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Patent code US10202379

Compile Data Set for Download or QSAR

Found 784 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346986
PNG
(US10202379, Reference Example 730)
Show SMILES C[C@@H](N1CN([C@@H]2c3ccccc3SCc3cccc(C#C)c23)n2ccc(=O)c(O)c2C1=O)C(F)(F)F
Show InChI InChI=1S/C26H20F3N3O3S/c1-3-16-7-6-8-17-13-36-20-10-5-4-9-18(20)22(21(16)17)32-14-30(15(2)26(27,28)29)25(35)23-24(34)19(33)11-12-31(23)32/h1,4-12,15,22,34H,13-14H2,2H3/t15-,22-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 2.52n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346979
PNG
(US10202379, Reference Example 719)
Show SMILES C[C@@H](N1CN([C@@H]2c3ccccc3SCc3c(Cl)cccc23)n2cc(CO)c(=O)c(O)c2C1=O)C(F)(F)F
Show InChI InChI=1S/C25H21ClF3N3O4S/c1-13(25(27,28)29)30-12-32(31-9-14(10-33)22(34)23(35)21(31)24(30)36)20-15-6-4-7-18(26)17(15)11-37-19-8-3-2-5-16(19)20/h2-9,13,20,33,35H,10-12H2,1H3/t13-,20+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 2.60n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346964
PNG
(US10202379, Reference Example 666)
Show SMILES C[C@@H](N1CN([C@@H]2c3ccccc3SCc3cccc(Cl)c23)n2cc(CO)c(=O)c(O)c2C1=O)C(F)(F)F
Show InChI InChI=1S/C25H21ClF3N3O4S/c1-13(25(27,28)29)30-12-32(31-9-15(10-33)22(34)23(35)21(31)24(30)36)20-16-6-2-3-8-18(16)37-11-14-5-4-7-17(26)19(14)20/h2-9,13,20,33,35H,10-12H2,1H3/t13-,20-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 3.36n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346968
PNG
(US10202379, Reference Example 691)
Show SMILES C[C@@H](N1CN([C@@H]2c3ccccc3SCc3cccc(C4CC4)c23)n2ccc(=O)c(O)c2C1=O)C(F)(F)F
Show InChI InChI=1S/C27H24F3N3O3S/c1-15(27(28,29)30)31-14-33(32-12-11-20(34)25(35)24(32)26(31)36)23-19-6-2-3-8-21(19)37-13-17-5-4-7-18(22(17)23)16-9-10-16/h2-8,11-12,15-16,23,35H,9-10,13-14H2,1H3/t15-,23-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 3.67n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346984
PNG
(US10202379, Reference Example 726)
Show SMILES C[C@@H](N1CN([C@@H]2c3cccc(F)c3SCc3cccc(C#C)c23)n2ccc(=O)c(O)c2C1=O)C(F)(F)F
Show InChI InChI=1S/C26H19F4N3O3S/c1-3-15-6-4-7-16-12-37-24-17(8-5-9-18(24)27)21(20(15)16)33-13-31(14(2)26(28,29)30)25(36)22-23(35)19(34)10-11-32(22)33/h1,4-11,14,21,35H,12-13H2,2H3/t14-,21-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 3.74n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346923
PNG
(US10202379, Reference Example 602)
Show SMILES C[C@@H](N1CN([C@H]2c3ccc(F)cc3CSc3c(Cl)cccc23)n2ccc(=O)c(O)c2C1=O)C(F)(F)F
Show InChI InChI=1S/C24H18ClF4N3O3S/c1-12(24(27,28)29)30-11-32(31-8-7-18(33)21(34)20(31)23(30)35)19-15-6-5-14(26)9-13(15)10-36-22-16(19)3-2-4-17(22)25/h2-9,12,19,34H,10-11H2,1H3/t12-,19+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 5n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346931
PNG
(US10202379, Reference Example 619)
Show SMILES C[C@@H](N1CN([C@H]2c3ccc(F)cc3CSc3c(Br)cccc23)n2ccc(=O)c(O)c2C1=O)C(F)(F)F
Show InChI InChI=1S/C24H18BrF4N3O3S/c1-12(24(27,28)29)30-11-32(31-8-7-18(33)21(34)20(31)23(30)35)19-15-6-5-14(26)9-13(15)10-36-22-16(19)3-2-4-17(22)25/h2-9,12,19,34H,10-11H2,1H3/t12-,19+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 5n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346983
PNG
(US10202379, Reference Example 724)
Show SMILES CCc1cccc2CSc3c(F)cccc3[C@@H](N3CN([C@H](C)C(F)(F)F)C(=O)c4c(O)c(=O)ccn34)c12
Show InChI InChI=1S/C26H23F4N3O3S/c1-3-15-6-4-7-16-12-37-24-17(8-5-9-18(24)27)21(20(15)16)33-13-31(14(2)26(28,29)30)25(36)22-23(35)19(34)10-11-32(22)33/h4-11,14,21,35H,3,12-13H2,1-2H3/t14-,21-/m1/s1
PDB

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UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 5.07n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346995
PNG
(US10202379, Reference Example 772)
Show SMILES C[C@@H](N1CN([C@@H]2c3ccc(F)cc3SCc3cccc(Cl)c23)n2ccc(=O)c(O)c2C1=O)C(F)(F)F
Show InChI InChI=1S/C24H18ClF4N3O3S/c1-12(24(27,28)29)30-11-32(31-8-7-17(33)22(34)21(31)23(30)35)20-15-6-5-14(26)9-18(15)36-10-13-3-2-4-16(25)19(13)20/h2-9,12,20,34H,10-11H2,1H3/t12-,20-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 5.22n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346978
PNG
(US10202379, Reference Example 716)
Show SMILES C[C@@H](N1CN([C@@H]2c3ccccc3SCc3c(F)c(F)ccc23)n2cc(Cl)c(=O)c(O)c2C1=O)C(F)(F)F
Show InChI InChI=1S/C24H17ClF5N3O3S/c1-11(24(28,29)30)31-10-33(32-8-15(25)21(34)22(35)20(32)23(31)36)19-12-6-7-16(26)18(27)14(12)9-37-17-5-3-2-4-13(17)19/h2-8,11,19,35H,9-10H2,1H3/t11-,19+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 5.54n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346976
PNG
(US10202379, Reference Example 711)
Show SMILES C[C@@H](N1CN([C@@H]2c3ccccc3SCc3c(F)c(F)ccc23)n2ccc(=O)c(O)c2C1=O)C(F)(F)F
Show InChI InChI=1S/C24H18F5N3O3S/c1-12(24(27,28)29)30-11-32(31-9-8-17(33)22(34)21(31)23(30)35)20-13-6-7-16(25)19(26)15(13)10-36-18-5-3-2-4-14(18)20/h2-9,12,20,34H,10-11H2,1H3/t12-,20+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 5.57n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346987
PNG
(US10202379, Reference Example 731)
Show SMILES CCc1cccc2CSc3ccccc3[C@@H](N3CN([C@H](C)C(F)(F)F)C(=O)c4c(O)c(=O)ccn34)c12
Show InChI InChI=1S/C26H24F3N3O3S/c1-3-16-7-6-8-17-13-36-20-10-5-4-9-18(20)22(21(16)17)32-14-30(15(2)26(27,28)29)25(35)23-24(34)19(33)11-12-31(23)32/h4-12,15,22,34H,3,13-14H2,1-2H3/t15-,22-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 5.76n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346994
PNG
(US10202379, Reference Example 771)
Show SMILES C[C@@H](N1CN([C@@H]2c3cccc(F)c3SCc3cccc(Br)c23)n2ccc(=O)c(O)c2C1=O)C(F)(F)F
Show InChI InChI=1S/C24H18BrF4N3O3S/c1-12(24(27,28)29)30-11-32(31-9-8-17(33)21(34)20(31)23(30)35)19-14-5-3-7-16(26)22(14)36-10-13-4-2-6-15(25)18(13)19/h2-9,12,19,34H,10-11H2,1H3/t12-,19-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 5.89n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346932
PNG
(US10202379, Reference Example 621)
Show SMILES C[C@@H](N1CN([C@@H]2c3cccc(F)c3SCc3cccc(Cl)c23)n2ccc(=O)c(O)c2C1=O)C(F)(F)F
Show InChI InChI=1S/C24H18ClF4N3O3S/c1-12(24(27,28)29)30-11-32(31-9-8-17(33)21(34)20(31)23(30)35)19-14-5-3-7-16(26)22(14)36-10-13-4-2-6-15(25)18(13)19/h2-9,12,19,34H,10-11H2,1H3/t12-,19-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 6n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346980
PNG
(US10202379, Reference Example 720 | US10202379, Re...)
Show SMILES C[C@@H](N1CN([C@@H]2c3cccc(C)c3SCc3cccc(C)c23)n2ccc(=O)c(O)c2C1=O)C(F)(F)F
Show InChI InChI=1S/C26H24F3N3O3S/c1-14-6-4-8-17-12-36-24-15(2)7-5-9-18(24)21(20(14)17)32-13-30(16(3)26(27,28)29)25(35)22-23(34)19(33)10-11-31(22)32/h4-11,16,21,34H,12-13H2,1-3H3/t16-,21-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 6.96n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346821
PNG
(US10202379, Reference Example 446)
Show SMILES C[C@@H](N1CN([C@H]2c3ccc(Cl)cc3CSc3ccccc23)n2ccc(=O)c(O)c2C1=O)C(F)(F)F
Show InChI InChI=1S/C24H19ClF3N3O3S/c1-13(24(26,27)28)29-12-31(30-9-8-18(32)22(33)21(30)23(29)34)20-16-7-6-15(25)10-14(16)11-35-19-5-3-2-4-17(19)20/h2-10,13,20,33H,11-12H2,1H3/t13-,20+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 7n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346840
PNG
(US10202379, Reference Example 470)
Show SMILES C[C@@H](N1CN([C@H]2c3ccc(F)cc3CSc3c(F)cccc23)n2ccc(=O)c(O)c2C1=O)C(F)(F)F
Show InChI InChI=1S/C24H18F5N3O3S/c1-12(24(27,28)29)30-11-32(31-8-7-18(33)21(34)20(31)23(30)35)19-15-6-5-14(25)9-13(15)10-36-22-16(19)3-2-4-17(22)26/h2-9,12,19,34H,10-11H2,1H3/t12-,19+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 8n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346956
PNG
(US10202379, Reference Example 654)
Show SMILES C[C@@H](N1CN([C@@H]2c3ccccc3SCc3cccc(Br)c23)n2ccc(=O)c(O)c2C1=O)C(F)(F)F
Show InChI InChI=1S/C24H19BrF3N3O3S/c1-13(24(26,27)28)29-12-31(30-10-9-17(32)22(33)21(30)23(29)34)20-15-6-2-3-8-18(15)35-11-14-5-4-7-16(25)19(14)20/h2-10,13,20,33H,11-12H2,1H3/t13-,20-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 8n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346917
PNG
(US10202379, Reference Example 594)
Show SMILES C[C@@H](N1CN([C@H]2c3cccc(F)c3CSc3c(Cl)cccc23)n2ccc(=O)c(O)c2C1=O)C(F)(F)F
Show InChI InChI=1S/C24H18ClF4N3O3S/c1-12(24(27,28)29)30-11-32(31-9-8-18(33)21(34)20(31)23(30)35)19-13-4-3-7-17(26)15(13)10-36-22-14(19)5-2-6-16(22)25/h2-9,12,19,34H,10-11H2,1H3/t12-,19+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 11n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346970
PNG
(US10202379, Reference Example 704)
Show SMILES C[C@@H](N1CN([C@@H]2c3ccccc3SCc3c(F)c(F)ccc23)n2cc(C)c(=O)c(O)c2C1=O)C(F)(F)F
Show InChI InChI=1S/C25H20F5N3O3S/c1-12-9-32-21(23(35)22(12)34)24(36)31(13(2)25(28,29)30)11-33(32)20-14-7-8-17(26)19(27)16(14)10-37-18-6-4-3-5-15(18)20/h3-9,13,20,35H,10-11H2,1-2H3/t13-,20+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 11.1n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346828
PNG
(US10202379, Reference Example 454)
Show SMILES C[C@@H](N1CN([C@H]2c3ccc(F)cc3CSc3ccccc23)n2ccc(=O)c(O)c2C1=O)C(F)(F)F
Show InChI InChI=1S/C24H19F4N3O3S/c1-13(24(26,27)28)29-12-31(30-9-8-18(32)22(33)21(30)23(29)34)20-16-7-6-15(25)10-14(16)11-35-19-5-3-2-4-17(19)20/h2-10,13,20,33H,11-12H2,1H3/t13-,20+/m1/s1
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SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346837
PNG
(US10202379, Reference Example 463)
Show SMILES C[C@@H](N1CN([C@@H]2c3ccccc3SCc3c(Br)cccc23)n2ccc(=O)c(O)c2C1=O)C(F)(F)F
Show InChI InChI=1S/C24H19BrF3N3O3S/c1-13(24(26,27)28)29-12-31(30-10-9-18(32)22(33)21(30)23(29)34)20-14-6-4-7-17(25)16(14)11-35-19-8-3-2-5-15(19)20/h2-10,13,20,33H,11-12H2,1H3/t13-,20+/m1/s1
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n/an/a 12n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346965
PNG
(US10202379, Reference Example 668)
Show SMILES C[C@@H](N1CN([C@H]2c3cc(F)c(F)cc3CSc3ccccc23)n2ccc(=O)c(O)c2C1=O)C(F)(F)F
Show InChI InChI=1S/C24H18F5N3O3S/c1-12(24(27,28)29)30-11-32(31-7-6-18(33)22(34)21(31)23(30)35)20-14-4-2-3-5-19(14)36-10-13-8-16(25)17(26)9-15(13)20/h2-9,12,20,34H,10-11H2,1H3/t12-,20-/m1/s1
PDB

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n/an/a 12.6n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346820
PNG
(US10202379, Reference Example 445)
Show SMILES C[C@@H](N1CN([C@@H]2c3ccccc3SCc3c(F)cccc23)n2ccc(=O)c(O)c2C1=O)C(F)(F)F
Show InChI InChI=1S/C24H19F4N3O3S/c1-13(24(26,27)28)29-12-31(30-10-9-18(32)22(33)21(30)23(29)34)20-14-6-4-7-17(25)16(14)11-35-19-8-3-2-5-15(19)20/h2-10,13,20,33H,11-12H2,1H3/t13-,20+/m1/s1
PDB

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n/an/a 13n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346816
PNG
(US10202379, Reference Example 433)
Show SMILES C[C@@H](N1CN([C@H]2c3ccc(Br)cc3CSc3ccccc23)n2ccc(=O)c(O)c2C1=O)C(F)(F)F
Show InChI InChI=1S/C24H19BrF3N3O3S/c1-13(24(26,27)28)29-12-31(30-9-8-18(32)22(33)21(30)23(29)34)20-16-7-6-15(25)10-14(16)11-35-19-5-3-2-4-17(19)20/h2-10,13,20,33H,11-12H2,1H3/t13-,20+/m1/s1
PDB

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n/an/a 14n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346744
PNG
(US10202379, Reference Example 347)
Show SMILES CN1CN(C2c3ccccc3CSc3c(Cl)cccc23)n2ccc(=O)c(O)c2C1=O
Show InChI InChI=1S/C22H18ClN3O3S/c1-24-12-26(25-10-9-17(27)20(28)19(25)22(24)29)18-14-6-3-2-5-13(14)11-30-21-15(18)7-4-8-16(21)23/h2-10,18,28H,11-12H2,1H3
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SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346990
PNG
(US10202379, Reference Example 752)
Show SMILES C[C@@H](N1CN([C@@H]2c3ccccc3SCc3cccc(N(C)C)c23)n2ccc(=O)c(O)c2C1=O)C(F)(F)F
Show InChI InChI=1S/C26H25F3N4O3S/c1-15(26(27,28)29)31-14-33(32-12-11-19(34)24(35)23(32)25(31)36)22-17-8-4-5-10-20(17)37-13-16-7-6-9-18(21(16)22)30(2)3/h4-12,15,22,35H,13-14H2,1-3H3/t15-,22-/m1/s1
PDB

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n/an/a 14.2n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346866
PNG
(US10202379, Reference Example 509)
Show SMILES CC(C)N1CN(C2c3ccccc3CSc3ccccc23)n2cc(CF)c(=O)c(O)c2C1=O
Show InChI InChI=1S/C25H24FN3O3S/c1-15(2)27-14-29(28-12-17(11-26)23(30)24(31)22(28)25(27)32)21-18-8-4-3-7-16(18)13-33-20-10-6-5-9-19(20)21/h3-10,12,15,21,31H,11,13-14H2,1-2H3
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n/an/a 15n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346967
PNG
(US10202379, Reference Example 686)
Show SMILES C[C@@H](N1CN(C2c3ccccc3CCc3cccc(Cl)c23)n2ccc(=O)c(O)c2C1=O)C(F)(F)F
Show InChI InChI=1S/C25H21ClF3N3O3/c1-14(25(27,28)29)30-13-32(31-12-11-19(33)23(34)22(31)24(30)35)21-17-7-3-2-5-15(17)9-10-16-6-4-8-18(26)20(16)21/h2-8,11-12,14,21,34H,9-10,13H2,1H3/t14-,21?/m1/s1
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n/an/a 15.1n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346993
PNG
(US10202379, Reference Example 768)
Show SMILES C[C@@H](N1CN([C@@H]2c3cccc(C)c3SCc3cccc(Cl)c23)n2ccc(=O)c(O)c2C1=O)C(F)(F)F
Show InChI InChI=1S/C25H21ClF3N3O3S/c1-13-5-3-7-16-20(19-15(11-36-23(13)16)6-4-8-17(19)26)32-12-30(14(2)25(27,28)29)24(35)21-22(34)18(33)9-10-31(21)32/h3-10,14,20,34H,11-12H2,1-2H3/t14-,20-/m1/s1
PDB

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n/an/a 15.3n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346738
PNG
(US10202379, Reference Example 341)
Show SMILES Oc1c2C(=O)N(CN(C3c4ccccc4CSc4c(Cl)cccc34)n2ccc1=O)C1CC1
Show InChI InChI=1S/C24H20ClN3O3S/c25-18-7-3-6-17-20(16-5-2-1-4-14(16)12-32-23(17)18)28-13-26(15-8-9-15)24(31)21-22(30)19(29)10-11-27(21)28/h1-7,10-11,15,20,30H,8-9,12-13H2
PDB

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SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346919
PNG
(US10202379, Reference Example 598)
Show SMILES C[C@@H](N1CN([C@@H]2c3ccc(F)cc3SCc3cccc(F)c23)n2ccc(=O)c(O)c2C1=O)C(F)(F)F
Show InChI InChI=1S/C24H18F5N3O3S/c1-12(24(27,28)29)30-11-32(31-8-7-17(33)22(34)21(31)23(30)35)20-15-6-5-14(25)9-18(15)36-10-13-3-2-4-16(26)19(13)20/h2-9,12,20,34H,10-11H2,1H3/t12-,20-/m1/s1
PDB

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SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346839
PNG
(US10202379, Reference Example 469)
Show SMILES C[C@@H](N1CN([C@H]2c3cccc(F)c3CSc3c(F)cccc23)n2ccc(=O)c(O)c2C1=O)C(F)(F)F
Show InChI InChI=1S/C24H18F5N3O3S/c1-12(24(27,28)29)30-11-32(31-9-8-18(33)21(34)20(31)23(30)35)19-13-4-2-6-16(25)15(13)10-36-22-14(19)5-3-7-17(22)26/h2-9,12,19,34H,10-11H2,1H3/t12-,19+/m1/s1
PDB

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n/an/a 16n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346674
PNG
(US10202379, Reference Example 273)
Show SMILES CN1CN(C2c3ccccc3CCc3ccccc23)n2ccc(=O)c(O)c2C1=O
Show InChI InChI=1S/C23H21N3O3/c1-24-14-26(25-13-12-19(27)22(28)21(25)23(24)29)20-17-8-4-2-6-15(17)10-11-16-7-3-5-9-18(16)20/h2-9,12-13,20,28H,10-11,14H2,1H3
PDB

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n/an/a 16n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346812
PNG
(US10202379, Reference Example 429)
Show SMILES C[C@@H](N1CN([C@@H]2c3ccccc3SCc3cccc(Cl)c23)n2ccc(=O)c(O)c2C1=O)C(F)(F)F
Show InChI InChI=1S/C24H19ClF3N3O3S/c1-13(24(26,27)28)29-12-31(30-10-9-17(32)22(33)21(30)23(29)34)20-15-6-2-3-8-18(15)35-11-14-5-4-7-16(25)19(14)20/h2-10,13,20,33H,11-12H2,1H3/t13-,20-/m1/s1
PDB

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SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346977
PNG
(US10202379, Reference Example 712)
Show SMILES C[C@@H](N1CN([C@H]2c3ccccc3CSc3ccccc23)n2cc(CO)c(=O)c(O)c2C1=O)C(F)(F)F
Show InChI InChI=1S/C25H22F3N3O4S/c1-14(25(26,27)28)29-13-31(30-10-16(11-32)22(33)23(34)21(30)24(29)35)20-17-7-3-2-6-15(17)12-36-19-9-5-4-8-18(19)20/h2-10,14,20,32,34H,11-13H2,1H3/t14-,20+/m1/s1
PDB

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n/an/a 16.4n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346669
PNG
(US10202379, Reference Example 268)
Show SMILES CCOCCN1CN(C2c3ccccc3CCc3ccccc23)n2ccc(=O)c(O)c2C1=O
Show InChI InChI=1S/C26H27N3O4/c1-2-33-16-15-27-17-29(28-14-13-22(30)25(31)24(28)26(27)32)23-20-9-5-3-7-18(20)11-12-19-8-4-6-10-21(19)23/h3-10,13-14,23,31H,2,11-12,15-17H2,1H3
PDB

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SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346702
PNG
(US10202379, Reference Example 304)
Show SMILES Oc1c2C(=O)N(CCF)CN(C3c4ccccc4CSc4ccccc34)n2ccc1=O
Show InChI InChI=1S/C23H20FN3O3S/c24-10-12-25-14-27(26-11-9-18(28)22(29)21(26)23(25)30)20-16-6-2-1-5-15(16)13-31-19-8-4-3-7-17(19)20/h1-9,11,20,29H,10,12-14H2
PDB

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SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346963
PNG
(US10202379, Reference Example 665)
Show SMILES C[C@@H](N1CN([C@@H]2c3ccccc3SCc3cccc(C)c23)n2ccc(=O)c(O)c2C1=O)C(F)(F)F
Show InChI InChI=1S/C25H22F3N3O3S/c1-14-6-5-7-16-12-35-19-9-4-3-8-17(19)21(20(14)16)31-13-29(15(2)25(26,27)28)24(34)22-23(33)18(32)10-11-30(22)31/h3-11,15,21,33H,12-13H2,1-2H3/t15-,21-/m1/s1
PDB

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n/an/a 18n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346971
PNG
(US10202379, Reference Example 706)
Show SMILES C[C@@H](N1CN([C@@H]2c3ccccc3SCc3c(F)c(F)ccc23)n2cc(C(C)=O)c(=O)c(O)c2C1=O)C(F)(F)F
Show InChI InChI=1S/C26H20F5N3O4S/c1-12(35)16-9-33-22(24(37)23(16)36)25(38)32(13(2)26(29,30)31)11-34(33)21-14-7-8-18(27)20(28)17(14)10-39-19-6-4-3-5-15(19)21/h3-9,13,21,37H,10-11H2,1-2H3/t13-,21+/m1/s1
PDB

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n/an/a 18.6n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346718
PNG
(US10202379, Reference Example 321)
Show SMILES CN1CN(C2c3ccccc3CSc3ccccc23)n2ccc(=O)c(O)c2C1=O
Show InChI InChI=1S/C22H19N3O3S/c1-23-13-25(24-11-10-17(26)21(27)20(24)22(23)28)19-15-7-3-2-6-14(15)12-29-18-9-5-4-8-16(18)19/h2-11,19,27H,12-13H2,1H3
PDB

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SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346710
PNG
(US10202379, Reference Example 312)
Show SMILES CCOCCN1CN(C2c3ccccc3CSc3ccccc23)n2ccc(=O)c(O)c2C1=O
Show InChI InChI=1S/C25H25N3O4S/c1-2-32-14-13-26-16-28(27-12-11-20(29)24(30)23(27)25(26)31)22-18-8-4-3-7-17(18)15-33-21-10-6-5-9-19(21)22/h3-12,22,30H,2,13-16H2,1H3
PDB

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UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 19n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346732
PNG
(US10202379, Reference Example 335)
Show SMILES COCCN1CN(C2c3ccccc3CSc3c(Cl)cccc23)n2ccc(=O)c(O)c2C1=O
Show InChI InChI=1S/C24H22ClN3O4S/c1-32-12-11-26-14-28(27-10-9-19(29)22(30)21(27)24(26)31)20-16-6-3-2-5-15(16)13-33-23-17(20)7-4-8-18(23)25/h2-10,20,30H,11-14H2,1H3
PDB

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UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 19n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346980
PNG
(US10202379, Reference Example 720 | US10202379, Re...)
Show SMILES C[C@@H](N1CN([C@@H]2c3cccc(C)c3SCc3cccc(C)c23)n2ccc(=O)c(O)c2C1=O)C(F)(F)F
Show InChI InChI=1S/C26H24F3N3O3S/c1-14-6-4-8-17-12-36-24-15(2)7-5-9-18(24)21(20(14)17)32-13-30(16(3)26(27,28)29)25(35)22-23(34)19(33)10-11-31(22)32/h4-11,16,21,34H,12-13H2,1-3H3/t16-,21-/m1/s1
PDB

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UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 19.1n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346980
PNG
(US10202379, Reference Example 720 | US10202379, Re...)
Show SMILES C[C@@H](N1CN([C@@H]2c3cccc(C)c3SCc3cccc(C)c23)n2ccc(=O)c(O)c2C1=O)C(F)(F)F
Show InChI InChI=1S/C26H24F3N3O3S/c1-14-6-4-8-17-12-36-24-15(2)7-5-9-18(24)21(20(14)17)32-13-30(16(3)26(27,28)29)25(35)22-23(34)19(33)10-11-31(22)32/h4-11,16,21,34H,12-13H2,1-3H3/t16-,21-/m1/s1
PDB

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UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 19.2n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346966
PNG
(US10202379, Reference Example 682)
Show SMILES Oc1c2C(=O)N3CCOC[C@@H]3N([C@@H]3c4ccccc4SCc4cccc(Cl)c34)n2ccc1=O
Show InChI InChI=1S/C24H20ClN3O4S/c25-16-6-3-4-14-13-33-18-7-2-1-5-15(18)21(20(14)16)28-19-12-32-11-10-26(19)24(31)22-23(30)17(29)8-9-27(22)28/h1-9,19,21,30H,10-13H2/t19-,21+/m0/s1
PDB

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UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 19.7n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346975
PNG
(US10202379, Reference Example 710)
Show SMILES CC(O)c1cn2N(CN([C@H](C)C(F)(F)F)C(=O)c2c(O)c1=O)[C@@H]1c2ccccc2SCc2cccc(Cl)c12
Show InChI InChI=1S/C26H23ClF3N3O4S/c1-13(34)17-10-32-22(24(36)23(17)35)25(37)31(14(2)26(28,29)30)12-33(32)21-16-7-3-4-9-19(16)38-11-15-6-5-8-18(27)20(15)21/h3-10,13-14,21,34,36H,11-12H2,1-2H3/t13?,14-,21-/m1/s1
PDB

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UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 20.6n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346730
PNG
(US10202379, Reference Example 333)
Show SMILES COCCN1CN(C2c3ccccc3CSc3ccc(Cl)cc23)n2ccc(=O)c(O)c2C1=O
Show InChI InChI=1S/C24H22ClN3O4S/c1-32-11-10-26-14-28(27-9-8-19(29)23(30)22(27)24(26)31)21-17-5-3-2-4-15(17)13-33-20-7-6-16(25)12-18(20)21/h2-9,12,21,30H,10-11,13-14H2,1H3
PDB

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UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 21n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346988
PNG
(US10202379, Reference Example 741)
Show SMILES C[C@@H](N1CN([C@@H]2c3ccccc3SCc3cccc(c23)C(F)(F)F)n2ccc(=O)c(O)c2C1=O)C(F)(F)F
Show InChI InChI=1S/C25H19F6N3O3S/c1-13(24(26,27)28)32-12-34(33-10-9-17(35)22(36)21(33)23(32)37)20-15-6-2-3-8-18(15)38-11-14-5-4-7-16(19(14)20)25(29,30)31/h2-10,13,20,36H,11-12H2,1H3/t13-,20-/m1/s1
PDB

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UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 21n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
Transcription initiation factor TFIID subunit 1


(Homo sapiens (Human))
BDBM346934
PNG
(US10202379, Reference Example 623)
Show SMILES C[C@@H](N1CN([C@H]2c3cccc(F)c3CSc3c(C)cccc23)n2ccc(=O)c(O)c2C1=O)C(F)(F)F
Show InChI InChI=1S/C25H21F4N3O3S/c1-13-5-3-7-16-20(15-6-4-8-18(26)17(15)11-36-23(13)16)32-12-30(14(2)25(27,28)29)24(35)21-22(34)19(33)9-10-31(21)32/h3-10,14,20,34H,11-12H2,1-2H3/t14-,20+/m1/s1
PDB

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UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 21n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...


US Patent US10202379 (2019)

More data for this
Ligand-Target Pair
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