Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Oxysterols receptor LXR-beta (Homo sapiens (Human)) | BDBM372430![]() (1-(cyclopropylmethyl)- 5-(3'-(methylsulfonyl)- [1,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | <1.00E+3 | n/a | n/a | n/a | n/a |
RALEXAR THERAPEUTICS, INC. US Patent | Assay Description For transient transfection of HEK 293 cells, 6×103 cells are plated into 96-well dishes. Each well is transfected with 25 ng 5×UAS-luciferase reporte... | US Patent US10246419 (2019) BindingDB Entry DOI: 10.7270/Q2GT5QHJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxysterols receptor LXR-beta (Homo sapiens (Human)) | BDBM372424![]() (US10246419, Compound 10 | US10246419, Compound 7) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | <1.00E+3 | n/a | n/a | n/a | n/a |
RALEXAR THERAPEUTICS, INC. US Patent | Assay Description For transient transfection of HEK 293 cells, 6×103 cells are plated into 96-well dishes. Each well is transfected with 25 ng 5×UAS-luciferase reporte... | US Patent US10246419 (2019) BindingDB Entry DOI: 10.7270/Q2GT5QHJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxysterols receptor LXR-beta (Homo sapiens (Human)) | BDBM372428![]() (US10246419, Compound 11) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a |
RALEXAR THERAPEUTICS, INC. US Patent | Assay Description For transient transfection of HEK 293 cells, 6×103 cells are plated into 96-well dishes. Each well is transfected with 25 ng 5×UAS-luciferase reporte... | US Patent US10246419 (2019) BindingDB Entry DOI: 10.7270/Q2GT5QHJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxysterols receptor LXR-beta (Homo sapiens (Human)) | BDBM372429![]() (US10246419, Compound 12) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a |
RALEXAR THERAPEUTICS, INC. US Patent | Assay Description For transient transfection of HEK 293 cells, 6×103 cells are plated into 96-well dishes. Each well is transfected with 25 ng 5×UAS-luciferase reporte... | US Patent US10246419 (2019) BindingDB Entry DOI: 10.7270/Q2GT5QHJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxysterols receptor LXR-beta (Homo sapiens (Human)) | BDBM372421![]() (US10246419, Compound 4) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | <1.00E+3 | n/a | n/a | n/a | n/a |
RALEXAR THERAPEUTICS, INC. US Patent | Assay Description For transient transfection of HEK 293 cells, 6×103 cells are plated into 96-well dishes. Each well is transfected with 25 ng 5×UAS-luciferase reporte... | US Patent US10246419 (2019) BindingDB Entry DOI: 10.7270/Q2GT5QHJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxysterols receptor LXR-beta (Homo sapiens (Human)) | BDBM372423![]() (US10246419, Compound 6) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | <1.00E+3 | n/a | n/a | n/a | n/a |
RALEXAR THERAPEUTICS, INC. US Patent | Assay Description For transient transfection of HEK 293 cells, 6×103 cells are plated into 96-well dishes. Each well is transfected with 25 ng 5×UAS-luciferase reporte... | US Patent US10246419 (2019) BindingDB Entry DOI: 10.7270/Q2GT5QHJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxysterols receptor LXR-beta (Homo sapiens (Human)) | BDBM372424![]() (US10246419, Compound 10 | US10246419, Compound 7) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a |
RALEXAR THERAPEUTICS, INC. US Patent | Assay Description For transient transfection of HEK 293 cells, 6×103 cells are plated into 96-well dishes. Each well is transfected with 25 ng 5×UAS-luciferase reporte... | US Patent US10246419 (2019) BindingDB Entry DOI: 10.7270/Q2GT5QHJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxysterols receptor LXR-beta (Homo sapiens (Human)) | BDBM372433![]() (US10246419, Compound 21) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | <1.00E+3 | n/a | n/a | n/a | n/a |
RALEXAR THERAPEUTICS, INC. US Patent | Assay Description For transient transfection of HEK 293 cells, 6×103 cells are plated into 96-well dishes. Each well is transfected with 25 ng 5×UAS-luciferase reporte... | US Patent US10246419 (2019) BindingDB Entry DOI: 10.7270/Q2GT5QHJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxysterols receptor LXR-beta (Homo sapiens (Human)) | BDBM372425![]() (US10246419, Compound 8) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a |
RALEXAR THERAPEUTICS, INC. US Patent | Assay Description For transient transfection of HEK 293 cells, 6×103 cells are plated into 96-well dishes. Each well is transfected with 25 ng 5×UAS-luciferase reporte... | US Patent US10246419 (2019) BindingDB Entry DOI: 10.7270/Q2GT5QHJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxysterols receptor LXR-beta (Homo sapiens (Human)) | BDBM372426![]() (US10246419, Compound 9) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a |
RALEXAR THERAPEUTICS, INC. US Patent | Assay Description For transient transfection of HEK 293 cells, 6×103 cells are plated into 96-well dishes. Each well is transfected with 25 ng 5×UAS-luciferase reporte... | US Patent US10246419 (2019) BindingDB Entry DOI: 10.7270/Q2GT5QHJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxysterols receptor LXR-beta (Homo sapiens (Human)) | BDBM372432![]() (1-cyclohexyl-5-(3'- (methylsulfonyl)-[1,1'- biphen...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
RALEXAR THERAPEUTICS, INC. US Patent | Assay Description For transient transfection of HEK 293 cells, 6×103 cells are plated into 96-well dishes. Each well is transfected with 25 ng 5×UAS-luciferase reporte... | US Patent US10246419 (2019) BindingDB Entry DOI: 10.7270/Q2GT5QHJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxysterols receptor LXR-beta (Homo sapiens (Human)) | BDBM372422![]() (US10246419, Compound 5) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | <1.00E+3 | n/a | n/a | n/a | n/a |
RALEXAR THERAPEUTICS, INC. US Patent | Assay Description For transient transfection of HEK 293 cells, 6×103 cells are plated into 96-well dishes. Each well is transfected with 25 ng 5×UAS-luciferase reporte... | US Patent US10246419 (2019) BindingDB Entry DOI: 10.7270/Q2GT5QHJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxysterols receptor LXR-beta (Homo sapiens (Human)) | BDBM372431![]() (1-(sec-butyl)-5-(3'- (methylsulfonyl)-[1,1'- biphe...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
RALEXAR THERAPEUTICS, INC. US Patent | Assay Description For transient transfection of HEK 293 cells, 6×103 cells are plated into 96-well dishes. Each well is transfected with 25 ng 5×UAS-luciferase reporte... | US Patent US10246419 (2019) BindingDB Entry DOI: 10.7270/Q2GT5QHJ | |||||||||||
More data for this Ligand-Target Pair |