Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM81790![]() (Amisulpride | CAS_71675-85-9 | NSC_2159 | US101672...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | Purchase CHEBI DrugBank PC cid PC sid UniChem Patents Similars | DrugBank US Patent | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
LB PHARMACEUTICALS INC. US Patent | Assay Description The ability of Compound 102 to bind dopamine D2 receptors was measured in a cell-based assay. Dopamine D2 receptor cells were seeded in a half a blac... | US Patent US10259786 (2019) BindingDB Entry DOI: 10.7270/Q2377C1M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50001885![]() ((risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | Purchase CHEBI CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars | DrugBank US Patent | n/a | n/a | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a |
LB PHARMACEUTICALS INC. US Patent | Assay Description The ability of Compound 102 to bind dopamine D2 receptors was measured in a cell-based assay. Dopamine D2 receptor cells were seeded in a half a blac... | US Patent US10259786 (2019) BindingDB Entry DOI: 10.7270/Q2377C1M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM313180![]() (4-methylamino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 8.20 | n/a | n/a | n/a | n/a | n/a | n/a |
LB PHARMACEUTICALS INC. US Patent | Assay Description The ability of Compound 102 to bind the dopamine D2 receptor in a membrane preparation was examined. Medium was removed from dopamine D2 receptor cel... | US Patent US10259786 (2019) BindingDB Entry DOI: 10.7270/Q2377C1M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM81790![]() (Amisulpride | CAS_71675-85-9 | NSC_2159 | US101672...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | Purchase CHEBI DrugBank PC cid PC sid UniChem Patents Similars | DrugBank US Patent | n/a | n/a | 8.5 | n/a | n/a | n/a | n/a | n/a | n/a |
LB PHARMACEUTICALS INC. US Patent | Assay Description The ability of Compound 102 to bind the dopamine D2 receptor in a membrane preparation was examined. Medium was removed from dopamine D2 receptor cel... | US Patent US10259786 (2019) BindingDB Entry DOI: 10.7270/Q2377C1M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM313180![]() (4-methylamino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 8.90 | n/a | n/a | n/a | n/a | n/a | n/a |
LB PHARMACEUTICALS INC. US Patent | Assay Description The ability of Compound 102 to bind dopamine D2 receptors was measured in a cell-based assay. Dopamine D2 receptor cells were seeded in a half a blac... | US Patent US10259786 (2019) BindingDB Entry DOI: 10.7270/Q2377C1M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50001885![]() ((risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | Purchase CHEBI CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars | DrugBank US Patent | n/a | n/a | 10.4 | n/a | n/a | n/a | n/a | n/a | n/a |
LB PHARMACEUTICALS INC. US Patent | Assay Description The ability of Compound 102 to bind the dopamine D2 receptor in a membrane preparation was examined. Medium was removed from dopamine D2 receptor cel... | US Patent US10259786 (2019) BindingDB Entry DOI: 10.7270/Q2377C1M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM22869![]() (6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
LB PHARMACEUTICALS INC. US Patent | Assay Description The ability of Compound 102 to bind the dopamine D2 receptor in a membrane preparation was examined. Medium was removed from dopamine D2 receptor cel... | US Patent US10259786 (2019) BindingDB Entry DOI: 10.7270/Q2377C1M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM22869![]() (6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 7.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
LB PHARMACEUTICALS INC. US Patent | Assay Description The ability of Compound 102 to bind dopamine D2 receptors was measured in a cell-based assay. Dopamine D2 receptor cells were seeded in a half a blac... | US Patent US10259786 (2019) BindingDB Entry DOI: 10.7270/Q2377C1M | |||||||||||
More data for this Ligand-Target Pair |