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Patent code US10280166

Compile Data Set for Download or QSAR
Found 126 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384029
PNG
(US10280166, Compound 346)
Show SMILES CC(C)(C)C(=O)Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3ccc(F)s3)c2c1
Show InChI InChI=1S/C27H20FN7OS/c1-27(2,3)26(36)31-16-10-15(12-29-13-16)14-4-5-19-18(11-14)23(35-34-19)25-32-22-17(8-9-30-24(22)33-25)20-6-7-21(28)37-20/h4-13H,1-3H3,(H,31,36)/b25-23-
UniProtKB/SwissProt

GoogleScholar
UniChem
US Patent
n/an/a 0.400n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384033
PNG
(US10280166, Compound 372)
Show SMILES Cc1ccc(s1)-c1ccnc2[nH]c(nc12)-c1n[nH]c2ccc(cc12)-c1cncc(NC(=O)C(C)(C)C)c1
Show InChI InChI=1S/C28H23N7OS/c1-15-5-8-22(37-15)19-9-10-30-25-23(19)32-26(33-25)24-20-12-16(6-7-21(20)34-35-24)17-11-18(14-29-13-17)31-27(36)28(2,3)4/h5-14H,1-4H3,(H,31,36)/b26-24-
UniProtKB/SwissProt

GoogleScholar
UniChem
US Patent
n/an/a 0.600n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384010
PNG
(US10280166, Compound 277)
Show SMILES CCCC(=O)Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3ccsc3)c2c1
Show InChI InChI=1S/C26H19N7OS/c1-2-3-22(34)29-18-10-17(12-27-13-18)15-4-5-21-20(11-15)24(33-32-21)26-30-23-19(16-7-9-35-14-16)6-8-28-25(23)31-26/h4-14H,2-3H2,1H3,(H,29,34)/b26-24-
UniProtKB/SwissProt

GoogleScholar
UniChem
US Patent
n/an/a 1n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383959
PNG
(US10280166, Compound 25)
Show SMILES Fc1cccc(c1)-c1ccnc2[nH]c(nc12)-c1n[nH]c2ccc(cc12)-c1cncc(CN2CCC(F)(F)C2)c1
Show InChI InChI=1S/C29H20F3N7/c30-21-3-1-2-19(11-21)22-6-8-34-27-25(22)35-28(36-27)26-23-12-18(4-5-24(23)37-38-26)20-10-17(13-33-14-20)15-39-9-7-29(31,32)16-39/h1-6,8,10-14H,7,9,15-16H2/b28-26-
UniProtKB/SwissProt

GoogleScholar
UniChem
US Patent
n/an/a<1n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383956
PNG
(US10280166, Compound 19)
Show SMILES Fc1cccc(c1)-c1ccnc2[nH]c(nc12)-c1n[nH]c2ccc(cc12)-c1cncc(NC(=O)C2CC2)c1
Show InChI InChI=1S/C28H18FN7O/c29-19-3-1-2-17(10-19)21-8-9-31-26-24(21)33-27(34-26)25-22-12-16(6-7-23(22)35-36-25)18-11-20(14-30-13-18)32-28(37)15-4-5-15/h1-3,6-15H,4-5H2,(H,32,37)/b27-25-
UniProtKB/SwissProt

GoogleScholar
UniChem
US Patent
n/an/a 1n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383939
PNG
(US10280166, Compound 7)
Show SMILES CN(C)c1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3cccc(F)c3)c2c1
Show InChI InChI=1S/C26H18FN7/c1-34(2)19-11-17(13-28-14-19)15-6-7-22-21(12-15)24(33-32-22)26-30-23-20(8-9-29-25(23)31-26)16-4-3-5-18(27)10-16/h3-14H,1-2H3/b26-24-
UniProtKB/SwissProt

GoogleScholar
UniChem
US Patent
n/an/a<1n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383918
PNG
(US10280166, Compound 1)
Show SMILES CCC(=O)Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3cccc(F)c3)c2c1
Show InChI InChI=1S/C27H18FN7O/c1-2-23(36)31-19-11-17(13-29-14-19)15-6-7-22-21(12-15)25(35-34-22)27-32-24-20(8-9-30-26(24)33-27)16-4-3-5-18(28)10-16/h3-14H,2H2,1H3,(H,31,36)/b27-25-
UniProtKB/SwissProt

GoogleScholar
UniChem
US Patent
n/an/a<1n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383965
PNG
(US10280166, Compound 55)
Show SMILES Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3ccccc3F)c2c1
Show InChI InChI=1S/C24H14FN7/c25-19-4-2-1-3-16(19)17-7-8-28-23-21(17)29-24(30-23)22-18-10-13(5-6-20(18)31-32-22)14-9-15(26)12-27-11-14/h1-12H,26H2/b24-22-
UniProtKB/SwissProt

GoogleScholar
UniChem
US Patent
n/an/a 1.80n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383937
PNG
(US10280166, Compound 2)
Show SMILES CC(C)CC(=O)Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3cccc(F)c3)c2c1
Show InChI InChI=1S/C29H22FN7O/c1-16(2)10-25(38)33-21-12-19(14-31-15-21)17-6-7-24-23(13-17)27(37-36-24)29-34-26-22(8-9-32-28(26)35-29)18-4-3-5-20(30)11-18/h3-9,11-16H,10H2,1-2H3,(H,33,38)/b29-27-
UniProtKB/SwissProt

GoogleScholar
UniChem
US Patent
n/an/a 2n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384020
PNG
(US10280166, Compound 313)
Show SMILES CCC(=O)Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3cccs3)c2c1
Show InChI InChI=1S/C25H17N7OS/c1-2-21(33)28-16-10-15(12-26-13-16)14-5-6-19-18(11-14)23(32-31-19)25-29-22-17(20-4-3-9-34-20)7-8-27-24(22)30-25/h3-13H,2H2,1H3,(H,28,33)/b25-23-
UniProtKB/SwissProt

GoogleScholar
UniChem
US Patent
n/an/a 2n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383963
PNG
(US10280166, Compound 46)
Show SMILES Fc1ccc(cc1)-c1ccnc2[nH]c(nc12)-c1n[nH]c2ccc(cc12)-c1cncc(NC(=O)C2CCC2)c1
Show InChI InChI=1S/C29H20FN7O/c30-20-7-4-16(5-8-20)22-10-11-32-27-25(22)34-28(35-27)26-23-13-18(6-9-24(23)36-37-26)19-12-21(15-31-14-19)33-29(38)17-2-1-3-17/h4-15,17H,1-3H2,(H,33,38)/b28-26-
UniProtKB/SwissProt

GoogleScholar
UniChem
US Patent
n/an/a 2n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383991
PNG
(US10280166, Compound 184)
Show SMILES CC(C)CC(=O)Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-n3cnc(C)c3)c2c1
Show InChI InChI=1S/C27H23N9O/c1-15(2)8-23(37)31-19-9-18(11-28-12-19)17-4-5-21-20(10-17)24(35-34-21)27-32-25-22(6-7-29-26(25)33-27)36-13-16(3)30-14-36/h4-7,9-15H,8H2,1-3H3,(H,31,37)/b27-24-
UniProtKB/SwissProt

GoogleScholar
UniChem
US Patent
n/an/a 2.30n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383946
PNG
(US10280166, Compound 9)
Show SMILES CC(C)C(=O)Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3cccc(F)c3)c2c1
Show InChI InChI=1S/C28H20FN7O/c1-15(2)28(37)32-20-11-18(13-30-14-20)16-6-7-23-22(12-16)25(36-35-23)27-33-24-21(8-9-31-26(24)34-27)17-4-3-5-19(29)10-17/h3-15H,1-2H3,(H,32,37)/b27-25-
UniProtKB/SwissProt

GoogleScholar
UniChem
US Patent
n/an/a 3n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384039
PNG
(US10280166, Compound 433)
Show SMILES CCCC(=O)Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3cc(F)cc(CNS(C)(=O)=O)c3)c2c1
Show InChI InChI=1S/C30H25FN8O3S/c1-3-4-26(40)35-22-12-20(15-32-16-22)18-5-6-25-24(13-18)28(39-38-25)30-36-27-23(7-8-33-29(27)37-30)19-9-17(10-21(31)11-19)14-34-43(2,41)42/h5-13,15-16,34H,3-4,14H2,1-2H3,(H,35,40)/b30-28-
UniProtKB/SwissProt

GoogleScholar
UniChem
US Patent
n/an/a 3n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383972
PNG
(US10280166, Compound 82)
Show SMILES c1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3cccnc3)c2c1
Show InChI InChI=1S/C23H13N7/c1-3-15(12-24-8-1)14-5-6-19-18(11-14)21(30-29-19)23-27-20-17(7-10-26-22(20)28-23)16-4-2-9-25-13-16/h1-13H/b23-21-
UniProtKB/SwissProt

GoogleScholar
UniChem
US Patent
n/an/a 3.5n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383960
PNG
(US10280166, Compound 28)
Show SMILES CC(C)CC(=O)Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3ccc(F)cc3)c2c1
Show InChI InChI=1S/C29H22FN7O/c1-16(2)11-25(38)33-21-12-19(14-31-15-21)18-5-8-24-23(13-18)27(37-36-24)29-34-26-22(9-10-32-28(26)35-29)17-3-6-20(30)7-4-17/h3-10,12-16H,11H2,1-2H3,(H,33,38)/b29-27-
UniProtKB/SwissProt

GoogleScholar
UniChem
US Patent
n/an/a 4n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384032
PNG
(US10280166, Compound 367)
Show SMILES Cc1ccc(s1)-c1ccnc2[nH]c(nc12)-c1n[nH]c2ccc(cc12)-c1cncc(N)c1
Show InChI InChI=1S/C23H15N7S/c1-12-2-5-19(31-12)16-6-7-26-22-20(16)27-23(28-22)21-17-9-13(3-4-18(17)29-30-21)14-8-15(24)11-25-10-14/h2-11H,24H2,1H3/b23-21-
UniProtKB/SwissProt

GoogleScholar
UniChem
US Patent
n/an/a 4.30n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383993
PNG
(US10280166, Compound 202)
Show SMILES Cc1cn(cn1)-c1ccnc2[nH]c(nc12)-c1n[nH]c2ccc(cc12)-c1cncc(NC(=O)C2CCC2)c1
Show InChI InChI=1S/C27H21N9O/c1-15-13-36(14-30-15)22-7-8-29-25-24(22)32-26(33-25)23-20-10-17(5-6-21(20)34-35-23)18-9-19(12-28-11-18)31-27(37)16-3-2-4-16/h5-14,16H,2-4H2,1H3,(H,31,37)/b26-23-
UniProtKB/SwissProt

GoogleScholar
UniChem
US Patent
n/an/a 4.70n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384028
PNG
(US10280166, Compound 340)
Show SMILES CC(C)CC(=O)Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3ccc(F)s3)c2c1
Show InChI InChI=1S/C27H20FN7OS/c1-14(2)9-23(36)31-17-10-16(12-29-13-17)15-3-4-20-19(11-15)25(35-34-20)27-32-24-18(7-8-30-26(24)33-27)21-5-6-22(28)37-21/h3-8,10-14H,9H2,1-2H3,(H,31,36)/b27-25-
UniProtKB/SwissProt

GoogleScholar
UniChem
US Patent
n/an/a 4.90n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384016
PNG
(US10280166, Compound 298)
Show SMILES CC(C)Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3ccoc3)c2c1
Show InChI InChI=1S/C25H19N7O/c1-14(2)28-18-9-17(11-26-12-18)15-3-4-21-20(10-15)23(32-31-21)25-29-22-19(16-6-8-33-13-16)5-7-27-24(22)30-25/h3-14,28H,1-2H3/b25-23-
UniProtKB/SwissProt

GoogleScholar
UniChem
US Patent
n/an/a 5n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384057
PNG
(US10280166, Compound 1875)
Show SMILES Fc1cccc(c1)-c1ccnc2[nH]c(nc12)-c1n[nH]c2ccc(cc12)-c1cn[nH]c1
Show InChI InChI=1S/C22H14FN7/c23-15-3-1-2-13(8-15)16-6-7-24-21-19(16)27-22(28-21)20-17-9-12(14-10-25-26-11-14)4-5-18(17)29-30-20/h1-11H,(H,25,26)(H,29,30)(H,24,27,28)
UniProtKB/SwissProt

GoogleScholar
UniChem
US Patent
n/an/a 5n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384007
PNG
(US10280166, Compound 269)
Show SMILES CC(C)C(=O)Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3ccsc3)c2c1
Show InChI InChI=1S/C26H19N7OS/c1-14(2)26(34)29-18-9-17(11-27-12-18)15-3-4-21-20(10-15)23(33-32-21)25-30-22-19(16-6-8-35-13-16)5-7-28-24(22)31-25/h3-14H,1-2H3,(H,29,34)/b25-23-
UniProtKB/SwissProt

GoogleScholar
UniChem
US Patent
n/an/a 5.10n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384015
PNG
(US10280166, Compound 295)
Show SMILES CC(C)C(=O)Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3ccoc3)c2c1
Show InChI InChI=1S/C26H19N7O2/c1-14(2)26(34)29-18-9-17(11-27-12-18)15-3-4-21-20(10-15)23(33-32-21)25-30-22-19(16-6-8-35-13-16)5-7-28-24(22)31-25/h3-14H,1-2H3,(H,29,34)/b25-23-
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n/an/a 5.10n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384011
PNG
(US10280166, Compound 279)
Show SMILES O=C(Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3ccsc3)c2c1)C1CC1
Show InChI InChI=1S/C26H17N7OS/c34-26(14-1-2-14)29-18-9-17(11-27-12-18)15-3-4-21-20(10-15)23(33-32-21)25-30-22-19(16-6-8-35-13-16)5-7-28-24(22)31-25/h3-14H,1-2H2,(H,29,34)/b25-23-
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n/an/a 5.20n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383971
PNG
(US10280166, Compound 81)
Show SMILES Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3cccnc3)c2c1
Show InChI InChI=1S/C23H14N8/c24-16-8-15(11-26-12-16)13-3-4-19-18(9-13)21(31-30-19)23-28-20-17(5-7-27-22(20)29-23)14-2-1-6-25-10-14/h1-12H,24H2/b23-21-
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n/an/a 5.80n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384041
PNG
(US10280166, Compound 442)
Show SMILES CS(=O)(=O)NCc1cc(F)cc(c1)-c1ccnc2[nH]c(nc12)-c1n[nH]c2ccc(cc12)-c1cncnc1
Show InChI InChI=1S/C25H17FN8O2S/c1-37(35,36)30-10-14-6-16(8-18(26)7-14)19-4-5-29-24-22(19)31-25(32-24)23-20-9-15(2-3-21(20)33-34-23)17-11-27-13-28-12-17/h2-9,11-13,30H,10H2,1H3/b25-23-
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n/an/a 5.80n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383967
PNG
(US10280166, Compound 61)
Show SMILES CC(C)C(=O)Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3ccccc3F)c2c1
Show InChI InChI=1S/C28H20FN7O/c1-15(2)28(37)32-18-11-17(13-30-14-18)16-7-8-23-21(12-16)25(36-35-23)27-33-24-20(9-10-31-26(24)34-27)19-5-3-4-6-22(19)29/h3-15H,1-2H3,(H,32,37)/b27-25-
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n/an/a 6n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384017
PNG
(US10280166, Compound 304)
Show SMILES CCCCC(=O)Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3ccoc3)c2c1
Show InChI InChI=1S/C27H21N7O2/c1-2-3-4-23(35)30-19-11-18(13-28-14-19)16-5-6-22-21(12-16)25(34-33-22)27-31-24-20(17-8-10-36-15-17)7-9-29-26(24)32-27/h5-15H,2-4H2,1H3,(H,30,35)/b27-25-
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n/an/a 6n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384037
PNG
(US10280166, Compound 421)
Show SMILES Cc1ccncc1-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3cc(F)cc(CNS(C)(=O)=O)c3)c2c1
Show InChI InChI=1S/C27H20FN7O2S/c1-15-5-7-29-14-22(15)17-3-4-23-21(12-17)25(35-34-23)27-32-24-20(6-8-30-26(24)33-27)18-9-16(10-19(28)11-18)13-31-38(2,36)37/h3-12,14,31H,13H2,1-2H3/b27-25-
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n/an/a 6.10n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384026
PNG
(US10280166, Compound 333)
Show SMILES O=C(Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3cccs3)c2c1)C1CCCC1
Show InChI InChI=1S/C28H21N7OS/c36-28(16-4-1-2-5-16)31-19-12-18(14-29-15-19)17-7-8-22-21(13-17)25(35-34-22)27-32-24-20(23-6-3-11-37-23)9-10-30-26(24)33-27/h3,6-16H,1-2,4-5H2,(H,31,36)/b27-25-
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n/an/a 6.30n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384034
PNG
(US10280166, Compound 373)
Show SMILES CC(C)C(=O)Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3ccc(C)s3)c2c1
Show InChI InChI=1S/C27H21N7OS/c1-14(2)27(35)30-18-10-17(12-28-13-18)16-5-6-21-20(11-16)24(34-33-21)26-31-23-19(8-9-29-25(23)32-26)22-7-4-15(3)36-22/h4-14H,1-3H3,(H,30,35)/b26-24-
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n/an/a 6.40n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384006
PNG
(US10280166, Compound 268)
Show SMILES CC(C)(C)C(=O)Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3ccsc3)c2c1
Show InChI InChI=1S/C27H21N7OS/c1-27(2,3)26(35)30-18-10-17(12-28-13-18)15-4-5-21-20(11-15)23(34-33-21)25-31-22-19(16-7-9-36-14-16)6-8-29-24(22)32-25/h4-14H,1-3H3,(H,30,35)/b25-23-
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n/an/a 6.5n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384018
PNG
(US10280166, Compound 306)
Show SMILES O=C(Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3ccoc3)c2c1)C1CCC1
Show InChI InChI=1S/C27H19N7O2/c35-27(15-2-1-3-15)30-19-10-18(12-28-13-19)16-4-5-22-21(11-16)24(34-33-22)26-31-23-20(17-7-9-36-14-17)6-8-29-25(23)32-26/h4-15H,1-3H2,(H,30,35)/b26-24-
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n/an/a 6.70n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383973
PNG
(US10280166, Compound 87)
Show SMILES CC(C)C(=O)Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3cccnc3)c2c1
Show InChI InChI=1S/C27H20N8O/c1-15(2)27(36)31-19-10-18(13-29-14-19)16-5-6-22-21(11-16)24(35-34-22)26-32-23-20(7-9-30-25(23)33-26)17-4-3-8-28-12-17/h3-15H,1-2H3,(H,31,36)/b26-24-
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n/an/a 6.80n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384031
PNG
(US10280166, Compound 358)
Show SMILES Fc1ccc(s1)-c1ccnc2[nH]c(nc12)-c1n[nH]c2ccc(cc12)-c1cncc(NC(=O)C2CCC2)c1
Show InChI InChI=1S/C27H18FN7OS/c28-22-7-6-21(37-22)18-8-9-30-25-23(18)32-26(33-25)24-19-11-15(4-5-20(19)34-35-24)16-10-17(13-29-12-16)31-27(36)14-2-1-3-14/h4-14H,1-3H2,(H,31,36)/b26-24-
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n/an/a 6.90n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383992
PNG
(US10280166, Compound 190)
Show SMILES Cc1cn(cn1)-c1ccnc2[nH]c(nc12)-c1n[nH]c2ccc(cc12)-c1cncc(NC(=O)C(C)(C)C)c1
Show InChI InChI=1S/C27H23N9O/c1-15-13-36(14-30-15)21-7-8-29-24-23(21)32-25(33-24)22-19-10-16(5-6-20(19)34-35-22)17-9-18(12-28-11-17)31-26(37)27(2,3)4/h5-14H,1-4H3,(H,31,37)/b25-22-
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n/an/a 7.40n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383983
PNG
(US10280166, Compound 148)
Show SMILES CCCCC(=O)Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3ccccn3)c2c1
Show InChI InChI=1S/C28H22N8O/c1-2-3-7-24(37)32-19-13-18(15-29-16-19)17-8-9-23-21(14-17)26(36-35-23)28-33-25-20(10-12-31-27(25)34-28)22-6-4-5-11-30-22/h4-6,8-16H,2-3,7H2,1H3,(H,32,37)/b28-26-
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n/an/a 8.10n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384009
PNG
(US10280166, Compound 271)
Show SMILES O=C(Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3ccsc3)c2c1)c1ccccc1
Show InChI InChI=1S/C29H17N7OS/c37-29(17-4-2-1-3-5-17)32-21-12-20(14-30-15-21)18-6-7-24-23(13-18)26(36-35-24)28-33-25-22(19-9-11-38-16-19)8-10-31-27(25)34-28/h1-16H,(H,32,37)/b28-26-
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n/an/a 8.40n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384022
PNG
(US10280166, Compound 320)
Show SMILES CC(C)(C)C(=O)Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3cccs3)c2c1
Show InChI InChI=1S/C27H21N7OS/c1-27(2,3)26(35)30-17-11-16(13-28-14-17)15-6-7-20-19(12-15)23(34-33-20)25-31-22-18(21-5-4-10-36-21)8-9-29-24(22)32-25/h4-14H,1-3H3,(H,30,35)/b25-23-
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n/an/a 8.80n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383958
PNG
(US10280166, Compound 21)
Show SMILES Fc1cccc(c1)-c1ccnc2[nH]c(nc12)-c1n[nH]c2ccc(cc12)-c1cncc(NC(=O)C2CCCC2)c1
Show InChI InChI=1S/C30H22FN7O/c31-21-7-3-6-19(12-21)23-10-11-33-28-26(23)35-29(36-28)27-24-14-18(8-9-25(24)37-38-27)20-13-22(16-32-15-20)34-30(39)17-4-1-2-5-17/h3,6-17H,1-2,4-5H2,(H,34,39)/b29-27-
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n/an/a 9.10n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384005
PNG
(US10280166, Compound 265)
Show SMILES Cc1ccncc1-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3ccsc3)c2c1
Show InChI InChI=1S/C23H14N6S/c1-13-4-7-24-11-18(13)14-2-3-19-17(10-14)21(29-28-19)23-26-20-16(15-6-9-30-12-15)5-8-25-22(20)27-23/h2-12H,1H3/b23-21-
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n/an/a 9.40n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384012
PNG
(US10280166, Compound 281)
Show SMILES O=C(Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3ccsc3)c2c1)C1CCCC1
Show InChI InChI=1S/C28H21N7OS/c36-28(16-3-1-2-4-16)31-20-11-19(13-29-14-20)17-5-6-23-22(12-17)25(35-34-23)27-32-24-21(18-8-10-37-15-18)7-9-30-26(24)33-27/h5-16H,1-4H2,(H,31,36)/b27-25-
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n/an/a 9.80n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384067
PNG
(US10280166, Compound 1885)
Show SMILES Oc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3cccc(F)c3)c2c1
Show InChI InChI=1S/C24H13FN6O/c25-16-3-1-2-14(8-16)18-6-7-27-23-21(18)28-24(29-23)22-19-10-13(4-5-20(19)30-31-22)15-9-17(32)12-26-11-15/h1-12,32H/b24-22-
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n/an/a 11n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383969
PNG
(US10280166, Compound 71)
Show SMILES Fc1ccccc1-c1ccnc2[nH]c(nc12)-c1n[nH]c2ccc(cc12)-c1cncc(NC(=O)C2CC2)c1
Show InChI InChI=1S/C28H18FN7O/c29-22-4-2-1-3-19(22)20-9-10-31-26-24(20)33-27(34-26)25-21-12-16(7-8-23(21)35-36-25)17-11-18(14-30-13-17)32-28(37)15-5-6-15/h1-4,7-15H,5-6H2,(H,32,37)/b27-25-
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n/an/a 11.1n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384044
PNG
(US10280166, Compound 460)
Show SMILES CCCCC(=O)Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3cc(F)cc(NCCN(C)C)c3)c2c1
Show InChI InChI=1S/C33H32FN9O/c1-4-5-6-29(44)38-25-15-22(18-35-19-25)20-7-8-28-27(16-20)31(42-41-28)33-39-30-26(9-10-37-32(30)40-33)21-13-23(34)17-24(14-21)36-11-12-43(2)3/h7-10,13-19,36H,4-6,11-12H2,1-3H3,(H,38,44)/b33-31-
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n/an/a 11.6n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383974
PNG
(US10280166, Compound 90)
Show SMILES CC(C)Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3cccnc3)c2c1
Show InChI InChI=1S/C26H20N8/c1-15(2)30-19-10-18(13-28-14-19)16-5-6-22-21(11-16)24(34-33-22)26-31-23-20(7-9-29-25(23)32-26)17-4-3-8-27-12-17/h3-15,30H,1-2H3/b26-24-
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n/an/a 12n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383970
PNG
(US10280166, Compound 73)
Show SMILES Fc1ccccc1-c1ccnc2[nH]c(nc12)-c1n[nH]c2ccc(cc12)-c1cncc(NC(=O)C2CCCC2)c1
Show InChI InChI=1S/C30H22FN7O/c31-24-8-4-3-7-21(24)22-11-12-33-28-26(22)35-29(36-28)27-23-14-18(9-10-25(23)37-38-27)19-13-20(16-32-15-19)34-30(39)17-5-1-2-6-17/h3-4,7-17H,1-2,5-6H2,(H,34,39)/b29-27-
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n/an/a 13n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384030
PNG
(US10280166, Compound 352)
Show SMILES Fc1ccc(s1)-c1ccnc2[nH]c(nc12)-c1n[nH]c2ccc(cc12)-c1cncc(CN2CCCC2)c1
Show InChI InChI=1S/C27H20FN7S/c28-23-6-5-22(36-23)19-7-8-30-26-24(19)31-27(32-26)25-20-12-17(3-4-21(20)33-34-25)18-11-16(13-29-14-18)15-35-9-1-2-10-35/h3-8,11-14H,1-2,9-10,15H2/b27-25-
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n/an/a 13.2n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383982
PNG
(US10280166, Compound 141)
Show SMILES O=C(Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3ccccn3)c2c1)c1ccccc1
Show InChI InChI=1S/C30H18N8O/c39-30(18-6-2-1-3-7-18)34-21-14-20(16-31-17-21)19-9-10-25-23(15-19)27(38-37-25)29-35-26-22(11-13-33-28(26)36-29)24-8-4-5-12-32-24/h1-17H,(H,34,39)/b29-27-
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n/an/a 13.7n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383977
PNG
(US10280166, Compound 109)
Show SMILES Cc1ccncc1-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3ccncc3)c2c1
Show InChI InChI=1S/C24H15N7/c1-14-4-8-26-13-19(14)16-2-3-20-18(12-16)22(31-30-20)24-28-21-17(7-11-27-23(21)29-24)15-5-9-25-10-6-15/h2-13H,1H3/b24-22-
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n/an/a 13.7n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383984
PNG
(US10280166, Compound 150)
Show SMILES O=C(Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3ccccn3)c2c1)C1CCC1
Show InChI InChI=1S/C28H20N8O/c37-28(16-4-3-5-16)32-19-12-18(14-29-15-19)17-7-8-23-21(13-17)25(36-35-23)27-33-24-20(9-11-31-26(24)34-27)22-6-1-2-10-30-22/h1-2,6-16H,3-5H2,(H,32,37)/b27-25-
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n/an/a 15n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383986
PNG
(US10280166, Compound 157)
Show SMILES CCC(=O)Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)N3CCCCC3)c2c1
Show InChI InChI=1S/C26H24N8O/c1-2-22(35)29-18-12-17(14-27-15-18)16-6-7-20-19(13-16)23(33-32-20)26-30-24-21(8-9-28-25(24)31-26)34-10-4-3-5-11-34/h6-9,12-15H,2-5,10-11H2,1H3,(H,29,35)/b26-23-
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n/an/a 15n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384027
PNG
(US10280166, Compound 337)
Show SMILES CCC(=O)Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3ccc(F)s3)c2c1
Show InChI InChI=1S/C25H16FN7OS/c1-2-21(34)29-15-9-14(11-27-12-15)13-3-4-18-17(10-13)23(33-32-18)25-30-22-16(7-8-28-24(22)31-25)19-5-6-20(26)35-19/h3-12H,2H2,1H3,(H,29,34)/b25-23-
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n/an/a 15n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384008
PNG
(US10280166, Compound 270)
Show SMILES O=C(Cc1ccccc1)Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3ccsc3)c2c1
Show InChI InChI=1S/C30H19N7OS/c38-26(12-18-4-2-1-3-5-18)33-22-13-21(15-31-16-22)19-6-7-25-24(14-19)28(37-36-25)30-34-27-23(20-9-11-39-17-20)8-10-32-29(27)35-30/h1-11,13-17H,12H2,(H,33,38)/b30-28-
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n/an/a 16.3n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383961
PNG
(US10280166, Compound 34)
Show SMILES CC(C)(C)C(=O)Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3ccc(F)cc3)c2c1
Show InChI InChI=1S/C29H22FN7O/c1-29(2,3)28(38)33-20-12-18(14-31-15-20)17-6-9-23-22(13-17)25(37-36-23)27-34-24-21(10-11-32-26(24)35-27)16-4-7-19(30)8-5-16/h4-15H,1-3H3,(H,33,38)/b27-25-
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n/an/a 19n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384038
PNG
(US10280166, Compound 427)
Show SMILES CS(=O)(=O)NCc1cc(F)cc(c1)-c1ccnc2[nH]c(nc12)-c1n[nH]c2ccc(cc12)-c1cncc(NC(=O)c2ccccc2)c1
Show InChI InChI=1S/C33H23FN8O3S/c1-46(44,45)37-16-19-11-22(13-24(34)12-19)26-9-10-36-31-29(26)39-32(40-31)30-27-15-21(7-8-28(27)41-42-30)23-14-25(18-35-17-23)38-33(43)20-5-3-2-4-6-20/h2-15,17-18,37H,16H2,1H3,(H,38,43)/b32-30-
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n/an/a 19.2n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384036
PNG
(US10280166, Compound 385)
Show SMILES Cc1ccc(s1)-c1ccnc2[nH]c(nc12)-c1n[nH]c2ccc(cc12)-c1cncc(NC(=O)C2CCCC2)c1
Show InChI InChI=1S/C29H23N7OS/c1-16-6-9-24(38-16)21-10-11-31-27-25(21)33-28(34-27)26-22-13-18(7-8-23(22)35-36-26)19-12-20(15-30-14-19)32-29(37)17-4-2-3-5-17/h6-15,17H,2-5H2,1H3,(H,32,37)/b28-26-
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n/an/a 19.2n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384076
PNG
(US10280166, Compound 2330)
Show SMILES COc1cc(F)cc(c1)-c1ccnc2[nH]c(nc12)-c1n[nH]c2ccc(cc12)-c1cncc(NC(=O)CC(C)C)c1
Show InChI InChI=1S/C30H24FN7O2/c1-16(2)8-26(39)34-21-10-19(14-32-15-21)17-4-5-25-24(12-17)28(38-37-25)30-35-27-23(6-7-33-29(27)36-30)18-9-20(31)13-22(11-18)40-3/h4-7,9-16H,8H2,1-3H3,(H,34,39)/b30-28-
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n/an/a 20n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383964
PNG
(US10280166, Compound 52)
Show SMILES Fc1ccc(cc1)-c1ccnc2[nH]c(nc12)-c1n[nH]c2ccc(cc12)-c1cncnc1
Show InChI InChI=1S/C23H12FN7/c24-16-4-1-13(2-5-16)17-7-8-27-22-20(17)28-23(29-22)21-18-9-14(3-6-19(18)30-31-21)15-10-25-12-26-11-15/h1-12H/b23-21-
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n/an/a 25.6n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383999
PNG
(US10280166, Compound 238)
Show SMILES c1cncc(c1)-c1ccc2[nH]nc(-c3nc4cccnc4[nH]3)c2c1
Show InChI InChI=1S/C18H10N6/c1-3-12(10-19-7-1)11-5-6-14-13(9-11)16(24-23-14)18-21-15-4-2-8-20-17(15)22-18/h1-10H/b18-16-
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n/an/a 28.8n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383980
PNG
(US10280166, Compound 126)
Show SMILES O=C(Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3ccncc3)c2c1)C1CCCCC1
Show InChI InChI=1S/C30H24N8O/c39-30(19-4-2-1-3-5-19)34-22-14-21(16-32-17-22)20-6-7-25-24(15-20)27(38-37-25)29-35-26-23(10-13-33-28(26)36-29)18-8-11-31-12-9-18/h6-17,19H,1-5H2,(H,34,39)/b29-27-
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n/an/a 30.7n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383966
PNG
(US10280166, Compound 59)
Show SMILES CN(C)c1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3ccccc3F)c2c1
Show InChI InChI=1S/C26H18FN7/c1-34(2)17-11-16(13-28-14-17)15-7-8-22-20(12-15)24(33-32-22)26-30-23-19(9-10-29-25(23)31-26)18-5-3-4-6-21(18)27/h3-14H,1-2H3/b26-24-
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n/an/a 31.9n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384025
PNG
(US10280166, Compound 331)
Show SMILES O=C(Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3cccs3)c2c1)C1CC1
Show InChI InChI=1S/C26H17N7OS/c34-26(14-3-4-14)29-17-10-16(12-27-13-17)15-5-6-20-19(11-15)23(33-32-20)25-30-22-18(21-2-1-9-35-21)7-8-28-24(22)31-25/h1-2,5-14H,3-4H2,(H,29,34)/b25-23-
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n/an/a 34.7n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383979
PNG
(US10280166, Compound 121)
Show SMILES CCCC(=O)Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3ccncc3)c2c1
Show InChI InChI=1S/C27H20N8O/c1-2-3-23(36)31-19-12-18(14-29-15-19)17-4-5-22-21(13-17)25(35-34-22)27-32-24-20(8-11-30-26(24)33-27)16-6-9-28-10-7-16/h4-15H,2-3H2,1H3,(H,31,36)/b27-25-
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n/an/a 35n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384072
PNG
(US10280166, Compound 1890)
Show SMILES Fc1cccc(c1)-c1ccnc2[nH]c(nc12)-c1n[nH]c2ccc(cc12)-c1cnccn1
Show InChI InChI=1S/C23H12FN7/c24-15-3-1-2-13(10-15)16-6-7-27-22-20(16)28-23(29-22)21-17-11-14(4-5-18(17)30-31-21)19-12-25-8-9-26-19/h1-12H/b23-21-
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n/an/a 39n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384023
PNG
(US10280166, Compound 321)
Show SMILES CC(C)C(=O)Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3cccs3)c2c1
Show InChI InChI=1S/C26H19N7OS/c1-14(2)26(34)29-17-10-16(12-27-13-17)15-5-6-20-19(11-15)23(33-32-20)25-30-22-18(21-4-3-9-35-21)7-8-28-24(22)31-25/h3-14H,1-2H3,(H,29,34)/b25-23-
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n/an/a 41.1n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384014
PNG
(US10280166, Compound 292)
Show SMILES CCNCc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3ccoc3)c2c1
Show InChI InChI=1S/C25H19N7O/c1-2-26-11-15-9-18(13-27-12-15)16-3-4-21-20(10-16)23(32-31-21)25-29-22-19(17-6-8-33-14-17)5-7-28-24(22)30-25/h3-10,12-14,26H,2,11H2,1H3/b25-23-
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n/an/a 47.7n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384043
PNG
(US10280166, Compound 454)
Show SMILES CC(C)Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3cc(F)cc(NCCN(C)C)c3)c2c1
Show InChI InChI=1S/C31H30FN9/c1-18(2)36-24-13-21(16-33-17-24)19-5-6-27-26(14-19)29(40-39-27)31-37-28-25(7-8-35-30(28)38-31)20-11-22(32)15-23(12-20)34-9-10-41(3)4/h5-8,11-18,34,36H,9-10H2,1-4H3/b31-29-
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n/an/a 51.7n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383968
PNG
(US10280166, Compound 68)
Show SMILES CC(C)(C)CC(=O)Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3ccccc3F)c2c1
Show InChI InChI=1S/C30H24FN7O/c1-30(2,3)14-25(39)34-19-12-18(15-32-16-19)17-8-9-24-22(13-17)27(38-37-24)29-35-26-21(10-11-33-28(26)36-29)20-6-4-5-7-23(20)31/h4-13,15-16H,14H2,1-3H3,(H,34,39)/b29-27-
UniProtKB/SwissProt

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n/an/a 52n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383978
PNG
(US10280166, Compound 114)
Show SMILES O=C(Cc1ccccc1)Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3ccncc3)c2c1
Show InChI InChI=1S/C31H20N8O/c40-27(14-19-4-2-1-3-5-19)35-23-15-22(17-33-18-23)21-6-7-26-25(16-21)29(39-38-26)31-36-28-24(10-13-34-30(28)37-31)20-8-11-32-12-9-20/h1-13,15-18H,14H2,(H,35,40)/b31-29-
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n/an/a 54n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384075
PNG
(US10280166, Compound 2286)
Show SMILES CC(C)CC(=O)Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3cc(O)cc(F)c3)c2c1
Show InChI InChI=1S/C29H22FN7O2/c1-15(2)7-25(39)33-20-9-18(13-31-14-20)16-3-4-24-23(11-16)27(37-36-24)29-34-26-22(5-6-32-28(26)35-29)17-8-19(30)12-21(38)10-17/h3-6,8-15,38H,7H2,1-2H3,(H,33,39)/b29-27-
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n/an/a 55n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384058
PNG
(US10280166, Compound 1876)
Show SMILES Cn1cc(cn1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3cccc(F)c3)c2c1
Show InChI InChI=1S/C23H14FN7/c1-31-12-15(11-26-31)13-5-6-19-18(10-13)21(30-29-19)23-27-20-17(7-8-25-22(20)28-23)14-3-2-4-16(24)9-14/h2-12H,1H3/b23-21-
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n/an/a 61n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384021
PNG
(US10280166, Compound 319)
Show SMILES CN(C)c1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3cccs3)c2c1
Show InChI InChI=1S/C24H17N7S/c1-31(2)16-10-15(12-25-13-16)14-5-6-19-18(11-14)22(30-29-19)24-27-21-17(20-4-3-9-32-20)7-8-26-23(21)28-24/h3-13H,1-2H3/b24-22-
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n/an/a 62.8n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384063
PNG
(US10280166, Compound 1881)
Show SMILES Fc1cccc(c1)-c1ccnc2[nH]c(nc12)-c1n[nH]c2ccc(cc12)-c1cncc(NC(=O)CC2CCNCC2)c1
Show InChI InChI=1S/C31H25FN8O/c32-22-3-1-2-20(13-22)24-8-11-35-30-28(24)37-31(38-30)29-25-15-19(4-5-26(25)39-40-29)21-14-23(17-34-16-21)36-27(41)12-18-6-9-33-10-7-18/h1-5,8,11,13-18,33H,6-7,9-10,12H2,(H,36,41)/b31-29-
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n/an/a 65n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383994
PNG
(US10280166, Compound 211)
Show SMILES CN1CCN(CC1)c1ccnc2[nH]c(nc12)-c1n[nH]c2ccc(cc12)-c1cncc(N)c1
Show InChI InChI=1S/C23H21N9/c1-31-6-8-32(9-7-31)19-4-5-26-22-21(19)27-23(28-22)20-17-11-14(2-3-18(17)29-30-20)15-10-16(24)13-25-12-15/h2-5,10-13H,6-9,24H2,1H3/b23-20-
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n/an/a 66.3n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384004
PNG
(US10280166, Compound 256)
Show SMILES O=C(Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4cccnc4[nH]3)c2c1)C1CCCCC1
Show InChI InChI=1S/C25H21N7O/c33-25(15-5-2-1-3-6-15)28-18-11-17(13-26-14-18)16-8-9-20-19(12-16)22(32-31-20)24-29-21-7-4-10-27-23(21)30-24/h4,7-15H,1-3,5-6H2,(H,28,33)/b24-22-
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n/an/a 66.3n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384048
PNG
(US10280166, Compound 897)
Show SMILES CN(C)Cc1cncc(c1)-c1cc(F)c2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3cc(F)cc(CNS(C)(=O)=O)c3)c2c1
Show InChI InChI=1S/C29H24F2N8O2S/c1-39(2)15-17-7-20(14-32-12-17)18-10-23-25(24(31)11-18)37-38-27(23)29-35-26-22(4-5-33-28(26)36-29)19-6-16(8-21(30)9-19)13-34-42(3,40)41/h4-12,14,34H,13,15H2,1-3H3/b29-27-
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n/an/a 74n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384035
PNG
(US10280166, Compound 379)
Show SMILES Cc1ccc(s1)-c1ccnc2[nH]c(nc12)-c1n[nH]c2ccc(cc12)-c1cncc(CN2CCCCC2)c1
Show InChI InChI=1S/C29H25N7S/c1-18-5-8-25(37-18)22-9-10-31-28-26(22)32-29(33-28)27-23-14-20(6-7-24(23)34-35-27)21-13-19(15-30-16-21)17-36-11-3-2-4-12-36/h5-10,13-16H,2-4,11-12,17H2,1H3/b29-27-
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n/an/a 76n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384002
PNG
(US10280166, Compound 247)
Show SMILES CN(C)Cc1cncc(c1)-c1ccc2[nH]nc(-c3nc4cccnc4[nH]3)c2c1
Show InChI InChI=1S/C21H17N7/c1-28(2)12-13-8-15(11-22-10-13)14-5-6-17-16(9-14)19(27-26-17)21-24-18-4-3-7-23-20(18)25-21/h3-11H,12H2,1-2H3/b21-19-
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n/an/a 77n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384077
PNG
(US10280166, Compound 2373)
Show SMILES CN(C)CC(=O)Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3cccc(F)c3)c2c1
Show InChI InChI=1S/C28H21FN8O/c1-37(2)15-24(38)32-20-11-18(13-30-14-20)16-6-7-23-22(12-16)26(36-35-23)28-33-25-21(8-9-31-27(25)34-28)17-4-3-5-19(29)10-17/h3-14H,15H2,1-2H3,(H,32,38)/b28-26-
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n/an/a 91n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383989
PNG
(US10280166, Compound 175)
Show SMILES O=C(Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)N3CCCCC3)c2c1)C1CC1
Show InChI InChI=1S/C27H24N8O/c36-27(16-4-5-16)30-19-12-18(14-28-15-19)17-6-7-21-20(13-17)23(34-33-21)26-31-24-22(8-9-29-25(24)32-26)35-10-2-1-3-11-35/h6-9,12-16H,1-5,10-11H2,(H,30,36)/b26-23-
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n/an/a 99.3n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383953
PNG
(US10280166, Compound 13)
Show SMILES CN(C)Cc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3cccc(F)c3)c2c1
Show InChI InChI=1S/C27H20FN7/c1-35(2)15-16-10-19(14-29-13-16)17-6-7-23-22(12-17)25(34-33-23)27-31-24-21(8-9-30-26(24)32-27)18-4-3-5-20(28)11-18/h3-14H,15H2,1-2H3/b27-25-
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n/an/a 116n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383987
PNG
(US10280166, Compound 163)
Show SMILES CN(C)c1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)N3CCCCC3)c2c1
Show InChI InChI=1S/C25H24N8/c1-32(2)18-12-17(14-26-15-18)16-6-7-20-19(13-16)22(31-30-20)25-28-23-21(8-9-27-24(23)29-25)33-10-4-3-5-11-33/h6-9,12-15H,3-5,10-11H2,1-2H3/b25-22-
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n/an/a 122n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384003
PNG
(US10280166, Compound 250)
Show SMILES CC(C)(C)CC(=O)Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4cccnc4[nH]3)c2c1
Show InChI InChI=1S/C24H21N7O/c1-24(2,3)11-20(32)27-16-9-15(12-25-13-16)14-6-7-18-17(10-14)21(31-30-18)23-28-19-5-4-8-26-22(19)29-23/h4-10,12-13H,11H2,1-3H3,(H,27,32)/b23-21-
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n/an/a 124n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384013
PNG
(US10280166, Compound 283)
Show SMILES C(NCc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3ccsc3)c2c1)c1ccccc1
Show InChI InChI=1S/C30H21N7S/c1-2-4-19(5-3-1)14-31-15-20-12-23(17-32-16-20)21-6-7-26-25(13-21)28(37-36-26)30-34-27-24(22-9-11-38-18-22)8-10-33-29(27)35-30/h1-13,16-18,31H,14-15H2/b30-28-
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n/an/a 137n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384046
PNG
(US10280166, Compound 481)
Show SMILES CN(C)Cc1cncc(c1)-c1cc(F)c2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3cccc(F)c3)c2c1
Show InChI InChI=1S/C27H19F2N7/c1-36(2)14-15-8-18(13-30-12-15)17-10-21-23(22(29)11-17)34-35-25(21)27-32-24-20(6-7-31-26(24)33-27)16-4-3-5-19(28)9-16/h3-13H,14H2,1-2H3/b27-25-
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n/an/a 155n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383995
PNG
(US10280166, Compound 217)
Show SMILES CC(C)C(=O)Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)N3CCN(C)CC3)c2c1
Show InChI InChI=1S/C27H27N9O/c1-16(2)27(37)30-19-12-18(14-28-15-19)17-4-5-21-20(13-17)23(34-33-21)26-31-24-22(6-7-29-25(24)32-26)36-10-8-35(3)9-11-36/h4-7,12-16H,8-11H2,1-3H3,(H,30,37)/b26-23-
UniProtKB/SwissProt

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n/an/a 173n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384073
PNG
(US10280166, Compound 2198)
Show SMILES CC(C)CC(=O)Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3cc(F)cc(OCCN(C)C)c3)c2c1
Show InChI InChI=1S/C33H31FN8O2/c1-19(2)11-29(43)37-24-13-22(17-35-18-24)20-5-6-28-27(15-20)31(41-40-28)33-38-30-26(7-8-36-32(30)39-33)21-12-23(34)16-25(14-21)44-10-9-42(3)4/h5-8,12-19H,9-11H2,1-4H3,(H,37,43)/b33-31-
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n/an/a 180n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384042
PNG
(US10280166, Compound 448)
Show SMILES CCNCc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3cc(F)cc(NCCN(C)C)c3)c2c1
Show InChI InChI=1S/C31H30FN9/c1-4-33-16-19-11-22(18-34-17-19)20-5-6-27-26(14-20)29(40-39-27)31-37-28-25(7-8-36-30(28)38-31)21-12-23(32)15-24(13-21)35-9-10-41(2)3/h5-8,11-15,17-18,33,35H,4,9-10,16H2,1-3H3/b31-29-
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n/an/a 203n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384060
PNG
(US10280166, Compound 1878)
Show SMILES NC1CN(C1)c1cncc(n1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3cccc(F)c3)c2c1
Show InChI InChI=1S/C26H18FN9/c27-16-3-1-2-14(8-16)18-6-7-30-25-23(18)32-26(33-25)24-19-9-15(4-5-20(19)34-35-24)21-10-29-11-22(31-21)36-12-17(28)13-36/h1-11,17H,12-13,28H2/b26-24-
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n/an/a 215n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383997
PNG
(US10280166, Compound 229)
Show SMILES CN1CCN(CC1)c1ccnc2[nH]c(nc12)-c1n[nH]c2ccc(cc12)-c1cncc(NC(=O)C2CCCC2)c1
Show InChI InChI=1S/C29H29N9O/c1-37-10-12-38(13-11-37)24-8-9-31-27-26(24)33-28(34-27)25-22-15-19(6-7-23(22)35-36-25)20-14-21(17-30-16-20)32-29(39)18-4-2-3-5-18/h6-9,14-18H,2-5,10-13H2,1H3,(H,32,39)/b28-25-
UniProtKB/SwissProt

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n/an/a 284n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384001
PNG
(US10280166, Compound 244)
Show SMILES O=C(Cc1ccccc1)Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4cccnc4[nH]3)c2c1
Show InChI InChI=1S/C26H17N7O/c34-23(11-16-5-2-1-3-6-16)29-19-12-18(14-27-15-19)17-8-9-21-20(13-17)24(33-32-21)26-30-22-7-4-10-28-25(22)31-26/h1-10,12-15H,11H2,(H,29,34)/b26-24-
UniProtKB/SwissProt

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n/an/a 352n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384040
PNG
(US10280166, Compound 439)
Show SMILES CS(=O)(=O)NCc1cc(F)cc(c1)-c1ccnc2[nH]c(nc12)-c1n[nH]c2ccc(cc12)-c1cncc(CNCc2ccccc2)c1
Show InChI InChI=1S/C34H27FN8O2S/c1-46(44,45)39-19-22-11-25(14-27(35)13-22)28-9-10-38-33-31(28)40-34(41-33)32-29-15-24(7-8-30(29)42-43-32)26-12-23(18-37-20-26)17-36-16-21-5-3-2-4-6-21/h2-15,18,20,36,39H,16-17,19H2,1H3/b34-32-
UniProtKB/SwissProt

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n/an/a 354n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384074
PNG
(US10280166, Compound 2242)
Show SMILES CC(C)CC(=O)Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3cc(F)cc(OCCN4CCCC4)c3)c2c1
Show InChI InChI=1S/C35H33FN8O2/c1-21(2)13-31(45)39-26-15-24(19-37-20-26)22-5-6-30-29(17-22)33(43-42-30)35-40-32-28(7-8-38-34(32)41-35)23-14-25(36)18-27(16-23)46-12-11-44-9-3-4-10-44/h5-8,14-21H,3-4,9-13H2,1-2H3,(H,39,45)/b35-33-
UniProtKB/SwissProt

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n/an/a 440n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384045
PNG
(US10280166, Compound 466)
Show SMILES CN(C)CCNc1cc(F)cc(c1)-c1ccnc2[nH]c(nc12)-c1n[nH]c2ccc(cc12)-c1cncc(CNCC2CCCC2)c1
Show InChI InChI=1S/C35H36FN9/c1-45(2)12-11-39-28-15-25(14-27(36)17-28)29-9-10-40-34-32(29)41-35(42-34)33-30-16-24(7-8-31(30)43-44-33)26-13-23(20-38-21-26)19-37-18-22-5-3-4-6-22/h7-10,13-17,20-22,37,39H,3-6,11-12,18-19H2,1-2H3/b35-33-
UniProtKB/SwissProt

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n/an/a 442n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384053
PNG
(US10280166, Compound 1677)
Show SMILES CN(C)Cc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3ccsc3)c2c1F
Show InChI InChI=1S/C25H18FN7S/c1-33(2)12-14-9-16(11-27-10-14)17-3-4-19-20(21(17)26)23(32-31-19)25-29-22-18(15-6-8-34-13-15)5-7-28-24(22)30-25/h3-11,13H,12H2,1-2H3/b25-23-
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n/an/a 673n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384065
PNG
(US10280166, Compound 1883)
Show SMILES CN(C)CCOc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3cccc(F)c3)c2c1
Show InChI InChI=1S/C28H22FN7O/c1-36(2)10-11-37-21-13-19(15-30-16-21)17-6-7-24-23(14-17)26(35-34-24)28-32-25-22(8-9-31-27(25)33-28)18-4-3-5-20(29)12-18/h3-9,12-16H,10-11H2,1-2H3/b28-26-
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n/an/a 753n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384054
PNG
(US10280166, Compound 1833)
Show SMILES CN(C)Cc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3cc(F)cc(CNS(C)(=O)=O)c3)c2c1F
Show InChI InChI=1S/C29H24F2N8O2S/c1-39(2)15-17-9-19(14-32-12-17)21-4-5-23-24(25(21)31)27(38-37-23)29-35-26-22(6-7-33-28(26)36-29)18-8-16(10-20(30)11-18)13-34-42(3,40)41/h4-12,14,34H,13,15H2,1-3H3/b29-27-
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n/an/a 773n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383998
PNG
(US10280166, Compound 234)
Show SMILES CN1CCN(CC1)c1ccnc2[nH]c(nc12)-c1n[nH]c2ccc(cc12)-c1cncnc1
Show InChI InChI=1S/C22H19N9/c1-30-6-8-31(9-7-30)18-4-5-25-21-20(18)26-22(27-21)19-16-10-14(2-3-17(16)28-29-19)15-11-23-13-24-12-15/h2-5,10-13H,6-9H2,1H3/b22-19-
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n/an/a 795n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384051
PNG
(US10280166, Compound 1365)
Show SMILES CN(C)Cc1cncc(c1)-c1cc2c(n[nH]c2cc1F)-c1nc2c(ccnc2[nH]1)-c1cc(F)cc(CNS(C)(=O)=O)c1
Show InChI InChI=1S/C29H24F2N8O2S/c1-39(2)15-17-7-19(14-32-12-17)22-10-23-25(11-24(22)31)37-38-27(23)29-35-26-21(4-5-33-28(26)36-29)18-6-16(8-20(30)9-18)13-34-42(3,40)41/h4-12,14,34H,13,15H2,1-3H3/b29-27-
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n/an/a 804n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384052
PNG
(US10280166, Compound 1417)
Show SMILES CN(C)Cc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3cccc(F)c3)c2c1F
Show InChI InChI=1S/C27H19F2N7/c1-36(2)14-15-10-17(13-30-12-15)19-6-7-21-22(23(19)29)25(35-34-21)27-32-24-20(8-9-31-26(24)33-27)16-4-3-5-18(28)11-16/h3-13H,14H2,1-2H3/b27-25-
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n/an/a 923n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384024
PNG
(US10280166, Compound 325)
Show SMILES CN(C)Cc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3cccs3)c2c1
Show InChI InChI=1S/C25H19N7S/c1-32(2)14-15-10-17(13-26-12-15)16-5-6-20-19(11-16)23(31-30-20)25-28-22-18(21-4-3-9-33-21)7-8-27-24(22)29-25/h3-13H,14H2,1-2H3/b25-23-
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n/an/a 932n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384047
PNG
(US10280166, Compound 741)
Show SMILES CN(C)Cc1cncc(c1)-c1cc(F)c2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3ccsc3)c2c1
Show InChI InChI=1S/C25H18FN7S/c1-33(2)12-14-7-17(11-27-10-14)16-8-19-21(20(26)9-16)31-32-23(19)25-29-22-18(15-4-6-34-13-15)3-5-28-24(22)30-25/h3-11,13H,12H2,1-2H3/b25-23-
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n/an/a 936n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384071
PNG
(US10280166, Compound 1889)
Show SMILES Fc1cccc(c1)-c1ccnc2[nH]c(nc12)-c1n[nH]c2ccc(cc12)-c1ccccn1
Show InChI InChI=1S/C24H13FN6/c25-16-5-3-4-14(12-16)17-9-11-27-23-21(17)28-24(29-23)22-18-13-15(7-8-20(18)30-31-22)19-6-1-2-10-26-19/h1-13H/b24-22-
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n/an/a>1.00E+3n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384056
PNG
(US10280166, Compound 1874)
Show SMILES Fc1cccc(c1)-c1ccnc2[nH]c(nc12)-c1n[nH]c2ccc(cc12)C1=CCNCC1
Show InChI InChI=1S/C24H17FN6/c25-17-3-1-2-16(12-17)18-8-11-27-23-21(18)28-24(29-23)22-19-13-15(4-5-20(19)30-31-22)14-6-9-26-10-7-14/h1-6,8,11-13,26H,7,9-10H2/b24-22-
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n/an/a>1.00E+3n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384062
PNG
(US10280166, Compound 1880)
Show SMILES Fc1cccc(c1)-c1ccnc2[nH]c(nc12)-c1n[nH]c2ccc(cc12)-c1cncc(OC2CCNCC2)c1
Show InChI InChI=1S/C29H22FN7O/c30-20-3-1-2-18(12-20)23-8-11-33-28-26(23)34-29(35-28)27-24-14-17(4-5-25(24)36-37-27)19-13-22(16-32-15-19)38-21-6-9-31-10-7-21/h1-5,8,11-16,21,31H,6-7,9-10H2/b29-27-
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n/an/a 1.19E+3n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384019
PNG
(US10280166, Compound 310)
Show SMILES C(NCc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3ccoc3)c2c1)C1CCCC1
Show InChI InChI=1S/C29H25N7O/c1-2-4-18(3-1)13-30-14-19-11-22(16-31-15-19)20-5-6-25-24(12-20)27(36-35-25)29-33-26-23(21-8-10-37-17-21)7-9-32-28(26)34-29/h5-12,15-18,30H,1-4,13-14H2/b29-27-
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n/an/a 1.27E+3n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383988
PNG
(US10280166, Compound 169)
Show SMILES CN(C)Cc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)N3CCCCC3)c2c1
Show InChI InChI=1S/C26H26N8/c1-33(2)16-17-12-19(15-27-14-17)18-6-7-21-20(13-18)23(32-31-21)26-29-24-22(8-9-28-25(24)30-26)34-10-4-3-5-11-34/h6-9,12-15H,3-5,10-11,16H2,1-2H3/b26-23-
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n/an/a 1.45E+3n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383985
PNG
(US10280166, Compound 154)
Show SMILES C(NCc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3ccccn3)c2c1)C1CCCC1
Show InChI InChI=1S/C30H26N8/c1-2-6-19(5-1)15-31-16-20-13-22(18-32-17-20)21-8-9-26-24(14-21)28(38-37-26)30-35-27-23(10-12-34-29(27)36-30)25-7-3-4-11-33-25/h3-4,7-14,17-19,31H,1-2,5-6,15-16H2/b30-28-
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n/an/a 1.46E+3n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383981
PNG
(US10280166, Compound 136)
Show SMILES CCNCc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3ccccn3)c2c1
Show InChI InChI=1S/C26H20N8/c1-2-27-13-16-11-18(15-28-14-16)17-6-7-22-20(12-17)24(34-33-22)26-31-23-19(8-10-30-25(23)32-26)21-5-3-4-9-29-21/h3-12,14-15,27H,2,13H2,1H3/b26-24-
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n/an/a 1.55E+3n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383990
PNG
(US10280166, Compound 181)
Show SMILES FC1(F)CCN(Cc2cncc(c2)-c2ccc3[nH]nc(-c4nc5c(ccnc5[nH]4)N4CCCCC4)c3c2)C1
Show InChI InChI=1S/C28H26F2N8/c29-28(30)7-11-37(17-28)16-18-12-20(15-31-14-18)19-4-5-22-21(13-19)24(36-35-22)27-33-25-23(6-8-32-26(25)34-27)38-9-2-1-3-10-38/h4-6,8,12-15H,1-3,7,9-11,16-17H2/b27-24-
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n/an/a 2.58E+3n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383996
PNG
(US10280166, Compound 223)
Show SMILES CN1CCN(CC1)c1ccnc2[nH]c(nc12)-c1n[nH]c2ccc(cc12)-c1cncc(CN2CCCCC2)c1
Show InChI InChI=1S/C29H31N9/c1-36-11-13-38(14-12-36)25-7-8-31-28-27(25)32-29(33-28)26-23-16-21(5-6-24(23)34-35-26)22-15-20(17-30-18-22)19-37-9-3-2-4-10-37/h5-8,15-18H,2-4,9-14,19H2,1H3/b29-26-
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n/an/a 3.07E+3n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384055
PNG
(US10280166, Compound 1873)
Show SMILES Fc1cccc(c1)-c1ccnc2[nH]c(nc12)-c1n[nH]c2ccc(cc12)C1CCNCC1
Show InChI InChI=1S/C24H19FN6/c25-17-3-1-2-16(12-17)18-8-11-27-23-21(18)28-24(29-23)22-19-13-15(4-5-20(19)30-31-22)14-6-9-26-10-7-14/h1-5,8,11-14,26H,6-7,9-10H2/b24-22-
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n/an/a 3.27E+3n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383962
PNG
(US10280166, Compound 40)
Show SMILES Fc1ccc(cc1)-c1ccnc2[nH]c(nc12)-c1n[nH]c2ccc(cc12)-c1cncc(CN2CCCC2)c1
Show InChI InChI=1S/C29H22FN7/c30-22-6-3-19(4-7-22)23-9-10-32-28-26(23)33-29(34-28)27-24-14-20(5-8-25(24)35-36-27)21-13-18(15-31-16-21)17-37-11-1-2-12-37/h3-10,13-16H,1-2,11-12,17H2/b29-27-
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n/an/a 4.03E+3n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384000
PNG
(US10280166, Compound 239)
Show SMILES Cc1ccncc1-c1ccc2[nH]nc(-c3nc4cccnc4[nH]3)c2c1
Show InChI InChI=1S/C19H12N6/c1-11-6-8-20-10-14(11)12-4-5-15-13(9-12)17(25-24-15)19-22-16-3-2-7-21-18(16)23-19/h2-10H,1H3/b19-17-
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n/an/a 4.10E+3n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384064
PNG
(US10280166, Compound 1882)
Show SMILES Fc1cccc(c1)-c1ccnc2[nH]c(nc12)-c1n[nH]c2ccc(cc12)-c1cncc(OCCN2CCCC2)c1
Show InChI InChI=1S/C30H24FN7O/c31-22-5-3-4-20(14-22)24-8-9-33-29-27(24)34-30(35-29)28-25-16-19(6-7-26(25)36-37-28)21-15-23(18-32-17-21)39-13-12-38-10-1-2-11-38/h3-9,14-18H,1-2,10-13H2/b30-28-
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n/an/a 4.14E+3n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383975
PNG
(US10280166, Compound 93)
Show SMILES C(N1CCCCC1)c1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3cccnc3)c2c1
Show InChI InChI=1S/C29H24N8/c1-2-11-37(12-3-1)18-19-13-22(17-31-15-19)20-6-7-25-24(14-20)27(36-35-25)29-33-26-23(8-10-32-28(26)34-29)21-5-4-9-30-16-21/h4-10,13-17H,1-3,11-12,18H2/b29-27-
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n/an/a>1.00E+4n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384061
PNG
(US10280166, Compound 1879 | US10280166, Compound 1...)
Show SMILES COc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3cccc(F)c3)c2c1
Show InChI InChI=1S/C25H15FN6O/c1-33-18-10-16(12-27-13-18)14-5-6-21-20(11-14)23(32-31-21)25-29-22-19(7-8-28-24(22)30-25)15-3-2-4-17(26)9-15/h2-13H,1H3/b25-23-
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n/an/a>1.00E+4n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM383976
PNG
(US10280166, Compound 101)
Show SMILES C(NCc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3cccnc3)c2c1)c1ccccc1
Show InChI InChI=1S/C31H22N8/c1-2-5-20(6-3-1)15-33-16-21-13-24(19-34-17-21)22-8-9-27-26(14-22)29(39-38-27)31-36-28-25(10-12-35-30(28)37-31)23-7-4-11-32-18-23/h1-14,17-19,33H,15-16H2/b31-29-
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n/an/a>1.00E+4n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384061
PNG
(US10280166, Compound 1879 | US10280166, Compound 1...)
Show SMILES COc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3cccc(F)c3)c2c1
Show InChI InChI=1S/C25H15FN6O/c1-33-18-10-16(12-27-13-18)14-5-6-21-20(11-14)23(32-31-21)25-29-22-19(7-8-28-24(22)30-25)15-3-2-4-17(26)9-15/h2-13H,1H3/b25-23-
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n/an/a>1.00E+4n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384070
PNG
(US10280166, Compound 1888)
Show SMILES Fc1cccc(c1)-c1ccnc2[nH]c(nc12)-c1n[nH]c2ccc(cc12)-c1ccncc1
Show InChI InChI=1S/C24H13FN6/c25-17-3-1-2-16(12-17)18-8-11-27-23-21(18)28-24(29-23)22-19-13-15(4-5-20(19)30-31-22)14-6-9-26-10-7-14/h1-13H/b24-22-
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n/an/a>1.00E+4n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384069
PNG
(US10280166, Compound 1887)
Show SMILES Fc1cccc(c1)-c1ccnc2[nH]c(nc12)-c1n[nH]c2ccc(cc12)-c1cncc(NC(=O)CC2CCCCC2)c1
Show InChI InChI=1S/C32H26FN7O/c33-23-8-4-7-21(14-23)25-11-12-35-31-29(25)37-32(38-31)30-26-16-20(9-10-27(26)39-40-30)22-15-24(18-34-17-22)36-28(41)13-19-5-2-1-3-6-19/h4,7-12,14-19H,1-3,5-6,13H2,(H,36,41)/b32-30-
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n/an/a>1.00E+4n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384050
PNG
(US10280166, Compound 1209)
Show SMILES CN(C)Cc1cncc(c1)-c1cc2c(n[nH]c2cc1F)-c1nc2c(ccnc2[nH]1)-c1ccsc1
Show InChI InChI=1S/C25H18FN7S/c1-33(2)12-14-7-16(11-27-10-14)18-8-19-21(9-20(18)26)31-32-23(19)25-29-22-17(15-4-6-34-13-15)3-5-28-24(22)30-25/h3-11,13H,12H2,1-2H3/b25-23-
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n/an/a>1.00E+4n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384049
PNG
(US10280166, Compound 949)
Show SMILES CN(C)Cc1cncc(c1)-c1cc2c(n[nH]c2cc1F)-c1nc2c(ccnc2[nH]1)-c1cccc(F)c1
Show InChI InChI=1S/C27H19F2N7/c1-36(2)14-15-8-17(13-30-12-15)20-10-21-23(11-22(20)29)34-35-25(21)27-32-24-19(6-7-31-26(24)33-27)16-4-3-5-18(28)9-16/h3-13H,14H2,1-2H3/b27-25-
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n/an/a>1.00E+4n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384059
PNG
(US10280166, Compound 1877)
Show SMILES Cc1ncc(-c2ccc3[nH]nc(-c4nc5c(ccnc5[nH]4)-c4cccc(F)c4)c3c2)n1C
Show InChI InChI=1S/C24H16FN7/c1-13-27-12-20(32(13)2)15-6-7-19-18(11-15)22(31-30-19)24-28-21-17(8-9-26-23(21)29-24)14-4-3-5-16(25)10-14/h3-12H,1-2H3/b24-22-
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n/an/a>1.00E+4n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384068
PNG
(US10280166, Compound 1886)
Show SMILES Fc1cccc(c1)-c1ccnc2[nH]c(nc12)-c1n[nH]c2ccc(cc12)-c1cncc(OCc2ccccc2)c1
Show InChI InChI=1S/C31H19FN6O/c32-23-8-4-7-21(13-23)25-11-12-34-30-28(25)35-31(36-30)29-26-15-20(9-10-27(26)37-38-29)22-14-24(17-33-16-22)39-18-19-5-2-1-3-6-19/h1-17H,18H2/b31-29-
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n/an/a>1.00E+4n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10280166 (2019)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%