Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with all data for entry = 3229
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Horizon Orphan

US Patent
LigandPNGBDBM394396(US10308607, Compound II)
Affinity DataIC50:  16nMAssay Description:Fucosidase inhibition was assessed by preparing a reaction mixture of 50 mM phosphate-citrate pH 4.5, 5 mM MgCl2, 640 nM 4-methylumbelliferyl-alpha-L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Horizon Orphan

US Patent
LigandPNGBDBM394397(US10308607, Compound III)
Affinity DataIC50:  59nMAssay Description:Fucosidase inhibition was assessed by preparing a reaction mixture of 50 mM phosphate-citrate pH 4.5, 5 mM MgCl2, 640 nM 4-methylumbelliferyl-alpha-L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
Horizon Orphan

US Patent
LigandPNGBDBM394398(US10308607, Compound IV)
Affinity DataIC50:  1.50E+3nMAssay Description:Fucosidase inhibition was assessed by preparing a reaction mixture of 50 mM phosphate-citrate pH 4.5, 5 mM MgCl2, 640 nM 4-methylumbelliferyl-alpha-L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent