BindingDB logo
myBDB logout

Patent code US10301320

Compile Data Set for Download or QSAR
Found 27 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM347364
PNG
(US10301320, ID SW206980 | US9789116, SW206980)
Show SMILES CCCCS(=O)c1sc2nc(ccc2c1N)-c1cccs1
Show InChI InChI=1/C15H16N2OS3/c1-2-3-9-21(18)15-13(16)10-6-7-11(17-14(10)20-15)12-5-4-8-19-12/h4-8H,2-3,9,16H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 0.970n/an/an/an/an/an/a



University of Kentucky Research Foundation; Case Western Reserve University; Board of Regents of the University of Texas System

US Patent


Assay Description
This Example provides data on a group of structural analogues of SW033291. Data provided includes level of induction of a 15-PGDH-luciferase fusion g...


US Patent US10301320 (2019)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM347359
PNG
(US10301320, ID SW033291 | US9789116, SW033291)
Show SMILES CCCCS(=O)c1sc2nc(cc(-c3ccccc3)c2c1N)-c1cccs1
Show InChI InChI=1/C21H20N2OS3/c1-2-3-12-27(24)21-19(22)18-15(14-8-5-4-6-9-14)13-16(23-20(18)26-21)17-10-7-11-25-17/h4-11,13H,2-3,12,22H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1.23n/an/an/an/an/an/a



University of Kentucky Research Foundation; Case Western Reserve University; Board of Regents of the University of Texas System

US Patent


Assay Description
This Example provides data on a group of structural analogues of SW033291. Data provided includes level of induction of a 15-PGDH-luciferase fusion g...


US Patent US10301320 (2019)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM347368
PNG
(US10301320, ID SW208066 | US9789116, SW208066)
Show SMILES CCCCS(=O)c1sc2nc(cc(-c3ccccc3)c2c1N)-c1nccs1
Show InChI InChI=1/C20H19N3OS3/c1-2-3-11-27(24)20-17(21)16-14(13-7-5-4-6-8-13)12-15(23-19(16)26-20)18-22-9-10-25-18/h4-10,12H,2-3,11,21H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1.37n/an/an/an/an/an/a



University of Kentucky Research Foundation; Case Western Reserve University; Board of Regents of the University of Texas System

US Patent


Assay Description
This Example provides data on a group of structural analogues of SW033291. Data provided includes level of induction of a 15-PGDH-luciferase fusion g...


US Patent US10301320 (2019)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM347365
PNG
(US10301320, ID SW206992 | US9789116, SW206992)
Show SMILES CCCCS(=O)c1sc2nc(ccc2c1N)-c1nccs1
Show InChI InChI=1/C14H15N3OS3/c1-2-3-8-21(18)14-11(15)9-4-5-10(17-12(9)20-14)13-16-6-7-19-13/h4-7H,2-3,8,15H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1.41n/an/an/an/an/an/a



University of Kentucky Research Foundation; Case Western Reserve University; Board of Regents of the University of Texas System

US Patent


Assay Description
This Example provides data on a group of structural analogues of SW033291. Data provided includes level of induction of a 15-PGDH-luciferase fusion g...


US Patent US10301320 (2019)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM393003
PNG
(US10301320, ID SW208067)
Show SMILES CCCCSc1sc2nc(nc(-c3ccccc3)c2c1N)-c1cccs1
Show InChI InChI=1S/C20H19N3S3/c1-2-3-11-25-20-16(21)15-17(13-8-5-4-6-9-13)22-18(23-19(15)26-20)14-10-7-12-24-14/h4-10,12H,2-3,11,21H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 2.40n/an/an/an/an/an/a



University of Kentucky Research Foundation; Case Western Reserve University; Board of Regents of the University of Texas System

US Patent


Assay Description
This Example provides data on a group of structural analogues of SW033291. Data provided includes level of induction of a 15-PGDH-luciferase fusion g...


US Patent US10301320 (2019)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM347375
PNG
(US10301320, ID SW208080 | US9789116, SW208080)
Show SMILES CCCCCS(=O)c1sc2nc(cc(-c3ccccc3)c2c1N)-c1cccs1
Show InChI InChI=1/C22H22N2OS3/c1-2-3-7-13-28(25)22-20(23)19-16(15-9-5-4-6-10-15)14-17(24-21(19)27-22)18-11-8-12-26-18/h4-6,8-12,14H,2-3,7,13,23H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 2.64n/an/an/an/an/an/a



University of Kentucky Research Foundation; Case Western Reserve University; Board of Regents of the University of Texas System

US Patent


Assay Description
This Example provides data on a group of structural analogues of SW033291. Data provided includes level of induction of a 15-PGDH-luciferase fusion g...


US Patent US10301320 (2019)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM347367
PNG
(US10301320, ID SW208065 | US9789116, SW208065)
Show SMILES CCCCS(=O)c1sc2nc(nc(-c3ccccc3)c2c1N)-c1ccccc1
Show InChI InChI=1/C22H21N3OS2/c1-2-3-14-28(26)22-18(23)17-19(15-10-6-4-7-11-15)24-20(25-21(17)27-22)16-12-8-5-9-13-16/h4-13H,2-3,14,23H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 4.87n/an/an/an/an/an/a



University of Kentucky Research Foundation; Case Western Reserve University; Board of Regents of the University of Texas System

US Patent


Assay Description
This Example provides data on a group of structural analogues of SW033291. Data provided includes level of induction of a 15-PGDH-luciferase fusion g...


US Patent US10301320 (2019)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM347376
PNG
(US10301320, ID SW208081 | US9789116, SW208081)
Show SMILES CCCCCCS(=O)c1sc2nc(cc(-c3ccccc3)c2c1N)-c1cccs1
Show InChI InChI=1/C23H24N2OS3/c1-2-3-4-8-14-29(26)23-21(24)20-17(16-10-6-5-7-11-16)15-18(25-22(20)28-23)19-12-9-13-27-19/h5-7,9-13,15H,2-4,8,14,24H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 18n/an/an/an/an/an/a



University of Kentucky Research Foundation; Case Western Reserve University; Board of Regents of the University of Texas System

US Patent


Assay Description
This Example provides data on a group of structural analogues of SW033291. Data provided includes level of induction of a 15-PGDH-luciferase fusion g...


US Patent US10301320 (2019)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM347374
PNG
(US10301320, ID SW208078 | US9789116, SW208078)
Show SMILES CCCCS(=O)(=O)c1sc2nc(cc(-c3ccccc3)c2c1N)-c1cccs1
Show InChI InChI=1S/C21H20N2O2S3/c1-2-3-12-28(24,25)21-19(22)18-15(14-8-5-4-6-9-14)13-16(23-20(18)27-21)17-10-7-11-26-17/h4-11,13H,2-3,12,22H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 25n/an/an/an/an/an/a



University of Kentucky Research Foundation; Case Western Reserve University; Board of Regents of the University of Texas System

US Patent


Assay Description
This Example provides data on a group of structural analogues of SW033291. Data provided includes level of induction of a 15-PGDH-luciferase fusion g...


US Patent US10301320 (2019)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM347359
PNG
(US10301320, ID SW033291 | US9789116, SW033291)
Show SMILES CCCCS(=O)c1sc2nc(cc(-c3ccccc3)c2c1N)-c1cccs1
Show InChI InChI=1/C21H20N2OS3/c1-2-3-12-27(24)21-19(22)18-15(14-8-5-4-6-9-14)13-16(23-20(18)26-21)17-10-7-11-25-17/h4-11,13H,2-3,12,22H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 56.6n/an/an/an/an/an/a



University of Kentucky Research Foundation; Case Western Reserve University; Board of Regents of the University of Texas System

US Patent


Assay Description
This Example provides data on a group of structural analogues of SW033291. Data provided includes level of induction of a 15-PGDH-luciferase fusion g...


US Patent US10301320 (2019)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM347359
PNG
(US10301320, ID SW033291 | US9789116, SW033291)
Show SMILES CCCCS(=O)c1sc2nc(cc(-c3ccccc3)c2c1N)-c1cccs1
Show InChI InChI=1/C21H20N2OS3/c1-2-3-12-27(24)21-19(22)18-15(14-8-5-4-6-9-14)13-16(23-20(18)26-21)17-10-7-11-25-17/h4-11,13H,2-3,12,22H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 56.6n/an/an/an/an/an/a



University of Kentucky Research Foundation; Case Western Reserve University; Board of Regents of the University of Texas System

US Patent


Assay Description
This Example provides data on a group of structural analogues of SW033291. Data provided includes level of induction of a 15-PGDH-luciferase fusion g...


US Patent US10301320 (2019)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM348749
PNG
(US10301320, ID SW208079 | US9790233, ID SW208079)
Show SMILES CS(=O)c1sc2nc(cc(-c3ccccc3)c2c1N)-c1cccs1
Show InChI InChI=1/C18H14N2OS3/c1-24(21)18-16(19)15-12(11-6-3-2-4-7-11)10-13(20-17(15)23-18)14-8-5-9-22-14/h2-10H,19H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 125n/an/an/an/an/an/a



University of Kentucky Research Foundation; Case Western Reserve University; Board of Regents of the University of Texas System

US Patent


Assay Description
This Example provides data on a group of structural analogues of SW033291. Data provided includes level of induction of a 15-PGDH-luciferase fusion g...


US Patent US10301320 (2019)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM347366
PNG
(US10301320, ID SW208064 | US9789116, SW208064)
Show SMILES CCCCS(=O)c1sc2ncccc2c1N
Show InChI InChI=1/C11H14N2OS2/c1-2-3-7-16(14)11-9(12)8-5-4-6-13-10(8)15-11/h4-6H,2-3,7,12H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 151n/an/an/an/an/an/a



University of Kentucky Research Foundation; Case Western Reserve University; Board of Regents of the University of Texas System

US Patent


Assay Description
This Example provides data on a group of structural analogues of SW033291. Data provided includes level of induction of a 15-PGDH-luciferase fusion g...


US Patent US10301320 (2019)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM393010
PNG
(US10301320, ETSW ID SW202989)
Show SMILES COc1ccc(cc1)S(=O)(=O)N(CC(=O)Nc1ccncc1)c1cc(OC)ccc1OC
Show InChI InChI=1S/C22H23N3O6S/c1-29-17-4-7-19(8-5-17)32(27,28)25(15-22(26)24-16-10-12-23-13-11-16)20-14-18(30-2)6-9-21(20)31-3/h4-14H,15H2,1-3H3,(H,23,24,26)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 427n/an/an/an/an/an/a



University of Kentucky Research Foundation; Case Western Reserve University; Board of Regents of the University of Texas System

US Patent


Assay Description
This Example provides data on a group of structural analogues of SW033291. Data provided includes level of induction of a 15-PGDH-luciferase fusion g...


US Patent US10301320 (2019)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM53662
PNG
(2-Methanesulfonyl-4-phenyl-6-thiophen-2-yl-thieno[...)
Show SMILES CS(=O)(=O)c1sc2nc(cc(-c3ccccc3)c2c1N)-c1cccs1
Show InChI InChI=1S/C18H14N2O2S3/c1-25(21,22)18-16(19)15-12(11-6-3-2-4-7-11)10-13(20-17(15)24-18)14-8-5-9-23-14/h2-10H,19H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 525n/an/an/an/an/an/a



University of Kentucky Research Foundation; Case Western Reserve University; Board of Regents of the University of Texas System

US Patent


Assay Description
This Example provides data on a group of structural analogues of SW033291. Data provided includes level of induction of a 15-PGDH-luciferase fusion g...


US Patent US10301320 (2019)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM393008
PNG
(US10301320, ETSW ID SW202938)
Show SMILES COc1ccc(OC)c(c1)N(CC(=O)Nc1ccncc1)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C21H21N3O5S/c1-28-17-8-9-20(29-2)19(14-17)24(30(26,27)18-6-4-3-5-7-18)15-21(25)23-16-10-12-22-13-11-16/h3-14H,15H2,1-2H3,(H,22,23,25)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 2.67E+3n/an/an/an/an/an/a



University of Kentucky Research Foundation; Case Western Reserve University; Board of Regents of the University of Texas System

US Patent


Assay Description
This Example provides data on a group of structural analogues of SW033291. Data provided includes level of induction of a 15-PGDH-luciferase fusion g...


US Patent US10301320 (2019)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM393012
PNG
(US10301320, ETSW ID SW203685)
Show SMILES COc1ccc(OC)c(c1)N(CC(=O)Nc1ccnnc1)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C20H20N4O5S/c1-28-16-8-9-19(29-2)18(12-16)24(30(26,27)17-6-4-3-5-7-17)14-20(25)23-15-10-11-21-22-13-15/h3-13H,14H2,1-2H3,(H,21,23,25)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 5.00E+3n/an/an/an/an/an/a



University of Kentucky Research Foundation; Case Western Reserve University; Board of Regents of the University of Texas System

US Patent


Assay Description
This Example provides data on a group of structural analogues of SW033291. Data provided includes level of induction of a 15-PGDH-luciferase fusion g...


US Patent US10301320 (2019)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM393007
PNG
(US10301320, ETSW ID SW202940)
Show SMILES COc1ccc(cc1)S(=O)(=O)N(CC(=O)Nc1cccnc1)c1cc(OC)ccc1OC
Show InChI InChI=1S/C22H23N3O6S/c1-29-17-6-9-19(10-7-17)32(27,28)25(15-22(26)24-16-5-4-12-23-14-16)20-13-18(30-2)8-11-21(20)31-3/h4-14H,15H2,1-3H3,(H,24,26)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 5.00E+3n/an/an/an/an/an/a



University of Kentucky Research Foundation; Case Western Reserve University; Board of Regents of the University of Texas System

US Patent


Assay Description
This Example provides data on a group of structural analogues of SW033291. Data provided includes level of induction of a 15-PGDH-luciferase fusion g...


US Patent US10301320 (2019)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM393011
PNG
(US10301320, ETSW ID SW203683)
Show SMILES COc1ccc(OC)c(c1)N(CC(=O)Nc1cncnc1)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C20H20N4O5S/c1-28-16-8-9-19(29-2)18(10-16)24(30(26,27)17-6-4-3-5-7-17)13-20(25)23-15-11-21-14-22-12-15/h3-12,14H,13H2,1-2H3,(H,23,25)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 7.00E+3n/an/an/an/an/an/a



University of Kentucky Research Foundation; Case Western Reserve University; Board of Regents of the University of Texas System

US Patent


Assay Description
This Example provides data on a group of structural analogues of SW033291. Data provided includes level of induction of a 15-PGDH-luciferase fusion g...


US Patent US10301320 (2019)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM347360
PNG
(US10301320, ID SW206976 | US9789116, SW206976)
Show SMILES CCCCC(=O)c1sc2nc(cc(-c3ccccc3)c2c1N)-c1cccs1
Show InChI InChI=1S/C22H20N2OS2/c1-2-3-10-17(25)21-20(23)19-15(14-8-5-4-6-9-14)13-16(24-22(19)27-21)18-11-7-12-26-18/h4-9,11-13H,2-3,10,23H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>7.50E+3n/an/an/an/an/an/a



University of Kentucky Research Foundation; Case Western Reserve University; Board of Regents of the University of Texas System

US Patent


Assay Description
This Example provides data on a group of structural analogues of SW033291. Data provided includes level of induction of a 15-PGDH-luciferase fusion g...


US Patent US10301320 (2019)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM347371
PNG
(US10301320, ID SW208069 | US9789116, SW208069)
Show SMILES CCCCS(=O)c1ncccc1[N+]([O-])=O
Show InChI InChI=1/C9H12N2O3S/c1-2-3-7-15(14)9-8(11(12)13)5-4-6-10-9/h4-6H,2-3,7H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>7.50E+3n/an/an/an/an/an/a



University of Kentucky Research Foundation; Case Western Reserve University; Board of Regents of the University of Texas System

US Patent


Assay Description
This Example provides data on a group of structural analogues of SW033291. Data provided includes level of induction of a 15-PGDH-luciferase fusion g...


US Patent US10301320 (2019)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM347372
PNG
(US10301320, ID SW208070 | US9789116, SW208070)
Show SMILES CCCCS(=O)c1ncccc1N
Show InChI InChI=1/C9H14N2OS/c1-2-3-7-13(12)9-8(10)5-4-6-11-9/h4-6H,2-3,7,10H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>7.50E+3n/an/an/an/an/an/a



University of Kentucky Research Foundation; Case Western Reserve University; Board of Regents of the University of Texas System

US Patent


Assay Description
This Example provides data on a group of structural analogues of SW033291. Data provided includes level of induction of a 15-PGDH-luciferase fusion g...


US Patent US10301320 (2019)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM347370
PNG
(US10301320, ID SW208068 | US9789116, SW208068)
Show SMILES CCCCSc1ncccc1N
Show InChI InChI=1S/C9H14N2S/c1-2-3-7-12-9-8(10)5-4-6-11-9/h4-6H,2-3,7,10H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>7.50E+3n/an/an/an/an/an/a



University of Kentucky Research Foundation; Case Western Reserve University; Board of Regents of the University of Texas System

US Patent


Assay Description
This Example provides data on a group of structural analogues of SW033291. Data provided includes level of induction of a 15-PGDH-luciferase fusion g...


US Patent US10301320 (2019)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM347362
PNG
(US10301320, ID SW206978 | US9789116, SW206978)
Show SMILES CCOC(=O)c1sc2nc(cc(-c3ccccc3)c2c1N)-c1cccs1
Show InChI InChI=1S/C20H16N2O2S2/c1-2-24-20(23)18-17(21)16-13(12-7-4-3-5-8-12)11-14(22-19(16)26-18)15-9-6-10-25-15/h3-11H,2,21H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>7.50E+3n/an/an/an/an/an/a



University of Kentucky Research Foundation; Case Western Reserve University; Board of Regents of the University of Texas System

US Patent


Assay Description
This Example provides data on a group of structural analogues of SW033291. Data provided includes level of induction of a 15-PGDH-luciferase fusion g...


US Patent US10301320 (2019)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM347363
PNG
(US10301320, ID SW206979 | US9789116, SW206979)
Show SMILES Nc1c(sc2nc(cc(-c3ccccc3)c12)-c1cccs1)C(O)=O
Show InChI InChI=1S/C18H12N2O2S2/c19-15-14-11(10-5-2-1-3-6-10)9-12(13-7-4-8-23-13)20-17(14)24-16(15)18(21)22/h1-9H,19H2,(H,21,22)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>7.50E+3n/an/an/an/an/an/a



University of Kentucky Research Foundation; Case Western Reserve University; Board of Regents of the University of Texas System

US Patent


Assay Description
This Example provides data on a group of structural analogues of SW033291. Data provided includes level of induction of a 15-PGDH-luciferase fusion g...


US Patent US10301320 (2019)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM347361
PNG
(US10301320, ID SW206977 | US9789116, SW206977)
Show SMILES CCCNC(=O)c1sc2nc(cc(-c3ccccc3)c2c1N)-c1cccs1
Show InChI InChI=1S/C21H19N3OS2/c1-2-10-23-20(25)19-18(22)17-14(13-7-4-3-5-8-13)12-15(24-21(17)27-19)16-9-6-11-26-16/h3-9,11-12H,2,10,22H2,1H3,(H,23,25)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>7.50E+3n/an/an/an/an/an/a



University of Kentucky Research Foundation; Case Western Reserve University; Board of Regents of the University of Texas System

US Patent


Assay Description
This Example provides data on a group of structural analogues of SW033291. Data provided includes level of induction of a 15-PGDH-luciferase fusion g...


US Patent US10301320 (2019)

More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM393009
PNG
(US10301320, ETSW ID SW202988)
Show SMILES COc1ccc(OC)c(c1)N(CC(=O)Nc1ccc(C)nc1)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C22H23N3O5S/c1-16-9-10-17(14-23-16)24-22(26)15-25(31(27,28)19-7-5-4-6-8-19)20-13-18(29-2)11-12-21(20)30-3/h4-14H,15H2,1-3H3,(H,24,26)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1.00E+4n/an/an/an/an/an/a



University of Kentucky Research Foundation; Case Western Reserve University; Board of Regents of the University of Texas System

US Patent


Assay Description
This Example provides data on a group of structural analogues of SW033291. Data provided includes level of induction of a 15-PGDH-luciferase fusion g...


US Patent US10301320 (2019)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%