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Patent code US10208071

Compile Data Set for Download or QSAR
Found 189 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350513
PNG
((2R)-2-({[(4- bromophenyl)amino]carbonyl}amino)- 3...)
Show SMILES OC(=O)[C@@H](Cc1ccccc1)NC(=O)Nc1ccc(Br)cc1
Show InChI InChI=1S/C16H15BrN2O3/c17-12-6-8-13(9-7-12)18-16(22)19-14(15(20)21)10-11-4-2-1-3-5-11/h1-9,14H,10H2,(H,20,21)(H2,18,19,22)/t14-/m1/s1
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n/an/an/an/a 1.82E+6n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350518
PNG
((2S)-2-({[(4- bromophenyl)amino]carbonyl}amino)- 3...)
Show SMILES CC(C)[C@H](NC(=O)Nc1ccc(Br)cc1)C(O)=O
Show InChI InChI=1S/C12H15BrN2O3/c1-7(2)10(11(16)17)15-12(18)14-9-5-3-8(13)4-6-9/h3-7,10H,1-2H3,(H,16,17)(H2,14,15,18)/t10-/m0/s1
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n/an/an/an/a 7.20E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350539
PNG
(1-(4-bromophenyl)-3-[4-ethyl- 2,5-dioxo-4-(2- phen...)
Show SMILES CCC1(CCc2ccccc2)NC(=O)N(NC(=O)Nc2ccc(Br)cc2)C1=O
Show InChI InChI=1S/C20H21BrN4O3/c1-2-20(13-12-14-6-4-3-5-7-14)17(26)25(19(28)23-20)24-18(27)22-16-10-8-15(21)9-11-16/h3-11H,2,12-13H2,1H3,(H,23,28)(H2,22,24,27)
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n/an/an/an/a 3.00E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350578
PNG
((+) tert-butyl {3-[(3R)-3-(4- cyanophenyl)-7-({[4-...)
Show SMILES CS(=O)c1ccc(NC(=O)Nc2ccc3CC(N(CCCNC(=O)OC(C)(C)C)C(=O)c3c2)c2ccc(cc2)C#N)cc1
Show InChI InChI=1S/C32H35N5O5S/c1-32(2,3)42-31(40)34-16-5-17-37-28(22-8-6-21(20-33)7-9-22)18-23-10-11-25(19-27(23)29(37)38)36-30(39)35-24-12-14-26(15-13-24)43(4)41/h6-15,19,28H,5,16-18H2,1-4H3,(H,34,40)(H2,35,36,39)
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n/an/an/an/a 1.03E+5n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350582
PNG
((+) (2S,3R)-3-[(4-bromophenyl) carbamoyl]spiro[bic...)
Show SMILES OC(=O)C1C2CCC(C1C(=O)Nc1ccc(Br)cc1)C21CC1
Show InChI InChI=1S/C17H18BrNO3/c18-9-1-3-10(4-2-9)19-15(20)13-11-5-6-12(14(13)16(21)22)17(11)7-8-17/h1-4,11-14H,5-8H2,(H,19,20)(H,21,22)
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n/an/an/an/a<1.00E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350515
PNG
((2S,3S)-2-({[(4- bromophenyl)amino]carbonyl}amino)...)
Show SMILES CC[C@H](C)[C@H](NC(=O)Nc1ccc(Br)cc1)C(O)=O
Show InChI InChI=1S/C13H17BrN2O3/c1-3-8(2)11(12(17)18)16-13(19)15-10-6-4-9(14)5-7-10/h4-8,11H,3H2,1-2H3,(H,17,18)(H2,15,16,19)/t8-,11-/m0/s1
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n/an/an/an/a 1.29E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350598
PNG
((2S,3S)-N-(2-amino-2- oxoethyl)-2-{[(4- bromopheny...)
Show SMILES CC[C@H](C)[C@H](NC(=O)Nc1ccc(Br)cc1)C(=O)NCC(N)=O
Show InChI InChI=1S/C15H21BrN4O3/c1-3-9(2)13(14(22)18-8-12(17)21)20-15(23)19-11-6-4-10(16)5-7-11/h4-7,9,13H,3,8H2,1-2H3,(H2,17,21)(H,18,22)(H2,19,20,23)/t9-,13-/m0/s1
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n/an/an/an/a 4.60E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350615
PNG
((2S)-N-(2-amino-2-oxoethyl)- 2-{[(4- bromophenyl)c...)
Show SMILES CC(C)C[C@H](NC(=O)Nc1ccc(Br)cc1)C(=O)NCC(N)=O
Show InChI InChI=1S/C15H21BrN4O3/c1-9(2)7-12(14(22)18-8-13(17)21)20-15(23)19-11-5-3-10(16)4-6-11/h3-6,9,12H,7-8H2,1-2H3,(H2,17,21)(H,18,22)(H2,19,20,23)/t12-/m0/s1
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n/an/an/an/a 1.10E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350619
PNG
((2S)-N-(2-amino-2-oxoethyl)- 2-{[(4-bromo-2- fluor...)
Show SMILES CCC[C@H](NC(=O)Nc1ccc(Br)cc1F)C(=O)NCC(N)=O
Show InChI InChI=1S/C14H18BrFN4O3/c1-2-3-11(13(22)18-7-12(17)21)20-14(23)19-10-5-4-8(15)6-9(10)16/h4-6,11H,2-3,7H2,1H3,(H2,17,21)(H,18,22)(H2,19,20,23)/t11-/m0/s1
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n/an/an/an/a 5.20E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350622
PNG
((2S)-N-(2-amino-2-oxoethyl)- 2-{[(4-bromo-2- fluor...)
Show SMILES CC(C)C[C@H](NC(=O)Nc1ccc(Br)cc1F)C(=O)NCC(N)=O
Show InChI InChI=1S/C15H20BrFN4O3/c1-8(2)5-12(14(23)19-7-13(18)22)21-15(24)20-11-4-3-9(16)6-10(11)17/h3-4,6,8,12H,5,7H2,1-2H3,(H2,18,22)(H,19,23)(H2,20,21,24)/t12-/m0/s1
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n/an/an/an/a 4.50E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350623
PNG
((2S)-2-{[(4-bromo-2- fluorophenyl)carbamoyl]amino}...)
Show SMILES CC(C)C[C@H](NC(=O)Nc1ccc(Br)cc1F)C(=O)NCC(C)=O
Show InChI InChI=1S/C16H21BrFN3O3/c1-9(2)6-14(15(23)19-8-10(3)22)21-16(24)20-13-5-4-11(17)7-12(13)18/h4-5,7,9,14H,6,8H2,1-3H3,(H,19,23)(H2,20,21,24)/t14-/m0/s1
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n/an/an/an/a 2.00E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350628
PNG
((2S)-2-{[(2S)-2-{[(4- bromophenyl)carbamoyl]amino}...)
Show SMILES CC(C)C[C@H](NC(=O)Nc1ccc(Br)cc1)C(=O)N[C@@H](C)C(O)=O
Show InChI InChI=1S/C16H22BrN3O4/c1-9(2)8-13(14(21)18-10(3)15(22)23)20-16(24)19-12-6-4-11(17)5-7-12/h4-7,9-10,13H,8H2,1-3H3,(H,18,21)(H,22,23)(H2,19,20,24)/t10-,13-/m0/s1
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n/an/an/an/a 1.16E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350657
PNG
(US10208071, Compound 119 | diethyl (2-{[(2S)-2-{[(...)
Show SMILES CCOP(=O)(CCNC(=O)[C@H](CC(C)C)NC(=O)Nc1ccc(Br)cc1)OCC
Show InChI InChI=1S/C19H31BrN3O5P/c1-5-27-29(26,28-6-2)12-11-21-18(24)17(13-14(3)4)23-19(25)22-16-9-7-15(20)8-10-16/h7-10,14,17H,5-6,11-13H2,1-4H3,(H,21,24)(H2,22,23,25)/t17-/m0/s1
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n/an/an/an/a 1.61E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350658
PNG
((2S)-2-{[(4- bromophenyl)carbamoyl]amino}- N-[2-(d...)
Show SMILES CC(C)C[C@H](NC(=O)Nc1ccc(Br)cc1)C(=O)NCC(=O)N(C)C
Show InChI InChI=1S/C17H25BrN4O3/c1-11(2)9-14(16(24)19-10-15(23)22(3)4)21-17(25)20-13-7-5-12(18)6-8-13/h5-8,11,14H,9-10H2,1-4H3,(H,19,24)(H2,20,21,25)/t14-/m0/s1
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n/an/an/an/a 1.70E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350661
PNG
(US10208071, Compound 123 | ethyl hydrogen ({[(2S)-...)
Show SMILES CCC[C@H](NC(=O)Nc1ccc(Br)cc1)C(=O)NCP(O)(=O)OCC
Show InChI InChI=1S/C15H23BrN3O5P/c1-3-5-13(14(20)17-10-25(22,23)24-4-2)19-15(21)18-12-8-6-11(16)7-9-12/h6-9,13H,3-5,10H2,1-2H3,(H,17,20)(H,22,23)(H2,18,19,21)/t13-/m0/s1
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n/an/an/an/a 1.00E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350666
PNG
((2S)-4-methyl-2-({[4- (methylsulfanyl)phenyl]carba...)
Show SMILES CSc1ccc(NC(=O)N[C@@H](CC(C)C)C(O)=O)cc1
Show InChI InChI=1S/C14H20N2O3S/c1-9(2)8-12(13(17)18)16-14(19)15-10-4-6-11(20-3)7-5-10/h4-7,9,12H,8H2,1-3H3,(H,17,18)(H2,15,16,19)/t12-/m0/s1
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n/an/an/an/a 1.68E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350670
PNG
(1-(4-bromophenyl)-3-[4- (hydroxymethyl)-2,5-dioxo-...)
Show SMILES CC(C)C1(CO)NC(=O)N(NC(=O)Nc2ccc(Br)cc2)C1=O
Show InChI InChI=1S/C14H17BrN4O4/c1-8(2)14(7-20)11(21)19(13(23)17-14)18-12(22)16-10-5-3-9(15)4-6-10/h3-6,8,20H,7H2,1-2H3,(H,17,23)(H2,16,18,22)
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n/an/an/an/a 1.62E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350672
PNG
(US10208071, Compound 134 | diethyl ({[(2S)-4-methy...)
Show SMILES CCOP(=O)(CNC(=O)[C@H](CC(C)C)NC(=O)Nc1ccc(cc1)C(F)(F)F)OCC
Show InChI InChI=1S/C19H29F3N3O5P/c1-5-29-31(28,30-6-2)12-23-17(26)16(11-13(3)4)25-18(27)24-15-9-7-14(8-10-15)19(20,21)22/h7-10,13,16H,5-6,11-12H2,1-4H3,(H,23,26)(H2,24,25,27)/t16-/m0/s1
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n/an/an/an/a 5.50E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350683
PNG
(2-[2-(1-{[(4-bromo-2- fluorophenyl)carbamoyl]amino...)
Show SMILES CCC1(CCc2ccccc2C(O)=O)NC(=O)N(NC(=O)Nc2ccc(Br)cc2F)C1=O
Show InChI InChI=1S/C21H20BrFN4O5/c1-2-21(10-9-12-5-3-4-6-14(12)17(28)29)18(30)27(20(32)25-21)26-19(31)24-16-8-7-13(22)11-15(16)23/h3-8,11H,2,9-10H2,1H3,(H,25,32)(H,28,29)(H2,24,26,31)
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n/an/an/an/a 1.11E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350689
PNG
(US10208071, Compound 152 | diethyl [2-({[1-{[(4- b...)
Show SMILES CCOP(=O)(CCNC(=O)CC1(NC(=O)N(NC(=O)Nc2ccc(Br)cc2)C1=O)C(C)C)OCC
Show InChI InChI=1S/C21H31BrN5O7P/c1-5-33-35(32,34-6-2)12-11-23-17(28)13-21(14(3)4)18(29)27(20(31)25-21)26-19(30)24-16-9-7-15(22)8-10-16/h7-10,14H,5-6,11-13H2,1-4H3,(H,23,28)(H,25,31)(H2,24,26,30)
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n/an/an/an/a 1.10E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350509
PNG
(3-phenyl-2-[({[4- (trifluoromethoxy)phenyl]amino} ...)
Show SMILES OC(=O)C(Cc1ccccc1)NC(=O)Nc1ccc(OC(F)(F)F)cc1
Show InChI InChI=1S/C17H15F3N2O4/c18-17(19,20)26-13-8-6-12(7-9-13)21-16(25)22-14(15(23)24)10-11-4-2-1-3-5-11/h1-9,14H,10H2,(H,23,24)(H2,21,22,25)
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n/an/an/an/a 1.57E+6n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350512
PNG
((2S)-2-({[(4- bromophenyl)amino]carbonyl}amino)- 3...)
Show SMILES OC(=O)[C@H](Cc1ccccc1)NC(=O)Nc1ccc(Br)cc1
Show InChI InChI=1S/C16H15BrN2O3/c17-12-6-8-13(9-7-12)18-16(22)19-14(15(20)21)10-11-4-2-1-3-5-11/h1-9,14H,10H2,(H,20,21)(H2,18,19,22)/t14-/m0/s1
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n/an/an/an/a 3.10E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350517
PNG
(2-({[(4- bromophenyl)amino]carbonyl}amino)- 3-(1H-...)
Show SMILES OC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)Nc1ccc(Br)cc1
Show InChI InChI=1S/C18H16BrN3O3/c19-12-5-7-13(8-6-12)21-18(25)22-16(17(23)24)9-11-10-20-15-4-2-1-3-14(11)15/h1-8,10,16,20H,9H2,(H,23,24)(H2,21,22,25)
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n/an/an/an/a 6.70E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350519
PNG
((2S)-2-({[(4-bromo-2- fluorophenyl)amino]carbonyl}...)
Show SMILES CC(C)[C@H](NC(=O)Nc1ccc(Br)cc1F)C(O)=O
Show InChI InChI=1S/C12H14BrFN2O3/c1-6(2)10(11(17)18)16-12(19)15-9-4-3-7(13)5-8(9)14/h3-6,10H,1-2H3,(H,17,18)(H2,15,16,19)/t10-/m0/s1
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n/an/an/an/a 1.52E+5n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350532
PNG
(N-(4-bromophenyl)-2-(2,4-dioxo-1,3- diazaspiro[4.6...)
Show SMILES Brc1ccc(NC(=O)CN2C(=O)NC3(CCCCCC3)C2=O)cc1
Show InChI InChI=1S/C17H20BrN3O3/c18-12-5-7-13(8-6-12)19-14(22)11-21-15(23)17(20-16(21)24)9-3-1-2-4-10-17/h5-8H,1-4,9-11H2,(H,19,22)(H,20,24)
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n/an/an/an/a 6.79E+5n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350541
PNG
(US10208071, Compound 3 | {[(2S,3S)-2-{[(4- bromoph...)
Show SMILES CC[C@H](C)[C@H](NC(=O)Nc1ccc(Br)cc1)C(=O)NCC(O)=O
Show InChI InChI=1S/C15H20BrN3O4/c1-3-9(2)13(14(22)17-8-12(20)21)19-15(23)18-11-6-4-10(16)5-7-11/h4-7,9,13H,3,8H2,1-2H3,(H,17,22)(H,20,21)(H2,18,19,23)/t9-,13-/m0/s1
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n/an/an/an/a 1.98E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350545
PNG
(US10208071, Compound 7 | {[(2S)-2-{[(4-bromo-2- fl...)
Show SMILES CC(C)C[C@H](NC(=O)Nc1ccc(Br)cc1F)C(=O)NCC(O)=O
Show InChI InChI=1S/C15H19BrFN3O4/c1-8(2)5-12(14(23)18-7-13(21)22)20-15(24)19-11-4-3-9(16)6-10(11)17/h3-4,6,8,12H,5,7H2,1-2H3,(H,18,23)(H,21,22)(H2,19,20,24)/t12-/m0/s1
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n/an/an/an/a 3.57E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350550
PNG
(3-[(4- bromophenyl)carbamoyl] spiro[bicyclo[2.2.1]...)
Show SMILES OC(=O)C1C2C=CC(C1C(=O)Nc1ccc(Br)cc1)C21CC1
Show InChI InChI=1S/C17H16BrNO3/c18-9-1-3-10(4-2-9)19-15(20)13-11-5-6-12(14(13)16(21)22)17(11)7-8-17/h1-6,11-14H,7-8H2,(H,19,20)(H,21,22)
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n/an/an/an/a 4.00E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350558
PNG
(3-[(4-iodophenyl)carbamoyl]- 7-(propan-2- ylidene)...)
Show SMILES CC(C)=C1C2C=CC1C(C2C(O)=O)C(=O)Nc1ccc(I)cc1
Show InChI InChI=1S/C18H18INO3/c1-9(2)14-12-7-8-13(14)16(18(22)23)15(12)17(21)20-11-5-3-10(19)4-6-11/h3-8,12-13,15-16H,1-2H3,(H,20,21)(H,22,23)
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n/an/an/an/a 1.10E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350581
PNG
(1-[2-(3-aminopropyl)-3-(4- cyanophenyl)-1-oxo-1,2,...)
Show SMILES NCCCN1C(Cc2ccc(NC(=O)Nc3ccc(I)cc3)cc2C1=O)c1ccc(cc1)C#N
Show InChI InChI=1S/C26H24IN5O2/c27-20-7-10-21(11-8-20)30-26(34)31-22-9-6-19-14-24(18-4-2-17(16-29)3-5-18)32(13-1-12-28)25(33)23(19)15-22/h2-11,15,24H,1,12-14,28H2,(H2,30,31,34)
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n/an/an/an/a 1.37E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350592
PNG
(1-(4-bromophenyl)-3-[4- methyl-2,5-dioxo-4-(2- phe...)
Show SMILES CC1(CCc2ccccc2)NC(=O)N(NC(=O)Nc2ccc(Br)cc2)C1=O
Show InChI InChI=1S/C19H19BrN4O3/c1-19(12-11-13-5-3-2-4-6-13)16(25)24(18(27)22-19)23-17(26)21-15-9-7-14(20)8-10-15/h2-10H,11-12H2,1H3,(H,22,27)(H2,21,23,26)
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n/an/an/an/a 5.10E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350593
PNG
(US10208071, Compound 55 | {[(2S)-2-{[(4- bromophen...)
Show SMILES OC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)Nc1ccc(Br)cc1
Show InChI InChI=1S/C18H18BrN3O4/c19-13-6-8-14(9-7-13)21-18(26)22-15(17(25)20-11-16(23)24)10-12-4-2-1-3-5-12/h1-9,15H,10-11H2,(H,20,25)(H,23,24)(H2,21,22,26)/t15-/m0/s1
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n/an/an/an/a 7.70E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350601
PNG
(2S,3S)-2-{[(4- bromophenyl)carbamoyl]amino}- 3-met...)
Show SMILES CC[C@H](C)[C@H](NC(=O)Nc1ccc(Br)cc1)C(=O)NCC(C)=O
Show InChI InChI=1S/C16H22BrN3O3/c1-4-10(2)14(15(22)18-9-11(3)21)20-16(23)19-13-7-5-12(17)6-8-13/h5-8,10,14H,4,9H2,1-3H3,(H,18,22)(H2,19,20,23)/t10-,14-/m0/s1
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n/an/an/an/a 1.05E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350603
PNG
(1-(4-bromophenyl)-3-(4,4- dicyclopropyl-2,5- dioxo...)
Show SMILES Brc1ccc(NC(=O)NN2C(=O)NC(C3CC3)(C3CC3)C2=O)cc1
Show InChI InChI=1S/C16H17BrN4O3/c17-11-5-7-12(8-6-11)18-14(23)20-21-13(22)16(9-1-2-9,10-3-4-10)19-15(21)24/h5-10H,1-4H2,(H,19,24)(H2,18,20,23)
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n/an/an/an/a 1.43E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350609
PNG
((2S)-2-{[(4-bromo-2- fluorophenyl)carbamoyl]amino}...)
Show SMILES OCCNC(=O)[C@H](Cc1ccccc1)NC(=O)Nc1ccc(Br)cc1F
Show InChI InChI=1S/C18H19BrFN3O3/c19-13-6-7-15(14(20)11-13)22-18(26)23-16(17(25)21-8-9-24)10-12-4-2-1-3-5-12/h1-7,11,16,24H,8-10H2,(H,21,25)(H2,22,23,26)/t16-/m0/s1
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n/an/an/an/a 1.56E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350611
PNG
(US10208071, Compound 73 | propan-2-yl {[(2S)-2-{[(...)
Show SMILES CCC[C@H](NC(=O)Nc1ccc(Br)cc1)C(=O)NCC(=O)OC(C)C
Show InChI InChI=1S/C17H24BrN3O4/c1-4-5-14(16(23)19-10-15(22)25-11(2)3)21-17(24)20-13-8-6-12(18)7-9-13/h6-9,11,14H,4-5,10H2,1-3H3,(H,19,23)(H2,20,21,24)/t14-/m0/s1
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n/an/an/an/a 1.45E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350626
PNG
(1-(4-bromophenyl)-3-{4- methyl-2,5-dioxo-4-[2- (th...)
Show SMILES CC1(CCc2cccs2)NC(=O)N(NC(=O)Nc2ccc(Br)cc2)C1=O
Show InChI InChI=1S/C17H17BrN4O3S/c1-17(9-8-13-3-2-10-26-13)14(23)22(16(25)20-17)21-15(24)19-12-6-4-11(18)5-7-12/h2-7,10H,8-9H2,1H3,(H,20,25)(H2,19,21,24)
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n/an/an/an/a 7.90E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350635
PNG
(1-(4-bromophenyl)-3-{4- methyl-4-[2-(5-methylfuran...)
Show SMILES Cc1ccc(CCC2(C)NC(=O)N(NC(=O)Nc3ccc(Br)cc3)C2=O)o1
Show InChI InChI=1S/C18H19BrN4O4/c1-11-3-8-14(27-11)9-10-18(2)15(24)23(17(26)21-18)22-16(25)20-13-6-4-12(19)5-7-13/h3-8H,9-10H2,1-2H3,(H,21,26)(H2,20,22,25)
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n/an/an/an/a 3.50E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350637
PNG
(1-(4-bromophenyl)-3-{4-[2-(3- fluoro-4- hydroxyphe...)
Show SMILES CC1(CCc2ccc(O)c(F)c2)NC(=O)N(NC(=O)Nc2ccc(Br)cc2)C1=O
Show InChI InChI=1S/C19H18BrFN4O4/c1-19(9-8-11-2-7-15(26)14(21)10-11)16(27)25(18(29)23-19)24-17(28)22-13-5-3-12(20)4-6-13/h2-7,10,26H,8-9H2,1H3,(H,23,29)(H2,22,24,28)
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n/an/an/an/a 8.00E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350648
PNG
(2-{[(4- bromophenyl)carbamoyl]amino}- 2,4-dimethyl...)
Show SMILES CC(C)CC(C)(NC(=O)Nc1ccc(Br)cc1)C(O)=O
Show InChI InChI=1S/C14H19BrN2O3/c1-9(2)8-14(3,12(18)19)17-13(20)16-11-6-4-10(15)5-7-11/h4-7,9H,8H2,1-3H3,(H,18,19)(H2,16,17,20)
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n/an/an/an/a 1.94E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350650
PNG
(US10208071, Compound 112 | diethyl ({[(2S)-2-{[(4-...)
Show SMILES CCOP(=O)(CNC(=O)[C@H](CC(C)C)NC(=O)Nc1ccc(Br)cc1)OCC
Show InChI InChI=1S/C18H29BrN3O5P/c1-5-26-28(25,27-6-2)12-20-17(23)16(11-13(3)4)22-18(24)21-15-9-7-14(19)8-10-15/h7-10,13,16H,5-6,11-12H2,1-4H3,(H,20,23)(H2,21,22,24)/t16-/m0/s1
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n/an/an/an/a 480n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350651
PNG
((2-{[(4- bromophenyl)carbamoyl]amino}- 2-ethylbuta...)
Show SMILES CCC(CC)(NC(=O)Nc1ccc(Br)cc1)C(=O)NCC(O)=O
Show InChI InChI=1S/C15H20BrN3O4/c1-3-15(4-2,13(22)17-9-12(20)21)19-14(23)18-11-7-5-10(16)6-8-11/h5-8H,3-4,9H2,1-2H3,(H,17,22)(H,20,21)(H2,18,19,23)
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n/an/an/an/a 1.87E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350653
PNG
(US10208071, Compound 115 | ethyl hydrogen ({[(2S,3...)
Show SMILES CCOP(O)(=O)CNC(=O)[C@@H](NC(=O)Nc1ccc(Br)cc1)[C@@H](C)CC
Show InChI InChI=1S/C16H25BrN3O5P/c1-4-11(3)14(15(21)18-10-26(23,24)25-5-2)20-16(22)19-13-8-6-12(17)7-9-13/h6-9,11,14H,4-5,10H2,1-3H3,(H,18,21)(H,23,24)(H2,19,20,22)/t11-,14-/m0/s1
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n/an/an/an/a 2.70E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350675
PNG
(US10208071, Compound 237 | {[(2S)-4-methyl-2-({[4-...)
Show SMILES CC(C)C[C@H](NC(=O)Nc1ccc(cc1)C(F)(F)F)C(=O)NCS(O)(=O)=O
Show InChI InChI=1S/C15H20F3N3O5S/c1-9(2)7-12(13(22)19-8-27(24,25)26)21-14(23)20-11-5-3-10(4-6-11)15(16,17)18/h3-6,9,12H,7-8H2,1-2H3,(H,19,22)(H2,20,21,23)(H,24,25,26)/t12-/m0/s1
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n/an/an/an/a 1.90E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350684
PNG
(3-({[1-{[(4- bromophenyl)carbamoyl]amino}- 2,5-dio...)
Show SMILES CC(C)C1(CC(=O)NCCC(O)=O)NC(=O)N(NC(=O)Nc2ccc(Br)cc2)C1=O
Show InChI InChI=1S/C18H22BrN5O6/c1-10(2)18(9-13(25)20-8-7-14(26)27)15(28)24(17(30)22-18)23-16(29)21-12-5-3-11(19)4-6-12/h3-6,10H,7-9H2,1-2H3,(H,20,25)(H,22,30)(H,26,27)(H2,21,23,29)
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n/an/an/an/a 3.90E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350686
PNG
(US10208071, Compound 149 | ethyl 3-[1-{[(4- bromop...)
Show SMILES CCOC(=O)CCC1(NC(=O)N(NC(=O)Nc2ccc(Br)cc2)C1=O)C(C)C
Show InChI InChI=1S/C18H23BrN4O5/c1-4-28-14(24)9-10-18(11(2)3)15(25)23(17(27)21-18)22-16(26)20-13-7-5-12(19)6-8-13/h5-8,11H,4,9-10H2,1-3H3,(H,21,27)(H2,20,22,26)
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n/an/an/an/a 6.60E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350520
PNG
(1-(4-chlorophenyl)-3-(2,4-dioxo- 1,3-diazaspiro[4,...)
Show SMILES Clc1ccc(NC(=O)NN2C(=O)NC3(CCCCC3)C2=O)cc1
Show InChI InChI=1S/C15H17ClN4O3/c16-10-4-6-11(7-5-10)17-13(22)19-20-12(21)15(18-14(20)23)8-2-1-3-9-15/h4-7H,1-3,8-9H2,(H,18,23)(H2,17,19,22)
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n/an/an/an/a 4.90E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350529
PNG
(N-(4-bromophenyl)-2-(2,5-dioxo-4,4- dipropylimidaz...)
Show SMILES CCCC1(CCC)NC(=O)N(CC(=O)Nc2ccc(Br)cc2)C1=O
Show InChI InChI=1S/C17H22BrN3O3/c1-3-9-17(10-4-2)15(23)21(16(24)20-17)11-14(22)19-13-7-5-12(18)6-8-13/h5-8H,3-4,9-11H2,1-2H3,(H,19,22)(H,20,24)
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n/an/an/an/a 6.45E+5n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350537
PNG
(N-(4-bromophenyl)-1,3,3a,4,7,7a- hexahydro-1,3-dio...)
Show SMILES Brc1ccc(NC(=O)CN2C(=O)C3C4CC(C=C4)C3C2=O)cc1
Show InChI InChI=1S/C17H15BrN2O3/c18-11-3-5-12(6-4-11)19-13(21)8-20-16(22)14-9-1-2-10(7-9)15(14)17(20)23/h1-6,9-10,14-15H,7-8H2,(H,19,21)
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n/an/an/an/a 5.75E+5n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350540
PNG
(US10208071, Compound 2 | {[(2S)-2-{[(4- bromopheny...)
Show SMILES CCC[C@H](NC(=O)Nc1ccc(Br)cc1)C(=O)NCC(O)=O
Show InChI InChI=1S/C14H18BrN3O4/c1-2-3-11(13(21)16-8-12(19)20)18-14(22)17-10-6-4-9(15)5-7-10/h4-7,11H,2-3,8H2,1H3,(H,16,21)(H,19,20)(H2,17,18,22)/t11-/m0/s1
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n/an/an/an/a 2.00E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350542
PNG
(1-(4-bromophenyl)-3-[4-ethyl- 2,5-dioxo-4-(propan-...)
Show SMILES CCC1(NC(=O)N(NC(=O)Nc2ccc(Br)cc2)C1=O)C(C)C
Show InChI InChI=1S/C15H19BrN4O3/c1-4-15(9(2)3)12(21)20(14(23)18-15)19-13(22)17-11-7-5-10(16)6-8-11/h5-9H,4H2,1-3H3,(H,18,23)(H2,17,19,22)
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n/an/an/an/a 6.70E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350551
PNG
(1-(4-acetylphenyl)-3-{3-(4- cyanophenyl)-2-[2-(1H-...)
Show SMILES CC(=O)c1ccc(NC(=O)Nc2ccc3CC(N(CCc4c[nH]cn4)C(=O)c3c2)c2ccc(cc2)C#N)cc1
Show InChI InChI=1S/C30H26N6O3/c1-19(37)21-6-9-24(10-7-21)34-30(39)35-25-11-8-23-14-28(22-4-2-20(16-31)3-5-22)36(29(38)27(23)15-25)13-12-26-17-32-18-33-26/h2-11,15,17-18,28H,12-14H2,1H3,(H,32,33)(H2,34,35,39)
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n/an/an/an/a 1.10E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350555
PNG
(1-{3-(4-cyanophenyl)-2-[2- (1H-imidazol-4-yl)ethyl...)
Show SMILES CSc1ccc(NC(=O)Nc2ccc3CC(N(CCc4c[nH]cn4)C(=O)c3c2)c2ccc(cc2)C#N)cc1
Show InChI InChI=1S/C29H26N6O2S/c1-38-25-10-8-22(9-11-25)33-29(37)34-23-7-6-21-14-27(20-4-2-19(16-30)3-5-20)35(28(36)26(21)15-23)13-12-24-17-31-18-32-24/h2-11,15,17-18,27H,12-14H2,1H3,(H,31,32)(H2,33,34,37)
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n/an/an/an/a 5.50E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350562
PNG
(1-{3-(5-fluoropyridin-2-yl)-2- [2-(1H-imidazol-4-y...)
Show SMILES CS(=O)c1ccc(NC(=O)Nc2ccc3CC(N(CCc4c[nH]cn4)C(=O)c3c2)c2ccc(F)cn2)cc1
Show InChI InChI=1S/C27H25FN6O3S/c1-38(37)22-7-5-19(6-8-22)32-27(36)33-20-4-2-17-12-25(24-9-3-18(28)14-30-24)34(26(35)23(17)13-20)11-10-21-15-29-16-31-21/h2-9,13-16,25H,10-12H2,1H3,(H,29,31)(H2,32,33,36)
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n/an/an/an/a 1.18E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350571
PNG
(1-{3-(5-chloropyridin-2-yl)-2- [2-(1H-imidazol-4-y...)
Show SMILES CS(=O)(=O)c1ccc(NC(=O)Nc2ccc3CC(N(CCc4c[nH]cn4)C(=O)c3c2)c2ccc(Cl)cn2)cc1
Show InChI InChI=1S/C27H25ClN6O4S/c1-39(37,38)22-7-5-19(6-8-22)32-27(36)33-20-4-2-17-12-25(24-9-3-18(28)14-30-24)34(26(35)23(17)13-20)11-10-21-15-29-16-31-21/h2-9,13-16,25H,10-12H2,1H3,(H,29,31)(H2,32,33,36)
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n/an/an/an/a 9.50E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350577
PNG
(N-(4-iodophenyl) spiro[bicyclo[2.2.1]heptane- 7,1'...)
Show SMILES NC(=O)C1C2C=CC(C1C(=O)Nc1ccc(I)cc1)C21CC1
Show InChI InChI=1S/C17H17IN2O2/c18-9-1-3-10(4-2-9)20-16(22)14-12-6-5-11(13(14)15(19)21)17(12)7-8-17/h1-6,11-14H,7-8H2,(H2,19,21)(H,20,22)
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n/an/an/an/a 1.60E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350604
PNG
((+)1-(4-bromophenyl)-3-[4- ethyl-2,5-dioxo-4-(prop...)
Show SMILES CCC1(NC(=O)N(NC(=O)Nc2ccc(Br)cc2)C1=O)C(C)C
Show InChI InChI=1S/C15H19BrN4O3/c1-4-15(9(2)3)12(21)20(14(23)18-15)19-13(22)17-11-7-5-10(16)6-8-11/h5-9H,4H2,1-3H3,(H,18,23)(H2,17,19,22)
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n/an/an/an/a 4.30E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350608
PNG
((2S)-2-{[(4- bromophenyl)carbamoyl]amino} pentanoi...)
Show SMILES CCC[C@H](NC(=O)Nc1ccc(Br)cc1)C(O)=O
Show InChI InChI=1S/C12H15BrN2O3/c1-2-3-10(11(16)17)15-12(18)14-9-6-4-8(13)5-7-9/h4-7,10H,2-3H2,1H3,(H,16,17)(H2,14,15,18)/t10-/m0/s1
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n/an/an/an/a 7.10E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350612
PNG
(US10208071, Compound 74 | {[(2S)-2-+{[(4-bromo-2- ...)
Show SMILES CCC[C@H](NC(=O)Nc1ccc(Br)cc1F)C(=O)NCC(O)=O
Show InChI InChI=1S/C14H17BrFN3O4/c1-2-3-11(13(22)17-7-12(20)21)19-14(23)18-10-5-4-8(15)6-9(10)16/h4-6,11H,2-3,7H2,1H3,(H,17,22)(H,20,21)(H2,18,19,23)/t11-/m0/s1
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n/an/an/an/a 4.10E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350614
PNG
(1-(4-bromophenyl)-3-{4-[2- (furan-2-yl)ethyl]-4-me...)
Show SMILES CC1(CCc2ccco2)NC(=O)N(NC(=O)Nc2ccc(Br)cc2)C1=O
Show InChI InChI=1S/C17H17BrN4O4/c1-17(9-8-13-3-2-10-26-13)14(23)22(16(25)20-17)21-15(24)19-12-6-4-11(18)5-7-12/h2-7,10H,8-9H2,1H3,(H,20,25)(H2,19,21,24)
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n/an/an/an/a 5.20E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350627
PNG
(1-(4-bromo-2-fluorophenyl)- 3-{4-[2-(4- hydroxyphe...)
Show SMILES CC1(CCc2ccc(O)cc2)NC(=O)N(NC(=O)Nc2ccc(Br)cc2F)C1=O
Show InChI InChI=1S/C19H18BrFN4O4/c1-19(9-8-11-2-5-13(26)6-3-11)16(27)25(18(29)23-19)24-17(28)22-15-7-4-12(20)10-14(15)21/h2-7,10,26H,8-9H2,1H3,(H,23,29)(H2,22,24,28)
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n/an/an/an/a 8.70E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350634
PNG
((2S)-2-{[(4- bromophenyl)carbamoyl]amino}- N-[(2R)...)
Show SMILES CC(C)C[C@H](NC(=O)Nc1ccc(Br)cc1)C(=O)N[C@H](C)CO
Show InChI InChI=1S/C16H24BrN3O3/c1-10(2)8-14(15(22)18-11(3)9-21)20-16(23)19-13-6-4-12(17)5-7-13/h4-7,10-11,14,21H,8-9H2,1-3H3,(H,18,22)(H2,19,20,23)/t11-,14+/m1/s1
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n/an/an/an/a 3.00E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350642
PNG
((2S)-2-{[(4- bromophenyl)carbamoyl]amino}- 4-methy...)
Show SMILES CC(C)C[C@H](NC(=O)Nc1ccc(Br)cc1)C(=O)NCc1nnn[nH]1
Show InChI InChI=1S/C15H20BrN7O2/c1-9(2)7-12(14(24)17-8-13-20-22-23-21-13)19-15(25)18-11-5-3-10(16)4-6-11/h3-6,9,12H,7-8H2,1-2H3,(H,17,24)(H2,18,19,25)(H,20,21,22,23)/t12-/m0/s1
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n/an/an/an/a 2.30E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350646
PNG
(1-(4-bromophenyl)-3-{4-[2-(3- hydroxyphenyl)ethyl]...)
Show SMILES CC1(CCc2cccc(O)c2)NC(=O)N(NC(=O)Nc2ccc(Br)cc2)C1=O
Show InChI InChI=1S/C19H19BrN4O4/c1-19(10-9-12-3-2-4-15(25)11-12)16(26)24(18(28)22-19)23-17(27)21-14-7-5-13(20)6-8-14/h2-8,11,25H,9-10H2,1H3,(H,22,28)(H2,21,23,27)
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n/an/an/an/a 2.10E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350649
PNG
(US10208071, Compound 111 | [(2-{[(4- bromophenyl)c...)
Show SMILES CC(C)CC(C)(NC(=O)Nc1ccc(Br)cc1)C(=O)NCC(O)=O
Show InChI InChI=1S/C16H22BrN3O4/c1-10(2)8-16(3,14(23)18-9-13(21)22)20-15(24)19-12-6-4-11(17)5-7-12/h4-7,10H,8-9H2,1-3H3,(H,18,23)(H,21,22)(H2,19,20,24)
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n/an/an/an/a 1.91E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350652
PNG
(US10208071, Compound 114 | diethyl ({[(2S,3S)-2-{[...)
Show SMILES CCOP(=O)(CNC(=O)[C@@H](NC(=O)Nc1ccc(Br)cc1)[C@@H](C)CC)OCC
Show InChI InChI=1S/C18H29BrN3O5P/c1-5-13(4)16(17(23)20-12-28(25,26-6-2)27-7-3)22-18(24)21-15-10-8-14(19)9-11-15/h8-11,13,16H,5-7,12H2,1-4H3,(H,20,23)(H2,21,22,24)/t13-,16-/m0/s1
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n/an/an/an/a 2.90E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350665
PNG
(US10208071, Compound 127 | {[(2S)-2-{[(4- bromophe...)
Show SMILES CC(C)C[C@H](NC(=O)Nc1ccc(Br)cc1)C(=O)NCS(O)(=O)=O
Show InChI InChI=1S/C14H20BrN3O5S/c1-9(2)7-12(13(19)16-8-24(21,22)23)18-14(20)17-11-5-3-10(15)4-6-11/h3-6,9,12H,7-8H2,1-2H3,(H,16,19)(H2,17,18,20)(H,21,22,23)/t12-/m0/s1
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n/an/an/an/a 2.00E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350680
PNG
(2-[2-(1-{[(4- bromophenyl)carbamoyl]amino}- 4-ethy...)
Show SMILES CCC1(CCc2ccccc2C(O)=O)NC(=O)N(NC(=O)Nc2ccc(Br)cc2)C1=O
Show InChI InChI=1S/C21H21BrN4O5/c1-2-21(12-11-13-5-3-4-6-16(13)17(27)28)18(29)26(20(31)24-21)25-19(30)23-15-9-7-14(22)8-10-15/h3-10H,2,11-12H2,1H3,(H,24,31)(H,27,28)(H2,23,25,30)
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n/an/an/an/a 1.72E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350682
PNG
(3-({[-{[(4-bromo-2- fluorophenyl)carbamoyl]amino}-...)
Show SMILES CC(C)C1(CC(=O)NCCC(O)=O)NC(=O)N(NC(=O)Nc2ccc(Br)cc2F)C1=O
Show InChI InChI=1S/C18H21BrFN5O6/c1-9(2)18(8-13(26)21-6-5-14(27)28)15(29)25(17(31)23-18)24-16(30)22-12-4-3-10(19)7-11(12)20/h3-4,7,9H,5-6,8H2,1-2H3,(H,21,26)(H,23,31)(H,27,28)(H2,22,24,30)
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n/an/an/an/a 1.00E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350690
PNG
(US10208071, Compound 153 | ethyl 3-{[(4- bromophen...)
Show SMILES CCOC(=O)C1CCC2(CC1)NC(=O)N(NC(=O)Nc1ccc(Br)cc1)C2=O
Show InChI InChI=1S/C18H21BrN4O5/c1-2-28-14(24)11-7-9-18(10-8-11)15(25)23(17(27)21-18)22-16(26)20-13-5-3-12(19)4-6-13/h3-6,11H,2,7-10H2,1H3,(H,21,27)(H2,20,22,26)
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n/an/an/an/a 1.20E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350691
PNG
(US10208071, Compound 154 | tert-butyl {[(2S)-2-{[(...)
Show SMILES CC(C)C[C@H](NC(=O)Nc1ccc(Br)cc1)C(=O)N(C)CC(=O)OC(C)(C)C
Show InChI InChI=1S/C20H30BrN3O4/c1-13(2)11-16(18(26)24(6)12-17(25)28-20(3,4)5)23-19(27)22-15-9-7-14(21)8-10-15/h7-10,13,16H,11-12H2,1-6H3,(H2,22,23,27)/t16-/m0/s1
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n/an/an/an/a 1.20E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350471
PNG
(2-({[(4- chlorophenyl)amino]carbonyl}amino)- 3-phe...)
Show SMILES OC(=O)C(Cc1ccccc1)NC(=O)Nc1ccc(Cl)cc1
Show InChI InChI=1S/C16H15ClN2O3/c17-12-6-8-13(9-7-12)18-16(22)19-14(15(20)21)10-11-4-2-1-3-5-11/h1-9,14H,10H2,(H,20,21)(H2,18,19,22)
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n/an/an/an/a 1.10E+5n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350510
PNG
(2-({[(3,4- dimethoxyphenyl)amino]carbonyl} amino)-...)
Show SMILES COc1ccc(NC(=O)NC(Cc2ccccc2)C(O)=O)cc1OC
Show InChI InChI=1S/C18H20N2O5/c1-24-15-9-8-13(11-16(15)25-2)19-18(23)20-14(17(21)22)10-12-6-4-3-5-7-12/h3-9,11,14H,10H2,1-2H3,(H,21,22)(H2,19,20,23)
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n/an/an/an/a 2.79E+6n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350511
PNG
(US10208071, Compound 51 | US10208071, Table 1.8 | ...)
Show SMILES OC(=O)[C@H](Cc1ccccc1)NC(=O)Nc1ccc(I)cc1
Show InChI InChI=1S/C16H15IN2O3/c17-12-6-8-13(9-7-12)18-16(22)19-14(15(20)21)10-11-4-2-1-3-5-11/h1-9,14H,10H2,(H,20,21)(H2,18,19,22)/t14-/m0/s1
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n/an/an/an/a 1.43E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350547
PNG
((2S)-2-{[(4- bromophenyl)carbamoyl]amino}-4- methy...)
Show SMILES CC(C)C[C@H](NC(=O)Nc1ccc(Br)cc1)C(O)=O
Show InChI InChI=1S/C13H17BrN2O3/c1-8(2)7-11(12(17)18)16-13(19)15-10-5-3-9(14)4-6-10/h3-6,8,11H,7H2,1-2H3,(H,17,18)(H2,15,16,19)/t11-/m0/s1
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n/an/an/an/a 5.95E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350549
PNG
(3-[(4- iodophenyl)carbamoyl] spiro[bicyclo[2.2.1]h...)
Show SMILES OC(=O)C1C2C=CC(C1C(=O)Nc1ccc(I)cc1)C21CC1
Show InChI InChI=1S/C17H16INO3/c18-9-1-3-10(4-2-9)19-15(20)13-11-5-6-12(14(13)16(21)22)17(11)7-8-17/h1-6,11-14H,7-8H2,(H,19,20)(H,21,22)
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n/an/an/an/a 1.60E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350553
PNG
(3-[(4- iodophenyl)carbamoyl] spiro[bicyclo[2.2.1]h...)
Show SMILES OC(=O)C1C2CCC(C1C(=O)Nc1ccc(I)cc1)C21CC1
Show InChI InChI=1S/C17H18INO3/c18-9-1-3-10(4-2-9)19-15(20)13-11-5-6-12(14(13)16(21)22)17(11)7-8-17/h1-4,11-14H,5-8H2,(H,19,20)(H,21,22)
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n/an/an/an/a 600n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350556
PNG
(1-[2-(3-aminopropyl)-3-(4- cyanophenyl)-1-oxo-1,2,...)
Show SMILES CS(=O)(=O)c1ccc(NC(=O)Nc2ccc3CC(N(CCCN)C(=O)c3c2)c2ccc(cc2)C#N)cc1
Show InChI InChI=1S/C27H27N5O4S/c1-37(35,36)23-11-9-21(10-12-23)30-27(34)31-22-8-7-20-15-25(19-5-3-18(17-29)4-6-19)32(14-2-13-28)26(33)24(20)16-22/h3-12,16,25H,2,13-15,28H2,1H3,(H2,30,31,34)
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n/an/an/an/a 1.00E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350568
PNG
(N-(4-bromophenyl) spiro[bicyclo[2.2.1]heptane- 7,1...)
Show SMILES NC(=O)C1C2CCC(C1C(=O)Nc1ccc(Br)cc1)C21CC1
Show InChI InChI=1S/C17H19BrN2O2/c18-9-1-3-10(4-2-9)20-16(22)14-12-6-5-11(13(14)15(19)21)17(12)7-8-17/h1-4,11-14H,5-8H2,(H2,19,21)(H,20,22)
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n/an/an/an/a 2.50E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350585
PNG
(N-(4-bromophenyl)-N'- ethylspiro[bicyclo[2.2.1]hep...)
Show SMILES CCNC(=O)C1C2CCC(C1C(=O)Nc1ccc(Br)cc1)C21CC1
Show InChI InChI=1S/C19H23BrN2O2/c1-2-21-17(23)15-13-7-8-14(19(13)9-10-19)16(15)18(24)22-12-5-3-11(20)4-6-12/h3-6,13-16H,2,7-10H2,1H3,(H,21,23)(H,22,24)
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n/an/an/an/a 9.30E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350588
PNG
(1-(4-bromo-2-fluorophenyl)- 3-(4,4-diethyl-2,5- di...)
Show SMILES CCC1(CC)NC(=O)N(NC(=O)Nc2ccc(Br)cc2F)C1=O
Show InChI InChI=1S/C14H16BrFN4O3/c1-3-14(4-2)11(21)20(13(23)18-14)19-12(22)17-10-6-5-8(15)7-9(10)16/h5-7H,3-4H2,1-2H3,(H,18,23)(H2,17,19,22)
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n/an/an/an/a 1.57E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350511
PNG
(US10208071, Compound 51 | US10208071, Table 1.8 | ...)
Show SMILES OC(=O)[C@H](Cc1ccccc1)NC(=O)Nc1ccc(I)cc1
Show InChI InChI=1S/C16H15IN2O3/c17-12-6-8-13(9-7-12)18-16(22)19-14(15(20)21)10-11-4-2-1-3-5-11/h1-9,14H,10H2,(H,20,21)(H2,18,19,22)/t14-/m0/s1
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n/an/an/an/a 1.45E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350596
PNG
((2S)-2-{[(4- bromophenyl)carbamoyl]amino}- N-(2-hy...)
Show SMILES OCCNC(=O)[C@H](Cc1ccccc1)NC(=O)Nc1ccc(Br)cc1
Show InChI InChI=1S/C18H20BrN3O3/c19-14-6-8-15(9-7-14)21-18(25)22-16(17(24)20-10-11-23)12-13-4-2-1-3-5-13/h1-9,16,23H,10-12H2,(H,20,24)(H2,21,22,25)/t16-/m0/s1
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n/an/an/an/a 7.00E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350597
PNG
(US10208071, Compound 59 | {[(2S,3S)-2-{[(4-bromo-2...)
Show SMILES CC[C@H](C)[C@H](NC(=O)Nc1ccc(Br)cc1F)C(=O)NCC(O)=O
Show InChI InChI=1S/C15H19BrFN3O4/c1-3-8(2)13(14(23)18-7-12(21)22)20-15(24)19-11-5-4-9(16)6-10(11)17/h4-6,8,13H,3,7H2,1-2H3,(H,18,23)(H,21,22)(H2,19,20,24)/t8-,13-/m0/s1
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n/an/an/an/a 5.50E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350602
PNG
(1-(4-bromophenyl)-3-[2,5- dioxo-4,4-di(propan-2- y...)
Show SMILES CC(C)C1(NC(=O)N(NC(=O)Nc2ccc(Br)cc2)C1=O)C(C)C
Show InChI InChI=1S/C16H21BrN4O3/c1-9(2)16(10(3)4)13(22)21(15(24)19-16)20-14(23)18-12-7-5-11(17)6-8-12/h5-10H,1-4H3,(H,19,24)(H2,18,20,23)
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n/an/an/an/a 3.80E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350605
PNG
((-)1-(4-bromophenyl)-3-[4- ethyl-2,5-dioxo-4-(prop...)
Show SMILES CCC1(NC(=O)N(NC(=O)Nc2ccc(Br)cc2)C1=O)C(C)C
Show InChI InChI=1S/C15H19BrN4O3/c1-4-15(9(2)3)12(21)20(14(23)18-15)19-13(22)17-11-7-5-10(16)6-8-11/h5-9H,4H2,1-3H3,(H,18,23)(H2,17,19,22)
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n/an/an/an/a 3.30E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350616
PNG
((2S)-2-{[(4- bromophenyl)carbamoyl]amino}- 4-methy...)
Show SMILES CC(C)C[C@H](NC(=O)Nc1ccc(Br)cc1)C(=O)NCC(C)=O
Show InChI InChI=1S/C16H22BrN3O3/c1-10(2)8-14(15(22)18-9-11(3)21)20-16(23)19-13-6-4-12(17)5-7-13/h4-7,10,14H,8-9H2,1-3H3,(H,18,22)(H2,19,20,23)/t14-/m0/s1
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n/an/an/an/a 4.70E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350624
PNG
(1-(4-bromophenyl)-3-{-[2-(4- hydroxyphenyl)ethyl]-...)
Show SMILES CC1(CCc2ccc(O)cc2)NC(=O)N(NC(=O)Nc2ccc(Br)cc2)C1=O
Show InChI InChI=1S/C19H19BrN4O4/c1-19(11-10-12-2-8-15(25)9-3-12)16(26)24(18(28)22-19)23-17(27)21-14-6-4-13(20)5-7-14/h2-9,25H,10-11H2,1H3,(H,22,28)(H2,21,23,27)
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n/an/an/an/a 1.33E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350636
PNG
(1-(4-bromo-2-fluorophenyl)- 3-{4-[2-(3-fluoro-4- h...)
Show SMILES CC1(CCc2ccc(O)c(F)c2)NC(=O)N(NC(=O)Nc2ccc(Br)cc2F)C1=O
Show InChI InChI=1S/C19H17BrF2N4O4/c1-19(7-6-10-2-5-15(27)13(22)8-10)16(28)26(18(30)24-19)25-17(29)23-14-4-3-11(20)9-12(14)21/h2-5,8-9,27H,6-7H2,1H3,(H,24,30)(H2,23,25,29)
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n/an/an/an/a 7.40E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350645
PNG
(1-(4-bromo-2-fluorophenyl)- 3-{4-[2-(3- hydroxyphe...)
Show SMILES CC1(CCc2cccc(O)c2)NC(=O)N(NC(=O)Nc2ccc(Br)cc2F)C1=O
Show InChI InChI=1S/C19H18BrFN4O4/c1-19(8-7-11-3-2-4-13(26)9-11)16(27)25(18(29)23-19)24-17(28)22-15-6-5-12(20)10-14(15)21/h2-6,9-10,26H,7-8H2,1H3,(H,23,29)(H2,22,24,28)
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n/an/an/an/a 2.20E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350647
PNG
(1-(4-bromophenyl)-3-{4-[2-(2- hydroxyphenyl)ethyl]...)
Show SMILES CC1(CCc2ccccc2O)NC(=O)N(NC(=O)Nc2ccc(Br)cc2)C1=O
Show InChI InChI=1S/C19H19BrN4O4/c1-19(11-10-12-4-2-3-5-15(12)25)16(26)24(18(28)22-19)23-17(27)21-14-8-6-13(20)7-9-14/h2-9,25H,10-11H2,1H3,(H,22,28)(H2,21,23,27)
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n/an/an/an/a 970n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350667
PNG
(US10208071, Compound 129 | propan-2-yl hydrogen {[...)
Show SMILES CC(C)C[C@H](NC(=O)Nc1ccc(Br)cc1)C(=O)NCP(O)(=O)OC(C)C
Show InChI InChI=1S/C17H27BrN3O5P/c1-11(2)9-15(16(22)19-10-27(24,25)26-12(3)4)21-17(23)20-14-7-5-13(18)6-8-14/h5-8,11-12,15H,9-10H2,1-4H3,(H,19,22)(H,24,25)(H2,20,21,23)/t15-/m0/s1
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n/an/an/an/a 1.87E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350669
PNG
(US10208071, Compound 131 | dipropan-2-yl ({[(2S)-2...)
Show SMILES CC(C)C[C@H](NC(=O)Nc1ccc(Br)cc1)C(=O)NCP(=O)(OC(C)C)OC(C)C
Show InChI InChI=1S/C20H33BrN3O5P/c1-13(2)11-18(24-20(26)23-17-9-7-16(21)8-10-17)19(25)22-12-30(27,28-14(3)4)29-15(5)6/h7-10,13-15,18H,11-12H2,1-6H3,(H,22,25)(H2,23,24,26)/t18-/m0/s1
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n/an/an/an/a 4.00E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350508
PNG
((2S)-2-({[(4- nitrophenyl)amino]carbonyl}amino)- 3...)
Show SMILES OC(=O)C(Cc1ccccc1)NC(=O)Nc1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C16H15N3O5/c20-15(21)14(10-11-4-2-1-3-5-11)18-16(22)17-12-6-8-13(9-7-12)19(23)24/h1-9,14H,10H2,(H,20,21)(H2,17,18,22)
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n/an/an/an/a 5.74E+5n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350514
PNG
(3-phenyl-2-{[(pyridin-3- ylamino)carbonyl]amino}pr...)
Show SMILES OC(=O)C(Cc1ccccc1)NC(=O)Nc1cccnc1
Show InChI InChI=1S/C15H15N3O3/c19-14(20)13(9-11-5-2-1-3-6-11)18-15(21)17-12-7-4-8-16-10-12/h1-8,10,13H,9H2,(H,19,20)(H2,17,18,21)
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n/an/an/an/a>1.00E+7n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350516
PNG
((2S)-({[(4- bromophenyl)amino]carbonyl}amino) (phe...)
Show SMILES OC(=O)[C@@H](NC(=O)Nc1ccc(Br)cc1)c1ccccc1
Show InChI InChI=1S/C15H13BrN2O3/c16-11-6-8-12(9-7-11)17-15(21)18-13(14(19)20)10-4-2-1-3-5-10/h1-9,13H,(H,19,20)(H2,17,18,21)/t13-/m0/s1
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n/an/an/an/a 2.58E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350524
PNG
(1-(2-fluorophenyl)-3-[4-methyl- 2,5-dioxo-4-(2- ph...)
Show SMILES CC1(CCc2ccccc2)NC(=O)N(NC(=O)Nc2ccccc2F)C1=O
Show InChI InChI=1S/C19H19FN4O3/c1-19(12-11-13-7-3-2-4-8-13)16(25)24(18(27)22-19)23-17(26)21-15-10-6-5-9-14(15)20/h2-10H,11-12H2,1H3,(H,22,27)(H2,21,23,26)
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n/an/an/an/a 2.58E+5n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350525
PNG
(N-(4-bromophenyl)-2-(4,4-dimethyl- 2,5-dioxoimidaz...)
Show SMILES CC1(C)NC(=O)N(CC(=O)Nc2ccc(Br)cc2)C1=O
Show InChI InChI=1S/C13H14BrN3O3/c1-13(2)11(19)17(12(20)16-13)7-10(18)15-9-5-3-8(14)4-6-9/h3-6H,7H2,1-2H3,(H,15,18)(H,16,20)
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n/an/an/an/a 7.19E+5n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350538
PNG
(N-(4-bromophenyl)-1,3,3a,4,7,7a- hexahydro-1,3-dio...)
Show SMILES Brc1ccc(NC(=O)CN2C(=O)C3CC=CCC3C2=O)cc1
Show InChI InChI=1S/C16H15BrN2O3/c17-10-5-7-11(8-6-10)18-14(20)9-19-15(21)12-3-1-2-4-13(12)16(19)22/h1-2,5-8,12-13H,3-4,9H2,(H,18,20)
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n/an/an/an/a 3.95E+5n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350544
PNG
(2-{[(2S)-2-{[(4- bromophenyl)carbamoyl] amino}-4- ...)
Show SMILES CC(C)C[C@H](NC(=O)Nc1ccc(Br)cc1)C(=O)NC(C)(C)C(O)=O
Show InChI InChI=1S/C17H24BrN3O4/c1-10(2)9-13(14(22)21-17(3,4)15(23)24)20-16(25)19-12-7-5-11(18)6-8-12/h5-8,10,13H,9H2,1-4H3,(H,21,22)(H,23,24)(H2,19,20,25)/t13-/m0/s1
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n/an/an/an/a 1.66E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350557
PNG
(1-{3-(4-cyanophenyl)-2-[2- (1H-imidazol-4-yl)ethyl...)
Show SMILES CS(=O)(=O)c1ccc(NC(=O)Nc2ccc3CC(N(CCc4c[nH]cn4)C(=O)c3c2)c2ccc(cc2)C#N)cc1
Show InChI InChI=1S/C29H26N6O4S/c1-40(38,39)25-10-8-22(9-11-25)33-29(37)34-23-7-6-21-14-27(20-4-2-19(16-30)3-5-20)35(28(36)26(21)15-23)13-12-24-17-31-18-32-24/h2-11,15,17-18,27H,12-14H2,1H3,(H,31,32)(H2,33,34,37)
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n/an/an/an/a 2.00E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350565
PNG
(1-{3-(5-chlorofuran-2-yl)-2-[2- (1H-imidazol-4-yl)...)
Show SMILES CSc1ccc(NC(=O)Nc2ccc3CC(N(CCc4c[nH]cn4)C(=O)c3c2)c2ccc(Cl)o2)cc1
Show InChI InChI=1S/C26H24ClN5O3S/c1-36-20-6-4-17(5-7-20)30-26(34)31-18-3-2-16-12-22(23-8-9-24(27)35-23)32(25(33)21(16)13-18)11-10-19-14-28-15-29-19/h2-9,13-15,22H,10-12H2,1H3,(H,28,29)(H2,30,31,34)
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n/an/an/an/a 1.70E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350566
PNG
(1-{3-(6-chloropyridin-3-yl)-2- [2-(1H-imidazol-4-y...)
Show SMILES CSc1ccc(NC(=O)Nc2ccc3CC(N(CCc4c[nH]cn4)C(=O)c3c2)c2ccc(Cl)nc2)cc1
Show InChI InChI=1S/C27H25ClN6O2S/c1-37-22-7-5-19(6-8-22)32-27(36)33-20-4-2-17-12-24(18-3-9-25(28)30-14-18)34(26(35)23(17)13-20)11-10-21-15-29-16-31-21/h2-9,13-16,24H,10-12H2,1H3,(H,29,31)(H2,32,33,36)
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n/an/an/an/a 6.30E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350572
PNG
(N-(4-bromophenyl)-7,7- dimethylbicyclo[2.2.1]hepta...)
Show SMILES CC1(C)C2CCC1C(C2C(N)=O)C(=O)Nc1ccc(Br)cc1
Show InChI InChI=1S/C17H21BrN2O2/c1-17(2)11-7-8-12(17)14(13(11)15(19)21)16(22)20-10-5-3-9(18)4-6-10/h3-6,11-14H,7-8H2,1-2H3,(H2,19,21)(H,20,22)
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n/an/an/an/a 1.50E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350573
PNG
(N-(4-iodophenyl)-7,7- dimethylbicyclo[2.2.1]heptan...)
Show SMILES CC1(C)C2CCC1C(C2C(N)=O)C(=O)Nc1ccc(I)cc1
Show InChI InChI=1S/C17H21IN2O2/c1-17(2)11-7-8-12(17)14(13(11)15(19)21)16(22)20-10-5-3-9(18)4-6-10/h3-6,11-14H,7-8H2,1-2H3,(H2,19,21)(H,20,22)
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n/an/an/an/a 2.60E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350576
PNG
(N-(4-iodophenyl) spiro[bicyclo[2.2.1]heptane- 7,1'...)
Show SMILES NC(=O)C1C2CCC(C1C(=O)Nc1ccc(I)cc1)C21CC1
Show InChI InChI=1S/C17H19IN2O2/c18-9-1-3-10(4-2-9)20-16(22)14-12-6-5-11(13(14)15(19)21)17(12)7-8-17/h1-4,11-14H,5-8H2,(H2,19,21)(H,20,22)
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n/an/an/an/a 1.90E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350579
PNG
((+) 1-[(3R)-2-(3- aminopropyl)-3-(4- cyanophenyl)-...)
Show SMILES CS(=O)c1ccc(NC(=O)Nc2ccc3CC(N(CCCN)C(=O)c3c2)c2ccc(cc2)C#N)cc1
Show InChI InChI=1S/C27H27N5O3S/c1-36(35)23-11-9-21(10-12-23)30-27(34)31-22-8-7-20-15-25(19-5-3-18(17-29)4-6-19)32(14-2-13-28)26(33)24(20)16-22/h3-12,16,25H,2,13-15,28H2,1H3,(H2,30,31,34)
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n/an/an/an/a 1.06E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350580
PNG
(1-[2-(3-aminopropyl)-3- methyl-1-oxo-1,2,3,4- tetr...)
Show SMILES CSc1ccc(NC(=O)Nc2ccc3CC(C)N(CCCN)C(=O)c3c2)cc1
Show InChI InChI=1S/C21H26N4O2S/c1-14-12-15-4-5-17(13-19(15)20(26)25(14)11-3-10-22)24-21(27)23-16-6-8-18(28-2)9-7-16/h4-9,13-14H,3,10-12,22H2,1-2H3,(H2,23,24,27)
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n/an/an/an/a 1.50E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350586
PNG
(N-(4-bromophenyl)-N'- (propan-2- yl)spiro[bicyclo[...)
Show SMILES CC(C)NC(=O)C1C2CCC(C1C(=O)Nc1ccc(Br)cc1)C21CC1
Show InChI InChI=1S/C20H25BrN2O2/c1-11(2)22-18(24)16-14-7-8-15(20(14)9-10-20)17(16)19(25)23-13-5-3-12(21)4-6-13/h3-6,11,14-17H,7-10H2,1-2H3,(H,22,24)(H,23,25)
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n/an/an/an/a 6.70E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350590
PNG
(1-(4-bromophenyl)-3-(2,4- dioxo-1,3-diazaspiro[4.5...)
Show SMILES Brc1ccc(NC(=O)NN2C(=O)NC3(CCCCC3)C2=O)cc1
Show InChI InChI=1S/C15H17BrN4O3/c16-10-4-6-11(7-5-10)17-13(22)19-20-12(21)15(18-14(20)23)8-2-1-3-9-15/h4-7H,1-3,8-9H2,(H,18,23)(H2,17,19,22)
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n/an/an/an/a 1.51E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350606
PNG
((2S)-2-{[(4-bromo-2- fluorophenyl)carbamoyl]amino}...)
Show SMILES CC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)Nc1ccc(Br)cc1F
Show InChI InChI=1S/C19H19BrFN3O3/c1-12(25)11-22-18(26)17(9-13-5-3-2-4-6-13)24-19(27)23-16-8-7-14(20)10-15(16)21/h2-8,10,17H,9,11H2,1H3,(H,22,26)(H2,23,24,27)/t17-/m0/s1
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n/an/an/an/a 1.24E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350621
PNG
(1-(4-bromophenyl)-3-{4-[2-(3- fluorophenyl)ethyl]-...)
Show SMILES CC1(CCc2cccc(F)c2)NC(=O)N(NC(=O)Nc2ccc(Br)cc2)C1=O
Show InChI InChI=1S/C19H18BrFN4O3/c1-19(10-9-12-3-2-4-14(21)11-12)16(26)25(18(28)23-19)24-17(27)22-15-7-5-13(20)6-8-15/h2-8,11H,9-10H2,1H3,(H,23,28)(H2,22,24,27)
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n/an/an/an/a 1.11E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350639
PNG
((2S)-2-{[(2S)-2-{[(4- bromophenyl)carbamoyl]amino}...)
Show SMILES CCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)Nc1ccc(Br)cc1)C(O)=O
Show InChI InChI=1S/C18H26BrN3O4/c1-4-5-14(17(24)25)21-16(23)15(10-11(2)3)22-18(26)20-13-8-6-12(19)7-9-13/h6-9,11,14-15H,4-5,10H2,1-3H3,(H,21,23)(H,24,25)(H2,20,22,26)/t14-,15-/m0/s1
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n/an/an/an/a 1.00E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350659
PNG
((2S)-2-{[(4- iodophenyl)carbamoyl]amino}- 4-methyl...)
Show SMILES CC(C)C[C@H](NC(=O)Nc1ccc(I)cc1)C(O)=O
Show InChI InChI=1S/C13H17IN2O3/c1-8(2)7-11(12(17)18)16-13(19)15-10-5-3-9(14)4-6-10/h3-6,8,11H,7H2,1-2H3,(H,17,18)(H2,15,16,19)/t11-/m0/s1
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n/an/an/an/a 4.00E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350664
PNG
(US10208071, Compound 126 | ethyl hydrogen ({[(2S)-...)
Show SMILES CCOP(O)(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)Nc1ccc(Br)cc1
Show InChI InChI=1S/C19H23BrN3O5P/c1-2-28-29(26,27)13-21-18(24)17(12-14-6-4-3-5-7-14)23-19(25)22-16-10-8-15(20)9-11-16/h3-11,17H,2,12-13H2,1H3,(H,21,24)(H,26,27)(H2,22,23,25)/t17-/m0/s1
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n/an/an/an/a 1.60E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350668
PNG
(US10208071, Compound 130 | {[(2S)-4-methyl-2-({[4-...)
Show SMILES CSc1ccc(NC(=O)N[C@@H](CC(C)C)C(=O)NCC(O)=O)cc1
Show InChI InChI=1S/C16H23N3O4S/c1-10(2)8-13(15(22)17-9-14(20)21)19-16(23)18-11-4-6-12(24-3)7-5-11/h4-7,10,13H,8-9H2,1-3H3,(H,17,22)(H,20,21)(H2,18,19,23)/t13-/m0/s1
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n/an/an/an/a 3.00E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350671
PNG
(2-[1-{[(4- bromophenyl)carbamoyl]amino}- 2,5-dioxo...)
Show SMILES CC(C)C1(CC(=O)NCCO)NC(=O)N(NC(=O)Nc2ccc(Br)cc2)C1=O
Show InChI InChI=1S/C17H22BrN5O5/c1-10(2)17(9-13(25)19-7-8-24)14(26)23(16(28)21-17)22-15(27)20-12-5-3-11(18)4-6-12/h3-6,10,24H,7-9H2,1-2H3,(H,19,25)(H,21,28)(H2,20,22,27)
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n/an/an/an/a 2.70E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350674
PNG
((2S)-4-methyl-N-(1H-tetrazol- 5-ylmethyl)-2-({[4- ...)
Show SMILES CC(C)C[C@H](NC(=O)Nc1ccc(cc1)C(F)(F)F)C(=O)NCc1nnn[nH]1
Show InChI InChI=1S/C16H20F3N7O2/c1-9(2)7-12(14(27)20-8-13-23-25-26-24-13)22-15(28)21-11-5-3-10(4-6-11)16(17,18)19/h3-6,9,12H,7-8H2,1-2H3,(H,20,27)(H2,21,22,28)(H,23,24,25,26)/t12-/m0/s1
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n/an/an/an/a 3.70E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350688
PNG
(2-{2-[1-{[(4- bromophenyl)carbamoyl]amino}- 2,5-di...)
Show SMILES CC(C)C1(CCc2ccccc2C(O)=O)NC(=O)N(NC(=O)Nc2ccc(Br)cc2)C1=O
Show InChI InChI=1S/C22H23BrN4O5/c1-13(2)22(12-11-14-5-3-4-6-17(14)18(28)29)19(30)27(21(32)25-22)26-20(31)24-16-9-7-15(23)8-10-16/h3-10,13H,11-12H2,1-2H3,(H,25,32)(H,28,29)(H2,24,26,31)
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n/an/an/an/a 5.80E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350507
PNG
((2S)-2-({[(3,4- dichlorophenyl)amino]carbonyl}amin...)
Show SMILES OC(=O)C(Cc1ccccc1)NC(=O)Nc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C16H14Cl2N2O3/c17-12-7-6-11(9-13(12)18)19-16(23)20-14(15(21)22)8-10-4-2-1-3-5-10/h1-7,9,14H,8H2,(H,21,22)(H2,19,20,23)
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n/an/an/an/a 1.00E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350527
PNG
(N-(4-bromophenyl)-2-(2,4-dioxo-1,3- diazaspiro[4.5...)
Show SMILES Brc1ccc(NC(=O)CN2C(=O)NC3(CCCCC3)C2=O)cc1
Show InChI InChI=1S/C16H18BrN3O3/c17-11-4-6-12(7-5-11)18-13(21)10-20-14(22)16(19-15(20)23)8-2-1-3-9-16/h4-7H,1-3,8-10H2,(H,18,21)(H,19,23)
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n/an/an/an/a 7.38E+5n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350531
PNG
(N-(4-bromophenyl)-2-(4-cyclopropyl- 4-methyl-2,5-d...)
Show SMILES CC1(NC(=O)N(CC(=O)Nc2ccc(Br)cc2)C1=O)C1CC1
Show InChI InChI=1S/C15H16BrN3O3/c1-15(9-2-3-9)13(21)19(14(22)18-15)8-12(20)17-11-6-4-10(16)5-7-11/h4-7,9H,2-3,8H2,1H3,(H,17,20)(H,18,22)
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n/an/an/an/a 1.66E+5n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350546
PNG
(US10208071, Compound 8 | {[(2S)-2-{[(4- bromopheny...)
Show SMILES CC(C)C[C@H](NC(=O)Nc1ccc(Br)cc1)C(=O)NCC(O)=O
Show InChI InChI=1S/C15H20BrN3O4/c1-9(2)7-12(14(22)17-8-13(20)21)19-15(23)18-11-5-3-10(16)4-6-11/h3-6,9,12H,7-8H2,1-2H3,(H,17,22)(H,20,21)(H2,18,19,23)/t12-/m0/s1
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n/an/an/an/a 780n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350554
PNG
(1-[2-(3-aminopropyl)-3-(4- cyanophenyl)-1-oxo-1,2,...)
Show SMILES CSc1ccc(NC(=O)Nc2ccc3CC(N(CCCN)C(=O)c3c2)c2ccc(cc2)C#N)cc1
Show InChI InChI=1S/C27H27N5O2S/c1-35-23-11-9-21(10-12-23)30-27(34)31-22-8-7-20-15-25(19-5-3-18(17-29)4-6-19)32(14-2-13-28)26(33)24(20)16-22/h3-12,16,25H,2,13-15,28H2,1H3,(H2,30,31,34)
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n/an/an/an/a 2.50E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350559
PNG
(3-[(4- bromophenyl)carbamoyl]-7,7- dimethylbicyclo...)
Show SMILES CC1(C)C2CCC1C(C2C(O)=O)C(=O)Nc1ccc(Br)cc1
Show InChI InChI=1S/C17H20BrNO3/c1-17(2)11-7-8-12(17)14(16(21)22)13(11)15(20)19-10-5-3-9(18)4-6-10/h3-6,11-14H,7-8H2,1-2H3,(H,19,20)(H,21,22)
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n/an/an/an/a 1.00E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350563
PNG
(1-{3-(5-fluoropyridin-2-yl)-2- [2-(1H-imidazol-4-y...)
Show SMILES CS(=O)(=O)c1ccc(NC(=O)Nc2ccc3CC(N(CCc4c[nH]cn4)C(=O)c3c2)c2ccc(F)cn2)cc1
Show InChI InChI=1S/C27H25FN6O4S/c1-39(37,38)22-7-5-19(6-8-22)32-27(36)33-20-4-2-17-12-25(24-9-3-18(28)14-30-24)34(26(35)23(17)13-20)11-10-21-15-29-16-31-21/h2-9,13-16,25H,10-12H2,1H3,(H,29,31)(H2,32,33,36)
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n/an/an/an/a 1.05E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350564
PNG
(N-(4-bromophenyl) spiro[bicyclo[2.2.1]heptane- 7,1...)
Show SMILES NC(=O)C1C2C=CC(C1C(=O)Nc1ccc(Br)cc1)C21CC1
Show InChI InChI=1S/C17H17BrN2O2/c18-9-1-3-10(4-2-9)20-16(22)14-12-6-5-11(13(14)15(19)21)17(12)7-8-17/h1-6,11-14H,7-8H2,(H2,19,21)(H,20,22)
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n/an/an/an/a 4.80E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350567
PNG
(3-{[4- (methylsulfanyl)phenyl]carbamoyl} spiro[bic...)
Show SMILES CSc1ccc(NC(=O)C2C3CCC(C2C(N)=O)C32CC2)cc1
Show InChI InChI=1S/C18H22N2O2S/c1-23-11-4-2-10(3-5-11)20-17(22)15-13-7-6-12(14(15)16(19)21)18(13)8-9-18/h2-5,12-15H,6-9H2,1H3,(H2,19,21)(H,20,22)
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n/an/an/an/a 7.00E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350575
PNG
(7,7-dimethyl-N-[4-(methylsulfanyl) phenyl]bicyclo[...)
Show SMILES CSc1ccc(NC(=O)C2C3CCC(C2C(N)=O)C3(C)C)cc1
Show InChI InChI=1S/C18H24N2O2S/c1-18(2)12-8-9-13(18)15(14(12)16(19)21)17(22)20-10-4-6-11(23-3)7-5-10/h4-7,12-15H,8-9H2,1-3H3,(H2,19,21)(H,20,22)
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n/an/an/an/a 1.70E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350583
PNG
((-) N-(4- bromophenyl)spiro[bicyclo[2.2.1] heptane...)
Show SMILES NC(=O)C1C2CCC(C1C(=O)Nc1ccc(Br)cc1)C21CC1
Show InChI InChI=1S/C17H19BrN2O2/c18-9-1-3-10(4-2-9)20-16(22)14-12-6-5-11(13(14)15(19)21)17(12)7-8-17/h1-4,11-14H,5-8H2,(H2,19,21)(H,20,22)
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n/an/an/an/a<1.00E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350600
PNG
((2S,3S)-N-(2-amino-2- oxoethyl)-2-{[(4-bromo-2- fl...)
Show SMILES CC[C@H](C)[C@H](NC(=O)Nc1ccc(Br)cc1F)C(=O)NCC(N)=O
Show InChI InChI=1S/C15H20BrFN4O3/c1-3-8(2)13(14(23)19-7-12(18)22)21-15(24)20-11-5-4-9(16)6-10(11)17/h4-6,8,13H,3,7H2,1-2H3,(H2,18,22)(H,19,23)(H2,20,21,24)/t8-,13-/m0/s1
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n/an/an/an/a 1.03E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350617
PNG
((2S)-N-(2-amino-2-oxoethyl)- 2-{[(4- bromophenyl)c...)
Show SMILES CCC[C@H](NC(=O)Nc1ccc(Br)cc1)C(=O)NCC(N)=O
Show InChI InChI=1S/C14H19BrN4O3/c1-2-3-11(13(21)17-8-12(16)20)19-14(22)18-10-6-4-9(15)5-7-10/h4-7,11H,2-3,8H2,1H3,(H2,16,20)(H,17,21)(H2,18,19,22)/t11-/m0/s1
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n/an/an/an/a 2.50E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350625
PNG
((2S)-2-{[(2S)-2-{[(4-bromo-2- fluorophenyl)carbamo...)
Show SMILES CC(C)C[C@H](NC(=O)Nc1ccc(Br)cc1F)C(=O)N[C@@H](C)C(O)=O
Show InChI InChI=1S/C16H21BrFN3O4/c1-8(2)6-13(14(22)19-9(3)15(23)24)21-16(25)20-12-5-4-10(17)7-11(12)18/h4-5,7-9,13H,6H2,1-3H3,(H,19,22)(H,23,24)(H2,20,21,25)/t9-,13-/m0/s1
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n/an/an/an/a 1.21E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350632
PNG
((2S)-2-{[(4- bromophenyl)carbamoyl]amino}- N-(1,3-...)
Show SMILES CC(C)C[C@H](NC(=O)Nc1ccc(Br)cc1)C(=O)NC(CO)CO
Show InChI InChI=1S/C16H24BrN3O4/c1-10(2)7-14(15(23)18-13(8-21)9-22)20-16(24)19-12-5-3-11(17)4-6-12/h3-6,10,13-14,21-22H,7-9H2,1-2H3,(H,18,23)(H2,19,20,24)/t14-/m0/s1
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n/an/an/an/a 7.40E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350638
PNG
(US10208071, Compound 100 | tert-butyl (2S)-2-{[(2S...)
Show SMILES CCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)Nc1ccc(Br)cc1)C(=O)OC(C)(C)C
Show InChI InChI=1S/C22H34BrN3O4/c1-7-8-17(20(28)30-22(4,5)6)25-19(27)18(13-14(2)3)26-21(29)24-16-11-9-15(23)10-12-16/h9-12,14,17-18H,7-8,13H2,1-6H3,(H,25,27)(H2,24,26,29)/t17-,18-/m0/s1
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n/an/an/an/a 1.30E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350643
PNG
(US10208071, Compound 105 | ethyl hydrogen ({[(2S)-...)
Show SMILES CCOP(O)(=O)CNC(=O)[C@H](CC(C)C)NC(=O)Nc1ccc(Br)cc1
Show InChI InChI=1S/C16H25BrN3O5P/c1-4-25-26(23,24)10-18-15(21)14(9-11(2)3)20-16(22)19-13-7-5-12(17)6-8-13/h5-8,11,14H,4,9-10H2,1-3H3,(H,18,21)(H,23,24)(H2,19,20,22)/t14-/m0/s1
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n/an/an/an/a 950n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350662
PNG
(US10208071, Compound 124 | {[(2S)-4-methyl-2-({[4-...)
Show SMILES CC(C)C[C@H](NC(=O)Nc1ccc(cc1)C(F)(F)F)C(=O)NCC(O)=O
Show InChI InChI=1S/C16H20F3N3O4/c1-9(2)7-12(14(25)20-8-13(23)24)22-15(26)21-11-5-3-10(4-6-11)16(17,18)19/h3-6,9,12H,7-8H2,1-2H3,(H,20,25)(H,23,24)(H2,21,22,26)/t12-/m0/s1
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n/an/an/an/a 1.80E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350676
PNG
(US10208071, Compound 138 | diethyl ({[(2S)-4-methy...)
Show SMILES CCOP(=O)(CNC(=O)[C@H](CC(C)C)NC(=O)Nc1ccc(SC)cc1)OCC
Show InChI InChI=1S/C19H32N3O5PS/c1-6-26-28(25,27-7-2)13-20-18(23)17(12-14(3)4)22-19(24)21-15-8-10-16(29-5)11-9-15/h8-11,14,17H,6-7,12-13H2,1-5H3,(H,20,23)(H2,21,22,24)/t17-/m0/s1
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n/an/an/an/a 3.50E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350506
PNG
((2S)-3-phenyl-2-[({[4- (trifluoromethyl)phenyl]ami...)
Show SMILES OC(=O)C(Cc1ccccc1)NC(=O)Nc1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C17H15F3N2O3/c18-17(19,20)12-6-8-13(9-7-12)21-16(25)22-14(15(23)24)10-11-4-2-1-3-5-11/h1-9,14H,10H2,(H,23,24)(H2,21,22,25)
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n/an/an/an/a 1.20E+5n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350515
PNG
((2S,3S)-2-({[(4- bromophenyl)amino]carbonyl}amino)...)
Show SMILES CC[C@H](C)[C@H](NC(=O)Nc1ccc(Br)cc1)C(O)=O
Show InChI InChI=1S/C13H17BrN2O3/c1-3-8(2)11(12(17)18)16-13(19)15-10-6-4-9(14)5-7-10/h4-8,11H,3H2,1-2H3,(H,17,18)(H2,15,16,19)/t8-,11-/m0/s1
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n/an/an/an/a 4.10E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350521
PNG
(1-(4-chlorophenyl)-3-(4-ethyl-4- methyl-2,5-dioxoi...)
Show SMILES CCC1(C)NC(=O)N(NC(=O)Nc2ccc(Cl)cc2)C1=O
Show InChI InChI=1S/C13H15ClN4O3/c1-3-13(2)10(19)18(12(21)16-13)17-11(20)15-9-6-4-8(14)5-7-9/h4-7H,3H2,1-2H3,(H,16,21)(H2,15,17,20)
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n/an/an/an/a 1.57E+5n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350526
PNG
(N-(4-bromophenyl)-2-(4,4-diethyl- 2,5-dioxoimidazo...)
Show SMILES CCC1(CC)NC(=O)N(CC(=O)Nc2ccc(Br)cc2)C1=O
Show InChI InChI=1S/C15H18BrN3O3/c1-3-15(4-2)13(21)19(14(22)18-15)9-12(20)17-11-7-5-10(16)6-8-11/h5-8H,3-4,9H2,1-2H3,(H,17,20)(H,18,22)
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n/an/an/an/a 9.60E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350528
PNG
(N-(4-bromophenyl)-2-(2,4-dioxo-1,3- diazaspiro[4.4...)
Show SMILES Brc1ccc(NC(=O)CN2C(=O)NC3(CCCC3)C2=O)cc1
Show InChI InChI=1S/C15H16BrN3O3/c16-10-3-5-11(6-4-10)17-12(20)9-19-13(21)15(18-14(19)22)7-1-2-8-15/h3-6H,1-2,7-9H2,(H,17,20)(H,18,22)
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n/an/an/an/a 3.22E+5n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350533
PNG
(N-(4-bromophenyl)-2-(4-ethyl-4- methyl-2,5-dioxoim...)
Show SMILES CCC1(C)NC(=O)N(CC(=O)Nc2ccc(Br)cc2)C1=O
Show InChI InChI=1S/C14H16BrN3O3/c1-3-14(2)12(20)18(13(21)17-14)8-11(19)16-10-6-4-9(15)5-7-10/h4-7H,3,8H2,1-2H3,(H,16,19)(H,17,21)
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n/an/an/an/a 4.85E+5n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350534
PNG
(N-(4-chlorophenyl)-2-(4,4-diethyl- 2,5-dioxoimidaz...)
Show SMILES CCC1(CC)NC(=O)N(CC(=O)Nc2ccc(Cl)cc2)C1=O
Show InChI InChI=1S/C15H18ClN3O3/c1-3-15(4-2)13(21)19(14(22)18-15)9-12(20)17-11-7-5-10(16)6-8-11/h5-8H,3-4,9H2,1-2H3,(H,17,20)(H,18,22)
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n/an/an/an/a 3.14E+5n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350535
PNG
(2-(4,4-diethyl-2,5-dioxoimidazolidin- 1-yl)-N-(4-f...)
Show SMILES CCC1(CC)NC(=O)N(CC(=O)Nc2ccc(F)cc2)C1=O
Show InChI InChI=1S/C15H18FN3O3/c1-3-15(4-2)13(21)19(14(22)18-15)9-12(20)17-11-7-5-10(16)6-8-11/h5-8H,3-4,9H2,1-2H3,(H,17,20)(H,18,22)
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n/an/an/an/a 2.77E+6n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350536
PNG
(N-(4-bromophenyl)-2-[4-methyl-2,5- dioxo-4-(2-phen...)
Show SMILES CC1(CCc2ccccc2)NC(=O)N(CC(=O)Nc2ccc(Br)cc2)C1=O
Show InChI InChI=1S/C20H20BrN3O3/c1-20(12-11-14-5-3-2-4-6-14)18(26)24(19(27)23-20)13-17(25)22-16-9-7-15(21)8-10-16/h2-10H,11-13H2,1H3,(H,22,25)(H,23,27)
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n/an/an/an/a 8.60E+5n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350560
PNG
(3-[(4- iodophenyl)carbamoyl]-7,7- dimethylbicyclo[...)
Show SMILES CC1(C)C2CCC1C(C2C(O)=O)C(=O)Nc1ccc(I)cc1
Show InChI InChI=1S/C17H20INO3/c1-17(2)11-7-8-12(17)14(16(21)22)13(11)15(20)19-10-5-3-9(18)4-6-10/h3-6,11-14H,7-8H2,1-2H3,(H,19,20)(H,21,22)
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n/an/an/an/a 1.70E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350599
PNG
(1-(4-bromo-2-fluorophenyl)- 3-[4-2,5-dioxo-4- (pro...)
Show SMILES CCC1(NC(=O)N(NC(=O)Nc2ccc(Br)cc2F)C1=O)C(C)C
Show InChI InChI=1S/C15H18BrFN4O3/c1-4-15(8(2)3)12(22)21(14(24)19-15)20-13(23)18-11-6-5-9(16)7-10(11)17/h5-8H,4H2,1-3H3,(H,19,24)(H2,18,20,23)
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n/an/an/an/a 9.20E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350607
PNG
(1-(4-bromo-2-fluorophenyl)- 3-[4-ethyl-2,5-dioxo-4...)
Show SMILES CCC1(CCc2ccccc2)NC(=O)N(NC(=O)Nc2ccc(Br)cc2F)C1=O
Show InChI InChI=1S/C20H20BrFN4O3/c1-2-20(11-10-13-6-4-3-5-7-13)17(27)26(19(29)24-20)25-18(28)23-16-9-8-14(21)12-15(16)22/h3-9,12H,2,10-11H2,1H3,(H,24,29)(H2,23,25,28)
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n/an/an/an/a 1.34E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350629
PNG
((2S)-2-{[(2S)-2-{[(4- bromophenyl)carbamoyl]amino}...)
Show SMILES CC(C)C[C@H](NC(=O)Nc1ccc(Br)cc1)C(=O)N[C@@H](C(C)C)C(O)=O
Show InChI InChI=1S/C18H26BrN3O4/c1-10(2)9-14(16(23)22-15(11(3)4)17(24)25)21-18(26)20-13-7-5-12(19)6-8-13/h5-8,10-11,14-15H,9H2,1-4H3,(H,22,23)(H,24,25)(H2,20,21,26)/t14-,15-/m0/s1
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n/an/an/an/a 1.70E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350630
PNG
((2S)-N-[(2S)-1-amino-3- methyl-1-oxobutan-2-yl]-2-...)
Show SMILES CC(C)C[C@H](NC(=O)Nc1ccc(Br)cc1)C(=O)N[C@@H](C(C)C)C(N)=O
Show InChI InChI=1S/C18H27BrN4O3/c1-10(2)9-14(17(25)23-15(11(3)4)16(20)24)22-18(26)21-13-7-5-12(19)6-8-13/h5-8,10-11,14-15H,9H2,1-4H3,(H2,20,24)(H,23,25)(H2,21,22,26)/t14-,15-/m0/s1
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n/an/an/an/a 5.80E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350631
PNG
((2S)-2-{[(4- bromophenyl)carbamoyl]amino}- N-(2-hy...)
Show SMILES CC(C)C[C@H](NC(=O)Nc1ccc(Br)cc1)C(=O)NCC(C)(C)O
Show InChI InChI=1S/C17H26BrN3O3/c1-11(2)9-14(15(22)19-10-17(3,4)24)21-16(23)20-13-7-5-12(18)6-8-13/h5-8,11,14,24H,9-10H2,1-4H3,(H,19,22)(H2,20,21,23)/t14-/m0/s1
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n/an/an/an/a 2.50E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350633
PNG
((2S)-2-{[(4- bromophenyl)carbamoyl]amino}- N-(2,3-...)
Show SMILES CC(C)C[C@H](NC(=O)Nc1ccc(Br)cc1)C(=O)NCC(O)CO
Show InChI InChI=1S/C16H24BrN3O4/c1-10(2)7-14(15(23)18-8-13(22)9-21)20-16(24)19-12-5-3-11(17)4-6-12/h3-6,10,13-14,21-22H,7-9H2,1-2H3,(H,18,23)(H2,19,20,24)/t13?,14-/m0/s1
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n/an/an/an/a 5.10E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350640
PNG
((2S)-N-[(2S)-1-amino-1- oxopentan-2-yl]-2-{[(4- br...)
Show SMILES CCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)Nc1ccc(Br)cc1)C(N)=O
Show InChI InChI=1S/C18H27BrN4O3/c1-4-5-14(16(20)24)22-17(25)15(10-11(2)3)23-18(26)21-13-8-6-12(19)7-9-13/h6-9,11,14-15H,4-5,10H2,1-3H3,(H2,20,24)(H,22,25)(H2,21,23,26)/t14-,15-/m0/s1
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n/an/an/an/a 7.30E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350655
PNG
(US10208071, Compound 117 | diethyl ({[(2S)-2-{[(4-...)
Show SMILES CCC[C@H](NC(=O)Nc1ccc(Br)cc1)C(=O)NCP(=O)(OCC)OCC
Show InChI InChI=1S/C17H27BrN3O5P/c1-4-7-15(16(22)19-12-27(24,25-5-2)26-6-3)21-17(23)20-14-10-8-13(18)9-11-14/h8-11,15H,4-7,12H2,1-3H3,(H,19,22)(H2,20,21,23)/t15-/m0/s1
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n/an/an/an/a 270n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350656
PNG
(US10208071, Compound 118 | diethyl ({[(2S)-2-{[(4-...)
Show SMILES CCOP(=O)(CNC(=O)[C@H](Cc1ccccc1)NC(=O)Nc1ccc(Br)cc1)OCC
Show InChI InChI=1S/C21H27BrN3O5P/c1-3-29-31(28,30-4-2)15-23-20(26)19(14-16-8-6-5-7-9-16)25-21(27)24-18-12-10-17(22)11-13-18/h5-13,19H,3-4,14-15H2,1-2H3,(H,23,26)(H2,24,25,27)/t19-/m0/s1
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n/an/an/an/a 1.61E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350660
PNG
((2R,3R)-2-{[(4- bromophenyl)carbamoyl]amino}- 3-me...)
Show SMILES CC[C@H](C)[C@@H](NC(=O)Nc1ccc(Br)cc1)C(O)=O
Show InChI InChI=1S/C13H17BrN2O3/c1-3-8(2)11(12(17)18)16-13(19)15-10-6-4-9(14)5-7-10/h4-8,11H,3H2,1-2H3,(H,17,18)(H2,15,16,19)/t8-,11+/m0/s1
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n/an/an/an/a 1.00E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350663
PNG
(US10208071, Compound 125 | dipropan-2-yl ({[(2S)-2...)
Show SMILES CCC[C@H](NC(=O)Nc1ccc(Br)cc1)C(=O)NCP(=O)(OC(C)C)OC(C)C
Show InChI InChI=1S/C19H31BrN3O5P/c1-6-7-17(23-19(25)22-16-10-8-15(20)9-11-16)18(24)21-12-29(26,27-13(2)3)28-14(4)5/h8-11,13-14,17H,6-7,12H2,1-5H3,(H,21,24)(H2,22,23,25)/t17-/m0/s1
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n/an/an/an/a 1.20E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350673
PNG
(US10208071, Compound 135 | ethyl hydrogen ({[(2S)-...)
Show SMILES CCOP(O)(=O)CNC(=O)[C@H](CC(C)C)NC(=O)Nc1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C17H25F3N3O5P/c1-4-28-29(26,27)10-21-15(24)14(9-11(2)3)23-16(25)22-13-7-5-12(6-8-13)17(18,19)20/h5-8,11,14H,4,9-10H2,1-3H3,(H,21,24)(H,26,27)(H2,22,23,25)/t14-/m0/s1
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n/an/an/an/a 1.90E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350678
PNG
(US10208071, Compound 141 | methyl 2-[2-(1-{[(4- br...)
Show SMILES CCC1(CCc2ccccc2C(=O)OC)NC(=O)N(NC(=O)Nc2ccc(Br)cc2)C1=O
Show InChI InChI=1S/C22H23BrN4O5/c1-3-22(13-12-14-6-4-5-7-17(14)18(28)32-2)19(29)27(21(31)25-22)26-20(30)24-16-10-8-15(23)9-11-16/h4-11H,3,12-13H2,1-2H3,(H,25,31)(H2,24,26,30)
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n/an/an/an/a 1.03E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350679
PNG
(2-[1-{[(4- bromophenyl)carbamoyl]amino}- 2,5-dioxo...)
Show SMILES CC(C)C1(CC(=O)NC(CO)CO)NC(=O)N(NC(=O)Nc2ccc(Br)cc2)C1=O
Show InChI InChI=1S/C18H24BrN5O6/c1-10(2)18(7-14(27)20-13(8-25)9-26)15(28)24(17(30)22-18)23-16(29)21-12-5-3-11(19)4-6-12/h3-6,10,13,25-26H,7-9H2,1-2H3,(H,20,27)(H,22,30)(H2,21,23,29)
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n/an/an/an/a 1.38E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350685
PNG
(2-[1-{[(4-bromo-2- fluorophenyl)carbamoyl]amino}- ...)
Show SMILES CC(C)C1(CC(=O)NCCO)NC(=O)N(NC(=O)Nc2ccc(Br)cc2F)C1=O
Show InChI InChI=1S/C17H21BrFN5O5/c1-9(2)17(8-13(26)20-5-6-25)14(27)24(16(29)22-17)23-15(28)21-12-4-3-10(18)7-11(12)19/h3-4,7,9,25H,5-6,8H2,1-2H3,(H,20,26)(H,22,29)(H2,21,23,28)
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n/an/an/an/a 6.90E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350687
PNG
(US10208071, Compound 150 | {[2-{[(4- bromophenyl)c...)
Show SMILES OC(=O)CNC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)Nc1ccc(Br)cc1
Show InChI InChI=1S/C20H19BrN4O4/c21-13-5-7-14(8-6-13)24-20(29)25-17(19(28)23-11-18(26)27)9-12-10-22-16-4-2-1-3-15(12)16/h1-8,10,17,22H,9,11H2,(H,23,28)(H,26,27)(H2,24,25,29)
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n/an/an/an/a 1.40E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350692
PNG
(US10208071, Compound 155 | {[(2S)-2-{[(4- bromophe...)
Show SMILES CC(C)C[C@H](NC(=O)Nc1ccc(Br)cc1)C(=O)N(C)CC(O)=O
Show InChI InChI=1S/C16H22BrN3O4/c1-10(2)8-13(15(23)20(3)9-14(21)22)19-16(24)18-12-6-4-11(17)5-7-12/h4-7,10,13H,8-9H2,1-3H3,(H,21,22)(H2,18,19,24)/t13-/m0/s1
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n/an/an/an/a 1.00E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350505
PNG
((2S)-2-({[(4- methoxyphenyl)amino]carbonyl}amino)-...)
Show SMILES COc1ccc(NC(=O)NC(Cc2ccccc2)C(O)=O)cc1
Show InChI InChI=1S/C17H18N2O4/c1-23-14-9-7-13(8-10-14)18-17(22)19-15(16(20)21)11-12-5-3-2-4-6-12/h2-10,15H,11H2,1H3,(H,20,21)(H2,18,19,22)
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n/an/an/an/a 1.75E+6n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350522
PNG
(1-[4-methyl-2,5-dioxo-4-(2- phenylethyl)imidazolid...)
Show SMILES CC1(CCc2ccccc2)NC(=O)N(NC(=O)Nc2ccccc2)C1=O
Show InChI InChI=1S/C19H20N4O3/c1-19(13-12-14-8-4-2-5-9-14)16(24)23(18(26)21-19)22-17(25)20-15-10-6-3-7-11-15/h2-11H,12-13H2,1H3,(H,21,26)(H2,20,22,25)
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n/an/an/an/a 2.23E+5n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350523
PNG
(1-(8-methyl-2,4-dioxo-1,3- diazaspiro[4,5]decan-3-...)
Show SMILES CC1CCC2(CC1)NC(=O)N(NC(=O)Nc1ccc(C)cc1)C2=O
Show InChI InChI=1S/C17H22N4O3/c1-11-3-5-13(6-4-11)18-15(23)20-21-14(22)17(19-16(21)24)9-7-12(2)8-10-17/h3-6,12H,7-10H2,1-2H3,(H,19,24)(H2,18,20,23)
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n/an/an/an/a 3.63E+5n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350530
PNG
(N-(4-bromophenyl)-2-(4-ethyl-2,5- dioxo-4-phenylim...)
Show SMILES CCC1(NC(=O)N(CC(=O)Nc2ccc(Br)cc2)C1=O)c1ccccc1
Show InChI InChI=1S/C19H18BrN3O3/c1-2-19(13-6-4-3-5-7-13)17(25)23(18(26)22-19)12-16(24)21-15-10-8-14(20)9-11-15/h3-11H,2,12H2,1H3,(H,21,24)(H,22,26)
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n/an/an/an/a 5.23E+5n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350543
PNG
((2S,3S)-2-{[(4-bromo-2- fluorophenyl)carbamoyl]ami...)
Show SMILES CC[C@H](C)[C@H](NC(=O)Nc1ccc(Br)cc1F)C(O)=O
Show InChI InChI=1S/C13H16BrFN2O3/c1-3-7(2)11(12(18)19)17-13(20)16-10-5-4-8(14)6-9(10)15/h4-7,11H,3H2,1-2H3,(H,18,19)(H2,16,17,20)/t7-,11-/m0/s1
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n/an/an/an/a 3.10E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350548
PNG
(2-{[(4- bromophenyl)carbamoyl]amino}-N- (2-oxoazep...)
Show SMILES Brc1ccc(NC(=O)NC(Cc2ccccc2)C(=O)NC2CCCCNC2=O)cc1
Show InChI InChI=1S/C22H25BrN4O3/c23-16-9-11-17(12-10-16)25-22(30)27-19(14-15-6-2-1-3-7-15)21(29)26-18-8-4-5-13-24-20(18)28/h1-3,6-7,9-12,18-19H,4-5,8,13-14H2,(H,24,28)(H,26,29)(H2,25,27,30)
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n/an/an/an/a 1.10E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350552
PNG
(US10208071, Compound 14 | rel-(2R,3S)-3-[(4- bromo...)
Show SMILES OC(=O)C1C2CCC(C1C(=O)Nc1ccc(Br)cc1)C21CC1
Show InChI InChI=1S/C17H17BrNO3/c18-9-1-3-10(4-2-9)19-15(20)13-11-5-6-12(14(13)16(21)22)17(11)7-8-17/h1-3,11-14H,5-8H2,(H,19,20)(H,21,22)
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n/an/an/an/a 4.00E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350561
PNG
(1-{3-(furan-2-yl)-2-[2-(1H- imidazol-4-yl)ethyl]-1...)
Show SMILES CSc1ccc(NC(=O)Nc2ccc3CC(N(CCc4c[nH]cn4)C(=O)c3c2)c2ccco2)cc1
Show InChI InChI=1S/C26H25N5O3S/c1-35-21-8-6-18(7-9-21)29-26(33)30-19-5-4-17-13-23(24-3-2-12-34-24)31(25(32)22(17)14-19)11-10-20-15-27-16-28-20/h2-9,12,14-16,23H,10-11,13H2,1H3,(H,27,28)(H2,29,30,33)
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n/an/an/an/a 1.90E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350569
PNG
(3-{[4- (methylsulfanyl)phenyl]carbamoyl} spiro[bic...)
Show SMILES CSc1ccc(NC(=O)C2C3C=CC(C2C(N)=O)C32CC2)cc1
Show InChI InChI=1S/C18H20N2O2S/c1-23-11-4-2-10(3-5-11)20-17(22)15-13-7-6-12(14(15)16(19)21)18(13)8-9-18/h2-7,12-15H,8-9H2,1H3,(H2,19,21)(H,20,22)
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n/an/an/an/a 1.40E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350570
PNG
(1-{3-(5-chloropyridin-2-yl)-2- [2-(1H-imidazol-4-y...)
Show SMILES CSc1ccc(NC(=O)Nc2ccc3CC(N(CCc4c[nH]cn4)C(=O)c3c2)c2ccc(Cl)cn2)cc1
Show InChI InChI=1S/C27H25ClN6O2S/c1-37-22-7-5-19(6-8-22)32-27(36)33-20-4-2-17-12-25(24-9-3-18(28)14-30-24)34(26(35)23(17)13-20)11-10-21-15-29-16-31-21/h2-9,13-16,25H,10-12H2,1H3,(H,29,31)(H2,32,33,36)
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n/an/an/an/a 1.35E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350574
PNG
((+)1-[(3R)-2-(3-aminopropyl)- 3-(4-cyanophenyl)-1-...)
Show SMILES CSc1ccc(NC(=O)Nc2ccc3CC(N(CCCN)C(=O)c3c2)c2ccc(cc2)C#N)cc1
Show InChI InChI=1S/C27H27N5O2S/c1-35-23-11-9-21(10-12-23)30-27(34)31-22-8-7-20-15-25(19-5-3-18(17-29)4-6-19)32(14-2-13-28)26(33)24(20)16-22/h3-12,16,25H,2,13-15,28H2,1H3,(H2,30,31,34)
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n/an/an/an/a 3.30E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350584
PNG
(N-(4-bromophenyl)-N'- methylspiro[bicyclo[2.2.1]he...)
Show SMILES CNC(=O)C1C2CCC(C1C(=O)Nc1ccc(Br)cc1)C21CC1
Show InChI InChI=1S/C18H21BrN2O2/c1-20-16(22)14-12-6-7-13(18(12)8-9-18)15(14)17(23)21-11-4-2-10(19)3-5-11/h2-5,12-15H,6-9H2,1H3,(H,20,22)(H,21,23)
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n/an/an/an/a 8.50E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350587
PNG
(1-(4-bromophenyl)-3-(4,4- diethyl-2,5-dioxoimidazo...)
Show SMILES CCC1(CC)NC(=O)N(NC(=O)Nc2ccc(Br)cc2)C1=O
Show InChI InChI=1S/C14H17BrN4O3/c1-3-14(4-2)11(20)19(13(22)17-14)18-12(21)16-10-7-5-9(15)6-8-10/h5-8H,3-4H2,1-2H3,(H,17,22)(H2,16,18,21)
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n/an/an/an/a 1.15E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350594
PNG
(3-{[(2S)-2-{[(4- bromophenyl)carbamoyl]amino}-3- p...)
Show SMILES OC(=O)CCNC(=O)[C@H](Cc1ccccc1)NC(=O)Nc1ccc(Br)cc1
Show InChI InChI=1S/C19H20BrN3O4/c20-14-6-8-15(9-7-14)22-19(27)23-16(12-13-4-2-1-3-5-13)18(26)21-11-10-17(24)25/h1-9,16H,10-12H2,(H,21,26)(H,24,25)(H2,22,23,27)/t16-/m0/s1
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n/an/an/an/a 1.80E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350595
PNG
((+) 1-(4-bromophenyl)-3-[4- methyl-2,5-dioxo-4-(2-...)
Show SMILES CC1(CCc2ccccc2)NC(=O)N(NC(=O)Nc2ccc(Br)cc2)C1=O
Show InChI InChI=1S/C19H19BrN4O3/c1-19(12-11-13-5-3-2-4-6-13)16(25)24(18(27)22-19)23-17(26)21-15-9-7-14(20)8-10-15/h2-10H,11-12H2,1H3,(H,22,27)(H2,21,23,26)
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n/an/an/an/a 3.20E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350610
PNG
(US10208071, Compound 72 | methyl{[(2S)-2-{[(4- bro...)
Show SMILES CCC[C@H](NC(=O)Nc1ccc(Br)cc1)C(=O)NCC(=O)OC
Show InChI InChI=1S/C15H20BrN3O4/c1-3-4-12(14(21)17-9-13(20)23-2)19-15(22)18-11-7-5-10(16)6-8-11/h5-8,12H,3-4,9H2,1-2H3,(H,17,21)(H2,18,19,22)/t12-/m0/s1
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n/an/an/an/a 1.64E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350613
PNG
((2S)-2-{[(4- bromophenyl)carbamoyl]amino}- N-(2-hy...)
Show SMILES CC(C)C[C@H](NC(=O)Nc1ccc(Br)cc1)C(=O)NCCO
Show InChI InChI=1S/C15H22BrN3O3/c1-10(2)9-13(14(21)17-7-8-20)19-15(22)18-12-5-3-11(16)4-6-12/h3-6,10,13,20H,7-9H2,1-2H3,(H,17,21)(H2,18,19,22)/t13-/m0/s1
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n/an/an/an/a 1.35E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350618
PNG
(1-(4-bromophenyl)-3-{4-[2-(2- fluorophenyl)ethyl]-...)
Show SMILES CC1(CCc2ccccc2F)NC(=O)N(NC(=O)Nc2ccc(Br)cc2)C1=O
Show InChI InChI=1S/C19H18BrFN4O3/c1-19(11-10-12-4-2-3-5-15(12)21)16(26)25(18(28)23-19)24-17(27)22-14-8-6-13(20)7-9-14/h2-9H,10-11H2,1H3,(H,23,28)(H2,22,24,27)
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n/an/an/an/a 1.43E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350620
PNG
(1-(4-bromophenyl)-3-{4-[2-(4- fluorophenyl)ethyl]-...)
Show SMILES CC1(CCc2ccc(F)cc2)NC(=O)N(NC(=O)Nc2ccc(Br)cc2)C1=O
Show InChI InChI=1S/C19H18BrFN4O3/c1-19(11-10-12-2-6-14(21)7-3-12)16(26)25(18(28)23-19)24-17(27)22-15-8-4-13(20)5-9-15/h2-9H,10-11H2,1H3,(H,23,28)(H2,22,24,27)
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n/an/an/an/a 1.63E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350641
PNG
((2S)-{[(2S)-2-{[(4- bromophenyl)carbamoyl]amino}- ...)
Show SMILES CC(C)C[C@H](NC(=O)Nc1ccc(Br)cc1)C(=O)N[C@H](C(O)=O)c1ccccc1
Show InChI InChI=1S/C21H24BrN3O4/c1-13(2)12-17(24-21(29)23-16-10-8-15(22)9-11-16)19(26)25-18(20(27)28)14-6-4-3-5-7-14/h3-11,13,17-18H,12H2,1-2H3,(H,25,26)(H,27,28)(H2,23,24,29)/t17-,18-/m0/s1
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n/an/an/an/a 9.10E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350644
PNG
(1-(4-bromo-2-fluorophenyl)- 3-{4-[2-(2- hydroxyphe...)
Show SMILES CC1(CCc2ccccc2O)NC(=O)N(NC(=O)Nc2ccc(Br)cc2F)C1=O
Show InChI InChI=1S/C19H18BrFN4O4/c1-19(9-8-11-4-2-3-5-15(11)26)16(27)25(18(29)23-19)24-17(28)22-14-7-6-12(20)10-13(14)21/h2-7,10,26H,8-9H2,1H3,(H,23,29)(H2,22,24,28)
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n/an/an/an/a 4.00E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350654
PNG
((2S)-2-{[(4- bromophenyl)carbamoyl]amino}- N-[(3-h...)
Show SMILES CC(C)C[C@H](NC(=O)Nc1ccc(Br)cc1)C(=O)NCc1cc(O)no1
Show InChI InChI=1S/C17H21BrN4O4/c1-10(2)7-14(16(24)19-9-13-8-15(23)22-26-13)21-17(25)20-12-5-3-11(18)4-6-12/h3-6,8,10,14H,7,9H2,1-2H3,(H,19,24)(H,22,23)(H2,20,21,25)/t14-/m0/s1
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n/an/an/an/a 1.20E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350677
PNG
(2-methyl-2-{[(2S)-4-methyl-2-({[4- (trifluoromethy...)
Show SMILES CC(C)C[C@H](NC(=O)Nc1ccc(cc1)C(F)(F)F)C(=O)NC(C)(C)C(O)=O
Show InChI InChI=1S/C18H24F3N3O4/c1-10(2)9-13(14(25)24-17(3,4)15(26)27)23-16(28)22-12-7-5-11(6-8-12)18(19,20)21/h5-8,10,13H,9H2,1-4H3,(H,24,25)(H,26,27)(H2,22,23,28)/t13-/m0/s1
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n/an/an/an/a 2.50E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350681
PNG
(US10208071, Compound 144 | {[(2S)-2-{[(4- bromophe...)
Show SMILES CSCC[C@H](NC(=O)Nc1ccc(Br)cc1)C(=O)NCC(O)=O
Show InChI InChI=1S/C14H18BrN3O4S/c1-23-7-6-11(13(21)16-8-12(19)20)18-14(22)17-10-4-2-9(15)3-5-10/h2-5,11H,6-8H2,1H3,(H,16,21)(H,19,20)(H2,17,18,22)/t11-/m0/s1
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n/an/an/an/a 6.30E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%