Compile Data Set for Download or QSAR
maximum 50k data
Found 48 Enz. Inhib. hit(s) with all data for entry = 2541
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370580(US10238638, Example 9)
Affinity DataIC50:  330nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370593(US10238638, Example 22)
Affinity DataIC50:  760nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370592(US10238638, Example 21)
Affinity DataIC50:  920nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370620(US10238638, Example 67)
Affinity DataIC50:  930nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370581(US10238638, Example 10)
Affinity DataIC50:  980nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370613(US10238638, Example 42)
Affinity DataIC50:  1.10E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370497(US10238638, Example 5)
Affinity DataIC50:  1.10E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370591(US10238638, Example 20)
Affinity DataIC50:  1.20E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370606(US10238638, Example 35)
Affinity DataIC50:  1.20E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370598(US10238638, Example 27)
Affinity DataIC50:  1.20E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370605(US10238638, Example 34)
Affinity DataIC50:  1.30E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370607(US10238638, Example 36)
Affinity DataIC50:  1.30E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370603(US10238638, Example 32)
Affinity DataIC50:  1.40E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370582(US10238638, Example 11)
Affinity DataIC50:  1.40E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370610(US10238638, Example 40)
Affinity DataIC50:  1.60E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370608((S)-(3-Hydroxypiperidin-1-yl)(4-(4-(((5-methoxy-2-...)
Affinity DataIC50:  1.60E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370612(US10238638, Example 41)
Affinity DataIC50:  1.70E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370616(5-Methoxy-2-(6-methylimidazo[1,2-b]pyridazin-2-yl)...)
Affinity DataIC50:  1.80E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370609(US10238638, Example 39)
Affinity DataIC50:  1.80E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370579(US10238638, Example 8)
Affinity DataIC50:  1.80E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370602(US10238638, Example 31 | tert-Butyl 4-(4-(((2-(2-e...)
Affinity DataIC50:  2.00E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370432(US10238638, Example 1)
Affinity DataIC50:  2.40E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370617(US10238638, Example 46)
Affinity DataIC50:  2.50E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370596((S)-4-(4-(((2-(2-Cyclopropylimidazo[2,1-b][1,3,4]t...)
Affinity DataIC50:  2.60E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370588(US10238638, Example 17)
Affinity DataIC50:  2.60E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370615(4-(4-(((5-Methoxy-2-(6-methylimidazo[1,2-b]pyridaz...)
Affinity DataIC50:  2.60E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370450(US10238638, Example 3)
Affinity DataIC50:  3.60E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370604(US10238638, Example 33)
Affinity DataIC50:  3.60E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370599(US10238638, Example 28)
Affinity DataIC50:  3.70E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370586(US10238638, Example 15)
Affinity DataIC50:  3.70E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370498(US10238638, Example 6)
Affinity DataIC50:  3.80E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370496(US10238638, Example 4)
Affinity DataIC50:  4.20E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370589(US10238638, Example 18)
Affinity DataIC50:  5.10E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370618((S)-4-(4-(((5-Methoxy-2-(6-methylimidazo[1,2-b]pyr...)
Affinity DataIC50:  6.40E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370597(US10238638, Example 26)
Affinity DataIC50:  9.10E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370619(US10238638, Example 48)
Affinity DataIC50:  9.90E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370587(US10238638, Example 16)
Affinity DataIC50:  1.50E+4nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370499(US10238638, Example 7)
Affinity DataIC50:  3.00E+4nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370449(US10238638, Example 2)
Affinity DataIC50:  4.50E+4nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370600(US10238638, Example 29)
Affinity DataIC50:  8.00E+4nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370590(US10238638, Example 19)
Affinity DataIC50:  8.10E+4nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370585(US10238638, Example 14)
Affinity DataIC50:  8.70E+4nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370601(US10238638, Example 30)
Affinity DataIC50:  3.20E+5nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370595(US10238638, Example 24 | tert-Butyl 4-(4-(((2-(2-c...)
Affinity DataIC50:  3.80E+5nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370614(US10238638, Example 43)
Affinity DataIC50:  5.00E+5nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370584(US10238638, Example 13 | tert-Butyl 4-(4-(((2-(2-(...)
Affinity DataIC50:  8.00E+5nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370594(US10238638, Example 23)
Affinity DataIC50:  8.30E+5nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPRKC apoptosis WT1 regulator protein(Homo sapiens (Human))
Universite De Montreal

US Patent
LigandPNGBDBM370583(7-(Benzyloxy)-2-(2-(1,1-difluoroethyl)imidazo[2,1-...)
Affinity DataIC50:  3.20E+6nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent