Compile Data Set for Download or QSAR
maximum 50k data
Found 16 Enz. Inhib. hit(s) with all data for entry = 2587
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Parion Sciences

US Patent
LigandPNGBDBM372436(3,5-diamino-N-(N-(4-(4-((S)-4-amino-3-(3-(hexyl((2...)
Affinity DataIC50:  2.60nMAssay Description:One assay used to assess mechanism of action and/or potency of the compounds of the present invention involves the determination of lumenal drug inhi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Parion Sciences

US Patent
LigandPNGBDBM372443(US10246425, Compound XVII-d)
Affinity DataIC50:  2.90nMAssay Description:One assay used to assess mechanism of action and/or potency of the compounds of the present invention involves the determination of lumenal drug inhi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Parion Sciences

US Patent
LigandPNGBDBM372448(3,5-diamino-N-(N-(4-(4-((S)-3-amino-2-(3-(bis((2S,...)
Affinity DataIC50:  5.5nMAssay Description:One assay used to assess mechanism of action and/or potency of the compounds of the present invention involves the determination of lumenal drug inhi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Parion Sciences

US Patent
LigandPNGBDBM372440(3,5-diamino-N-(N-(4-(6-((S)-4-amino-3-(3-(hexyl((2...)
Affinity DataIC50:  6nMAssay Description:One assay used to assess mechanism of action and/or potency of the compounds of the present invention involves the determination of lumenal drug inhi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Parion Sciences

US Patent
LigandPNGBDBM372441(3,5-diamino-N-(N-(4-(4-((S)-4-amino-3-(3-(bis((2S,...)
Affinity DataIC50:  7.30nMAssay Description:One assay used to assess mechanism of action and/or potency of the compounds of the present invention involves the determination of lumenal drug inhi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Parion Sciences

US Patent
LigandPNGBDBM372449(3,5-diamino-N-(N-(4-(4-((S)-3-amino-2-(3-(hexyl((2...)
Affinity DataIC50:  8.40nMAssay Description:One assay used to assess mechanism of action and/or potency of the compounds of the present invention involves the determination of lumenal drug inhi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Parion Sciences

US Patent
LigandPNGBDBM372445(3,5-diamino-N-(N-(4-(4-((S)-3-amino-2-(3-(hexyl((2...)
Affinity DataIC50:  8.80nMAssay Description:One assay used to assess mechanism of action and/or potency of the compounds of the present invention involves the determination of lumenal drug inhi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Parion Sciences

US Patent
LigandPNGBDBM372435(3,5-diamino-N-(N-(4-(4-((S)-4-amino-3-(3-(bis((2S,...)
Affinity DataIC50:  10.6nMAssay Description:One assay used to assess mechanism of action and/or potency of the compounds of the present invention involves the determination of lumenal drug inhi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Parion Sciences

US Patent
LigandPNGBDBM372447(3,5-diamino-N-(N-(4-(6-((S)-3-amino-2-(3-(hexyl((2...)
Affinity DataIC50:  11.3nMAssay Description:One assay used to assess mechanism of action and/or potency of the compounds of the present invention involves the determination of lumenal drug inhi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Parion Sciences

US Patent
LigandPNGBDBM372439(3,5-diamino-N-(N-(4-(6-((S)-4-amino-3-(3-(bis((2S,...)
Affinity DataIC50:  12.5nMAssay Description:One assay used to assess mechanism of action and/or potency of the compounds of the present invention involves the determination of lumenal drug inhi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Parion Sciences

US Patent
LigandPNGBDBM372438(3,5-diamino-N-(N-(4-(4-((S)-4-amino-3-(3-(hexyl((2...)
Affinity DataIC50:  14.3nMAssay Description:One assay used to assess mechanism of action and/or potency of the compounds of the present invention involves the determination of lumenal drug inhi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Parion Sciences

US Patent
LigandPNGBDBM372437(3,5-diamino-N-(N-(4-(4-((S)-4-amino-3-(3-(bis((2S,...)
Affinity DataIC50:  24nMAssay Description:One assay used to assess mechanism of action and/or potency of the compounds of the present invention involves the determination of lumenal drug inhi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Parion Sciences

US Patent
LigandPNGBDBM372446(3,5-diamino-N-(N-(4-(6-((S)-3-amino-2-(3-(bis((2S,...)
Affinity DataIC50:  27.4nMAssay Description:One assay used to assess mechanism of action and/or potency of the compounds of the present invention involves the determination of lumenal drug inhi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Parion Sciences

US Patent
LigandPNGBDBM372442(US10246425, Compound XVI-ee)
Affinity DataIC50:  35.6nMAssay Description:One assay used to assess mechanism of action and/or potency of the compounds of the present invention involves the determination of lumenal drug inhi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Parion Sciences

US Patent
LigandPNGBDBM372444(3,5-diamino-N-(N-(4-(4-((S)-3-amino-2-(3-(bis((2S,...)
Affinity DataIC50:  40.8nMAssay Description:One assay used to assess mechanism of action and/or potency of the compounds of the present invention involves the determination of lumenal drug inhi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Parion Sciences

US Patent
LigandPNGBDBM16173(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)
Affinity DataIC50:  781nMAssay Description:One assay used to assess mechanism of action and/or potency of the compounds of the present invention involves the determination of lumenal drug inhi...More data for this Ligand-Target Pair
In DepthDetails US Patent