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Found 10 Enz. Inhib. hit(s) with all data for entry = 3242
TargetType-2 angiotensin II receptor(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM395229(US10308628, Compound 1)
Affinity DataKi:  7nMAssay Description:15 μL of [125I]CGP 42112A, at a final concentration of 0.05 nM was added to wells of assay plate.Membranes were dispersed using a 21 gauge needl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetType-2 angiotensin II receptor(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM395230(US10308628, Compound 2)
Affinity DataKi:  9nMAssay Description:15 μL of [125I]CGP 42112A, at a final concentration of 0.05 nM was added to wells of assay plate.Membranes were dispersed using a 21 gauge needl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetType-2 angiotensin II receptor(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM395233(US10308628, Compound 5)
Affinity DataKi:  9nMAssay Description:15 μL of [125I]CGP 42112A, at a final concentration of 0.05 nM was added to wells of assay plate.Membranes were dispersed using a 21 gauge needl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetType-2 angiotensin II receptor(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM395232(US10308628, Compound 4)
Affinity DataKi:  15nMAssay Description:15 μL of [125I]CGP 42112A, at a final concentration of 0.05 nM was added to wells of assay plate.Membranes were dispersed using a 21 gauge needl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetType-2 angiotensin II receptor(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM395231(US10308628, Compound 3)
Affinity DataKi:  17nMAssay Description:15 μL of [125I]CGP 42112A, at a final concentration of 0.05 nM was added to wells of assay plate.Membranes were dispersed using a 21 gauge needl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetType-2 angiotensin II receptor(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM395238(US10308628, Compound 10)
Affinity DataKi:  21nMAssay Description:15 μL of [125I]CGP 42112A, at a final concentration of 0.05 nM was added to wells of assay plate.Membranes were dispersed using a 21 gauge needl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetType-2 angiotensin II receptor(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM395237(US10308628, Compound 9)
Affinity DataKi:  23nMAssay Description:15 μL of [125I]CGP 42112A, at a final concentration of 0.05 nM was added to wells of assay plate.Membranes were dispersed using a 21 gauge needl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetType-2 angiotensin II receptor(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM395234(US10308628, Compound 6)
Affinity DataKi:  26nMAssay Description:15 μL of [125I]CGP 42112A, at a final concentration of 0.05 nM was added to wells of assay plate.Membranes were dispersed using a 21 gauge needl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetType-2 angiotensin II receptor(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM395236(US10308628, Compound 8)
Affinity DataKi:  30nMAssay Description:15 μL of [125I]CGP 42112A, at a final concentration of 0.05 nM was added to wells of assay plate.Membranes were dispersed using a 21 gauge needl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetType-2 angiotensin II receptor(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM395235(US10308628, Compound 7)
Affinity DataKi:  50nMAssay Description:15 μL of [125I]CGP 42112A, at a final concentration of 0.05 nM was added to wells of assay plate.Membranes were dispersed using a 21 gauge needl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent