Compile Data Set for Download or QSAR
maximum 50k data
Found 23 Enz. Inhib. hit(s) with all data for entry = 3227
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM162322(US10307427, Compound 13 | US9051313, 13)
Affinity DataIC50:  0.700nMAssay Description:The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection (6.1). This is a competitive...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM162310(US10307427, Compound 1 | US9051313, 1)
Affinity DataIC50:  1.44nMAssay Description:The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection (6.1). This is a competitive...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM162311(US10307427, Compound 2 | US9051313, 2)
Affinity DataIC50:  1.58nMAssay Description:The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection (6.1). This is a competitive...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM394380((S)-4-(4-cyclopropyl-1H-imidazol-1-yl)-5-(3-hydrox...)
Affinity DataIC50:  1.69nMAssay Description:The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection (6.1). This is a competitive...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM394384((S)-5-(azetidin-1-yl)-4-(4-cyclopropyl-1H-imidazol...)
Affinity DataIC50:  1.70nMAssay Description:The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection (6.1). This is a competitive...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM162323(US10307427, Compound 14 | US9051313, 14)
Affinity DataIC50:  1.80nMAssay Description:The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection (6.1). This is a competitive...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM394381((S)-4-(4-cyclopropyl-1H-imidazol-1-yl)-5-(dimethyl...)
Affinity DataIC50:  1.88nMAssay Description:The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection (6.1). This is a competitive...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM162318(US10307427, Compound 9 | US9051313, 9)
Affinity DataIC50:  1.90nMAssay Description:The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection (6.1). This is a competitive...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM162321(US10307427, Compound 12 | US9051313, 12)
Affinity DataIC50:  2nMAssay Description:The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection (6.1). This is a competitive...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM162325(US10307427, Compound 16 | US9051313, 16)
Affinity DataIC50:  2.10nMAssay Description:The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection (6.1). This is a competitive...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM162320(US10307427, Compound 11 | US9051313, 11)
Affinity DataIC50:  2.20nMAssay Description:The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection (6.1). This is a competitive...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM394385((S)-4-(4-cyclopropyl-1H-imidazol-1-yl)-5-(pyrrolid...)
Affinity DataIC50:  2.20nMAssay Description:The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection (6.1). This is a competitive...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM162315(US10307427, Compound 6 | US9051313, 6)
Affinity DataIC50:  2.40nMAssay Description:The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection (6.1). This is a competitive...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM162324(US10307427, Compound 15 | US9051313, 15)
Affinity DataIC50:  2.5nMAssay Description:The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection (6.1). This is a competitive...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM394379((S)-4-(4-cyclopropyl-1H-imidazol-1-yl)-5-morpholin...)
Affinity DataIC50:  2.62nMAssay Description:The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection (6.1). This is a competitive...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM162319(US10307427, Compound 10 | US9051313, 10)
Affinity DataIC50:  3nMAssay Description:The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection (6.1). This is a competitive...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM162326(US10307427, Compound 17 | US9051313, 17)
Affinity DataIC50:  3.10nMAssay Description:The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection (6.1). This is a competitive...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM139540(US10189849, staurosporine | US10307427, Staurospor...)
Affinity DataIC50:  6.30nMAssay Description:The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection (6.1). This is a competitive...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM394381((S)-4-(4-cyclopropyl-1H-imidazol-1-yl)-5-(dimethyl...)
Affinity DataEC50:  7.12nMAssay Description:The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection (6.1). This is a competitive...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM394380((S)-4-(4-cyclopropyl-1H-imidazol-1-yl)-5-(3-hydrox...)
Affinity DataEC50:  5.21nMAssay Description:The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection (6.1). This is a competitive...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM162311(US10307427, Compound 2 | US9051313, 2)
Affinity DataEC50:  11.2nMAssay Description:The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection (6.1). This is a competitive...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM394379((S)-4-(4-cyclopropyl-1H-imidazol-1-yl)-5-morpholin...)
Affinity DataEC50:  6.74nMAssay Description:The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection (6.1). This is a competitive...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM162310(US10307427, Compound 1 | US9051313, 1)
Affinity DataEC50:  13.2nMAssay Description:The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection (6.1). This is a competitive...More data for this Ligand-Target Pair
In DepthDetails US Patent