Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386083![]() (N-((2R,3S)-2-(((cis-4-(2,3- difluorophenyl)cyclohe...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 7.90 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386096![]() (N-(cis-2-(((cis-4- isopropylcyclohexyl)oxy)methyl)...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 880 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386103![]() (US10287305, Example 43 | US10508083, Example 43 | ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386114![]() (US10287305, Example 55 | US10508083, Example 55 | ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 140 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386125![]() (N-(cis-2-(((cis-4- isopropylcyclohexyl)oxy)methyl)...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 750 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386130![]() (N'-(cis-1-acetyl-2-(((cis-4- isopropylcyclohexyl)o...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 63 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386145![]() (US10287305, Example 98 | US10508083, Example 98 | ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 2.90 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386147![]() (US10287305, Example 100 | US10508083, Example 100 ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386154![]() (N,N-dimethyl-N'-(cis-2-(((cis-4- phenylcyclohexyl)...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 480 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386155![]() (N'-(cis-1-acetyl-2-(((cis-4- phenylcyclohexyl)oxy)...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 13 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386177![]() (N-(cis-1-(difluoroacetyl)-2-(((cis- 4-phenylcycloh...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 31 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386187![]() (N-((2R,3S)-1-acetyl-2-(((cis-4-(3- fluorophenyl)cy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386188![]() ((2R,3S)-N-ethyl-2-(((cis-4-(3- fluorophenyl)cycloh...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 0.0530 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386200![]() (US10287305, Example 159 | US10508083, Example 159 ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 140 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386206![]() (N-((2R,3S)-1-(cyanoacetyl)-2- (((cis-4- phenylcycl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 17 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386213![]() (N-((2R,3S)-1-((1- cyanocyclopropyl)carbonyl)-2- ((...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 370 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386257![]() (US10287305, Example 215 | US10508083, Example 215 ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386797![]() (N-(cis-1-((2,2- difluorocyclopropyl)carbonyl)-2- (...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386799![]() (N-(cis-1-butyryl-2-(((1-(2- fluorophenyl)piperidin...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386802![]() (N-(cis-2-(((1-(2- fluorophenyl)piperidin-4- yl)oxy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386806![]() (N-(cis-1-((4,4- difluorocyclohexyl)carbonyl)-2- ((...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386816![]() (US10287305, Example 249 | US10508083, Example 249 ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 0.610 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386818![]() (N-(cis-1-(cyclopropylcarbonyl)-2- (((4-(pyridin-2-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 240 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386829![]() (US10287305, Example 266 | US10508083, Example 266 ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 3.70E+3 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386851![]() (US10287305, Example 295 | US10508083, Example 295 ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 4.20 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386861![]() (US10287305, Example 307 | US10508083, Example 307 ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386864![]() (N'-((2R,3S)-1- (cyclopropylcarbonyl)-2-(((cis-4- p...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386878![]() (N-(cis-1-(cyclopropylcarbonyl)-2- (((4-(3,5-difluo...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386882![]() (N-(cis-2-(((cis-4-(2- chlorophenyl)cyclohexyl)oxy)...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 610 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386884![]() (N-(cis-1-acetyl-2-(((cis-4-(2- chlorophenyl)cycloh...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 27 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386887![]() (US10287305, Example 338 | US10508083, Example 338 ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 490 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386893![]() (US10287305, Example 344 | US10508083, Example 344 ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 290 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386898![]() (N-(cis-2-(((cis-4- phenylcyclohexyl)oxy)methyl)- p...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386901![]() (US10287305, Example 356 | US10508083, Example 356 ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 21 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386064![]() ((2R,3S)-N-ethyl-2-(((cis-4- isopropylcyclohexyl)ox...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386069![]() (N-((2R,3S)-1-acetyl-2-(((cis-4- (3,5- difluorophen...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 5.60 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386086![]() (N-((2R,3S)-1-(cyclopropylcarbonyl)- 2-(((cis-4-(2-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386089![]() (N-((2R,3S)-1-(cyclopropylcarbonyl)- 2-(((cis-4- ph...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 0.660 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386102![]() (US10287305, Example 42 | US10508083, Example 42 | ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 210 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386109![]() (N-(cis-2-(((cis-4- isopropylcyclohexyl)oxy)methyl)...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 330 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386120![]() (N-((2R,3S)-1-acetyl-2-(((cis-4- isopropylcyclohexy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 97 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386134![]() (N-((2R,3S)-2-(((cis-4- isopropylcyclohexyl)oxy)met...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 840 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386137![]() (N-((2R,3S)-2-(((cis-4- isopropylcyclohexyl)oxy)met...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 39 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386148![]() (US10287305, Example 101 | US10508083, Example 101 ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386149![]() ((2R,3S)-2-(((cis-4- isopropylcyclohexyl)oxy)methyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386152![]() (N-(cis-1-acetyl-2-(((cis-4- (trifluoromethyl)cyclo...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 4.80E+3 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386158![]() (N-(cis-1-acetyl-2-(((cis-3- phenylcyclobutyl)oxy)m...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386164![]() (N-(cis-1-(methoxyacetyl)-2-(((cis-4- phenylcyclohe...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 30 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386179![]() (N-(cis-1-acetyl-2-(((cis-4-(3,4- difluorophenyl)cy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 460 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM386189![]() (N-(cis-2-(((cis-4- phenylcyclohexyl)oxy)methyl)-1-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 25 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ... | US Patent US10287305 (2019) BindingDB Entry DOI: 10.7270/Q2Z321Z2 | |||||||||||
More data for this Ligand-Target Pair |
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