Compile Data Set for Download or QSAR
maximum 50k data
Found 8 Enz. Inhib. hit(s) with all data for entry = 2920
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM385383(6-(2-((2,6-Dimethylphenyl)amino)-1H-imidazol-1-yl)...)
Affinity DataIC50:  111nMAssay Description:In some experiments, inhibitory activities of the compounds described herein against select protein kinases were determined as IC50 values (e.g., IC5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM385384(US10287268, Compound I-2 | US10975058, Compound I-...)
Affinity DataIC50:  307nMAssay Description:In some experiments, inhibitory activities of the compounds described herein against select protein kinases were determined as IC50 values (e.g., IC5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM385383(6-(2-((2,6-Dimethylphenyl)amino)-1H-imidazol-1-yl)...)
Affinity DataIC50:  338nMAssay Description:In some experiments, inhibitory activities of the compounds described herein against select protein kinases were determined as IC50 values (e.g., IC5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM385384(US10287268, Compound I-2 | US10975058, Compound I-...)
Affinity DataIC50:  1.86E+3nMAssay Description:In some experiments, inhibitory activities of the compounds described herein against select protein kinases were determined as IC50 values (e.g., IC5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM385385(US10287268, Compound I-3 | US10975058, Compound I-...)
Affinity DataIC50:  2.42E+3nMAssay Description:In some experiments, inhibitory activities of the compounds described herein against select protein kinases were determined as IC50 values (e.g., IC5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM385386(US10287268, Compound I-4 | US10975058, Compound I-...)
Affinity DataIC50:  3.00E+3nMAssay Description:In some experiments, inhibitory activities of the compounds described herein against select protein kinases were determined as IC50 values (e.g., IC5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM385385(US10287268, Compound I-3 | US10975058, Compound I-...)
Affinity DataIC50:  9.98E+3nMAssay Description:In some experiments, inhibitory activities of the compounds described herein against select protein kinases were determined as IC50 values (e.g., IC5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM385386(US10287268, Compound I-4 | US10975058, Compound I-...)
Affinity DataIC50: >1.00E+4nMAssay Description:In some experiments, inhibitory activities of the compounds described herein against select protein kinases were determined as IC50 values (e.g., IC5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent