Compile Data Set for Download or QSAR
maximum 50k data
Found 155 Enz. Inhib. hit(s) with all data for entry = 2232
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358175(US10214544, Example 3 | tert-Butyl (3-(((6-methoxy...)
Affinity DataEC50:  2.60nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358177(3-(((6-Methoxy-2-(2-methoxyimidazo[2,1-b][1,3,4]th...)
Affinity DataEC50:  17nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358183(4-Chloro-N-(3-(((6-methoxy-2-(2-methoxyimidazo[2,1...)
Affinity DataEC50:  1.30nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358187(N-(3-(((6-methoxy-2-(2-methoxyimidazo[2,1-b][1,3,4...)
Affinity DataEC50:  1.40nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358191(N-(3-(((6-methoxy-2-(2-methoxyimidazo[2,1-b][1,3,4...)
Affinity DataEC50:  10nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358193(US10214544, Example 8)
Affinity DataEC50:  1.60nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358194(US10214544, Example 9)
Affinity DataEC50:  2nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358197(US10214544, Example 10)
Affinity DataEC50:  1.90nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358198(US10214544, Example 11)
Affinity DataEC50:  1.70nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358202(US10214544, Example 12)
Affinity DataEC50:  1.5nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358219(US10214544, Example 13)
Affinity DataEC50:  1.90nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358220(US10214544, Example 14)
Affinity DataEC50:  1.40nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358221(US10214544, Example 15)
Affinity DataEC50:  1.70nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358222(US10214544, Example 16)
Affinity DataEC50:  1.40nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358233(US10214544, Example 17)
Affinity DataEC50:  0.550nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358234(US10214544, Example 18)
Affinity DataEC50:  0.910nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358255(US10214544, Example 19)
Affinity DataEC50:  3.30nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358259(US10214544, Example 20)
Affinity DataEC50:  1.40nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358260(US10214544, Example 21)
Affinity DataEC50:  1.5nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358265(US10214544, Example 22)
Affinity DataEC50:  1.10nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358266(US10214544, Example 23)
Affinity DataEC50:  1.80nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358280(US10214544, Example 24)
Affinity DataEC50:  1.40nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358343(US10214544, Example 25)
Affinity DataEC50:  1.70nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358408(US10214544, Example 26)
Affinity DataEC50:  0.75nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358409(US10214544, Example 27)
Affinity DataEC50:  0.870nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358410(US10214544, Example 28)
Affinity DataEC50:  2nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358411(US10214544, Example 29)
Affinity DataEC50:  1.10nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358465(US10214544, Example 30)
Affinity DataEC50:  1.80nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358473(US10214544, Example 31)
Affinity DataEC50:  1.30nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358474(US10214544, Example 32)
Affinity DataEC50:  1.60nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358481(US10214544, Example 33)
Affinity DataEC50:  1.80nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358487(US10214544, Example 34)
Affinity DataEC50:  1.20nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358488(US10214544, Example 35)
Affinity DataEC50:  1nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358491(US10214544, Example 36)
Affinity DataEC50:  2.5nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358496(US10214544, Example 37)
Affinity DataEC50:  2.5nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358497(US10214544, Example 38)
Affinity DataEC50:  4.80nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358503(US10214544, Example 39)
Affinity DataEC50:  2.40nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358504(US10214544, Example 40)
Affinity DataEC50:  1.40nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358508(US10214544, Example 41)
Affinity DataEC50:  1.40nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358510(US10214544, Example 42)
Affinity DataEC50:  2.30nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358517(US10214544, Example 43)
Affinity DataEC50:  1.60nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358521(US10214544, Example 155 | US10214544, Example 44)
Affinity DataEC50:  2.30nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358522(US10214544, Example 45)
Affinity DataEC50:  2.80nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358523(US10214544, Example 46)
Affinity DataEC50:  1.10nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358541(US10214544, Example 47)
Affinity DataEC50:  6.90nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358542(US10214544, Example 48)
Affinity DataEC50:  2.70nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358548(US10214544, Example 49)
Affinity DataEC50:  0.850nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358549(US10214544, Example 50)
Affinity DataEC50:  7.40nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358551(US10214544, Example 51)
Affinity DataEC50:  2.30nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM358552(US10214544, Example 52)
Affinity DataEC50:  0.410nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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