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Patent code US10294212

Compile Data Set for Download or QSAR

Found 277 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387580
PNG
(4-(2-Amino-3- ((3-chloro-4- fluorophenyl) amino)-5...)
Show SMILES COc1cc2c(Nc3ccc(F)c(Cl)c3)c(N)oc2c(n1)-c1ccc(cc1)C#N
Show InChI InChI=1S/C21H14ClFN4O2/c1-28-17-9-14-19(26-13-6-7-16(23)15(22)8-13)21(25)29-20(14)18(27-17)12-4-2-11(10-24)3-5-12/h2-9,26H,25H2,1H3
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n/an/a<200n/an/an/an/an/an/a



CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387607
PNG
(N3-(3-Chloro-4- fluorophenyl)- 7-(2,6- difluoro- p...)
Show SMILES Nc1oc2c(nccc2c1Nc1ccc(F)c(Cl)c1)-c1cc(F)nc(F)c1
Show InChI InChI=1S/C18H10ClF3N4O/c19-11-7-9(1-2-12(11)20)25-16-10-3-4-24-15(17(10)27-18(16)23)8-5-13(21)26-14(22)6-8/h1-7,25H,23H2
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n/an/a<200n/an/an/an/an/an/a



CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387630
PNG
(N3-(3-Chloro-4- fluorophenyl)- 7-(pyridin-4- yl)be...)
Show SMILES Nc1sc2c(cccc2c1Nc1ccc(F)c(Cl)c1)-c1ccncc1
Show InChI InChI=1S/C19H13ClFN3S/c20-15-10-12(4-5-16(15)21)24-17-14-3-1-2-13(18(14)25-19(17)22)11-6-8-23-9-7-11/h1-10,24H,22H2
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CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387640
PNG
(5-Fluoro-N3-(3- (trifluoro- methyl)phenyl) furo[2,...)
Show SMILES Nc1oc2cnc(F)cc2c1Nc1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C14H9F4N3O/c15-11-5-9-10(6-20-11)22-13(19)12(9)21-8-3-1-2-7(4-8)14(16,17)18/h1-6,21H,19H2
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CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387642
PNG
(4-(2-Amino-3- ((3,4- difluorophenyl) amino)furo[2,...)
Show SMILES CNC(=O)c1cc(ccn1)-c1nccc2c(Nc3ccc(F)c(F)c3)c(N)oc12
Show InChI InChI=1S/C20H15F2N5O2/c1-24-20(28)15-8-10(4-6-25-15)16-18-12(5-7-26-16)17(19(23)29-18)27-11-2-3-13(21)14(22)9-11/h2-9,27H,23H2,1H3,(H,24,28)
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n/an/a<200n/an/an/an/an/an/a



CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387658
PNG
(7-(2- Methylpyridin- 4-yl)-N3- phenylfuro[2,3- c]p...)
Show SMILES Cc1cc(ccn1)-c1nccc2c(Nc3ccccc3)c(N)oc12
Show InChI InChI=1S/C19H16N4O/c1-12-11-13(7-9-21-12)16-18-15(8-10-22-16)17(19(20)24-18)23-14-5-3-2-4-6-14/h2-11,23H,20H2,1H3
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CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387659
PNG
(N3-(3-Chloro-4- fluorophenyl)- 7-(2- methylpyridin...)
Show SMILES Cc1cc(ccn1)-c1cccc2c(Nc3ccc(F)c(Cl)c3)c(N)sc12
Show InChI InChI=1S/C20H15ClFN3S/c1-11-9-12(7-8-24-11)14-3-2-4-15-18(20(23)26-19(14)15)25-13-5-6-17(22)16(21)10-13/h2-10,25H,23H2,1H3
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CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387673
PNG
(4-(2-Amino-3- ((3-chloro-4- fluorophenyl) amino)fu...)
Show SMILES CC(C)(C)NC(=O)c1cc(ccn1)-c1nccc2c(Nc3ccc(F)c(Cl)c3)c(N)oc12
Show InChI InChI=1S/C23H21ClFN5O2/c1-23(2,3)30-22(31)17-10-12(6-8-27-17)18-20-14(7-9-28-18)19(21(26)32-20)29-13-4-5-16(25)15(24)11-13/h4-11,29H,26H2,1-3H3,(H,30,31)
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n/an/a<200n/an/an/an/an/an/a



CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387689
PNG
(N3-(3-Chloro-4- fluorophenyl)- 7-(2- (trifluoro- m...)
Show SMILES Nc1oc2c(nccc2c1Nc1ccc(F)c(Cl)c1)-c1ccnc(c1)C(F)(F)F
Show InChI InChI=1S/C19H11ClF4N4O/c20-12-8-10(1-2-13(12)21)28-16-11-4-6-27-15(17(11)29-18(16)25)9-3-5-26-14(7-9)19(22,23)24/h1-8,28H,25H2
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CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387700
PNG
(N3-(3-Chloro-4- fluorophenyl)- 7-styrylfuro [2,3-c...)
Show SMILES Nc1oc2c(\C=C\c3ccccc3)nccc2c1Nc1ccc(F)c(Cl)c1
Show InChI InChI=1S/C21H15ClFN3O/c22-16-12-14(7-8-17(16)23)26-19-15-10-11-25-18(20(15)27-21(19)24)9-6-13-4-2-1-3-5-13/h1-12,26H,24H2/b9-6+
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CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387401
PNG
(N3-(3- Cyclopropyl- phenyl)furo [2,3-c] pyridine-2...)
Show SMILES Nc1oc2cnccc2c1Nc1cccc(c1)C1CC1
Show InChI InChI=1S/C16H15N3O/c17-16-15(13-6-7-18-9-14(13)20-16)19-12-3-1-2-11(8-12)10-4-5-10/h1-3,6-10,19H,4-5,17H2
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CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387448
PNG
(7-Phenyl-N3- (3-(trifluoro- methyl)phenyl) furo[2,...)
Show SMILES Nc1oc2c(nccc2c1Nc1cccc(c1)C(F)(F)F)-c1ccccc1
Show InChI InChI=1S/C20H14F3N3O/c21-20(22,23)13-7-4-8-14(11-13)26-17-15-9-10-25-16(18(15)27-19(17)24)12-5-2-1-3-6-12/h1-11,26H,24H2
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CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387478
PNG
(2-Amino-3-((3- chloro-4- fluorophenyl) amino)furo ...)
Show SMILES Nc1oc2c(nccc2c1Nc1ccc(F)c(Cl)c1)C#N
Show InChI InChI=1S/C14H8ClFN4O/c15-9-5-7(1-2-10(9)16)20-12-8-3-4-19-11(6-17)13(8)21-14(12)18/h1-5,20H,18H2
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CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387490
PNG
(2-Amino-3-((3- bromophenyl) amino) benzofuran-6- c...)
Show SMILES Nc1oc2cc(ccc2c1Nc1cccc(Br)c1)C#N
Show InChI InChI=1S/C15H10BrN3O/c16-10-2-1-3-11(7-10)19-14-12-5-4-9(8-17)6-13(12)20-15(14)18/h1-7,19H,18H2
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CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387558
PNG
(4-(2-Amino-3- ((3-chloro-4- fluorophenyl) amino)fu...)
Show SMILES NC(=O)c1ccc(cc1)-c1nccc2c(Nc3ccc(F)c(Cl)c3)c(N)oc12
Show InChI InChI=1S/C20H14ClFN4O2/c21-14-9-12(5-6-15(14)22)26-17-13-7-8-25-16(18(13)28-20(17)24)10-1-3-11(4-2-10)19(23)27/h1-9,26H,24H2,(H2,23,27)
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n/an/a<200n/an/an/an/an/an/a



CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387586
PNG
(5-Chloro-N3- (3-chloro-4- fluorophenyl) furo[2,3-c...)
Show SMILES Nc1oc2cnc(Cl)cc2c1Nc1ccc(F)c(Cl)c1
Show InChI InChI=1S/C13H8Cl2FN3O/c14-8-3-6(1-2-9(8)16)19-12-7-4-11(15)18-5-10(7)20-13(12)17/h1-5,19H,17H2
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CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387589
PNG
(N3-(3-Chloro-4- fluorophenyl)- 5-fluorofuro [2,3-c...)
Show SMILES Nc1oc2cnc(F)cc2c1Nc1ccc(F)c(Cl)c1
Show InChI InChI=1S/C13H8ClF2N3O/c14-8-3-6(1-2-9(8)15)19-12-7-4-11(16)18-5-10(7)20-13(12)17/h1-5,19H,17H2
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CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387623
PNG
(N3-(2- chlorophenyl)- 7-(2-methyl- pyridin-4-yl) f...)
Show SMILES Cc1cc(ccn1)-c1nccc2c(Nc3ccccc3Cl)c(N)oc12
Show InChI InChI=1S/C19H15ClN4O/c1-11-10-12(6-8-22-11)16-18-13(7-9-23-16)17(19(21)25-18)24-15-5-3-2-4-14(15)20/h2-10,24H,21H2,1H3
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CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387644
PNG
(4-(2-Amino-3- ((3- chlorophenyl) amino)furo[2,3- c...)
Show SMILES CNC(=O)c1cc(ccn1)-c1nccc2c(Nc3cccc(Cl)c3)c(N)oc12
Show InChI InChI=1S/C20H16ClN5O2/c1-23-20(27)15-9-11(5-7-24-15)16-18-14(6-8-25-16)17(19(22)28-18)26-13-4-2-3-12(21)10-13/h2-10,26H,22H2,1H3,(H,23,27)
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CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387646
PNG
(4-(2-amino-3- ((4-fluoro-3- (trifluoro- methyl)phe...)
Show SMILES CNC(=O)c1cc(ccn1)-c1nccc2c(Nc3ccc(F)c(c3)C(F)(F)F)c(N)oc12
Show InChI InChI=1S/C21H15F4N5O2/c1-27-20(31)15-8-10(4-6-28-15)16-18-12(5-7-29-16)17(19(26)32-18)30-11-2-3-14(22)13(9-11)21(23,24)25/h2-9,30H,26H2,1H3,(H,27,31)
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n/an/a<200n/an/an/an/an/an/a



CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387668
PNG
(N3-(3,4- Difluoro- phenyl)-5- fluoro-7-(2- methylp...)
Show SMILES Cc1cc(ccn1)-c1nc(F)cc2c(Nc3ccc(F)c(F)c3)c(N)oc12
Show InChI InChI=1S/C19H13F3N4O/c1-9-6-10(4-5-24-9)16-18-12(8-15(22)26-16)17(19(23)27-18)25-11-2-3-13(20)14(21)7-11/h2-8,25H,23H2,1H3
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CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387669
PNG
(N3-(3-Chloro-4- fluorophenyl)- 7-(naphthalen- 2-yl...)
Show SMILES Nc1oc2c(nccc2c1Nc1ccc(F)c(Cl)c1)-c1ccc2ccccc2c1
Show InChI InChI=1S/C23H15ClFN3O/c24-18-12-16(7-8-19(18)25)28-21-17-9-10-27-20(22(17)29-23(21)26)15-6-5-13-3-1-2-4-14(13)11-15/h1-12,28H,26H2
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n/an/a<200n/an/an/an/an/an/a



CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387695
PNG
(4-(2-Amino-3- ((3-chloro-4- fluorophenyl) amino)fu...)
Show SMILES CCCCCNC(=O)c1cc(ccn1)-c1nccc2c(Nc3ccc(F)c(Cl)c3)c(N)oc12
Show InChI InChI=1S/C24H23ClFN5O2/c1-2-3-4-9-30-24(32)19-12-14(7-10-28-19)20-22-16(8-11-29-20)21(23(27)33-22)31-15-5-6-18(26)17(25)13-15/h5-8,10-13,31H,2-4,9,27H2,1H3,(H,30,32)
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n/an/a<200n/an/an/an/an/an/a



CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387429
PNG
(N3-(3-Chloro-4- fluorophenyl)- 5- methoxyfuro [2,3...)
Show SMILES COc1cc2c(Nc3ccc(F)c(Cl)c3)c(N)oc2cn1
Show InChI InChI=1S/C14H11ClFN3O2/c1-20-12-5-8-11(6-18-12)21-14(17)13(8)19-7-2-3-10(16)9(15)4-7/h2-6,19H,17H2,1H3
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CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387430
PNG
(N3-(3- (Difluoro- methyl) phenyl)furo [2,3-c]pyrid...)
Show SMILES Nc1oc2cnccc2c1Nc1cccc(c1)C(F)F
Show InChI InChI=1S/C14H11F2N3O/c15-13(16)8-2-1-3-9(6-8)19-12-10-4-5-18-7-11(10)20-14(12)17/h1-7,13,19H,17H2
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CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387444
PNG
(7-Propyl-N3-(3- (trifluoro- methyl)phenyl) furo[2,...)
Show SMILES CCCc1nccc2c(Nc3cccc(c3)C(F)(F)F)c(N)oc12
Show InChI InChI=1S/C17H16F3N3O/c1-2-4-13-15-12(7-8-22-13)14(16(21)24-15)23-11-6-3-5-10(9-11)17(18,19)20/h3,5-9,23H,2,4,21H2,1H3
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CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387465
PNG
(N3-(3-Chloro-4- fluorophenyl)- 7-(pyridin-3- yl)fu...)
Show SMILES Nc1oc2c(nccc2c1Nc1ccc(F)c(Cl)c1)-c1cccnc1
Show InChI InChI=1S/C18H12ClFN4O/c19-13-8-11(3-4-14(13)20)24-16-12-5-7-23-15(17(12)25-18(16)21)10-2-1-6-22-9-10/h1-9,24H,21H2
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CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387554
PNG
(N3-(3- Chloro-4- fluorophenyl)- 7-(1-methyl- 1H-py...)
Show SMILES Cn1cc(cn1)-c1nccc2c(Nc3ccc(F)c(Cl)c3)c(N)oc12
Show InChI InChI=1S/C17H13ClFN5O/c1-24-8-9(7-22-24)14-16-11(4-5-21-14)15(17(20)25-16)23-10-2-3-13(19)12(18)6-10/h2-8,23H,20H2,1H3
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CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387557
PNG
(4-(2-Amino-3- ((3-chloro-4- fluorophenyl) amino)fu...)
Show SMILES Nc1oc2c(nccc2c1Nc1ccc(F)c(Cl)c1)-c1ccc(cc1)C#N
Show InChI InChI=1S/C20H12ClFN4O/c21-15-9-13(5-6-16(15)22)26-18-14-7-8-25-17(19(14)27-20(18)24)12-3-1-11(10-23)2-4-12/h1-9,26H,24H2
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CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387431
PNG
(N3-(3-Chloro-4- fluorophenyl)- 7-methylfuro [2,3-c...)
Show SMILES Cc1nccc2c(Nc3ccc(F)c(Cl)c3)c(N)oc12
Show InChI InChI=1S/C14H11ClFN3O/c1-7-13-9(4-5-18-7)12(14(17)20-13)19-8-2-3-11(16)10(15)6-8/h2-6,19H,17H2,1H3
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CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387574
PNG
(7-Chloro-N3- (3-chloro-4- fluorophenyl) furo[2,3-c...)
Show SMILES Nc1oc2c(Cl)nccc2c1Nc1ccc(F)c(Cl)c1
Show InChI InChI=1S/C13H8Cl2FN3O/c14-8-5-6(1-2-9(8)16)19-10-7-3-4-18-12(15)11(7)20-13(10)17/h1-5,19H,17H2
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CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387585
PNG
(N3-(3-chloro-4- fluorophenyl)- 7-fluorofuro [2,3-c...)
Show SMILES Nc1oc2c(F)nccc2c1Nc1ccc(F)c(Cl)c1
Show InChI InChI=1S/C13H8ClF2N3O/c14-8-5-6(1-2-9(8)15)19-10-7-3-4-18-12(16)11(7)20-13(10)17/h1-5,19H,17H2
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CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387591
PNG
(2-Amino-3- ((4-fluoro-3- (trifluoro- methyl)phenyl...)
Show SMILES Nc1oc2c(nccc2c1Nc1ccc(F)c(c1)C(F)(F)F)C#N
Show InChI InChI=1S/C15H8F4N4O/c16-10-2-1-7(5-9(10)15(17,18)19)23-12-8-3-4-22-11(6-20)13(8)24-14(12)21/h1-5,23H,21H2
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CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387605
PNG
(7-Fluoro-N3- (4-fluoro-3- (trifluoro- methyl)pheny...)
Show SMILES Nc1oc2c(F)nccc2c1Nc1ccc(F)c(c1)C(F)(F)F
Show InChI InChI=1S/C14H8F5N3O/c15-9-2-1-6(5-8(9)14(17,18)19)22-10-7-3-4-21-12(16)11(7)23-13(10)20/h1-5,22H,20H2
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CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387606
PNG
(N3-(3-Chloro-4- fluorophenyl)- 5,7-difluoro- furo[...)
Show SMILES Nc1oc2c(F)nc(F)cc2c1Nc1ccc(F)c(Cl)c1
Show InChI InChI=1S/C13H7ClF3N3O/c14-7-3-5(1-2-8(7)15)19-10-6-4-9(16)20-12(17)11(6)21-13(10)18/h1-4,19H,18H2
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CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387611
PNG
(4-(2-Amino-3- ((3-chloro-4- fluorophenyl) amino)fu...)
Show SMILES CNC(=O)c1cc(ccn1)-c1nccc2c(Nc3ccc(F)c(Cl)c3)c(N)oc12
Show InChI InChI=1S/C20H15ClFN5O2/c1-24-20(28)15-8-10(4-6-25-15)16-18-12(5-7-26-16)17(19(23)29-18)27-11-2-3-14(22)13(21)9-11/h2-9,27H,23H2,1H3,(H,24,28)
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CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387614
PNG
(N3-(3,4- Difluoro- phenyl)-7-(2- methylpyridin- 4-...)
Show SMILES Cc1cc(ccn1)-c1nccc2c(Nc3ccc(F)c(F)c3)c(N)oc12
Show InChI InChI=1S/C19H14F2N4O/c1-10-8-11(4-6-23-10)16-18-13(5-7-24-16)17(19(22)26-18)25-12-2-3-14(20)15(21)9-12/h2-9,25H,22H2,1H3
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CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387615
PNG
(N3-(3-Chloro-4- fluorophenyl)- 7-(3- (trifluoro- m...)
Show SMILES Nc1oc2c(nccc2c1Nc1ccc(F)c(Cl)c1)-c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C20H12ClF4N3O/c21-14-9-12(4-5-15(14)22)28-17-13-6-7-27-16(18(13)29-19(17)26)10-2-1-3-11(8-10)20(23,24)25/h1-9,28H,26H2
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CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387618
PNG
(N3-(2- Chlorophenyl)- 7-(pyridin-4- yl)furo[2,3- c...)
Show SMILES Nc1oc2c(nccc2c1Nc1ccccc1Cl)-c1ccncc1
Show InChI InChI=1S/C18H13ClN4O/c19-13-3-1-2-4-14(13)23-16-12-7-10-22-15(17(12)24-18(16)20)11-5-8-21-9-6-11/h1-10,23H,20H2
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CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387643
PNG
(4-(2-Amino-3- ((4- fluorophenyl) amino)furo[2,3- c...)
Show SMILES CNC(=O)c1cc(ccn1)-c1nccc2c(Nc3ccc(F)cc3)c(N)oc12
Show InChI InChI=1S/C20H16FN5O2/c1-23-20(27)15-10-11(6-8-24-15)16-18-14(7-9-25-16)17(19(22)28-18)26-13-4-2-12(21)3-5-13/h2-10,26H,22H2,1H3,(H,23,27)
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CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387647
PNG
(5-Fluoro-N3-(4- fluorophenyl) furo[2,3-c] pyridine...)
Show SMILES Nc1oc2cnc(F)cc2c1Nc1ccc(F)cc1
Show InChI InChI=1S/C13H9F2N3O/c14-7-1-3-8(4-2-7)18-12-9-5-11(15)17-6-10(9)19-13(12)16/h1-6,18H,16H2
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CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387652
PNG
(N3-(3-Chloro-4- fluorophenyl)- 7-phenylbenzo [b]th...)
Show SMILES Nc1sc2c(cccc2c1Nc1ccc(F)c(Cl)c1)-c1ccccc1
Show InChI InChI=1S/C20H14ClFN2S/c21-16-11-13(9-10-17(16)22)24-18-15-8-4-7-14(19(15)25-20(18)23)12-5-2-1-3-6-12/h1-11,24H,23H2
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CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387660
PNG
(5-Fluoro-N3-(4- fluorophenyl)- 7-(2- methylpyridin...)
Show SMILES Cc1cc(ccn1)-c1nc(F)cc2c(Nc3ccc(F)cc3)c(N)oc12
Show InChI InChI=1S/C19H14F2N4O/c1-10-8-11(6-7-23-10)16-18-14(9-15(21)25-16)17(19(22)26-18)24-13-4-2-12(20)3-5-13/h2-9,24H,22H2,1H3
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CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387671
PNG
(4-(2-Amino-3- ((3-chloro-4- fluorophenyl) amino)fu...)
Show SMILES Nc1oc2c(nccc2c1Nc1ccc(F)c(Cl)c1)-c1ccnc(c1)C(=O)Nc1ccccc1
Show InChI InChI=1S/C25H17ClFN5O2/c26-18-13-16(6-7-19(18)27)31-22-17-9-11-30-21(23(17)34-24(22)28)14-8-10-29-20(12-14)25(33)32-15-4-2-1-3-5-15/h1-13,31H,28H2,(H,32,33)
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n/an/a<200n/an/an/an/an/an/a



CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387674
PNG
(4-(2-Amino-3- ((3-chloro-4- fluorophenyl) amino)fu...)
Show SMILES CC(C)CNC(=O)c1cc(ccn1)-c1nccc2c(Nc3ccc(F)c(Cl)c3)c(N)oc12
Show InChI InChI=1S/C23H21ClFN5O2/c1-12(2)11-29-23(31)18-9-13(5-7-27-18)19-21-15(6-8-28-19)20(22(26)32-21)30-14-3-4-17(25)16(24)10-14/h3-10,12,30H,11,26H2,1-2H3,(H,29,31)
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n/an/a<200n/an/an/an/an/an/a



CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387687
PNG
(N3-(4- Fluorophenyl)- 7-(2- methylpyridin- 4-yl)be...)
Show SMILES Cc1cc(ccn1)-c1cccc2c(Nc3ccc(F)cc3)c(N)sc12
Show InChI InChI=1S/C20H16FN3S/c1-12-11-13(9-10-23-12)16-3-2-4-17-18(20(22)25-19(16)17)24-15-7-5-14(21)6-8-15/h2-11,24H,22H2,1H3
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CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387688
PNG
(N3-(3-Chloro-4- fluorophenyl)- 5-methyl-7-(2- meth...)
Show SMILES Cc1cc(ccn1)-c1nc(C)cc2c(Nc3ccc(F)c(Cl)c3)c(N)oc12
Show InChI InChI=1S/C20H16ClFN4O/c1-10-7-12(5-6-24-10)17-19-14(8-11(2)25-17)18(20(23)27-19)26-13-3-4-16(22)15(21)9-13/h3-9,26H,23H2,1-2H3
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CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387355
PNG
(N3-(3-Chloro- 4-fluorophenyl) furo[3,2- b]pyridine...)
Show SMILES Nc1oc2cccnc2c1Nc1ccc(F)c(Cl)c1
Show InChI InChI=1S/C13H9ClFN3O/c14-8-6-7(3-4-9(8)15)18-12-11-10(19-13(12)16)2-1-5-17-11/h1-6,18H,16H2
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n/an/a<200n/an/an/an/an/an/a



CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387469
PNG
(N3-(3-Chloro-4- fluorophenyl)- 7-(pyridin-4- yl)fu...)
Show SMILES Nc1oc2c(nccc2c1Nc1ccc(F)c(Cl)c1)-c1ccncc1
Show InChI InChI=1S/C18H12ClFN4O/c19-13-9-11(1-2-14(13)20)24-16-12-5-8-23-15(17(12)25-18(16)21)10-3-6-22-7-4-10/h1-9,24H,21H2
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CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))		BDBM387473
PNG
(N3-(3-Chloro-4- fluorophenyl)- 7-(3- chlorophenyl)...)
Show SMILES Nc1oc2c(nccc2c1Nc1ccc(F)c(Cl)c1)-c1cccc(Cl)c1
Show InChI InChI=1S/C19H12Cl2FN3O/c20-11-3-1-2-10(8-11)16-18-13(6-7-24-16)17(19(23)26-18)25-12-4-5-15(22)14(21)9-12/h1-9,25H,23H2
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n/an/a<200n/an/an/an/an/an/a



CURADEV PHARMA, PVT. LTD.

US Patent


Assay Description
Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...

US Patent US10294212 (2019)

More data for this
Ligand-Target Pair
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