Compile Data Set for Download or QSAR
maximum 50k data
Found 41 Enz. Inhib. hit(s) with all data for entry = 1610
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332747(2-(4-(5-cyanopyrazin-2-yl)piperazin-1-yl)-6-fluoro...)
Affinity DataIC50:  3nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332743(US10196381, Compound (33))
Affinity DataIC50:  5nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332748(2-(4-(2-cyanopyrimidin-5-yl)piperazin-1-yl)-6-fluo...)
Affinity DataIC50:  6nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332735(6-fluoro-2-(4-(5-methylcarbamoylpyrazin-2-yl)piper...)
Affinity DataIC50:  7nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332736(2-(4-(5-ethylcarbamoylpyrazin-2-yl)piperazin-1-yl)...)
Affinity DataIC50:  7nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332751(2-(4-(2-dimethylcarbamoylpyrimidin-5-yl)piperazin-...)
Affinity DataIC50:  8nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332741(6-fluoro-2-(4-(6-trifluoromethylpyridazin-3-yl)pip...)
Affinity DataIC50:  8nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332746(2-(4-(5-dimethylcarbamoylpyrazin-2-yl)piperazin-1-...)
Affinity DataIC50:  8nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332725(US10196381, Compound (16))
Affinity DataIC50:  9nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332750(2-(4-(2-ethylcarbamoylpyrimidin-5-yl)piperazin-1-y...)
Affinity DataIC50:  9nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332728(2-(4-(5-cyanopyrimidin-2-yl)piperazin-1-yl)-6-fluo...)
Affinity DataIC50:  9nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332740(6-fluoro-2-(4-(5-(morpholin-4-acyl)pyrazin-2-yl)pi...)
Affinity DataIC50:  9nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332749(6-fluoro-2-(4-(2-methylcarbamoylpyrimidin-2-yl)pip...)
Affinity DataIC50:  9nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332745(6-fluoro-2-(4-(5-trifluoromethylpyrazin-2-yl)piper...)
Affinity DataIC50:  9nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332731(6-fluoro-2-(4-(5-methylcarbamoylpyrimidin-2-yl)pip...)
Affinity DataIC50:  10nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332739(6-fluoro-2-(4-(5-(pyrrolin-1-acyl)pyrazin-2-yl)pip...)
Affinity DataIC50:  12nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332732(6-fluoro-2-(4-(6-methylcarbamoylpyridazin-3-yl)pip...)
Affinity DataIC50:  12nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332737(6-fluoro-2-(4-(5-isopropylcarbamoylpyrazin-2-yl)pi...)
Affinity DataIC50:  14nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332742(6-fluoro-2-(4-(6-trifluoromethylpyridine-3-yl)pipe...)
Affinity DataIC50:  15nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332714(2-(4-(pyrimidin-4-yl)piperazin-1-yl)-1H-benzimidaz...)
Affinity DataIC50:  17nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332738(2-(4-(5-t-butylcarbamoylpyrazin-2-yl)piperazin-1-y...)
Affinity DataIC50:  25nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332721(2-(4-(5-carbamoylpyridin-2-yl)piperazin-1-yl)-1H-b...)
Affinity DataIC50:  25nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332718(2-(4-(5-methylcarbamoylpyridin-2-yl)piperazin-1-yl...)
Affinity DataIC50:  25nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332726(6-fluoro-2-(4-(5-fluoropyrimidin-2-yl)piperazin-1-...)
Affinity DataIC50:  26nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332723(2-(4-(5-cyanopyrimidin-2-yl)piperazin-1-yl)-1H-ben...)
Affinity DataIC50:  28nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332727(2-(4-(5-(dimethylcarbamoyl)pyridin-2-yl)piperazin-...)
Affinity DataIC50:  30nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332734(6-fluoro-2-(4-(5-methylcarbamoylpyridin-2-yl)piper...)
Affinity DataIC50:  45nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332729(6-fluoro-2-(4-(3-methylcarbamoylpyridin-2-yl)piper...)
Affinity DataIC50:  48nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332708(US10196381, Compound (1))
Affinity DataIC50:  48nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332722(2-(4-(2-trifluoromethylpyridin-4-yl)piperazin-1-yl...)
Affinity DataIC50:  49nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332709(US10196381, Compound (2))
Affinity DataIC50:  49nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332724(2-(4-(5-dimethylcarbamoylpyridin-2-yl)piperazin-1-...)
Affinity DataIC50:  54nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332717(2-(4-(6-trifluoromethylpyrimidin-4-yl)piperazin-1-...)
Affinity DataIC50:  55nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332744(6-fluoro-2-(4-(5-trifluoromethylpyrimidin-2-yl)pip...)
Affinity DataIC50:  56nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332730(6-fluoro-2-(4-(5-trifluoromethylpyridin-2-yl)piper...)
Affinity DataIC50:  68nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332712(2-(4-(5-methoxypyrimidin-2-yl)piperazin-1-yl)-1H-b...)
Affinity DataIC50:  74nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332713(2-(4-(5-aminopyrimidin-2-yl)piperazin-1-yl)-1H-ben...)
Affinity DataIC50:  98nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332711(2-(4-(5-acetamidopyrimidin-2-yl)piperazin-1-yl)-1H...)
Affinity DataIC50:  106nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332716(2-(4-(4-trifluoromethylpyrimidin-2-yl)piperazin-1-...)
Affinity DataIC50:  217nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332715(2-(4-(3-ethylaminopyridin-2-yl)piperazin-1-yl)-1H-...)
Affinity DataIC50:  928nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332710(2-(4-(5-ethylaminopyrimidin-2-yl)piperazin-1-yl)-1...)
Affinity DataIC50:  3.58E+3nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent