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Patent code US10202399

Compile Data Set for Download or QSAR
Found 34 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM196658
PNG
(US10202399, Example 15 | US9212147, 15)
Show SMILES Oc1cc(CCc2ccc(cc2)-c2ccccc2)n[nH]c1=O
Show InChI InChI=1S/C18H16N2O2/c21-17-12-16(19-20-18(17)22)11-8-13-6-9-15(10-7-13)14-4-2-1-3-5-14/h1-7,9-10,12H,8,11H2,(H,19,21)(H,20,22)
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n/an/a 1.20n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...


US Patent US10202399 (2019)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM50431067
PNG
(CHEMBL2338797 | US10202399, Example 18 | US9212147...)
Show SMILES Oc1cc(CCc2cccc(F)c2)n[nH]c1=O
Show InChI InChI=1S/C12H11FN2O2/c13-9-3-1-2-8(6-9)4-5-10-7-11(16)12(17)15-14-10/h1-3,6-7H,4-5H2,(H,14,16)(H,15,17)
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n/an/a 1.40n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...


US Patent US10202399 (2019)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM50431083
PNG
(CHEMBL2338803 | US10202399, Example 24 | US9212147...)
Show SMILES Oc1cc(CCc2cc(F)cc(F)c2)n[nH]c1=O
Show InChI InChI=1S/C12H10F2N2O2/c13-8-3-7(4-9(14)5-8)1-2-10-6-11(17)12(18)16-15-10/h3-6H,1-2H2,(H,15,17)(H,16,18)
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...


US Patent US10202399 (2019)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM50431069
PNG
(CHEMBL2338795 | US10202399, Example 27 | US9212147...)
Show SMILES Oc1cc(CCc2ccccc2F)n[nH]c1=O
Show InChI InChI=1S/C12H11FN2O2/c13-10-4-2-1-3-8(10)5-6-9-7-11(16)12(17)15-14-9/h1-4,7H,5-6H2,(H,14,16)(H,15,17)
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...


US Patent US10202399 (2019)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM50431065
PNG
(CHEMBL2338799 | US10202399, Example 16)
Show SMILES COc1cccc(CCc2cc(O)c(=O)[nH]n2)c1
Show InChI InChI=1S/C13H14N2O3/c1-18-11-4-2-3-9(7-11)5-6-10-8-12(16)13(17)15-14-10/h2-4,7-8H,5-6H2,1H3,(H,14,16)(H,15,17)
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...


US Patent US10202399 (2019)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM196675
PNG
(US10202399, Example 237 | US9212147, 237)
Show SMILES Oc1n[nH]c(COc2ccccc2)cc1=O
Show InChI InChI=1S/C11H10N2O3/c14-10-6-8(12-13-11(10)15)7-16-9-4-2-1-3-5-9/h1-6H,7H2,(H,12,14)(H,13,15)
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...


US Patent US10202399 (2019)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM196661
PNG
(US10202399, Example 21 | US9212147, 21 | US9290456...)
Show SMILES Oc1cc(CCc2ccc(F)cc2F)n[nH]c1=O
Show InChI InChI=1S/C12H10F2N2O2/c13-8-3-1-7(10(14)5-8)2-4-9-6-11(17)12(18)16-15-9/h1,3,5-6H,2,4H2,(H,15,17)(H,16,18)
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...


US Patent US10202399 (2019)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM196674
PNG
(US10202399, Example 232 | US9212147, 232)
Show SMILES Oc1n[nH]c(COc2cccc(F)c2)cc1=O
Show InChI InChI=1S/C11H9FN2O3/c12-7-2-1-3-9(4-7)17-6-8-5-10(15)11(16)14-13-8/h1-5H,6H2,(H,13,15)(H,14,16)
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...


US Patent US10202399 (2019)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM196671
PNG
(US10202399, Example 56 | US9212147, 56)
Show SMILES Oc1cc(CCc2cccc3ccccc23)n[nH]c1=O
Show InChI InChI=1S/C16H14N2O2/c19-15-10-13(17-18-16(15)20)9-8-12-6-3-5-11-4-1-2-7-14(11)12/h1-7,10H,8-9H2,(H,17,19)(H,18,20)
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...


US Patent US10202399 (2019)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM50431066
PNG
(CHEMBL2338798 | US10202399, Example 17 | US9212147...)
Show SMILES Oc1cc(CCc2cccc(c2)C(F)(F)F)n[nH]c1=O
Show InChI InChI=1S/C13H11F3N2O2/c14-13(15,16)9-3-1-2-8(6-9)4-5-10-7-11(19)12(20)18-17-10/h1-3,6-7H,4-5H2,(H,17,19)(H,18,20)
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...


US Patent US10202399 (2019)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM196660
PNG
(US10202399, Example 20 | US9212147, 20)
Show SMILES Cc1cccc(CCc2cc(O)c(=O)[nH]n2)c1
Show InChI InChI=1S/C13H14N2O2/c1-9-3-2-4-10(7-9)5-6-11-8-12(16)13(17)15-14-11/h2-4,7-8H,5-6H2,1H3,(H,14,16)(H,15,17)
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...


US Patent US10202399 (2019)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM196670
PNG
(US10202399, Example 52 | US9212147, 52)
Show SMILES Oc1cc(CCCCc2ccccc2)n[nH]c1=O
Show InChI InChI=1S/C14H16N2O2/c17-13-10-12(15-16-14(13)18)9-5-4-8-11-6-2-1-3-7-11/h1-3,6-7,10H,4-5,8-9H2,(H,15,17)(H,16,18)
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...


US Patent US10202399 (2019)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM347109
PNG
(US10202399, Example 254)
Show SMILES Oc1cc(COc2ccc(Cl)cc2)n[nH]c1=O
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...


US Patent US10202399 (2019)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM50431084
PNG
(CHEMBL2338802 | US10202399, Example 14)
Show SMILES COc1ccc(CCc2cc(O)c(=O)[nH]n2)cc1
Show InChI InChI=1S/C13H14N2O3/c1-18-11-6-3-9(4-7-11)2-5-10-8-12(16)13(17)15-14-10/h3-4,6-8H,2,5H2,1H3,(H,14,16)(H,15,17)
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...


US Patent US10202399 (2019)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM196673
PNG
(US10202399, Example 231 | US9212147, 231)
Show SMILES Oc1n[nH]c(COc2ccc(F)cc2)cc1=O
Show InChI InChI=1S/C11H9FN2O3/c12-7-1-3-9(4-2-7)17-6-8-5-10(15)11(16)14-13-8/h1-5H,6H2,(H,13,15)(H,14,16)
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...


US Patent US10202399 (2019)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM50431086
PNG
(CHEMBL2338800 | US10202399, Example 212 | US921214...)
Show SMILES Oc1cc(CCc2ccc(F)cc2)n[nH]c1=O
Show InChI InChI=1S/C12H11FN2O2/c13-9-4-1-8(2-5-9)3-6-10-7-11(16)12(17)15-14-10/h1-2,4-5,7H,3,6H2,(H,14,16)(H,15,17)
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...


US Patent US10202399 (2019)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM196662
PNG
(US10202399, Example 22 | US9212147, 22)
Show SMILES Cc1ccccc1CCc1cc(O)c(=O)[nH]n1
Show InChI InChI=1S/C13H14N2O2/c1-9-4-2-3-5-10(9)6-7-11-8-12(16)13(17)15-14-11/h2-5,8H,6-7H2,1H3,(H,14,16)(H,15,17)
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...


US Patent US10202399 (2019)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM196655
PNG
(US10202399, Example 4 | US9212147, 4)
Show SMILES Oc1n[nH]c(COc2ccccc2F)cc1=O
Show InChI InChI=1S/C11H9FN2O3/c12-8-3-1-2-4-10(8)17-6-7-5-9(15)11(16)14-13-7/h1-5H,6H2,(H,13,15)(H,14,16)
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...


US Patent US10202399 (2019)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM347075
PNG
(US10202399, Example 1)
Show SMILES Oc1n[nH]c(CCc2ccccc2)cc1=O
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...


US Patent US10202399 (2019)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM50431079
PNG
(CHEMBL2338785 | US10202399, Example 9 | US9180122,...)
Show SMILES Oc1cc(CCc2ccccc2)c[nH]c1=O
Show InChI InChI=1S/C13H13NO2/c15-12-8-11(9-14-13(12)16)7-6-10-4-2-1-3-5-10/h1-5,8-9,15H,6-7H2,(H,14,16)
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n/an/a 3.90n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...


US Patent US10202399 (2019)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM50431075
PNG
(CHEMBL2338789 | US10202399, Example 40 | US9290456...)
Show SMILES Oc1cc(CCC2CCCCC2)n[nH]c1=O
Show InChI InChI=1S/C12H18N2O2/c15-11-8-10(13-14-12(11)16)7-6-9-4-2-1-3-5-9/h8-9H,1-7H2,(H,13,15)(H,14,16)
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n/an/a 4.70n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...


US Patent US10202399 (2019)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM50431077
PNG
(CHEMBL2338787 | US10202399, Example 48 | US9212147...)
Show SMILES CC(c1ccccc1)c1cc(O)c(=O)[nH]n1
Show InChI InChI=1S/C12H12N2O2/c1-8(9-5-3-2-4-6-9)10-7-11(15)12(16)14-13-10/h2-8H,1H3,(H,13,15)(H,14,16)
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...


US Patent US10202399 (2019)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM347098
PNG
(US10202399, Example 47)
Show SMILES COc1ccc(SCc2cc(=O)c(O)n[nH]2)cc1
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...


US Patent US10202399 (2019)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM196656
PNG
(US10202399, Example 13 | US9212147, 13)
Show SMILES Cc1ccc(CCc2cc(O)c(=O)[nH]n2)cc1
Show InChI InChI=1S/C13H14N2O2/c1-9-2-4-10(5-3-9)6-7-11-8-12(16)13(17)15-14-11/h2-5,8H,6-7H2,1H3,(H,14,16)(H,15,17)
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...


US Patent US10202399 (2019)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM196664
PNG
(US10202399, Example 25 | US9212147, 25)
Show SMILES CC(C)(C)c1ccc(CCc2cc(O)c(=O)[nH]n2)cc1
Show InChI InChI=1S/C16H20N2O2/c1-16(2,3)12-7-4-11(5-8-12)6-9-13-10-14(19)15(20)18-17-13/h4-5,7-8,10H,6,9H2,1-3H3,(H,17,19)(H,18,20)
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n/an/a 6.60n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...


US Patent US10202399 (2019)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM196667
PNG
(US10202399, Example 29 | US9212147, 29)
Show SMILES CCCCc1cc(O)c(=O)[nH]n1
Show InChI InChI=1S/C8H12N2O2/c1-2-3-4-6-5-7(11)8(12)10-9-6/h5H,2-4H2,1H3,(H,9,11)(H,10,12)
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n/an/a 6.90n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...


US Patent US10202399 (2019)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM347092
PNG
(US10202399, Example 26)
Show SMILES COCCCc1cc(O)c(=O)[nH]n1
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...


US Patent US10202399 (2019)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM210794
PNG
(US10202399, Example 28 | US9290456, 31)
Show SMILES Oc1cc(CCc2ccc(OC(F)(F)F)cc2)n[nH]c1=O
Show InChI InChI=1S/C13H11F3N2O3/c14-13(15,16)21-10-5-2-8(3-6-10)1-4-9-7-11(19)12(20)18-17-9/h2-3,5-7H,1,4H2,(H,17,19)(H,18,20)
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...


US Patent US10202399 (2019)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM50431068
PNG
(CHEMBL2338796 | US10202399, Example 30 | US9212147...)
Show SMILES Oc1cc(CCc2ccccc2C(F)(F)F)n[nH]c1=O
Show InChI InChI=1S/C13H11F3N2O2/c14-13(15,16)10-4-2-1-3-8(10)5-6-9-7-11(19)12(20)18-17-9/h1-4,7H,5-6H2,(H,17,19)(H,18,20)
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...


US Patent US10202399 (2019)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM50431085
PNG
(CHEMBL2338801 | US10202399, Example 12 | US9212147...)
Show SMILES Oc1cc(CCc2ccc(cc2)C(F)(F)F)n[nH]c1=O
Show InChI InChI=1S/C13H11F3N2O2/c14-13(15,16)9-4-1-8(2-5-9)3-6-10-7-11(19)12(20)18-17-10/h1-2,4-5,7H,3,6H2,(H,17,19)(H,18,20)
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...


US Patent US10202399 (2019)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM50431076
PNG
(CHEMBL2338788 | US10202399, Example 53 | US9212147...)
Show SMILES Oc1cc(CCCc2ccccc2)n[nH]c1=O
Show InChI InChI=1S/C13H14N2O2/c16-12-9-11(14-15-13(12)17)8-4-7-10-5-2-1-3-6-10/h1-3,5-6,9H,4,7-8H2,(H,14,16)(H,15,17)
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...


US Patent US10202399 (2019)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM50431081
PNG
(CHEMBL2338805 | US10202399, Example 23)
Show SMILES COc1cc(CCc2cc(O)c(=O)[nH]n2)cc(OC)c1
Show InChI InChI=1S/C14H16N2O4/c1-19-11-5-9(6-12(8-11)20-2)3-4-10-7-13(17)14(18)16-15-10/h5-8H,3-4H2,1-2H3,(H,15,17)(H,16,18)
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n/an/a 13n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...


US Patent US10202399 (2019)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM196672
PNG
(US10202399, Example 58 | US9212147, 58)
Show SMILES Oc1cc(CCC2CCCCC2)c[nH]c1=O
Show InChI InChI=1S/C13H19NO2/c15-12-8-11(9-14-13(12)16)7-6-10-4-2-1-3-5-10/h8-10,15H,1-7H2,(H,14,16)
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n/an/a 44n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...


US Patent US10202399 (2019)

More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM50431082
PNG
(CHEMBL2338804 | US10202399, Example 19 | US9212147...)
Show SMILES Oc1cc(CCc2cc(cc(c2)C(F)(F)F)C(F)(F)F)n[nH]c1=O
Show InChI InChI=1S/C14H10F6N2O2/c15-13(16,17)8-3-7(4-9(5-8)14(18,19)20)1-2-10-6-11(23)12(24)22-21-10/h3-6H,1-2H2,(H,21,23)(H,22,24)
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n/an/a 63n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...


US Patent US10202399 (2019)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%