Affinity Data by Patent

Patent code US10196385

Found 3 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Probable G-protein coupled receptor 142 (Homo sapiens (Human))	BDBM332762 (Cis-(chiral)-N-[(2-[5-(1,4-Dimethyl-1H-imidazol-5-...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	43.5	n/a	n/a	n/a	n/a
Eli Lilly and Company US Patent					Assay Description HEK293 cells expressing human GPR142 are maintained in DMEM supplemented with 10% FBS and 800 μg/ml G418 (Geneticin) at 37� C. and 5% CO2. The c...				US Patent US10196385 (2019) BindingDB Entry DOI: 10.7270/Q2FJ2JVR
Eli Lilly and Company US Patent					More data for this Ligand-Target Pair
Probable G-protein coupled receptor 142 (Homo sapiens (Human))	BDBM332764 (Cis-(chiral)-3-Chloro-N-[2- [5-(1,4-dimethyl-1H- i...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	27.2	n/a	n/a	n/a	n/a
Eli Lilly and Company US Patent					Assay Description HEK293 cells expressing human GPR142 are maintained in DMEM supplemented with 10% FBS and 800 μg/ml G418 (Geneticin) at 37� C. and 5% CO2. The c...				US Patent US10196385 (2019) BindingDB Entry DOI: 10.7270/Q2FJ2JVR
Eli Lilly and Company US Patent					More data for this Ligand-Target Pair
Probable G-protein coupled receptor 142 (Homo sapiens (Human))	BDBM332763 (Cis-(chiral)-N-[2-[5-(1,4- Dimethyl-1H-imidazol-5-...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	30.1	n/a	n/a	n/a	n/a
Eli Lilly and Company US Patent					Assay Description HEK293 cells expressing human GPR142 are maintained in DMEM supplemented with 10% FBS and 800 μg/ml G418 (Geneticin) at 37� C. and 5% CO2. The c...				US Patent US10196385 (2019) BindingDB Entry DOI: 10.7270/Q2FJ2JVR
Eli Lilly and Company US Patent					More data for this Ligand-Target Pair

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* indicates data uncertainty>20%