Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Epoxide hydratase (Homo sapiens (Human)) | BDBM398054![]() (US10322118, Urea-Based Scaffold Entry 1) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | Article US Patent | n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Dartmouth College US Patent | Assay Description The first step in characterizing the two compounds identified by high throughput screening was to verify that the inhibition was reproducible using f... | US Patent US10322118 (2019) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KW5JC9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epoxide hydratase (Homo sapiens (Human)) | BDBM50327827![]() (1-(4-Nitrophenyl)-3-(1-propionylpiperidin-4-yl)ure...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem | Article US Patent | n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
Dartmouth College US Patent | Assay Description The first step in characterizing the two compounds identified by high throughput screening was to verify that the inhibition was reproducible using f... | US Patent US10322118 (2019) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KW5JC9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CFTR inhibitory factor, Cif (Pseudomonas aeruginosa (strain UCBPP-PA14)) | BDBM398056![]() (US10322118, Urea-Based Scaffold Entry 4) | PDB UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | Article US Patent | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Dartmouth College US Patent | Assay Description The first step in characterizing the two compounds identified by high throughput screening was to verify that the inhibition was reproducible using f... | US Patent US10322118 (2019) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KW5JC9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CFTR inhibitory factor, Cif (Pseudomonas aeruginosa (strain UCBPP-PA14)) | BDBM398055![]() (US10322118, Urea-Based Scaffold Entry 3) | PDB UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | Article US Patent | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Dartmouth College US Patent | Assay Description The first step in characterizing the two compounds identified by high throughput screening was to verify that the inhibition was reproducible using f... | US Patent US10322118 (2019) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KW5JC9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CFTR inhibitory factor, Cif (Pseudomonas aeruginosa (strain UCBPP-PA14)) | BDBM50385105![]() (CHEMBL2035874 | US10322118, Entry 8b) | PDB UniProtKB/TrEMBL GoogleScholar | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem | PDB Article US Patent | n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Dartmouth College US Patent | Assay Description The first step in characterizing the two compounds identified by high throughput screening was to verify that the inhibition was reproducible using f... | US Patent US10322118 (2019) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KW5JC9 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
CFTR inhibitory factor, Cif (Pseudomonas aeruginosa (strain UCBPP-PA14)) | BDBM18864![]() (3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]pr...) | PDB UniProtKB/TrEMBL GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | Article US Patent | n/a | n/a | 4.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Dartmouth College US Patent | Assay Description The first step in characterizing the two compounds identified by high throughput screening was to verify that the inhibition was reproducible using f... | US Patent US10322118 (2019) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KW5JC9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CFTR inhibitory factor, Cif (Pseudomonas aeruginosa (strain UCBPP-PA14)) | BDBM18862![]() (2-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]ac...) | PDB UniProtKB/TrEMBL GoogleScholar | Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents | PDB Article US Patent | n/a | n/a | 4.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Dartmouth College US Patent | Assay Description The first step in characterizing the two compounds identified by high throughput screening was to verify that the inhibition was reproducible using f... | US Patent US10322118 (2019) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KW5JC9 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
CFTR inhibitory factor, Cif (Pseudomonas aeruginosa (strain UCBPP-PA14)) | BDBM11639![]() (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) | PDB UniProtKB/TrEMBL GoogleScholar | Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article US Patent | n/a | n/a | 7.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Dartmouth College US Patent | Assay Description The first step in characterizing the two compounds identified by high throughput screening was to verify that the inhibition was reproducible using f... | US Patent US10322118 (2019) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KW5JC9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CFTR inhibitory factor, Cif (Pseudomonas aeruginosa (strain UCBPP-PA14)) | BDBM398043![]() (US10322118, Entry 1) | PDB UniProtKB/TrEMBL GoogleScholar | PC cid PC sid PDB UniChem | Article US Patent | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Dartmouth College US Patent | Assay Description The first step in characterizing the two compounds identified by high throughput screening was to verify that the inhibition was reproducible using f... | US Patent US10322118 (2019) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KW5JC9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CFTR inhibitory factor, Cif (Pseudomonas aeruginosa (strain UCBPP-PA14)) | BDBM398047![]() (US10322118, Entry 5) | PDB UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | Article US Patent | n/a | n/a | 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Dartmouth College US Patent | Assay Description The first step in characterizing the two compounds identified by high throughput screening was to verify that the inhibition was reproducible using f... | US Patent US10322118 (2019) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KW5JC9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epoxide hydratase (Homo sapiens (Human)) | BDBM398060![]() (US10322118, Urea-Based Scaffold Entry 8) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | Article US Patent | n/a | n/a | 3.33E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Dartmouth College US Patent | Assay Description The first step in characterizing the two compounds identified by high throughput screening was to verify that the inhibition was reproducible using f... | US Patent US10322118 (2019) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KW5JC9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CFTR inhibitory factor, Cif (Pseudomonas aeruginosa (strain UCBPP-PA14)) | BDBM50327827![]() (1-(4-Nitrophenyl)-3-(1-propionylpiperidin-4-yl)ure...) | PDB UniProtKB/TrEMBL GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem | Article US Patent | n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Dartmouth College US Patent | Assay Description The first step in characterizing the two compounds identified by high throughput screening was to verify that the inhibition was reproducible using f... | US Patent US10322118 (2019) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KW5JC9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CFTR inhibitory factor, Cif (Pseudomonas aeruginosa (strain UCBPP-PA14)) | BDBM398046![]() (US10322118, Entry 4) | PDB UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | Article US Patent | n/a | n/a | 8.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Dartmouth College US Patent | Assay Description The first step in characterizing the two compounds identified by high throughput screening was to verify that the inhibition was reproducible using f... | US Patent US10322118 (2019) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KW5JC9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CFTR inhibitory factor, Cif (Pseudomonas aeruginosa (strain UCBPP-PA14)) | BDBM50334276![]() (4-phenoxyaniline | CHEMBL249550 | US10322118, Entr...) | PDB UniProtKB/TrEMBL GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article US Patent | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Dartmouth College US Patent | Assay Description The first step in characterizing the two compounds identified by high throughput screening was to verify that the inhibition was reproducible using f... | US Patent US10322118 (2019) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KW5JC9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CFTR inhibitory factor, Cif (Pseudomonas aeruginosa (strain UCBPP-PA14)) | BDBM398057![]() (US10322118, Urea-Based Scaffold Entry 5) | PDB UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | Article US Patent | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Dartmouth College US Patent | Assay Description The first step in characterizing the two compounds identified by high throughput screening was to verify that the inhibition was reproducible using f... | US Patent US10322118 (2019) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KW5JC9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CFTR inhibitory factor, Cif (Pseudomonas aeruginosa (strain UCBPP-PA14)) | BDBM398059![]() (US10322118, Urea-Based Scaffold Entry 7) | PDB UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | Article US Patent | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Dartmouth College US Patent | Assay Description The first step in characterizing the two compounds identified by high throughput screening was to verify that the inhibition was reproducible using f... | US Patent US10322118 (2019) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KW5JC9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CFTR inhibitory factor, Cif (Pseudomonas aeruginosa (strain UCBPP-PA14)) | BDBM398048![]() (US10322118, Entry 6) | PDB UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | Article US Patent | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Dartmouth College US Patent | Assay Description The first step in characterizing the two compounds identified by high throughput screening was to verify that the inhibition was reproducible using f... | US Patent US10322118 (2019) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KW5JC9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CFTR inhibitory factor, Cif (Pseudomonas aeruginosa (strain UCBPP-PA14)) | BDBM398058![]() (US10322118, Urea-Based Scaffold Entry 6) | PDB UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | Article US Patent | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Dartmouth College US Patent | Assay Description The first step in characterizing the two compounds identified by high throughput screening was to verify that the inhibition was reproducible using f... | US Patent US10322118 (2019) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KW5JC9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CFTR inhibitory factor, Cif (Pseudomonas aeruginosa (strain UCBPP-PA14)) | BDBM50060966![]() (4-Phenoxy-benzoic acid | CHEMBL107518 | US10322118...) | PDB UniProtKB/TrEMBL GoogleScholar | Purchase CHEBI CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article US Patent | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Dartmouth College US Patent | Assay Description The first step in characterizing the two compounds identified by high throughput screening was to verify that the inhibition was reproducible using f... | US Patent US10322118 (2019) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KW5JC9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CFTR inhibitory factor, Cif (Pseudomonas aeruginosa (strain UCBPP-PA14)) | BDBM398051![]() (US10322118, Entry 9) | PDB UniProtKB/TrEMBL GoogleScholar | PC cid PC sid PDB UniChem | Article US Patent | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Dartmouth College US Patent | Assay Description The first step in characterizing the two compounds identified by high throughput screening was to verify that the inhibition was reproducible using f... | US Patent US10322118 (2019) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KW5JC9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CFTR inhibitory factor, Cif (Pseudomonas aeruginosa (strain UCBPP-PA14)) | BDBM398045![]() (US10322118, Entry 3) | PDB UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | Article US Patent | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Dartmouth College US Patent | Assay Description The first step in characterizing the two compounds identified by high throughput screening was to verify that the inhibition was reproducible using f... | US Patent US10322118 (2019) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KW5JC9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CFTR inhibitory factor, Cif (Pseudomonas aeruginosa (strain UCBPP-PA14)) | BDBM50115668![]() (3,5-dimethyl-4-(4'-hydroxy-3'-isopropylbenzyl)phen...) | PDB UniProtKB/TrEMBL GoogleScholar | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article US Patent | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Dartmouth College US Patent | Assay Description The first step in characterizing the two compounds identified by high throughput screening was to verify that the inhibition was reproducible using f... | US Patent US10322118 (2019) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KW5JC9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CFTR inhibitory factor, Cif (Pseudomonas aeruginosa (strain UCBPP-PA14)) | BDBM398054![]() (US10322118, Urea-Based Scaffold Entry 1) | PDB UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | Article US Patent | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Dartmouth College US Patent | Assay Description The first step in characterizing the two compounds identified by high throughput screening was to verify that the inhibition was reproducible using f... | US Patent US10322118 (2019) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KW5JC9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epoxide hydratase (Homo sapiens (Human)) | BDBM11639![]() (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article US Patent | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Dartmouth College US Patent | Assay Description The first step in characterizing the two compounds identified by high throughput screening was to verify that the inhibition was reproducible using f... | US Patent US10322118 (2019) Article DOI: null BindingDB Entry DOI: 10.7270/Q2KW5JC9 | |||||||||||
More data for this Ligand-Target Pair |