Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with all data for entry = 1876
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Celtaxsys

US Patent
LigandPNGBDBM345819(US10202362, Compound T2.2)
Affinity DataIC50:  1.80nMAssay Description:LTB4 formed was quantified with the HTRF assay in which free LTB4 competes with LTB4-XL665 conjugate (acceptor) for anti-LTB4 monoclonal antibody lab...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Celtaxsys

US Patent
LigandPNGBDBM345818(US10202362, Compound T2.1)
Affinity DataIC50:  2.10nMAssay Description:LTB4 formed was quantified with the HTRF assay in which free LTB4 competes with LTB4-XL665 conjugate (acceptor) for anti-LTB4 monoclonal antibody lab...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Celtaxsys

US Patent
LigandPNGBDBM345818(US10202362, Compound T2.1)
Affinity DataIC50:  7.10nMAssay Description:In brief, the enzyme (29 nM) was incubated with L-alanine-p-nitroanilide (1 mM) in 50 mM HEPES (pH 7.5), 100 mM KCL, 1% DMSO in the absence or presen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Celtaxsys

US Patent
LigandPNGBDBM345819(US10202362, Compound T2.2)
Affinity DataIC50:  22nMAssay Description:In brief, the enzyme (29 nM) was incubated with L-alanine-p-nitroanilide (1 mM) in 50 mM HEPES (pH 7.5), 100 mM KCL, 1% DMSO in the absence or presen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent