Search and Browse
Download
Enter Data
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TGF-beta receptor type I (Homo sapiens (Human)) | BDBM387321 (2-methyl-6-(4-{1H-pyrrolo[3,2-c]pyridin-1-yl}pyrro...) | PDB KEGG B.MOAD GoogleScholar | UniChem | US Patent | n/a | n/a | 0.960 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10292985 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type I (Homo sapiens (Human)) | BDBM387324 (2-(4-{1H-pyrrolo[3,2-c]pyridin-1-yl}pyrrolo[2,1-f]...) | PDB KEGG B.MOAD GoogleScholar | UniChem | US Patent | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10292985 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type I (Homo sapiens (Human)) | BDBM387329 (7-methoxy-N-[2-(6-methylpyridin-2-yl)pyrrolo[2,1-f...) | PDB KEGG B.MOAD GoogleScholar | UniChem | US Patent | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10292985 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type I (Homo sapiens (Human)) | BDBM387344 (2-ethyl-6-(4-{1H-pyrrolo[3,2-c]pyridin-1-yl}pyrrol...) | PDB KEGG B.MOAD GoogleScholar | UniChem | US Patent | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10292985 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type I (Homo sapiens (Human)) | BDBM387340 (3-fluoro-2-methyl-6-(4-{1H-pyrrolo[3,2-c]pyridin-1...) | PDB KEGG B.MOAD GoogleScholar | UniChem | US Patent | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10292985 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type I (Homo sapiens (Human)) | BDBM387345 (2-cyclopropyl-6-(4-{1H-pyrrolo[3,2-c]pyridin-1-yl}...) | PDB KEGG B.MOAD GoogleScholar | UniChem | US Patent | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10292985 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type I (Homo sapiens (Human)) | BDBM387333 (N-[2-(6-methylpyridin-2-yl)pyrrolo[2,1-f][1,2,4]tr...) | PDB KEGG B.MOAD GoogleScholar | UniChem | US Patent | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10292985 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type I (Homo sapiens (Human)) | BDBM387322 (2-fluoro-6-(4-{1H-pyrrolo[3,2-c]pyridin-1-yl}pyrro...) | PDB KEGG B.MOAD GoogleScholar | UniChem | US Patent | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10292985 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type I (Homo sapiens (Human)) | BDBM387354 (N-[2-(6-methylpyridin-2-yl)pyrrolo[2,1-f][1,2,4]tr...) | PDB KEGG B.MOAD GoogleScholar | UniChem | US Patent | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10292985 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type I (Homo sapiens (Human)) | BDBM387338 (N-{2-[6-(difluoromethyl)pyridin-2-yl]pyrrolo[2,1-f...) | PDB KEGG B.MOAD GoogleScholar | UniChem | US Patent | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10292985 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type I (Homo sapiens (Human)) | BDBM387353 (2-(methylsulfanyl)-4-(4-{1H-pyrrolo[3,2-c]pyridin-...) | PDB KEGG B.MOAD GoogleScholar | UniChem | US Patent | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10292985 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type I (Homo sapiens (Human)) | BDBM387347 (2-(difluoromethyl)-6-(4-{1H-pyrrolo[3,2-c]pyridin-...) | PDB KEGG B.MOAD GoogleScholar | UniChem | US Patent | n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10292985 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type I (Homo sapiens (Human)) | BDBM387346 (2-(4-{1H-pyrrolo[3,2-c]pyridin-1-yl}pyrrolo[2,1-f]...) | PDB KEGG B.MOAD GoogleScholar | UniChem | US Patent | n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10292985 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type I (Homo sapiens (Human)) | BDBM387337 (7-methoxy-N-{2-[6-(trifluoromethyl)pyridin-2-yl]py...) | PDB KEGG B.MOAD GoogleScholar | UniChem | US Patent | n/a | n/a | 4.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10292985 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type I (Homo sapiens (Human)) | BDBM387334 (N-[2-(6-methylpyridin-2-yl)pyrrolo[2,1-f][1,2,4]tr...) | PDB KEGG B.MOAD GoogleScholar | UniChem | US Patent | n/a | n/a | 4.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10292985 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type I (Homo sapiens (Human)) | BDBM387331 (6-chloro-N-[2-(6-methylpyridin-2-yl)pyrrolo[2,1-f]...) | PDB KEGG B.MOAD GoogleScholar | UniChem | US Patent | n/a | n/a | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10292985 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type I (Homo sapiens (Human)) | BDBM387349 (2-chloro-6-(4-{1H-pyrrolo[3,2-c]pyridin-1}-yl pyrr...) | PDB KEGG B.MOAD GoogleScholar | UniChem | US Patent | n/a | n/a | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10292985 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type I (Homo sapiens (Human)) | BDBM387325 (2-(4-{1H-imidazo[4,5-c]pyridin-1-yl}pyrrolo[2,1-f]...) | PDB KEGG B.MOAD GoogleScholar | UniChem | US Patent | n/a | n/a | 5.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10292985 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type I (Homo sapiens (Human)) | BDBM387335 (N-[2-(6-methylpyridin-2-yl)pyrrolo[2,1-f][1,2,4]tr...) | PDB KEGG B.MOAD GoogleScholar | UniChem | US Patent | n/a | n/a | 5.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10292985 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type I (Homo sapiens (Human)) | BDBM387339 (N-{2-[6-(difluoromethyl)pyridin-2-yl]pyrrolo[2,1-f...) | PDB KEGG B.MOAD GoogleScholar | UniChem | US Patent | n/a | n/a | 5.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10292985 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type I (Homo sapiens (Human)) | BDBM387350 (2-methoxy-6-(4-{1H-pyrrolo[3,2-c]pyridin-1-yl}pyrr...) | PDB KEGG B.MOAD GoogleScholar | UniChem | US Patent | n/a | n/a | 6.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10292985 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type I (Homo sapiens (Human)) | BDBM387327 (6-methoxy-N-[2-(6-methylpyridin-2-yl)pyrrolo[2,1-f...) | PDB KEGG B.MOAD GoogleScholar | UniChem | US Patent | n/a | n/a | 6.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10292985 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type I (Homo sapiens (Human)) | BDBM387330 (6-fluoro-N-[2-(6-methylpyridin-2-yl)pyrrolo[2,1-f]...) | PDB KEGG B.MOAD GoogleScholar | UniChem | US Patent | n/a | n/a | 6.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10292985 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type I (Homo sapiens (Human)) | BDBM387342 (2-(5-chloro-4-{1H-pyrrolo[3,2-c]pyridin-1-yl}pyrro...) | PDB KEGG B.MOAD GoogleScholar | UniChem | US Patent | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10292985 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type I (Homo sapiens (Human)) | BDBM387352 (5-methyl-2-(4-{1H-pyrrolo[3,2-c]pyridin-1-yl}pyrro...) | PDB KEGG B.MOAD GoogleScholar | UniChem | US Patent | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10292985 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type I (Homo sapiens (Human)) | BDBM387320 (3-fluoro-6-methyl-2-(4-{1H-pyrrolo[3,2-c]pyridin-1...) | PDB KEGG B.MOAD GoogleScholar | UniChem | US Patent | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10292985 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type I (Homo sapiens (Human)) | BDBM387318 (N-{2-[6-(trifluoromethyl)pyridin-2-yl]pyrrolo[2,1-...) | PDB KEGG B.MOAD GoogleScholar | UniChem | US Patent | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10292985 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type I (Homo sapiens (Human)) | BDBM387351 (5-fluoro-2-(4-{1H-pyrrolo[3,2-c]pyridin-1-yl}pyrro...) | PDB KEGG B.MOAD GoogleScholar | UniChem | US Patent | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10292985 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type I (Homo sapiens (Human)) | BDBM387317 (N-[2-(6-methylpyridin-2-yl)pyrrolo[2,1-f][1,2,4]tr...) | PDB KEGG B.MOAD GoogleScholar | UniChem | US Patent | n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10292985 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type I (Homo sapiens (Human)) | BDBM387343 (N-[6-(4-{1H-pyrrolo[3,2-c]pyridin-1-yl}pyrrolo[2,1...) | PDB KEGG B.MOAD GoogleScholar | UniChem | US Patent | n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10292985 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type II (Homo sapiens (Human)) | BDBM387351 (5-fluoro-2-(4-{1H-pyrrolo[3,2-c]pyridin-1-yl}pyrro...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | UniChem | US Patent | n/a | n/a | 39 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | US Patent US10292985 (2019) | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type II (Homo sapiens (Human)) | BDBM387324 (2-(4-{1H-pyrrolo[3,2-c]pyridin-1-yl}pyrrolo[2,1-f]...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | UniChem | US Patent | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | US Patent US10292985 (2019) | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type I (Homo sapiens (Human)) | BDBM387348 (2-methoxy-6-(4-{1H-pyrazolo[4,3-c]pyridin-1-yl}pyr...) | PDB KEGG B.MOAD GoogleScholar | UniChem | US Patent | n/a | n/a | 67 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10292985 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type II (Homo sapiens (Human)) | BDBM387322 (2-fluoro-6-(4-{1H-pyrrolo[3,2-c]pyridin-1-yl}pyrro...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | UniChem | US Patent | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | US Patent US10292985 (2019) | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type I (Homo sapiens (Human)) | BDBM387323 (1-methyl-N-[2-(pyridin-2-yl)pyrrolo[2,1-f][1,2,4]t...) | PDB KEGG B.MOAD GoogleScholar | UniChem | US Patent | n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10292985 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type II (Homo sapiens (Human)) | BDBM387321 (2-methyl-6-(4-{1H-pyrrolo[3,2-c]pyridin-1-yl}pyrro...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | UniChem | US Patent | n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | US Patent US10292985 (2019) | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type I (Homo sapiens (Human)) | BDBM387328 (6-bromo-N-[2-(6-methylpyridin-2-yl)pyrrolo[2,1-f][...) | PDB KEGG B.MOAD GoogleScholar | UniChem | US Patent | n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10292985 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type I (Homo sapiens (Human)) | BDBM387326 (2-(4-{1H-pyrrolo[2,3-c]pyridin-1-yl}pyrrolo[2,1-f]...) | PDB KEGG B.MOAD GoogleScholar | UniChem | US Patent | n/a | n/a | 310 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10292985 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type II (Homo sapiens (Human)) | BDBM387349 (2-chloro-6-(4-{1H-pyrrolo[3,2-c]pyridin-1}-yl pyrr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | UniChem | US Patent | n/a | n/a | 490 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | US Patent US10292985 (2019) | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type II (Homo sapiens (Human)) | BDBM387340 (3-fluoro-2-methyl-6-(4-{1H-pyrrolo[3,2-c]pyridin-1...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | UniChem | US Patent | n/a | n/a | 690 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | US Patent US10292985 (2019) | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type II (Homo sapiens (Human)) | BDBM387352 (5-methyl-2-(4-{1H-pyrrolo[3,2-c]pyridin-1-yl}pyrro...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | UniChem | US Patent | n/a | n/a | 820 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | US Patent US10292985 (2019) | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type II (Homo sapiens (Human)) | BDBM387333 (N-[2-(6-methylpyridin-2-yl)pyrrolo[2,1-f][1,2,4]tr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | UniChem | US Patent | n/a | n/a | 930 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | US Patent US10292985 (2019) | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type I (Homo sapiens (Human)) | BDBM387332 (N-[2-(6-methylpyridin-2-yl)pyrrolo[2,1-f][1,2,4]tr...) | PDB KEGG B.MOAD GoogleScholar | UniChem | US Patent | n/a | n/a | 940 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10292985 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type II (Homo sapiens (Human)) | BDBM387329 (7-methoxy-N-[2-(6-methylpyridin-2-yl)pyrrolo[2,1-f...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | UniChem | US Patent | n/a | n/a | 950 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | US Patent US10292985 (2019) | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type II (Homo sapiens (Human)) | BDBM387325 (2-(4-{1H-imidazo[4,5-c]pyridin-1-yl}pyrrolo[2,1-f]...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | UniChem | US Patent | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | US Patent US10292985 (2019) | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type II (Homo sapiens (Human)) | BDBM387344 (2-ethyl-6-(4-{1H-pyrrolo[3,2-c]pyridin-1-yl}pyrrol...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | UniChem | US Patent | n/a | n/a | 1.27E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | US Patent US10292985 (2019) | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type II (Homo sapiens (Human)) | BDBM387347 (2-(difluoromethyl)-6-(4-{1H-pyrrolo[3,2-c]pyridin-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | UniChem | US Patent | n/a | n/a | 1.66E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | US Patent US10292985 (2019) | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type II (Homo sapiens (Human)) | BDBM387317 (N-[2-(6-methylpyridin-2-yl)pyrrolo[2,1-f][1,2,4]tr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | UniChem | US Patent | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | US Patent US10292985 (2019) | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type II (Homo sapiens (Human)) | BDBM387335 (N-[2-(6-methylpyridin-2-yl)pyrrolo[2,1-f][1,2,4]tr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | UniChem | US Patent | n/a | n/a | 2.32E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | US Patent US10292985 (2019) | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type II (Homo sapiens (Human)) | BDBM387328 (6-bromo-N-[2-(6-methylpyridin-2-yl)pyrrolo[2,1-f][...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | UniChem | US Patent | n/a | n/a | 3.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | US Patent US10292985 (2019) | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type II (Homo sapiens (Human)) | BDBM387338 (N-{2-[6-(difluoromethyl)pyridin-2-yl]pyrrolo[2,1-f...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | UniChem | US Patent | n/a | n/a | 3.12E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | US Patent US10292985 (2019) | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type II (Homo sapiens (Human)) | BDBM387353 (2-(methylsulfanyl)-4-(4-{1H-pyrrolo[3,2-c]pyridin-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | UniChem | US Patent | n/a | n/a | 5.46E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | US Patent US10292985 (2019) | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type II (Homo sapiens (Human)) | BDBM387334 (N-[2-(6-methylpyridin-2-yl)pyrrolo[2,1-f][1,2,4]tr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | UniChem | US Patent | n/a | n/a | 7.64E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | US Patent US10292985 (2019) | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type II (Homo sapiens (Human)) | BDBM387327 (6-methoxy-N-[2-(6-methylpyridin-2-yl)pyrrolo[2,1-f...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | UniChem | US Patent | n/a | n/a | 8.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | US Patent US10292985 (2019) | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type II (Homo sapiens (Human)) | BDBM387326 (2-(4-{1H-pyrrolo[2,3-c]pyridin-1-yl}pyrrolo[2,1-f]...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | UniChem | US Patent | n/a | n/a | 1.25E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | US Patent US10292985 (2019) | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type I (Homo sapiens (Human)) | BDBM387319 (N-(2-(6-methoxypyridin-2-yl)pyrrolo[2,1-f][1,2,4]t...) | PDB KEGG B.MOAD GoogleScholar | UniChem | US Patent | n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec... | US Patent US10292985 (2019) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type II (Homo sapiens (Human)) | BDBM387337 (7-methoxy-N-{2-[6-(trifluoromethyl)pyridin-2-yl]py...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | UniChem | US Patent | n/a | n/a | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | US Patent US10292985 (2019) | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type II (Homo sapiens (Human)) | BDBM387346 (2-(4-{1H-pyrrolo[3,2-c]pyridin-1-yl}pyrrolo[2,1-f]...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | UniChem | US Patent | n/a | n/a | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | US Patent US10292985 (2019) | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type II (Homo sapiens (Human)) | BDBM387320 (3-fluoro-6-methyl-2-(4-{1H-pyrrolo[3,2-c]pyridin-1...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | UniChem | US Patent | n/a | n/a | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | US Patent US10292985 (2019) | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type II (Homo sapiens (Human)) | BDBM387319 (N-(2-(6-methoxypyridin-2-yl)pyrrolo[2,1-f][1,2,4]t...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | UniChem | US Patent | n/a | n/a | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | US Patent US10292985 (2019) | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type II (Homo sapiens (Human)) | BDBM387330 (6-fluoro-N-[2-(6-methylpyridin-2-yl)pyrrolo[2,1-f]...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | UniChem | US Patent | n/a | n/a | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | US Patent US10292985 (2019) | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type II (Homo sapiens (Human)) | BDBM387345 (2-cyclopropyl-6-(4-{1H-pyrrolo[3,2-c]pyridin-1-yl}...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | UniChem | US Patent | n/a | n/a | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | US Patent US10292985 (2019) | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type II (Homo sapiens (Human)) | BDBM387348 (2-methoxy-6-(4-{1H-pyrazolo[4,3-c]pyridin-1-yl}pyr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | UniChem | US Patent | n/a | n/a | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | US Patent US10292985 (2019) | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type II (Homo sapiens (Human)) | BDBM387332 (N-[2-(6-methylpyridin-2-yl)pyrrolo[2,1-f][1,2,4]tr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | UniChem | US Patent | n/a | n/a | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | US Patent US10292985 (2019) | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type II (Homo sapiens (Human)) | BDBM387331 (6-chloro-N-[2-(6-methylpyridin-2-yl)pyrrolo[2,1-f]...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | UniChem | US Patent | n/a | n/a | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | US Patent US10292985 (2019) | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type II (Homo sapiens (Human)) | BDBM387350 (2-methoxy-6-(4-{1H-pyrrolo[3,2-c]pyridin-1-yl}pyrr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | UniChem | US Patent | n/a | n/a | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | US Patent US10292985 (2019) | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type II (Homo sapiens (Human)) | BDBM387318 (N-{2-[6-(trifluoromethyl)pyridin-2-yl]pyrrolo[2,1-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | UniChem | US Patent | n/a | n/a | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | US Patent US10292985 (2019) | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type II (Homo sapiens (Human)) | BDBM387354 (N-[2-(6-methylpyridin-2-yl)pyrrolo[2,1-f][1,2,4]tr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | UniChem | US Patent | n/a | n/a | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | US Patent US10292985 (2019) | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type II (Homo sapiens (Human)) | BDBM387342 (2-(5-chloro-4-{1H-pyrrolo[3,2-c]pyridin-1-yl}pyrro...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | UniChem | US Patent | n/a | n/a | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | US Patent US10292985 (2019) | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type II (Homo sapiens (Human)) | BDBM387343 (N-[6-(4-{1H-pyrrolo[3,2-c]pyridin-1-yl}pyrrolo[2,1...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | UniChem | US Patent | n/a | n/a | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | US Patent US10292985 (2019) | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type II (Homo sapiens (Human)) | BDBM387339 (N-{2-[6-(difluoromethyl)pyridin-2-yl]pyrrolo[2,1-f...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | UniChem | US Patent | n/a | n/a | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | US Patent US10292985 (2019) | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| TGF-beta receptor type II (Homo sapiens (Human)) | BDBM387323 (1-methyl-N-[2-(pyridin-2-yl)pyrrolo[2,1-f][1,2,4]t...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | UniChem | US Patent | n/a | n/a | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | US Patent US10292985 (2019) | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
