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Patent code US10196385

Compile Data Set for Download or QSAR
Found 3 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Probable G-protein coupled receptor 142


(Homo sapiens (Human))
BDBM332762
PNG
(Cis-(chiral)-N-[(2-[5-(1,4-Dimethyl-1H-imidazol-5-...)
Show SMILES CN([C@@H]1CCO[C@@H](C1)c1nnc([nH]1)-c1c(C)ncn1C)C(=O)c1cccc(c1)C(F)(F)F
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 43.5n/an/an/an/a



Eli Lilly and Company

US Patent


Assay Description
HEK293 cells expressing human GPR142 are maintained in DMEM supplemented with 10% FBS and 800 μg/ml G418 (Geneticin) at 37 C. and 5% CO2. The c...


US Patent US10196385 (2019)


BindingDB Entry DOI: 10.7270/Q2FJ2JVR
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142


(Homo sapiens (Human))
BDBM332764
PNG
(Cis-(chiral)-3-Chloro-N-[2- [5-(1,4-dimethyl-1H- i...)
Show SMILES CN([C@@H]1CCO[C@@H](C1)c1nnc([nH]1)-c1c(C)ncn1C)C(=O)c1cccc(Cl)c1
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 27.2n/an/an/an/a



Eli Lilly and Company

US Patent


Assay Description
HEK293 cells expressing human GPR142 are maintained in DMEM supplemented with 10% FBS and 800 μg/ml G418 (Geneticin) at 37 C. and 5% CO2. The c...


US Patent US10196385 (2019)


BindingDB Entry DOI: 10.7270/Q2FJ2JVR
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142


(Homo sapiens (Human))
BDBM332763
PNG
(Cis-(chiral)-N-[2-[5-(1,4- Dimethyl-1H-imidazol-5-...)
Show SMILES CN([C@@H]1CCO[C@@H](C1)c1nnc([nH]1)-c1c(C)ncn1C)C(=O)c1cccc(OC(F)(F)F)c1
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 30.1n/an/an/an/a



Eli Lilly and Company

US Patent


Assay Description
HEK293 cells expressing human GPR142 are maintained in DMEM supplemented with 10% FBS and 800 μg/ml G418 (Geneticin) at 37 C. and 5% CO2. The c...


US Patent US10196385 (2019)


BindingDB Entry DOI: 10.7270/Q2FJ2JVR
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%