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Patent code US10285982

Compile Data Set for Download or QSAR
Found 66 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384555
PNG
(US10285982, Compound 20)
Show SMILES Fc1cccc(c1)-c1ccnc2[nH]c(cc12)-c1n[nH]c2cnc(cc12)-c1cncc(NC(=O)C2CC2)c1
Show InChI InChI=1S/C28H18FN7O/c29-18-3-1-2-16(8-18)20-6-7-31-27-21(20)10-24(34-27)26-22-11-23(32-14-25(22)35-36-26)17-9-19(13-30-12-17)33-28(37)15-4-5-15/h1-3,6-15H,4-5H2,(H,33,37)/b26-24-
UniProtKB/SwissProt

GoogleScholar
UniChem
US Patent
n/an/an/an/a 97n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384562
PNG
(US10285982, Compound 27)
Show SMILES Fc1cccc(c1)-c1ccnc2[nH]c(cc12)-c1n[nH]c2cnc(cc12)-c1cncnc1
Show InChI InChI=1S/C23H12FN7/c24-15-3-1-2-13(6-15)16-4-5-27-23-17(16)7-20(29-23)22-18-8-19(14-9-25-12-26-10-14)28-11-21(18)30-31-22/h1-12H/b22-20-
UniProtKB/SwissProt

GoogleScholar
UniChem
US Patent
n/an/an/an/a 507n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384567
PNG
(US10285982, Compound 30)
Show SMILES CC(C)CC(=O)Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)-c1ccc(F)cc1
Show InChI InChI=1S/C29H22FN7O/c1-16(2)9-27(38)34-20-10-18(13-31-14-20)24-12-23-26(15-33-24)36-37-28(23)25-11-22-21(7-8-32-29(22)35-25)17-3-5-19(30)6-4-17/h3-8,10-16H,9H2,1-2H3,(H,34,38)/b28-25-
UniProtKB/SwissProt

GoogleScholar
UniChem
US Patent
n/an/an/an/a 444n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384665
PNG
(US10285982, Compound 54)
Show SMILES Fc1ccc(cc1)-c1ccnc2[nH]c(cc12)-c1n[nH]c2cnc(cc12)-c1cncc(CN2CCC(F)(F)C2)c1
Show InChI InChI=1S/C29H20F3N7/c30-20-3-1-18(2-4-20)21-5-7-34-28-22(21)10-25(36-28)27-23-11-24(35-14-26(23)37-38-27)19-9-17(12-33-13-19)15-39-8-6-29(31,32)16-39/h1-5,7,9-14H,6,8,15-16H2/b27-25-
UniProtKB/SwissProt

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UniChem
US Patent
n/an/an/an/a>1.00E+4n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384668
PNG
(US10285982, Compound 66)
Show SMILES Fc1ccccc1-c1ccnc2[nH]c(cc12)-c1n[nH]c2cnc(cc12)-c1cncc(NC(=O)Cc2ccccc2)c1
Show InChI InChI=1S/C32H20FN7O/c33-26-9-5-4-8-23(26)22-10-11-35-32-24(22)14-28(38-32)31-25-15-27(36-18-29(25)39-40-31)20-13-21(17-34-16-20)37-30(41)12-19-6-2-1-3-7-19/h1-11,13-18H,12H2,(H,37,41)/b31-28-
UniProtKB/SwissProt

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US Patent
n/an/an/an/a 139n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384670
PNG
(US10285982, Compound 75)
Show SMILES CCCCC(=O)Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)-c1ccccc1F
Show InChI InChI=1S/C29H22FN7O/c1-2-3-8-27(38)34-18-11-17(14-31-15-18)24-13-22-26(16-33-24)36-37-28(22)25-12-21-19(9-10-32-29(21)35-25)20-6-4-5-7-23(20)30/h4-7,9-16H,2-3,8H2,1H3,(H,34,38)/b28-25-
UniProtKB/SwissProt

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US Patent
n/an/an/an/a 542n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384678
PNG
(US10285982, Compound 103)
Show SMILES CCCCC(=O)Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)-c1cccnc1
Show InChI InChI=1S/C28H22N8O/c1-2-3-6-26(37)33-19-10-18(14-30-15-19)23-12-22-25(16-32-23)35-36-27(22)24-11-21-20(7-9-31-28(21)34-24)17-5-4-8-29-13-17/h4-5,7-16H,2-3,6H2,1H3,(H,33,37)/b27-24-
UniProtKB/SwissProt

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US Patent
n/an/an/an/a>1.00E+4n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384680
PNG
(US10285982, Compound 114)
Show SMILES CC(C)CC(=O)Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)-c1ccncc1
Show InChI InChI=1S/C28H22N8O/c1-16(2)9-26(37)33-19-10-18(13-30-14-19)23-12-22-25(15-32-23)35-36-27(22)24-11-21-20(5-8-31-28(21)34-24)17-3-6-29-7-4-17/h3-8,10-16H,9H2,1-2H3,(H,33,37)/b27-24-
UniProtKB/SwissProt

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UniChem
US Patent
n/an/an/an/a>1.00E+4n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384686
PNG
(US10285982, Compound 140)
Show SMILES c1c([nH]c2nccc(-c3ccncc3)c12)-c1n[nH]c2cnc(cc12)-c1ccccn1
Show InChI InChI=1S/C23H13N7/c1-2-7-25-18(3-1)19-12-17-21(13-27-19)29-30-22(17)20-11-16-15(6-10-26-23(16)28-20)14-4-8-24-9-5-14/h1-13H/b22-20-
UniProtKB/SwissProt

GoogleScholar
UniChem
US Patent
n/an/an/an/a>1.00E+4n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384689
PNG
(US10285982, Compound 180)
Show SMILES CC(C)Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)N1CCCCC1
Show InChI InChI=1S/C26H26N8/c1-16(2)30-18-10-17(13-27-14-18)21-11-19-23(15-29-21)32-33-25(19)22-12-20-24(6-7-28-26(20)31-22)34-8-4-3-5-9-34/h6-7,10-16,30H,3-5,8-9H2,1-2H3/b25-22-
UniProtKB/SwissProt

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UniChem
US Patent
n/an/an/an/a 1.63E+3n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384691
PNG
(US10285982, Compound 184)
Show SMILES CC(C)(C)CC(=O)Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)N1CCCCC1
Show InChI InChI=1S/C29H30N8O/c1-29(2,3)14-26(38)33-19-11-18(15-30-16-19)22-12-20-24(17-32-22)35-36-27(20)23-13-21-25(7-8-31-28(21)34-23)37-9-5-4-6-10-37/h7-8,11-13,15-17H,4-6,9-10,14H2,1-3H3,(H,33,38)/b27-23-
UniProtKB/SwissProt

GoogleScholar
UniChem
US Patent
n/an/an/an/a 3.24E+3n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384700
PNG
(US10285982, Compound 275)
Show SMILES O=C(Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2cccnc2[nH]1)C1CCCCC1
Show InChI InChI=1S/C25H21N7O/c33-25(15-5-2-1-3-6-15)29-18-9-17(12-26-13-18)20-11-19-22(14-28-20)31-32-23(19)21-10-16-7-4-8-27-24(16)30-21/h4,7-15H,1-3,5-6H2,(H,29,33)/b23-21-
UniProtKB/SwissProt

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US Patent
n/an/an/an/a>1.00E+4n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384704
PNG
(US10285982, Compound 351)
Show SMILES C(N1CCCCC1)c1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)-c1cccs1
Show InChI InChI=1S/C28H23N7S/c1-2-8-35(9-3-1)17-18-11-19(15-29-14-18)23-13-22-25(16-31-23)33-34-27(22)24-12-21-20(26-5-4-10-36-26)6-7-30-28(21)32-24/h4-7,10-16H,1-3,8-9,17H2/b27-24-
UniProtKB/SwissProt

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UniChem
US Patent
n/an/an/an/a 6.90E+3n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384712
PNG
(US10285982, Compound 601)
Show SMILES C1CCN(CC1)c1ccnc2[nH]c(cc12)-c1n[nH]c2cnc(cc12)C1CCNCC1
Show InChI InChI=1S/C23H25N7/c1-2-10-30(11-3-1)21-6-9-25-23-17(21)13-19(27-23)22-16-12-18(15-4-7-24-8-5-15)26-14-20(16)28-29-22/h6,9,12-15,24H,1-5,7-8,10-11H2/b22-19-
UniProtKB/SwissProt

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UniChem
US Patent
n/an/an/an/a>1.00E+4n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384714
PNG
(US10285982, Compound 641)
Show SMILES CN1CCN(CC1)c1ccnc2[nH]c(cc12)-c1n[nH]c2cnc(cc12)-c1cncc(NC(=O)CC2CCNCC2)c1
Show InChI InChI=1S/C30H32N10O/c1-39-8-10-40(11-9-39)27-4-7-33-30-23(27)15-25(36-30)29-22-14-24(34-18-26(22)37-38-29)20-13-21(17-32-16-20)35-28(41)12-19-2-5-31-6-3-19/h4,7,13-19,31H,2-3,5-6,8-12H2,1H3,(H,35,41)/b29-25-
UniProtKB/SwissProt

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UniChem
US Patent
n/an/an/an/a>1.00E+4n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384614
PNG
(US10285982, Compound 44)
Show SMILES CC(C)(C)CC(=O)Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)-c1ccc(F)cc1
Show InChI InChI=1S/C30H24FN7O/c1-30(2,3)13-27(39)35-20-10-18(14-32-15-20)24-12-23-26(16-34-24)37-38-28(23)25-11-22-21(8-9-33-29(22)36-25)17-4-6-19(31)7-5-17/h4-12,14-16H,13H2,1-3H3,(H,35,39)/b28-25-
UniProtKB/SwissProt

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UniChem
US Patent
n/an/an/an/a 144n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384697
PNG
(US10285982, Compound 262)
Show SMILES O=C(Cc1ccccc1)Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2cccnc2[nH]1
Show InChI InChI=1S/C26H17N7O/c34-24(9-16-5-2-1-3-6-16)30-19-10-18(13-27-14-19)21-12-20-23(15-29-21)32-33-25(20)22-11-17-7-4-8-28-26(17)31-22/h1-8,10-15H,9H2,(H,30,34)/b25-22-
UniProtKB/SwissProt

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UniChem
US Patent
n/an/an/an/a>1.00E+4n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384703
PNG
(US10285982, Compound 328)
Show SMILES O=C(Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)-c1ccoc1)C1CC1
Show InChI InChI=1S/C26H17N7O2/c34-26(14-1-2-14)30-17-7-16(10-27-11-17)21-9-20-23(12-29-21)32-33-24(20)22-8-19-18(15-4-6-35-13-15)3-5-28-25(19)31-22/h3-14H,1-2H2,(H,30,34)/b24-22-
UniProtKB/SwissProt

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US Patent
n/an/an/an/a 121n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384705
PNG
(US10285982, Compound 364)
Show SMILES c1csc(c1)-c1ccnc2[nH]c(cc12)-c1n[nH]c2cnc(cc12)-c1ccccn1
Show InChI InChI=1S/C22H12N6S/c1-2-7-23-16(4-1)17-11-15-19(12-25-17)27-28-21(15)18-10-14-13(20-5-3-9-29-20)6-8-24-22(14)26-18/h1-12H/b21-18-
UniProtKB/SwissProt

GoogleScholar
UniChem
US Patent
n/an/an/an/a 630n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384707
PNG
(US10285982, Compound 466)
Show SMILES CN(C)CCNc1cc(F)cc(c1)-c1ccnc2[nH]c(cc12)-c1n[nH]c2cnc(cc12)-c1ccncc1
Show InChI InChI=1S/C28H23FN8/c1-37(2)10-9-31-20-12-18(11-19(29)13-20)21-5-8-32-28-22(21)14-25(34-28)27-23-15-24(17-3-6-30-7-4-17)33-16-26(23)35-36-27/h3-8,11-16,31H,9-10H2,1-2H3/b27-25-
UniProtKB/SwissProt

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UniChem
US Patent
n/an/an/an/a>1.00E+4n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384552
PNG
(US10285982, Compound 8)
Show SMILES CC(C)(C)C(=O)Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)-c1cccc(F)c1
Show InChI InChI=1S/C29H22FN7O/c1-29(2,3)28(38)34-19-10-17(13-31-14-19)23-12-22-25(15-33-23)36-37-26(22)24-11-21-20(7-8-32-27(21)35-24)16-5-4-6-18(30)9-16/h4-15H,1-3H3,(H,34,38)/b26-24-
UniProtKB/SwissProt

GoogleScholar
UniChem
US Patent
n/an/an/an/a 73n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384624
PNG
(US10285982, Compound 49)
Show SMILES Fc1ccc(cc1)-c1ccnc2[nH]c(cc12)-c1n[nH]c2cnc(cc12)-c1cncc(NC(=O)C2CCC2)c1
Show InChI InChI=1S/C29H20FN7O/c30-19-6-4-16(5-7-19)21-8-9-32-28-22(21)11-25(35-28)27-23-12-24(33-15-26(23)36-37-27)18-10-20(14-31-13-18)34-29(38)17-2-1-3-17/h4-15,17H,1-3H2,(H,34,38)/b27-25-
UniProtKB/SwissProt

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UniChem
US Patent
n/an/an/an/a 747n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384677
PNG
(US10285982, Compound 98)
Show SMILES C(N1CCCC1)c1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)-c1cccnc1
Show InChI InChI=1S/C28H22N8/c1-2-9-36(8-1)17-18-10-20(15-30-13-18)24-12-23-26(16-32-24)34-35-27(23)25-11-22-21(5-7-31-28(22)33-25)19-4-3-6-29-14-19/h3-7,10-16H,1-2,8-9,17H2/b27-25-
UniProtKB/SwissProt

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US Patent
n/an/an/an/a>1.00E+4n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384679
PNG
(US10285982, Compound 111)
Show SMILES c1c([nH]c2nccc(-c3cccnc3)c12)-c1n[nH]c2cnc(cc12)-c1cncnc1
Show InChI InChI=1S/C22H12N8/c1-2-13(8-23-4-1)15-3-5-26-22-16(15)6-19(28-22)21-17-7-18(14-9-24-12-25-10-14)27-11-20(17)29-30-21/h1-12H/b21-19-
UniProtKB/SwissProt

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US Patent
n/an/an/an/a>1.00E+4n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384694
PNG
(US10285982, Compound 249)
Show SMILES CN1CCN(CC1)c1ccnc2[nH]c(cc12)-c1n[nH]c2cnc(cc12)-c1cncc(CNCC2CCCC2)c1
Show InChI InChI=1S/C30H33N9/c1-38-8-10-39(11-9-38)28-6-7-33-30-24(28)14-26(35-30)29-23-13-25(34-19-27(23)36-37-29)22-12-21(17-32-18-22)16-31-15-20-4-2-3-5-20/h6-7,12-14,17-20,31H,2-5,8-11,15-16H2,1H3/b29-26-
UniProtKB/SwissProt

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US Patent
n/an/an/an/a>1.00E+4n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384698
PNG
(US10285982, Compound 263)
Show SMILES O=C(Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2cccnc2[nH]1)c1ccccc1
Show InChI InChI=1S/C25H15N7O/c33-25(15-5-2-1-3-6-15)29-18-9-17(12-26-13-18)20-11-19-22(14-28-20)31-32-23(19)21-10-16-7-4-8-27-24(16)30-21/h1-14H,(H,29,33)/b23-21-
UniProtKB/SwissProt

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US Patent
n/an/an/an/a>1.00E+4n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384701
PNG
(US10285982, Compound 278)
Show SMILES FC1(F)CCN(Cc2cncc(c2)-c2cc3c(n[nH]c3cn2)-c2cc3cccnc3[nH]2)C1
Show InChI InChI=1S/C23H17F2N7/c24-23(25)3-5-32(13-23)12-14-6-16(10-26-9-14)18-8-17-20(11-28-18)30-31-21(17)19-7-15-2-1-4-27-22(15)29-19/h1-2,4,6-11H,3,5,12-13H2/b21-19-
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US Patent
n/an/an/an/a 1.35E+3n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384709
PNG
(US10285982, Compound 518)
Show SMILES Fc1cccc(c1)-c1ccnc2[nH]c(cc12)-c1n[nH]c2cnc(cc12)-c1cncc(OCc2ccccc2)c1
Show InChI InChI=1S/C31H19FN6O/c32-22-8-4-7-20(11-22)24-9-10-34-31-25(24)13-28(36-31)30-26-14-27(35-17-29(26)37-38-30)21-12-23(16-33-15-21)39-18-19-5-2-1-3-6-19/h1-17H,18H2/b30-28-
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US Patent
n/an/an/an/a>1.00E+4n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384553
PNG
(US10285982, Compound 11)
Show SMILES Fc1cccc(c1)-c1ccnc2[nH]c(cc12)-c1n[nH]c2cnc(cc12)-c1cncc(NC(=O)c2ccccc2)c1
Show InChI InChI=1S/C31H18FN7O/c32-21-8-4-7-19(11-21)23-9-10-34-30-24(23)13-27(37-30)29-25-14-26(35-17-28(25)38-39-29)20-12-22(16-33-15-20)36-31(40)18-5-2-1-3-6-18/h1-17H,(H,36,40)/b29-27-
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US Patent
n/an/an/an/a>1.00E+4n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384586
PNG
(US10285982, Compound 37)
Show SMILES CC(C)C(=O)Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)-c1ccc(F)cc1
Show InChI InChI=1S/C28H20FN7O/c1-15(2)28(37)33-19-9-17(12-30-13-19)23-11-22-25(14-32-23)35-36-26(22)24-10-21-20(7-8-31-27(21)34-24)16-3-5-18(29)6-4-16/h3-15H,1-2H3,(H,33,37)/b26-24-
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US Patent
n/an/an/an/a 671n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384675
PNG
(US10285982, Compound 95)
Show SMILES O=C(Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)-c1cccnc1)c1ccccc1
Show InChI InChI=1S/C30H18N8O/c39-30(18-5-2-1-3-6-18)35-21-11-20(15-32-16-21)25-13-24-27(17-34-25)37-38-28(24)26-12-23-22(8-10-33-29(23)36-26)19-7-4-9-31-14-19/h1-17H,(H,35,39)/b28-26-
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n/an/an/an/a>1.00E+4n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384688
PNG
(US10285982, Compound 177)
Show SMILES CC(C)C(=O)Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)N1CCCCC1
Show InChI InChI=1S/C27H26N8O/c1-16(2)27(36)31-18-10-17(13-28-14-18)21-11-19-23(15-30-21)33-34-25(19)22-12-20-24(6-7-29-26(20)32-22)35-8-4-3-5-9-35/h6-7,10-16H,3-5,8-9H2,1-2H3,(H,31,36)/b25-22-
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n/an/an/an/a 867n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384702
PNG
(US10285982, Compound 311)
Show SMILES Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)-c1ccoc1
Show InChI InChI=1S/C22H13N7O/c23-14-5-13(8-24-9-14)18-7-17-20(10-26-18)28-29-21(17)19-6-16-15(12-2-4-30-11-12)1-3-25-22(16)27-19/h1-11H,23H2/b21-19-
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US Patent
n/an/an/an/a>1.00E+4n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384706
PNG
(US10285982, Compound 465)
Show SMILES CCCC(=O)Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)-c1cc(F)cc(NCCN(C)C)c1
Show InChI InChI=1S/C32H30FN9O/c1-4-5-30(43)38-23-12-20(16-34-17-23)27-15-26-29(18-37-27)40-41-31(26)28-14-25-24(6-7-36-32(25)39-28)19-10-21(33)13-22(11-19)35-8-9-42(2)3/h6-7,10-18,35H,4-5,8-9H2,1-3H3,(H,38,43)/b31-28-
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US Patent
n/an/an/an/a>1.00E+4n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384708
PNG
(US10285982, Compound 475)
Show SMILES CN(C)CCNc1cc(F)cc(c1)-c1ccnc2[nH]c(cc12)-c1n[nH]c2cnc(cc12)-c1cncnc1
Show InChI InChI=1S/C27H22FN9/c1-37(2)6-5-31-19-8-16(7-18(28)9-19)20-3-4-32-27-21(20)10-24(34-27)26-22-11-23(17-12-29-15-30-13-17)33-14-25(22)35-36-26/h3-4,7-15,31H,5-6H2,1-2H3/b26-24-
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n/an/an/an/a>1.00E+4n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384551
PNG
(US10285982, Compound 4)
Show SMILES Fc1cccc(c1)-c1ccnc2[nH]c(cc12)-c1n[nH]c2cnc(cc12)-c1cccnc1
Show InChI InChI=1S/C24H13FN6/c25-16-5-1-3-14(9-16)17-6-8-27-24-18(17)10-21(29-24)23-19-11-20(15-4-2-7-26-12-15)28-13-22(19)30-31-23/h1-13H/b23-21-
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US Patent
n/an/an/an/a 1.21E+3n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384554
PNG
(US10285982, Compound 14)
Show SMILES Fc1cccc(c1)-c1ccnc2[nH]c(cc12)-c1n[nH]c2cnc(cc12)-c1cncc(CN2CCCC2)c1
Show InChI InChI=1S/C29H22FN7/c30-21-5-3-4-19(11-21)22-6-7-32-29-23(22)12-26(34-29)28-24-13-25(33-16-27(24)35-36-28)20-10-18(14-31-15-20)17-37-8-1-2-9-37/h3-7,10-16H,1-2,8-9,17H2/b28-26-
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US Patent
n/an/an/an/a>1.00E+4n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384585
PNG
(US10285982, Compound 33)
Show SMILES Cc1ccncc1-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)-c1ccc(F)cc1
Show InChI InChI=1S/C25H15FN6/c1-14-6-8-27-12-20(14)21-11-19-23(13-29-21)31-32-24(19)22-10-18-17(7-9-28-25(18)30-22)15-2-4-16(26)5-3-15/h2-13H,1H3/b24-22-
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n/an/an/an/a 642n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384596
PNG
(US10285982, Compound 40)
Show SMILES CC(C)Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)-c1ccc(F)cc1
Show InChI InChI=1S/C27H20FN7/c1-15(2)32-19-9-17(12-29-13-19)23-11-22-25(14-31-23)34-35-26(22)24-10-21-20(7-8-30-27(21)33-24)16-3-5-18(28)6-4-16/h3-15,32H,1-2H3/b26-24-
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US Patent
n/an/an/an/a 223n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384669
PNG
(US10285982, Compound 69)
Show SMILES CN(C)Cc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)-c1ccccc1F
Show InChI InChI=1S/C27H20FN7/c1-35(2)15-16-9-17(13-29-12-16)23-11-21-25(14-31-23)33-34-26(21)24-10-20-18(7-8-30-27(20)32-24)19-5-3-4-6-22(19)28/h3-14H,15H2,1-2H3/b26-24-
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US Patent
n/an/an/an/a>1.00E+4n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384673
PNG
(US10285982, Compound 90)
Show SMILES CCNCc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)-c1cccnc1
Show InChI InChI=1S/C26H20N8/c1-2-27-11-16-8-18(14-29-12-16)22-10-21-24(15-31-22)33-34-25(21)23-9-20-19(5-7-30-26(20)32-23)17-4-3-6-28-13-17/h3-10,12-15,27H,2,11H2,1H3/b25-23-
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n/an/an/an/a 3.20E+3n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384674
PNG
(US10285982, Compound 92)
Show SMILES CC(C)(C)C(=O)Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)-c1cccnc1
Show InChI InChI=1S/C28H22N8O/c1-28(2,3)27(37)33-18-9-17(13-30-14-18)22-11-21-24(15-32-22)35-36-25(21)23-10-20-19(6-8-31-26(20)34-23)16-5-4-7-29-12-16/h4-15H,1-3H3,(H,33,37)/b25-23-
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n/an/an/an/a>1.00E+4n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384695
PNG
(US10285982, Compound 254)
Show SMILES CC(C)CC(=O)Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2cccnc2[nH]1
Show InChI InChI=1S/C23H19N7O/c1-13(2)6-21(31)27-16-7-15(10-24-11-16)18-9-17-20(12-26-18)29-30-22(17)19-8-14-4-3-5-25-23(14)28-19/h3-5,7-13H,6H2,1-2H3,(H,27,31)/b22-19-
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n/an/an/an/a>1.00E+4n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384713
PNG
(US10285982, Compound 635)
Show SMILES CN1CCN(CC1)c1ccnc2[nH]c(cc12)-c1n[nH]c2cnc(cc12)-c1cn[nH]c1
Show InChI InChI=1S/C21H21N9/c1-29-4-6-30(7-5-29)19-2-3-22-21-15(19)9-17(26-21)20-14-8-16(13-10-24-25-11-13)23-12-18(14)27-28-20/h2-3,8-12H,4-7H2,1H3,(H,22,26)(H,24,25)(H,27,28)
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n/an/an/an/a>1.00E+4n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384672
PNG
(US10285982, Compound 84)
Show SMILES Fc1ccccc1-c1ccnc2[nH]c(cc12)-c1n[nH]c2cnc(cc12)-c1ccccn1
Show InChI InChI=1S/C24H13FN6/c25-18-6-2-1-5-15(18)14-8-10-27-24-16(14)11-21(29-24)23-17-12-20(19-7-3-4-9-26-19)28-13-22(17)30-31-23/h1-13H/b23-21-
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n/an/an/an/a 279n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384681
PNG
(US10285982, Compound 117)
Show SMILES Cc1ccncc1-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)-c1ccncc1
Show InChI InChI=1S/C24H15N7/c1-14-2-6-26-12-19(14)20-11-18-22(13-28-20)30-31-23(18)21-10-17-16(5-9-27-24(17)29-21)15-3-7-25-8-4-15/h2-13H,1H3/b23-21-
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n/an/an/an/a>1.00E+4n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384692
PNG
(US10285982, Compound 188)
Show SMILES O=C(Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)N1CCCCC1)C1CC1
Show InChI InChI=1S/C27H24N8O/c36-27(16-4-5-16)31-18-10-17(13-28-14-18)21-11-19-23(15-30-21)33-34-25(19)22-12-20-24(6-7-29-26(20)32-22)35-8-2-1-3-9-35/h6-7,10-16H,1-5,8-9H2,(H,31,36)/b25-22-
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n/an/an/an/a 1.23E+3n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384693
PNG
(US10285982, Compound 231)
Show SMILES CN(C)c1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)N1CCN(C)CC1
Show InChI InChI=1S/C25H25N9/c1-32(2)17-10-16(13-26-14-17)20-11-18-22(15-28-20)30-31-24(18)21-12-19-23(4-5-27-25(19)29-21)34-8-6-33(3)7-9-34/h4-5,10-15H,6-9H2,1-3H3/b24-21-
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n/an/an/an/a>1.00E+4n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384710
PNG
(US10285982, Compound 533)
Show SMILES Oc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)-c1ccc(F)cc1
Show InChI InChI=1S/C24H13FN6O/c25-15-3-1-13(2-4-15)17-5-6-27-24-18(17)8-21(29-24)23-19-9-20(28-12-22(19)30-31-23)14-7-16(32)11-26-10-14/h1-12,32H/b23-21-
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n/an/an/an/a 456n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384711
PNG
(US10285982, Compound 563)
Show SMILES CN(C)CCOc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)-c1cccnc1
Show InChI InChI=1S/C27H22N8O/c1-35(2)8-9-36-19-10-18(14-29-15-19)23-12-22-25(16-31-23)33-34-26(22)24-11-21-20(5-7-30-27(21)32-24)17-4-3-6-28-13-17/h3-7,10-16H,8-9H2,1-2H3/b26-24-
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n/an/an/an/a>1.00E+4n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384666
PNG
(US10285982, Compound 59)
Show SMILES Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)-c1ccccc1F
Show InChI InChI=1S/C24H14FN7/c25-19-4-2-1-3-16(19)15-5-6-28-24-17(15)8-21(30-24)23-18-9-20(29-12-22(18)31-32-23)13-7-14(26)11-27-10-13/h1-12H,26H2/b23-21-
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n/an/an/an/a>1.00E+4n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384671
PNG
(US10285982, Compound 79)
Show SMILES Fc1ccccc1-c1ccnc2[nH]c(cc12)-c1n[nH]c2cnc(cc12)-c1cncc(NC(=O)C2CCCCC2)c1
Show InChI InChI=1S/C31H24FN7O/c32-25-9-5-4-8-22(25)21-10-11-34-30-23(21)13-27(37-30)29-24-14-26(35-17-28(24)38-39-29)19-12-20(16-33-15-19)36-31(40)18-6-2-1-3-7-18/h4-5,8-18H,1-3,6-7H2,(H,36,40)/b29-27-
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n/an/an/an/a 359n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384676
PNG
(US10285982, Compound 96)
Show SMILES CC(C)Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)-c1cccnc1
Show InChI InChI=1S/C26H20N8/c1-15(2)31-18-8-17(12-28-13-18)22-10-21-24(14-30-22)33-34-25(21)23-9-20-19(5-7-29-26(20)32-23)16-4-3-6-27-11-16/h3-15,31H,1-2H3/b25-23-
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n/an/an/an/a>1.00E+4n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384682
PNG
(US10285982, Compound 122)
Show SMILES O=C(Cc1ccccc1)Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)-c1ccncc1
Show InChI InChI=1S/C31H20N8O/c40-29(12-19-4-2-1-3-5-19)36-22-13-21(16-33-17-22)26-15-25-28(18-35-26)38-39-30(25)27-14-24-23(8-11-34-31(24)37-27)20-6-9-32-10-7-20/h1-11,13-18H,12H2,(H,36,40)/b30-27-
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n/an/an/an/a>1.00E+4n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384684
PNG
(US10285982, Compound 133)
Show SMILES O=C(Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)-c1ccncc1)C1CCC1
Show InChI InChI=1S/C28H20N8O/c37-28(17-2-1-3-17)33-19-10-18(13-30-14-19)23-12-22-25(15-32-23)35-36-26(22)24-11-21-20(6-9-31-27(21)34-24)16-4-7-29-8-5-16/h4-15,17H,1-3H2,(H,33,37)/b26-24-
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n/an/an/an/a>1.00E+4n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384690
PNG
(US10285982, Compound 182)
Show SMILES C(N1CCCC1)c1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)N1CCCCC1
Show InChI InChI=1S/C28H28N8/c1-2-10-36(11-3-1)26-6-7-30-28-22(26)14-24(32-28)27-21-13-23(31-17-25(21)33-34-27)20-12-19(15-29-16-20)18-35-8-4-5-9-35/h6-7,12-17H,1-5,8-11,18H2/b27-24-
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n/an/an/an/a>1.00E+4n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384696
PNG
(US10285982, Compound 256)
Show SMILES c1c([nH]c2ncccc12)-c1n[nH]c2cnc(cc12)-c1cccnc1
Show InChI InChI=1S/C18H10N6/c1-4-12(9-19-5-1)14-8-13-16(10-21-14)23-24-17(13)15-7-11-3-2-6-20-18(11)22-15/h1-10H/b17-15-
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n/an/an/an/a>1.00E+4n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384699
PNG
(US10285982, Compound 272)
Show SMILES O=C(Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2cccnc2[nH]1)C1CC1
Show InChI InChI=1S/C22H15N7O/c30-22(12-3-4-12)26-15-6-14(9-23-10-15)17-8-16-19(11-25-17)28-29-20(16)18-7-13-2-1-5-24-21(13)27-18/h1-2,5-12H,3-4H2,(H,26,30)/b20-18-
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n/an/an/an/a>1.00E+4n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384715
PNG
(US10285982, Compound 652)
Show SMILES Cn1cc(cn1)-c1cc2c(n[nH]c2cn1)-c1cc2cccnc2[nH]1
Show InChI InChI=1S/C17H11N7/c1-24-9-11(7-20-24)13-6-12-15(8-19-13)22-23-16(12)14-5-10-3-2-4-18-17(10)21-14/h2-9H,1H3/b16-14-
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n/an/an/an/a>1.00E+4n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384716
PNG
(US10285982, Compound 701)
Show SMILES Cc1ncc(-c2cc3c(n[nH]c3cn2)-c2cc3c(ccnc3[nH]2)-c2cccs2)n1C
Show InChI InChI=1S/C22H15N7S/c1-12-24-11-19(29(12)2)16-9-15-18(10-25-16)27-28-21(15)17-8-14-13(20-4-3-7-30-20)5-6-23-22(14)26-17/h3-11H,1-2H3/b21-17-
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n/an/an/an/a 1.06E+3n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384717
PNG
(US10285982, Compound 703)
Show SMILES C1CCC(CC1)Oc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)-c1cccs1
Show InChI InChI=1S/C28H22N6OS/c1-2-5-18(6-3-1)35-19-11-17(14-29-15-19)23-13-22-25(16-31-23)33-34-27(22)24-12-21-20(26-7-4-10-36-26)8-9-30-28(21)32-24/h4,7-16,18H,1-3,5-6H2/b27-24-
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n/an/an/an/a>1.00E+4n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384547
PNG
(US10285982, Compound 1)
Show SMILES CCC(=O)Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)-c1cccc(F)c1
Show InChI InChI=1S/C27H18FN7O/c1-2-25(36)32-18-9-16(12-29-13-18)22-11-21-24(14-31-22)34-35-26(21)23-10-20-19(6-7-30-27(20)33-23)15-4-3-5-17(28)8-15/h3-14H,2H2,1H3,(H,32,36)/b26-23-
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n/an/an/an/a>1.00E+4n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384667
PNG
(US10285982, Compound 62)
Show SMILES CCNCc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)-c1ccccc1F
Show InChI InChI=1S/C27H20FN7/c1-2-29-12-16-9-17(14-30-13-16)23-11-21-25(15-32-23)34-35-26(21)24-10-20-18(7-8-31-27(20)33-24)19-5-3-4-6-22(19)28/h3-11,13-15,29H,2,12H2,1H3/b26-24-
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n/an/an/an/a>1.00E+4n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384683
PNG
(US10285982, Compound 125)
Show SMILES CN(C)Cc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)-c1ccncc1
Show InChI InChI=1S/C26H20N8/c1-34(2)15-16-9-18(13-28-12-16)22-11-21-24(14-30-22)32-33-25(21)23-10-20-19(5-8-29-26(20)31-23)17-3-6-27-7-4-17/h3-14H,15H2,1-2H3/b25-23-
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n/an/an/an/a>1.00E+4n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384685
PNG
(US10285982, Compound 135)
Show SMILES O=C(Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)-c1ccncc1)C1CCCCC1
Show InChI InChI=1S/C30H24N8O/c39-30(19-4-2-1-3-5-19)35-21-12-20(15-32-16-21)25-14-24-27(17-34-25)37-38-28(24)26-13-23-22(8-11-33-29(23)36-26)18-6-9-31-10-7-18/h6-17,19H,1-5H2,(H,35,39)/b28-26-
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n/an/an/an/a>1.00E+4n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
Proto-oncogene Wnt-1


(Homo sapiens (human))
BDBM384687
PNG
(US10285982, Compound 172)
Show SMILES C1CCN(CC1)c1ccnc2[nH]c(cc12)-c1n[nH]c2cnc(cc12)-c1cccnc1
Show InChI InChI=1S/C23H19N7/c1-2-9-30(10-3-1)21-6-8-25-23-17(21)12-19(27-23)22-16-11-18(15-5-4-7-24-13-15)26-14-20(16)28-29-22/h4-8,11-14H,1-3,9-10H2/b22-19-
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n/an/an/an/a 2.24E+3n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...


US Patent US10285982 (2019)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%