenyl]carbo...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.61E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332494 (4-[1-{[2-chloro- 6- (trifluoromethyl) phenyl]carbo...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.39E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332531 (4-(1-(2-chloro-6-methyl-4-morpholinobenzoyl)-1H-py...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.87E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332416 (3-fluoro-4-{1- [(2-oxo- pyrrolidin-1- yl)acetyl]-1...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332487 (4-[1-{[2-chloro- 6- (trifluoromethyl) phenyl]carbo...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332418 (3-fluoro-4-{1- [(1-methyl-1H- indol-2-yl) carbonyl...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332502 (4-[1-{[2-chloro-6- (trifluoromethyl) phenyl]carbon...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332499 (4-[1-{[2-chloro-6- (trifluoromethyl) phenyl]carbon...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332495 (4-(1-(2-chloro-6-trifluoromethylbenzoyl)-6-(pyridi...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332421 (4-(1-{[3- (tertbutoxy- carbonyl)-3- azabicyclo [3....) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332498 (4-[1-{[2-chloro-6- (trifluoromethyl) phenyl]carbon...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332496 (4-(1-{[2-chloro-6- (trifluoromethyl) phenyl]carbon...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332412 (3-fluoro-4-[1-(pyridin-2-ylcarbonyl)-1H-indazol-3-...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332504 (4-[1-{[2-chloro-6- (trifluoromethyl) phenyl]carbon...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332415 (3-fluoro-4-[1- (pyridin-3- ylcarbonyl)- 1H-indazol...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332503 (4-[1-{[2-chloro-6- (trifluoromethyl) phenyl]carbon...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332501 (4-[1-{[2-chloro-6- (trifluoromethyl) phenyl]carbon...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332500 (4-(1-{[2-chloro-6- (trifluoromethyl) phenyl]carbon...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332425 (3-fluoro-4-(1- (tetrahydro- furan-2- carbonyl)-1H-...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332505 (4-(1-(2-chloro- 6-trifluoromethylbenzoyl)- 6-(4-hy...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM332497 (4-[1-{[2-chloro-6- (trifluoromethyl) phenyl]carbon...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I... | US Patent US10196354 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
