Compile Data Set for Download or QSAR
maximum 50k data
Found 120 Enz. Inhib. hit(s) with all data for entry = 1622
TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333026(US10196391, Example 26)
Affinity DataIC50:  61nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333095(US10196391, Example 95)
Affinity DataIC50:  61nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333099(US10196391, Example 99)
Affinity DataIC50:  100nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333017(6-(3,4-difluoro-5-methoxy-phenyl)-2-(2-pyridyl)-7,...)
Affinity DataIC50:  154nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333117(US10196391, Example 117)
Affinity DataIC50:  157nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333080(US10196391, Example 80)
Affinity DataIC50:  160nMAssay Description:The assay employs real-time qPCR (TaqMan) to directly measure extracellular HBV DNA copy number. HepG2.2.15 cells were plated in 96-well microtiter p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333113(US10196391, Example 113)
Affinity DataIC50:  161nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333096(US10196391, Example 96)
Affinity DataIC50:  162nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333091(US10196391, Example 91)
Affinity DataIC50:  198nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333108(US10196391, Example 108)
Affinity DataIC50:  263nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333077(US10196391, Example 77)
Affinity DataIC50:  265nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333098(US10196391, Example 98)
Affinity DataIC50:  268nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333100(US10196391, Example 100)
Affinity DataIC50:  278nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333079(US10196391, Example 79)
Affinity DataIC50:  288nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333093(US10196391, Example 93)
Affinity DataIC50:  314nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333021(US10196391, Example 21)
Affinity DataIC50:  321nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333071(6-(3-fluoro-4-methoxy-2-pyridyl)-2-(2-pyridyl)-7,8...)
Affinity DataIC50:  330nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333115(6-(4-chloro-6-methoxy-2-pyridyl)-2-pyrimidin-2-yl-...)
Affinity DataIC50:  352nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333111(US10196391, Example 111)
Affinity DataIC50:  362nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333060(US10196391, Example 60)
Affinity DataIC50:  371nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333033(US10196391, Example 33)
Affinity DataIC50:  390nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333028(US10196391, Example 28)
Affinity DataIC50:  455nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333019(US10196391, Example 19)
Affinity DataIC50:  461nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333041(US10196391, Example 41)
Affinity DataIC50:  500nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333116(6-(2-chloro-6-methoxy-4-pyridyl)-2-pyrimidin-2-yl-...)
Affinity DataIC50:  530nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333023(US10196391, Example 23)
Affinity DataIC50:  549nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333112(US10196391, Example 112)
Affinity DataIC50:  553nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333042(US10196391, Example 42)
Affinity DataIC50:  566nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333094(US10196391, Example 94)
Affinity DataIC50:  660nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333040(US10196391, Example 40)
Affinity DataIC50:  669nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333101(US10196391, Example 101)
Affinity DataIC50:  674nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333022(US10196391, Example 22)
Affinity DataIC50:  750nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333034(US10196391, Example 34)
Affinity DataIC50:  874nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333090(US10196391, Example 90)
Affinity DataIC50:  933nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333069(6-(5-chloro-2-methoxy-pyrimidin-4-yl)-2-(2-pyridyl...)
Affinity DataIC50:  999nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333013(US10196391, Example 13)
Affinity DataIC50:  1.04E+3nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333049(US10196391, Example 49)
Affinity DataIC50:  1.07E+3nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333114(US10196391, Example 114)
Affinity DataIC50:  1.17E+3nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333055(US10196391, Example 55)
Affinity DataIC50:  1.18E+3nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333104(US10196391, Example 104)
Affinity DataIC50:  1.24E+3nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333062(US10196391, Example 62)
Affinity DataIC50:  1.34E+3nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333106(US10196391, Example 106)
Affinity DataIC50:  1.34E+3nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333048(US10196391, Example 48)
Affinity DataIC50:  1.38E+3nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333072(US10196391, Example 72)
Affinity DataIC50:  1.43E+3nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333110(6-(4,6-difluoro-2-pyridyl)-2-pyrimidin-2-yl-7,8-di...)
Affinity DataIC50:  1.44E+3nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333068(6-(5-chloro-4-methoxy-pyrimidin-2-yl)-2-(2-pyridyl...)
Affinity DataIC50:  1.47E+3nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333076(US10196391, Example 76)
Affinity DataIC50:  1.51E+3nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333036(US10196391, Example 36)
Affinity DataIC50:  1.54E+3nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333070(6-(5-fluoro-4-methoxy-2-pyridyl)-2-(2-pyridyl)-7,8...)
Affinity DataIC50:  1.55E+3nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333053(US10196391, Example 53)
Affinity DataIC50:  1.56E+3nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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